• Title/Summary/Keyword: 95%25 distribution

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K-mer Based RNA-seq Read Distribution Method For Accelerating De Novo Transcriptome Assembly

  • Kwon, Hwijun;Jung, Inuk
    • Journal of the Korea Society of Computer and Information
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    • v.25 no.8
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    • pp.1-8
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    • 2020
  • In this paper, we propose a gene family based RNA-seq read distribution method in means to accelerate the overal transcriptome assembly computation time. To measure the performance of our transcriptome sequence data distribution method, we evaluated the performance by testing four types of data sets of the Arabidopsis thaliana genome (Whole Unclassified Reads, Family-Classified Reads, Model-Classified Reads, and Randomly Classified Reads). As a result of de novo transcript assembly in distributed nodes using model classification data, the generated gene contigs matched 95% compared to the contig generated by WUR, and the execution time was reduced by 4.2 times compared to a single node environment using the same resources.

Association between Interferon-Inducible Protein 6 (IFI6) Polymorphisms and Hepatitis B Virus Clearance

  • Park, Geun-Hee;Kim, Kyoung-Yeon;Cho, Sung Won;Cheong, Jae Youn;Yu, Gyeong Im;Shin, Dong Hoon;Kwack, Kyu Bum
    • Genomics & Informatics
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    • v.11 no.1
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    • pp.15-23
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    • 2013
  • CD8+T cells are key factors mediating hepatitis B virus (HBV) clearance. However, these cells are killed through HBV-induced apoptosis during the antigen-presenting period in HBV-induced chronic liver disease (CLD) patients. Interferon-inducible protein 6 (IFI6) delays type I interferon-induced apoptosis in cells. We hypothesized that single nucleotide polymorphisms (SNPs) in the IFI6 could affect the chronicity of CLD. The present study included a discovery stage, in which 195 CLD patients, including chronic hepatitis B (HEP) and cirrhosis patients and 107 spontaneous recovery (SR) controls, were analyzed. The genotype distributions of rs2808426 (C > T) and rs10902662 (C > T) were significantly different between the SR and HEP groups (odds ratio [OR], 6.60; 95% confidence interval [CI], 1.64 to 26.52, p = 0.008 for both SNPs) and between the SR and CLD groups (OR, 4.38; 95% CI, 1.25 to 15.26; p = 0.021 and OR, 4.12; 95% CI, 1.18 to 14.44; p = 0.027, respectively). The distribution of diplotypes that contained these SNPs was significantly different between the SR and HEP groups (OR, 6.58; 95% CI, 1.63 to 25.59; p = 0.008 and OR, 0.15; 95% CI, 0.04 to 0.61; p = 0.008, respectively) and between the SR and CLD groups (OR, 4.38; 95% CI, 1.25 to 15.26; p = 0.021 and OR, 4.12; 95% CI, 1.18 to 14.44; p = 0.027, respectively). We were unable to replicate the association shown by secondary enrolled samples. A large-scale validation study should be performed to confirm the association between IFI6 and HBV clearance.

Genotype Distribution and Behavioral Risk Factor Analysis of Human Papillomavirus Infection in Uyghur Women

  • Sui, Shuang;Jiao, Zhen;Niyazi, Mayinuer;Sulaiya, Sulaiya;Lu, Ping;Qiao, You-Lin
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.10
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    • pp.5861-5865
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    • 2013
  • We investigated the distribution of HPV genotypes in Uyghur women in Xinjiang region of China, and behavioral factors which could predispose them to HPV infection. In this cross-sectional study, women aged 15-59 years were recruited by cluster sampling method in Yutian region in 2009. Liquid-based cytology samples were analyzed centrally for HPV genotype with a linear array detector. Univariate and multivariate logistic regression analyses were performed to identify behavioral risk factors for HPV infection. A total of 883 Uyghur women were recruited successfully. The prevalence of high-risk HPV and low-risk HPV were 7.25% and 1.58%, respectively; the most common HPVs were HPV16, 51, 31, 39 and 58. We found that age of first sexual intercourse was a strong predictor for HPV infection (odds ratio of 4.01 for ${\leq}15$ years versus ${\geq}25$). Having sexual partners ${\geq}3$ was the second predictor (OR 3.69, 95% CI 2.24-7.16). Cleaning the vagina after sex showed an increased risk of HPV infection (OR 2.72; 95% CI 1.98-5.13); Using the condom showed protective factors for HPV infection (OR 0.36; 95%CI0.12-0.53). HPV16, 51, 31, 39 and 58 were the priority types; the age of first sexual intercourse was identified as a major risk factor for HPV infection. Other notable risks were number of sexual partners and cleaning the vagina after sex. Changing these behavioral risk factors could help to reduce the occurrence of cervical cancer in this population.

Distribution of heavy metals and cyanide in tailings, soils, and stream sediments around Gubong disused mine (구봉광산 주변 토양에서의 중금속과 시안의 분포)

  • 김선태;윤양희;박제안;심의섭
    • Journal of Korea Soil Environment Society
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    • v.4 no.1
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    • pp.35-47
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    • 1999
  • Mine tailings, soils. stream sediments around Gubong disused mine were analyzed in order to investigate their distribution and pollution levels of heavy metals and cyanide. The average contents of As, Cd, Cu. Hg, Pb, Zn, and CN ̄ in mine tailings were 6.93$\times$$10^{3}$, 56.9, 209, 5.03, 3.25$\times$$10^{3}$, 1.89$\times$$10^{3}$, 21mg/kg respectively. The pollution indices that calculated by the tolerance level of Kloke were 42~95 and the pH values were slightly alkaline in mine tailings. The contents of heavy metals and cyanide in field soils near the mine were higher than the paddy soils. The contents of heavy metals in the stream sediment were up to that of the tailings, so contamination from the mine tailings were serious.

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The Statistics Probability Analysis of Pork-Cutting Processing Conditions for Microbial Risk Assessment (미생물 위해평가를 위한 포장돈육 가공환경조건에 대한 확률통계학적 분석)

  • Oh, Deog-Hwan;Rahman, S.M.E.;Kim, Jae-Myeong;Bahk, Gyung-Jin
    • Journal of Food Hygiene and Safety
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    • v.24 no.1
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    • pp.63-68
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    • 2009
  • The statistics probability approach for microbial risk assessment (MRA) has been recognized as an efficient method because this probability approach, which can be presented the diversity, variability, and uncertainty for the environmental factors of food processing, provide better realistic results than point estimate. This study was conducted to determine of probability statistics for the environmental factors of the pork-cutting processing i.e. the processing time, the pork meat temperature, and processing room temperature etc. As the input parameters for the MRA, triangular distribution and normal distribution were selected as an efficient probability distribution model, these distributions were analyzed by the simulation. The simulation results showed the processing time estimated 53 min as mean (5% - 22 min and 95% - 98 min), pork meat temperature estimated $4.83^{\circ}C$ as mean (5% - $2.25^{\circ}C$ and 95% - $7.12^{\circ}C$, 48.78% exceed $5^{\circ}C$), and processing room temperature estimated $17^{\circ}C$ as mean (5% - $10.92^{\circ}C$ and 95% - $22.56^{\circ}C$, 71.178% exceed $15^{\circ}C$).

Analysis of the Active Volcano Monitoring Program of China (중국의 활화산 모니터링 프로그램에 대한 분석)

  • Yun, Sung-Hyo;Chang, Cheolwoo
    • The Journal of the Petrological Society of Korea
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    • v.25 no.1
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    • pp.95-106
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    • 2016
  • The distribution of active volcanoes in China, overview of an active volcano monitoring of China, monitoring equipment status in China volcano observatory, and Changbaishan volcano observatory and volcano early warning system plan were investigated in this study.

Sasang Constitution Classification related to an aspect of distribution GCM(General Coordinative Manipulation) Body Type and Experimental Study based on the character of Static Posture and Dynamic Hyper/Hypo-mobility Pattern (사상의학의 4체질 분류에 따른 각 체질별 전신조정술 체형분포 양상과 그에 따른 정적 자세특성 및 동적 운동증감 양상에 관한 실증적 연구)

  • Moon, Sang-Eon;Joe, Hyun-Rae;Oh, Chang-Sun;Kim, Sung-Hyun
    • The Journal of Korean Physical Therapy
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    • v.17 no.4
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    • pp.505-517
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    • 2005
  • The Purposes of this study were to find complementary connectible new factors that analyzed correlation relate of Sasang Constitution and GCM Body Type in Static Posture and Dynamic Hyper/Hypo-mobility Pattern. Method of this study was asymtomatic volunteers 232(unmarried man and women), conducted from September 1 to December 31. In this main study progressing step diagnosised first, Constitution of Sasang medicine after being classified into four groups of Soyangin, Taeumin, Soeumin, Taeyangin diagnosis of GCM Body Type and progressed that related Static Posture and Dynamic Hyper/Hypo mobility Pattern. The results are as follows. Distribution of Sasang Medicine Constitution proved to be Taeyangin 13, Soyangin 66, Taeumin 67, Soeumin 86 respectively. Distribution of GCM Body Type proved I Body Type 72(31.0%), II Body Type 54(23.3%), III Body Type 89(38.4%), IV Body Type 17(7.3%). The distribution of Sasang Constitution according to GCM Body Type was that; I Body Type was distributed in the order Soeumin 34.7%(25), Taeumin 31.9%(23), Soyangin 30.6%(22), Soeumin 34.7%(25) is the most people. II Body Type was distribution of in the order Soeumin 42.6%(23), Soyangin 5.9%(14), Taeumin 24.1%(13), Soeumin 42.6%(23) is the most people. III Body Type was distribution of in the order Soeumin 37.1%(33), Taeumin 30.3%(27), Soyangin 28.1%(25), Soeumin 37.1% is the most people. IV Body Type proved high distribution each of Soeumin 29.4%(5) and Soyangin 29.4%(5). In case of main left side posture character of spine and limbs about I Body Type 72 persons with left scapular and ilium forward tilted pattern proved in the order high distribution iliac crest thigh and scapular high 70(97.2%), gluteal fold high and scapular abduction 69(95.8%), lumbar scoliosis 65(90.3%). Also, in case of right side posture character proved in the order high distribution deep gluteal fold 69(95.8%), umbilical deviation 68(94.4%). Incase of main left side posture character of spine and limbs about n Body Type 54 persons proved in the: order high distribution knee hyperextension 50(92.6%), shoulder deviation 49(90.7%) etc. Also, in case of right side posture character proved in the order high distribution pelvic deviation 53(98.1%), iliac crest thigh 52(96.3%), hip flexion and ankle inversion 51(94.4%) etc. In case of main left side posture character of spine and limbs about III Body Type 89 persons proved in the order high distribution shoulder deviation 87(97.8%), scapular abduction 86(96.6%), scapular high 85(95.5%) etc. And in case of right side posture character proved in the order high distribution pelvic deviation and iliac crest thigh 86(96.6%) etc. In case of main left side posture character of spine and limbs about IV Body Type 17 persons proved in the order high distribution pelvic deviation, lumbar sciliosis and lumbar lordosis increase 15(88.2%) etc. Also, in case of right side posture character proved in the order high distribution wrist dorsiflexion 16(94.1%), thickened achilles tendon etc.

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Selecting Minimized Input Features for Detecting Automatic Fall Detection Based on NEWFM (낙상 검출을 위한 NEWFM 기반의 최소의 특징입력 선택)

  • Shin, Dong-Kun;Lee, Sang-Hong;Lim, Joon-Shik
    • Journal of Internet Computing and Services
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    • v.10 no.3
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    • pp.17-25
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    • 2009
  • This paper presents a methodology for a fall detection using the feature extraction method based on the neural network with weighted fuzzy membership functions (NEWFM). The distributed non-overlap area measurement method selects the minimized number of input features by removing the worst input features one by one. Nineteen number of wavelet transformed coefficients captured by a triaxial accelerometer are selected as minimized features using the non-overlap area distribution measurement method. The proposed methodology shows that sensitivity, specificity, and accuracy are 95%, 97.25%, and 96.125%, respectively.

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Change of Stages and Related Factors for Wearing of Hearing Protection Device among Noisy Workplace-workers (소음작업장 근로자의 청력보호구 사용단계와 관련요인)

  • Kim, Young-Mi;Jeong, Ihn-Sook
    • Journal of Korean Academy of Nursing
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    • v.40 no.5
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    • pp.736-746
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    • 2010
  • Purpose: This study was done to identify the distribution and related factors for stage of change for wearing hearing protection devices (HPDs) by workers in environments with high noise. Predictors of Use of Hearing Protection Model and Trans-theoretical Model were tested. Methods: The participants were 755 workers from 20 noisy work places in Busan and Gyeongnam. Data were collected from January to April 2008 using self-administered questionnaires, and analyzed using multiple logistic regression. Results: There were significant differences in social mode (OR=1.35, 95% CI: 1.06-1.73) between precontemplation/contemplation and preparation stage, in males (OR=2.36, 95% CI: 1.24-4.51), workers with high school education or less (OR=1.39, 95% CI: 1.28-2.78), shift workers (OR=1.50, 95% CI: 1.02-2.21), workers who previously worked in noisy places (OR=1.39, 95% CI: 1.20-2.34), and workers who had previous hearing examinations (OR=1.89, 95% CI: 1.25-2.85), in the social model (OR=1.59, 95% CI: 1.42-1.78), and self-efficacy (OR=1.05, 95% CI: 1.02-1.08) between workers in preparation and action stages, in length of time working in noisy work places (OR=2.26, 95% CI: 1.17-4.39), social model (OR=1.66, 95% CI: 1.33-2.08), and perceived benefit (OR=0.95, 95% CI: 0.93-0.97) between action and maintenance stage. Conclusion: Social model was a common factor showing differences between two adjacent stages for wearing HPDs. The results provide data for developing programs to encourage workers to wear HPDs and application of these programs in work settings.

Distribution and Exposure Prevalence of Carbohydrate-based Food Intake among Obese Korean Adults Based on the Health Examinees (HEXA) Study (한국 성인 비만 집단의 탄수화물 급원 식품 섭취 분포 및 노출 위험도: 대규모 한국인유전체 역학 자료 활용)

  • Han, Yuri;Kwon, Sung-Ok;Lee, Sang-Ah
    • Korean Journal of Community Nutrition
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    • v.22 no.2
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    • pp.159-170
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    • 2017
  • Objectives: The purpose of this study was to estimate the distribution and exposure prevalence of total carbohydrate intake and the carbohydrate-based foods such as rice, noodles, sweet potatoes, sweet drinks, milk and fruits and to characterize intake patterns among obese Korean adults. Methods: Subjects included 137,363 adults aged 40 years or older who participated in a Health Examinees (HEXA) Study. Multiple regression analysis of data from Semi-Quantitative Food Frequency Questionnaire (SQFFQ) identified food sources of carbohydrates. Weight, height and waist circumstance (WC) were measured, and the body mass index (BMI) was calculated. Obesity was defined as $BMI{\geq}25kg/m^2$ and abdominal obesity as $WC{\geq}90cm$ and ${\geq}85cm$ for males and females, respectively. Results: Obese adults appeared to have a higher total carbohydrate intake in the univariate analysis but had eaten less after adjustment for general and lifestyle factors, compared to normal weight adults (OR 0.78, 95% CI 0.73-0.82 for general obesity; OR 0.79, 95% CI 0.74-0.85, for abdominal obesity; P trend < 0.0001, respectively). Based on advance analysis for the food sources of carbohydrates, obese subjects had lower intake of rice (OR 0.86, 95% CI 0.68 -1.09 for general obesity; OR 0.87, 95% CI 0.67-1.13, for abdominal obesity; P trend < 0.0001, respectively) and higher intake of noodles (OR 1.21, 95% CI 1.16-1.27 for general obesity; OR 1.25, 95% CI 1.19-1.32, for abdominal obesity; P trend < 0.0001 respectively). With regard to other food sources of carbohydrates such as milk and fruits, intake was lower among obese compared to normal weight subjects. Conclusions: In the Korean middle-aged and older obesity groups, the intake of carbohydrates and the related foods was lower than in normal weight subjects, except for noodles. We conclude that a higher intake of noodles may enhance weight-gain. Therefore, this study suggested that the guidelines should consider the types of carbohydrate sources and the amount consumed from foods in order to provide proper guidance with regard to control and prevent obesity among Korean adults.