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Long Term Outcome of In-Stent Stenosis after Stent Assisted Coil Embolization for Cerebral Aneurysm

  • Kim, Sung Jin;Kim, Young-Joon;Ko, Jung Ho
    • Journal of Korean Neurosurgical Society
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    • v.62 no.5
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    • pp.536-544
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    • 2019
  • Objective : The objective of this study was to evaluatelong-term radiologic prognosis and characteristics of in-stent stenosis (ISS) after stent assisted coiling (SAC) for cerebral aneurysm and analyze its risk factors. Methods : Radiological records of 362 cases of SAC during 10 years were retrospectively reviewed. Patients were included in this study if they had follow-up angiogram using catheter selected angiography at least twice. All subjected were followed up from 12 months to over 30 months. Of 120 patients, 123 aneurysms were enrolled. Patient data including age, sex, aneurysm size, neck size, procedural complication, kinds of stent, ISS associated symptom, ruptured state, location of ISS, degree of ISS, radiologic prognosis of ISS, follow-up period of time, and medical comorbidities such as hypertension, diabetes mellitus (DM), dyslipidemia, and smoking were collected.Statistical comparisons of group clinical characteristics were conducted for the total population. Results : Among 123 casesof aneurysm, 22 cases (17.9%) of ISS were revealed on follow-up angiography. Multiple stenting was performed in three cases and intra-procedural rupture occurred in two cases. Most cases were asymptomatic and symptomatic stenosis was identified in only one case. Sixteen cases were ruptured aneurysm. Mild stenosis was observed in 11 cases. Moderate stenosis was found in eight cases and severe stenosis was identified in three cases. Mean timing of identification of ISS was 8.90 months. The most common type was proximal type. Most cases were improved or not changed on follow-up angiography. Only one case was aggravated from mild stenosis to occlusion of parent artery. Mean follow-up period was 44.3 months. We compared risk factors and characteristic between ISS group and non-ISS group using univariate analysis. Multiple stenting was performed for three cases (13.6%) of the ISS group and four cases (4.0%) of the non-ISS group, showing no statistical difference between the two groups (p=0.108). Additionally, the proportion of patients who had more than two risk factors among four medical risk factors (hypertension, DM, dyslipidemia, and smoking) was higher in the ISS group than that in the non-ISS group, the difference between the two was not statistically significant either (31.8% vs. 12.9%, p=0.05). Conclusion : Clinical course and long-term prognosis of ISS might be benign. Most cases of ISS could be improved or not aggravated. Control of medical co-morbidity might be important. To the best of our knowledge, our study had more cases with longer follow-up period of time than other reports.

Changes in the glucose and insulin responses according to high-protein snacks for diabetic patients

  • Yang, Junyoung;Park, Hae Jin;Hwang, Wonsun;Kim, Tae Ho;Kim, Hyeonmok;Oh, Jieun;Cho, Mi Sook
    • Nutrition Research and Practice
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    • v.15 no.1
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    • pp.54-65
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    • 2021
  • BACKGROUND/OBJECTIVES: This study aimed to develop healthy, appetizing high-protein snacks with enhanced isolated soy protein for diabetic patients and determine the blood glucose and insulin response after being consumed by these patients. MATERIALS/METHODS: Thirty adult patients aged between 30 and 75 years, with a ≤ 10-year history of type 2 diabetes and hemoglobin A1c of < 7.5%, were enrolled in this study. They made 3 clinical visits at one-week intervals. The control group consumed 50 g carbohydrates (white bread), whereas the test groups consumed high-protein grain (HP_G) or high-protein chocolate (HP_C) after an 8-hrs fast. Blood (2 ㎤) was drawn at 15, 30, 45, 60, 90, and 120 min before and after consumption to analyze the blood glucose and insulin concentrations. RESULTS: Compared to the commercial snacks, the developed high-protein snacks had below-average calorie, carbohydrate, and fat content and a 2.5-fold higher protein content. In diabetic patients who consumed these snacks, the postprandial blood glucose increased between 15 min and 2 h after consumption, which was significantly slower than the time taken for the blood glucose to increase in the patients who consumed the control food product (P < 0.001). Insulin secretion was significantly lower at 45 min after consumption (P < 0.05), showing that the high-protein snacks did not increase the blood glucose levels rapidly. The incremental area under the curve (iAUC), which indicated the degree of blood sugar and insulin elevation after food intake, was higher in the control group than the groups given the 2 developed snacks (P < 0.001), and there was no significant difference in insulin secretion. CONCLUSIONS: The results of the postprandial blood glucose and insulin response suggest that high-protein snacks are potential convenient sources of high-quality protein and serve as a healthier alternative for patients with type 2 diabetes, who may have limited snack product choices. Such snacks may also provide balanced nutrition to pre-diabetic and obese individuals.

A Study on the Time-Sectional Analysis of Apartment Housing related research in Korea (국내 아파트 관련 연구의 연구주제 시계열 분석)

  • Kim, Tae-Sok;Park, Jong-Mo;Park, Eu-Gene;Han, Dong-Suk
    • Journal of the Architectural Institute of Korea Planning & Design
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    • v.34 no.3
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    • pp.45-52
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    • 2018
  • Currently, apartments have become an important research subject for the overall area of politics, economics, and culture as well as urban architectural study. However, there are few analyses of the research trends related to the current interest in the apartment research and prediction of the future changes of an apartment in politics and industry. In this study, the research information related to the apartment has classified, and the changes in the research trends have analyzed. Based on the classified data, the first thesis and dissertation related to the apartment and changes of academic notation have discovered. In addition, future interests and future research directions through Frequency of Appearance, Degree Centrality Analysis, and Betweenness Centrality Analysis of author keywords were predicted. As a result of the analysis, 'Space,' 'Residential Mobility' and 'Apartment Complex' studies were found to be important research topics throughout the entire period. 'Han Gang Apartment,' 'Small Size Apartment,' 'Civic Apartments,' 'Jamsil,' and 'Child' were newly interested topics until 70's era. '(Super) High-rise Apartment,' 'Perception,' 'Jugong Apartment,' 'Housing Environment,' 'Housewife,' 'Apartment Layout,' and 'Busan' were newly interested topics during the 80's and 90's era. 'Apartment Price,' 'Energy,' 'Remodeling,' 'Noise,' 'Resident Satisfaction,' 'Community,' and 'Apartment Lotting-out' were newly interested topics after the year 2000. New concerns for last decade are found to be 'Super High-rise Apartment', 'Remodeling', 'Indoor'(2007), 'Apartment Reconstruction Project', 'Brand', 'AHP', 'Housing Environment'(2008), 'Ventilation'(2009), 'Apartment Lotting-out'(2010), 'Economic Assessment'(2011), 'Cost'(2012), 'Green Building', 'Apartment Sales', 'Law', 'Society'(2013), 'Floor Impact Noise', 'Seoul'(2014), 'Noise'(2015), 'Hedonic Model'(2016). In addition, following research topics are expected to be active in the future: In maturity stage of the research development is going to be 'Apartment Price', 'Space', 'Management of Apartment Housing'; the hedonic model, which is research growth and development stage, is going to be '(Floor Impact) Noise', 'Community', 'Energy.

A study on difference of supervision perception between supervisors and supervisees (수퍼바이저와 수퍼바이지 간의 수퍼비전(Supervision) 인식 차이)

  • Kim, Do-Muk
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.22 no.6
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    • pp.357-374
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    • 2021
  • This study examined the difference in perception of supervision between supervisors and supervisees of community welfare centers. The survey subjects were 100 social workers working at social welfare centers in Seoul, Busan, and Incheon. The survey subjects were 62% women and 38% men in their 30s. Approximately 98% of supervisors and 88% of supervisees had a college degree or higher. Regarding the total working period of social welfare institutions, 82% of supervisors and 12% of supervisees had five years or more experience. Regarding the perception of the overall supervision between the supervisors and supervisees, the supervisors and supervisees reported a score of 3.79 and 3.46, respectively. In the perception of supervision according to function, in the case of administrative supervision recognition, the supervisors and supervisees reported a score of 3.78 and 3.43, respectively, and in the educational supervision recognition, the supervisors and supervisees reported a score of 3.65 and 3.29, respectively. Regarding supportive supervision perception, the supervisors and supervisees reported a score of 3.94 and 3.67, respectively. As shown in the above results, the difference in the perception of supervisor and supervisee's supervision by function shows that the supervisor's supervision by all functions is higher than that of the supervisee. As a result, such supervisions are relatively low among supervisees who are provided with supervisions than supervisions that are perceived as being provided by supervisors.

Development and analysis of assessment model of a village-level rural living services for response to rural depopulation (농촌 과소화 대응을 위한 마을 단위 농촌생활서비스 평가 모델의 개발 및 분석)

  • Hong, Sangwon;Bae, Seung-Jong;Kim, Dong-Hyeon;Kim, Soo-Jin;Kim, Jungtae;Jang, Taeil
    • Journal of Korean Society of Rural Planning
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    • v.27 no.1
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    • pp.57-70
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    • 2021
  • The degree of benefits of living services related to the quality of life can solve the depopulation problem, and it is necessary to be able to quantitatively analyze problems related to the quality of life in rural areas in order to cope with the rural depopulation. The purpose of this study was to develop the assessment model of a village-level rural living service that reflects the regional characteristics of rural villages to evaluate the level of rural living services for response rural depopulation. Based on the review of previous related studies, the evaluation index was composed of seven sectors of education, health, welfare, culture, environment, safety, and convenience, and the assessment model of a rural living service was established. This model was evaluated through a sample survey of 90 villages in Nonsan-si, Seongju-gun, and Pyeongchang-gun. As a result of the rural life services evaluation by Si and Gun, Seongju-gun, which is affected by nearby large cities, has the largest variation by village level and is assessed at a lower level overall than other Si and Gun. As a result of the rural life services evaluation by 7 sectors, in the case of health and welfare, low scores were shown in the assessment model, but the level of residents' satisfaction was mid-level. In particular, in the case of Seongju-gun, there were significant differences in the assessment model and the survey results of the level of residents' satisfaction in the health and welfare sectors due to the influence of nearby large cities. As a result of analyzing the number of villages corresponding to the top 30% and the bottom 30% of the evaluation results for each sector, it was analyzed that the villages with the highest evaluation results in Pyeongchang-gun in both the assessment model and the level of residents' satisfaction. It implies that quantitative analysis of data based index and accessibility as well as level satisfaction of residents are necessary.

The Design and implementation of parallel processing system using the $Nios^{(R)}$ II embedded processor ($Nios^{(R)}$ II 임베디드 프로세서를 사용한 병렬처리 시스템의 설계 및 구현)

  • Lee, Si-Hyun
    • Journal of the Korea Society of Computer and Information
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    • v.14 no.11
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    • pp.97-103
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    • 2009
  • In this thesis, we discuss the implementation of parallel processing system which is able to get a high degree of efficiency(size, cost, performance and flexibility) by using $Nios^{(R)}$ II(32bit RISC(Reduced Instruction Set Computer) processor) embedded processor in DE2-$70^{(R)}$ reference board. The designed Parallel processing system is master-slave, shared memory and MIMD(Mu1tiple Instruction-Multiple Data stream) architecture with 4-processor. For performance test of system, N-point FFT is used. The result is represented speed-up as follow; in the case of using 2-processor(core), speed-up is shown as average 1.8 times as 1-processor's. When 4-processor, the speed-up is shown as average 2.4 times as it's.

The Change of Traffic Accident Risk Degree by Driving Stress Coping Patterns (운전스트레스 대처방식에 따른 교통사고 위험의 변화)

  • Soon yeol Lee ;Soon chul Lee
    • Korean Journal of Culture and Social Issue
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    • v.15 no.3
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    • pp.431-446
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    • 2009
  • This study was intended to validate and develop the driving stress coping behavior scale. In a preliminary investigation, literature studies on the driving stress and open questionnaire were administered and examined in four regions in Korea. As a result, 64 items driving stress questionnaire were developed. In the study, this Driving Stress Coping Behavior Scale(DS-CBS) was examined to 372 drivers located seven regions in Korea. The factors analysis revealed 2 meaningful factors[(Good Coping: GC), (Bad Coping: BC) with 24 items. When internal consistency for each 2 factor was calculated, all sub-scale revealed a satisfactory level of Cronbach's α. Also, correlations with Driver Coping Questionnaire(DCQ) and risk driving behaviors(speed driving, drunken driving, traffic violation, offence accident, defence accident) supported consistently validity of the Driving Stress Coping Behavior Scale(DS-CBS). Also, We investigated the influences of 'Good Coping', 'Bad Coping' consisting of driving stress coping behavior, on traffic accidents risk. As a result, 'Good Coping' and 'Bad Coping' influenced traffic accidents risk. 'Good Coping' had decreased effects, the other side 'Bad Coping' had increased effects on traffic accidents risk(TARI).

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Enzymatic preparation and antioxidant activities of protein hydrolysates from defatted egg yolk (탈지난황을 이용한 단백가수분해물 제조 및 항산화 활성 평가)

  • Go-Eun Ko;Na-Yeong Kwak;Ha-Eun Nam;Su-Jin Seo;Syng-Ook Lee
    • Food Science and Preservation
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    • v.31 no.3
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    • pp.444-451
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    • 2024
  • This study aimed to investigate the characteristics of protein hydrolysates derived from defatted egg yolk using various proteolytic enzymes and compare the antioxidant activity of the resulting hydrolysates. The defatted egg yolk powder was subjected to enzymatic hydrolysis using four different proteases (alcalase, bromelain, flavourzyme and neutrase), and the resulting hydrolysates were evaluated for their antioxidant properties. Through analysis of available amino group contents and sodium dodecyl sulfate-polyacrylamide gel electrophoresis, it was observed that the defatted egg yolk powder treated with alcalase, flavourzyme, and neutrase for 12 h exhibited a high degree of hydrolysis value. Based on the RC50 values obtained from two different antioxidant analyses, all hydrolysates showed comparable antioxidant activity, except for the alcalase hydrolysate, which demonstrated notably higher scavenging activity against hydrogen peroxide than the other hydrolysates. These findings suggest the potential of protein hydrolysates from defatted egg yolk, a by-product of lecithin extraction, as natural antioxidants.

Morphological Variation of Cultivated Types of Perilla Crop and Their Weedy Types in East and Southeast Asia (동아시아 및 동남아시아에서 수집한 들깨, 차조기 작물과 잡초형 계통들의 형태적 변이)

  • Kim, Jin-Ah;Sa, Kyu Jin;Choi, Seung Hun;Lee, Ju Kyong
    • KOREAN JOURNAL OF CROP SCIENCE
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    • v.58 no.4
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    • pp.408-415
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    • 2013
  • To better understand the morphological variation of the Perilla crop and their weedy types in East and Southeast Asia, we studied the morphological variation of 90 accessions by examining 10 morphological characteristics, such as flowering time, seed size, seed hardness, seed color, color of surface leaf, color of reverse side leaf etc. As a result, morphological variation determined that between cultivated var. frutescens and var. crispa, and between cultivated var. frutescens and its weedy type showed significant morphological differences in terms of seed size and seed hardness, whenever cultivated var. crispa and its weedy type could not showed significant differences in most morphological characters. In PCAs (principal component analysis), among 10 morphological characteristics, flower color (QL6), color of surface leaf (QL3), seed size (QN2), seed hardness (QL1), seed color (QL2), stem color (QL7), and color of reverse side leaf (QL4) contributed in negative direction on the first axis, while flowering time (QN1), leaf shape (QL5), and degree of pubescence (QL8) contributed in positive direction on the first axis. Among these morphological characters, particularly flower color (QL6), color of surface leaf (QL3), seed size (QN2), seed hardness (QL1), and degree of pubescence (QL8) were useful characters for discrimination between cultivated var. frutescens and weedy var. crispa, and between cultivated var. frutescens and its weedy type. However, most accession of cultivated and weedy types of var. crispa was not clearly discriminated by PCA analyses. Although the wild ancestral species of var. frutescens and of var. crispa are still unknown in East and Southeast Asia, the weedy types of Perilla crop may be the key taxon for our understanding of the origin of cultivated types of var. frutescens and var. crispa.

Effects of Self Care Program on Hypertensive Control in Hypertensive Patient (고혈압환자에게 적용한 자가관리프로그램 중재 효과)

  • Kim, Ok-Ran
    • Research in Community and Public Health Nursing
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    • v.14 no.4
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    • pp.568-578
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    • 2003
  • This study was conducted to estimate the effects of self-care program on knowledge and symptoms related hypertension self-care and physiological index in essential hypertensive patients aged between 35-74 year. The subjects for the experiment group and the control group of this study were 70 men and women selected through random sampling from adults at Sangju Red Cross Hospital in Gyeongsanbuk-do, and the experiment was carried out during the period from the 15th of September to the 30th of April in 2002. This study measured systolic and diastolic blood pressure (SBP, DBP, the mean value of the two measures) and total cholesterol (TC) and surveyed the subjects' diet and life style in relation to hypertension using a self-report questionnaire. In order to study the significance of the effects of self-care program, the author carried out t-test, paired t-test, ANCOVA, chi-square analysis and effectiveness index (EI) analysis. Results of the study are as follows: The experiment group got higher mean scores than the control group in the degree of low sodium intake and the degree of high calcium and high potassium intake, and the difference was statistically significant(P<0.05). The effectiveness index of the self-care program in smoking was 0.797 at the 1st posttest and 0.601 at the 2nd posttest, and in physical activities 0.600 at the 1st posttest and 0.849 at the 2nd posttest. The rate of regular antihypertensive drugs intake of the experimental group was higher than that of the control group. and the effectiveness index of the self-care program was 0.715. The mean score of the systolic blood pressure of the experimental group was lower than that of the control group, and the difference was statistically significant(P<0.05). In conclusion, these findings support usefulness of self-care programs in reducing systolic blood pressure and in promoting self-care related to diet and life style for treating and preventing hypertension.

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