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Continuous renal replacement therapy in neonates weighing less than 3 kg

  • Sohn, Young-Bae;Paik, Kyung-Hoon;Cho, Hee-Yeon;Kim, Su-Jin;Park, Sung-Won;Kim, Eun-Sun;Chang, Yun-Sil;Park, Won-Soon;Choi, Yoon-Ho;Jin, Dong-Kyu
    • Clinical and Experimental Pediatrics
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    • v.55 no.8
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    • pp.286-292
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    • 2012
  • Purpose: Continuous renal replacement therapy (CRRT) is becoming the treatment of choice for supporting critically ill pediatric patients. However, a few studies present have reported CRRT use and outcome in neonates weighing less than 3 kg. The aim of this study is to describe the clinical application, outcome, and complications of CRRT in small neonates. Methods: A retrospective review was performed in 8 neonatal patients who underwent at least 24 hours of pumped venovenous CRRT at the Samsung Medical Center in Seoul, Korea, between March 2007 and July 2010. Data, including demographic characteristics, diagnosis, vital signs, medications, laboratory, and CRRT parameters were recorded. Results: The data of 8 patients were analyzed. At the initiation of CRRT, the median age was 5 days (corrected age, $38^{+2}$ weeks to 23 days), and the median body weight was 2.73 kg (range, 2.60 to 2.98 kg). Sixty-two patient-days of therapy were reviewed; the median time for CRRT in each patient was 7.8 days (range, 1 to 37 days). Adverse events included electrolyte disturbances, catheter-related complications, and CRRT-related hypotension. The mean circuit functional survival was $13.9{\pm}8.6$ hours. Overall, 4 patients (50%) survived; the other 4 patients, who developed multiorgan dysfunction syndrome, died. Conclusion: The complications of CRRT in newborns are relatively high. However, the results of this study suggest that venovenous CRRT is feasible and effective in neonates weighing less than 3 kg under elaborate supportive care. Furthermore, for using potential benefit of CRRT in neonates, efforts are required for prolonging filter survival.

A Study on the Efficient Algorithm for Converting Range Matching Rules into TCAM Entries in the Packet Filtering System (패킷 필터링 시스템에서 범위 규칙의 효율적 TCAM 엔트리 변환 알고리즘 연구)

  • Kim, Yong-Kwon;Cho, Hyun-Mook;Choe, Jin-Kyu;Lee, Kyou-Ho;Ki, Jang-Geun
    • Journal of IKEEE
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    • v.9 no.1 s.16
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    • pp.19-30
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    • 2005
  • Packet classification is defined as the action to match the packet with a set of predefined rules. One of classification is to use Ternary Content Addressable Memory hardware search engine that has faster than other algorithmic methods. However, TCAM has some limitations. One of them is that TCAM can not perform range matching efficiently. A range has to be expanded into prefixes to fit the boundary. In general, the number of expansion could be up to 2w-2, where w is the width of the field. For example, if two range fields with 16 bits are used, there could be up to $30\;{\times}\;30\;=\;900$ expansions for a single rule. In this paper, we describe the novel algorithm for converting range matching rules into TCAM entry efficiently. The number of maximum entry is 2w-4 when using the algorithm. Furthermore, it has also benefit about the negation range. In the result of experimentation, the new scheme practically reduces 14 percent in case that searched fields are source port and destination port number.

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Studies on the Submerged Culture of Lentinula edodes Mycelia in Brewer's Yeast Extract Medium (맥주효모 추출물을 이용한 표고버섯 균사체의 심부배양에 관한 연구)

  • Lee, Jae-Yun;An, Won-Gun;Lee, Jae-Dong
    • The Korean Journal of Mycology
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    • v.22 no.3
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    • pp.266-275
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    • 1994
  • Brewer's yeast extract can be used as a good substrate for the culture of Lentinula edodes Mycelia(LEM). We found that it was better to filter the extract through three kinds of sieves and then to heat for hydrolysis and concentration at $90^{\circ}C$ prior to use. Also the maximum condition for the growth of LEM was investigated. We found that addition of inorganic salts such as calcium enhanced the growth of LEM. On the other hand, addition of carbon and nitrogen sources to the medium did not affect, and even inhibited under certain conditions, the growth of LEM. The maximum temperature for the growth of LEM was around $25^{\circ}C$. Also, it grows better when agitated by shaking at 100 rpm for airration. The appropriate concentration of the extract to use was 10%. Under these conditions, LEM could reach to the confluency after cultivation of 12 days. Our extract formula seems better than other available media for LEM growth, producing higher crude protein content and better taste.

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Effects of VFS(Vegetative Filter System) for Reducing Non-Point Source Pollution (초생대 밭경지 비점오염저감 효과)

  • Choi, Kyung-Sook;Jang, Jeong-Ryeol
    • Proceedings of the Korea Water Resources Association Conference
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    • 2012.05a
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    • pp.435-435
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    • 2012
  • 농경지 중에서 밭은 논보다 농약 비료 사용률이 매우 높기 때문에 논에 비해 비점오염물질 배출량이 훨씬 심각한 것으로 조사되고 있어 밭경지 비점오염저감기법 개발 및 체계적인 제어대책 수립이 무엇보다도 절실하다. 현재 선진국을 중심으로 다양하게 제시되고 있는 밭경지 비점오염 제어기법들 중 초생대에 대한 성공적 연구사례 및 적용사례에 대한 자료가 상당히 많이 제시되고 있으나, 우리나라의 경우 초생대를 적용한 밭경지 비점오염저감에 대한 기술개발 및 체계적인 연구가 아직 미비한 실정이다. 따라서 본 연구는 초생대의 현장설치 및 모니터링을 통해 초생대의 비점오염부하 저감효과에 대한 기초조사를 실시하고 우리나라 밭경지에서의 적용가능성을 알아보고자 한다. 초생대 현장 실험을 위한 시험포는 경상북도 군위군 효령면에 위치한 경북대 농생대 부속농장 밭경지 $1,500m^2$ (455평)를 선정하였다. 시험포는 1개의 대조구와 6개의 처리구로 구성하였으며, 각 시험구의 크기는 길이 12m ${\times}$ 폭 4m (초생대 길이 2m ${\times}$ 폭 4m 포함)로 하였다. 초생대 조성을 위한 초종선정은 초생대 조성이 용이하고 관리효율성이 높은 초종으로서 손쉽게 구할 수 있고, 우리나라 기후와 토양특성에 적합하며 초생대 기능에 부합한 것으로 선정하였다. 초생대 시험포장에 재배할 작물은 우리나라 대표 밭작물인 콩으로 선정하였으며, 작물재배를 위한 퇴비, 비료, 제초제 등은 농촌진흥청에서 제시한 표준재배법에 준하여 시용하였다. 초생대 비점오염저감효과를 평가하기 위해서 시험포장에 플륨, 수위계, 강우계 등으로 구성된 모니터링시스템을 설치하였으며, 플륨의 수위-유량 캘리브레이션을 실시하였다. 실험을 위해 2회의 인공강우와 1회의 자연강우에 대한 모니터링을 실시하였다. 그 결과 초생대 조성이 유출률에 상당한 영향을 미치는 것으로 조사되었다. 인공강우의 경우 초생대 설치에 따라 유출률의 범위가 14.5~95.8% 정도로 감소되는 현상을 보였으며, 자연강우에서도 6.1~11.3% 정도의 유출률 감소를 보였다. 초생대 시험구별 유출률에 차이를 나타낸 이유는 현장실험시의 시험구별 지면조건과 초생대 초종별 특성(초장, 경경, 밀도 등)의 차이에 기인한 결과로 사료되었다. 비점오염저감효과 측면에서는 기존 밭농사 방식을 그대로 채택한 대조구에 비해 초생대 시험구에서 TS의 경우 15.6~90.3%, T-P의 경우 49.9~87.8%, T-N의 경우 6.7~91.1%의 저감율을 각각 나타내었다. 이러한 결과들을 통해 초생대 기법이 우리나라 밭경지 비점오염부하를 저감시키는데 유용하게 활용될 수 있을 것으로 판단된다.

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A Study on the Emission and Dispersion of Particulate Matter from a Cement Plant (한 시멘트공장의 분진발생과 대기확산에 관한 조사연구)

  • Chang, Man-Ik;Chung, Yong;Kwon, Sook-Pyo
    • Journal of Preventive Medicine and Public Health
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    • v.16 no.1
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    • pp.67-77
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    • 1983
  • To investigate the an air pollution by particulate matter and its dispersion, a cement plant produceing portland cement 600,000 ton/year and its vicinity were surveyed from Obtober, 1980 to April, 1983. The survey was mainly focused on main stack emmission rate of the cement plant and particle size distribution in the dust, dustfall and total suspended particulate concentration in the area by month and distance from the stack. The results of the study were as follows; 1. The main stack emission rate was surveyed before and after the spray tower was additionally installed to the original E.P bag filter. Before the spray tower installed, the main stack emission rate was higher ($0.64g/Nm^3$) than the emission standard of Korean Environmental Preservation Law's ($0.59g/Nm^3$, amended to $0.4g/Nm^3$ on April 1983), but after the spray tower was installed, its main stack emission rate was markedly decreased to the standard ($0.43g/Nm^3$). 2. $2{\sim}3{\mu}m$ of the particle size was the largest portion (20.8%) of the dust particulate from the main stack and 50% of the frequency distribution was $1.5{\mu}m$ of the size. Most particle size was below $10{\mu}m$. 3. The spray tower reduced the dustfall to $37.81{\sim}9.76\;ton/km^2/month$ while dustfall appeared at $45.29-15.45ton/km^2/month$, in the vicinity of plant before spray tower installed 4. Mean concentrations of total suspended particulate for 24 hours of the various stations were determined in $20.6-200.0{\mu}g/m^3$, 3 stations of tham were higher than the value of Harry and William's arthmetic average standard $130{\mu}g/m^3$. 5. Linear regression between dustfall [X] and total suspended particulate[Y] concentration was an equation, Y=4.024X+11.479.[r=0.91] 6. During the whole seasons in the opposite area 100m apart from the omission source the prevailing wind direction was with estimated more than $30ton/km^2/month$, and the concentration of total suspended particulate for 24 hours averaging time was more than $140{\mu}g/m^3$ in the same area and direction. 7. Assuming the wind direction were constant through the day dustfalls for a day were estimated at $13.40ton/km^2/day,\;10.79ton/km^2/day$ and $4.55ton/km^2/day$ at various distances of 100m, 500m and 1,500m from the emission source respectively. 8. In the simutalion of dustfall and suspended dust by area, Gaussian dispersion model modified by size distribution of particulate matter was not applicated since the emission of dust were from multi sources other them stack. From the above results, it could be applied that the dispersion of dust from the cement plant is estimated and regulated for the purpose of environmental protection.

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Development of Urban Wildlife Detection and Analysis Methodology Based on Camera Trapping Technique and YOLO-X Algorithm (카메라 트래핑 기법과 YOLO-X 알고리즘 기반의 도시 야생동물 탐지 및 분석방법론 개발)

  • Kim, Kyeong-Tae;Lee, Hyun-Jung;Jeon, Seung-Wook;Song, Won-Kyong;Kim, Whee-Moon
    • Journal of the Korean Society of Environmental Restoration Technology
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    • v.26 no.4
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    • pp.17-34
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    • 2023
  • Camera trapping has been used as a non-invasive survey method that minimizes anthropogenic disturbance to ecosystems. Nevertheless, it is labor-intensive and time-consuming, requiring researchers to quantify species and populations. In this study, we aimed to improve the preprocessing of camera trapping data by utilizing an object detection algorithm. Wildlife monitoring using unmanned sensor cameras was conducted in a forested urban forest and a green space on a university campus in Cheonan City, Chungcheongnam-do, Korea. The collected camera trapping data were classified by a researcher to identify the occurrence of species. The data was then used to test the performance of the YOLO-X object detection algorithm for wildlife detection. The camera trapping resulted in 10,500 images of the urban forest and 51,974 images of green spaces on campus. Out of the total 62,474 images, 52,993 images (84.82%) were found to be false positives, while 9,481 images (15.18%) were found to contain wildlife. As a result of wildlife monitoring, 19 species of birds, 5 species of mammals, and 1 species of reptile were observed within the study area. In addition, there were statistically significant differences in the frequency of occurrence of the following species according to the type of urban greenery: Parus varius(t = -3.035, p < 0.01), Parus major(t = 2.112, p < 0.05), Passer montanus(t = 2.112, p < 0.05), Paradoxornis webbianus(t = 2.112, p < 0.05), Turdus hortulorum(t = -4.026, p < 0.001), and Sitta europaea(t = -2.189, p < 0.05). The detection performance of the YOLO-X model for wildlife occurrence was analyzed, and it successfully classified 94.2% of the camera trapping data. In particular, the number of true positive predictions was 7,809 images and the number of false negative predictions was 51,044 images. In this study, the object detection algorithm YOLO-X model was used to detect the presence of wildlife in the camera trapping data. In this study, the YOLO-X model was used with a filter activated to detect 10 specific animal taxa out of the 80 classes trained on the COCO dataset, without any additional training. In future studies, it is necessary to create and apply training data for key occurrence species to make the model suitable for wildlife monitoring.

Exposure Assessment of Dust, Ultra Fine Dust(Particulate Matter 2.5, PM2.5) and Black Carbon among Aircraft Cabin Cleaners (항공기 기내 청소노동자의 분진, 초미세먼지(PM2.5) 및 블랙카본 노출수준 평가)

  • Hyunhee Park;Sedong Kim;Sungho Kim;Seung-Hyun Park
    • Journal of Korean Society of Occupational and Environmental Hygiene
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    • v.33 no.2
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    • pp.171-187
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    • 2023
  • Objectives: Aircraft cabin cleaning work is characterized by being performed within a limited time in a narrow and enclosed space. The objective of this study was to evaluate the exposure levels to dust, ultra fine dust(PM2.5) and black carbon(BC) among aircraft cabin cleaners. Methods: Active personal air sampling for respirable dust(n=73) and BC(n=47) was conducted during quick transit cleaning(cabin general and vacuum-specific) and seat cover replacement and total dust and PM2.5 were area-air-sampled as well. Also, size distribution of particle was identified with the cleaning workers targeted. Dusts were collected with PVC filters using gravimetric analysis. The concentration of PM2.5 and the particle size distribution were measured with real-time direct reading portable equipment using light scattering analysis. The concentration of BC was measured by aethalometer(filter-based real-time light absorption analysis instrument). Results: The geometric mean of respirable dust was the highest at vacuum cleaning as 74.4 ㎍/m3, following by replacing seat covers as 49.3 ㎍/m3 and cabin general cleaning as 47.8 ㎍/m3 . The arithmetic mean of PM2.5 was 4.83 ~ 9.89 ㎍/m3 inside the cabin, and 28.5~44.5 ㎍/m3 outside the cabin(from bus and outdoor waiting space). From size distribution, PM2.5/PM10 ratio was 0.54 at quick transit cleaning and 0.41 at replacing seat covers. The average concentration of BC was 2~7 ㎍/m3, showing a high correlation with the PM2.5 concentration. Conclusions: The hazards concentration levels of aircraft cabin cleaners were very similar to those of roadside outdoor workers. As the main source of pollution is estimated to be diesel vehicles operating at airports, and it is necessary to replace older vehicles, strengthen pollutant emission control regulations, and introduce electric vehicles. In addition, it is necessary to provide as part of airport-inftastructure a stable standby waiting space for aircraft cabin cleaners and introduce a systematic safety and health management system for all workers in the aviation industry.

Accurate Measurement of Agatston Score Using kVp-Independent Reconstruction Algorithm for Ultra-High-Pitch Sn150 kVp CT

  • Xi Hu;Xinwei Tao;Yueqiao Zhang;Zhongfeng Niu;Yong Zhang;Thomas Allmendinger;Yu Kuang;Bin Chen
    • Korean Journal of Radiology
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    • v.22 no.11
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    • pp.1777-1785
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    • 2021
  • Objective: To investigate the accuracy of the Agatston score obtained with the ultra-high-pitch (UHP) acquisition mode using tin-filter spectral shaping (Sn150 kVp) and a kVp-independent reconstruction algorithm to reduce the radiation dose. Materials and Methods: This prospective study included 114 patients (mean ± standard deviation, 60.3 ± 9.8 years; 74 male) who underwent a standard 120 kVp scan and an additional UHP Sn150 kVp scan for coronary artery calcification scoring (CACS). These two datasets were reconstructed using a standard reconstruction algorithm (120 kVp + Qr36d, protocol A; Sn150 kVp + Qr36d, protocol B). In addition, the Sn150 kVp dataset was reconstructed using a kVp-independent reconstruction algorithm (Sn150 kVp + Sa36d, protocol C). The Agatston scores for protocols A and B, as well as protocols A and C, were compared. The agreement between the scores was assessed using the intraclass correlation coefficient (ICC) and the Bland-Altman plot. The radiation doses for the 120 kVp and UHP Sn150 kVp acquisition modes were also compared. Results: No significant difference was observed in the Agatston score for protocols A (median, 63.05; interquartile range [IQR], 0-232.28) and C (median, 60.25; IQR, 0-195.20) (p = 0.060). The mean difference in the Agatston score for protocols A and C was relatively small (-7.82) and with the limits of agreement from -65.20 to 49.56 (ICC = 0.997). The Agatston score for protocol B (median, 34.85; IQR, 0-120.73) was significantly underestimated compared with that for protocol A (p < 0.001). The UHP Sn150 kVp mode facilitated an effective radiation dose reduction by approximately 30% (0.58 vs. 0.82 mSv, p < 0.001) from that associated with the standard 120 kVp mode. Conclusion: The Agatston scores for CACS with the UHP Sn150 kVp mode with a kVp-independent reconstruction algorithm and the standard 120 kVp demonstrated excellent agreement with a small mean difference and narrow agreement limits. The UHP Sn150 kVp mode allowed a significant reduction in the radiation dose.

Interspecies Nuclear Transfer using Bovine Oocytes Cytoplasm and Somatic Cell Nuclei from Bovine, Porcine, Mouse and Human (소, 돼지, 생쥐, 사람의 체세포와 소 난자를 이용한 이종간 핵 이식)

  • 박세영;김은영;이영재;윤지연;길광수;김선균;이창현;정길생;박세필
    • Korean Journal of Animal Reproduction
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    • v.26 no.3
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    • pp.235-243
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    • 2002
  • This study was designed to examine the ability of the bovine (MII) oocytes cytoplasm to support several mitotic cell cycles under the direction of differentiated somatic cell nuclei of bovine, porcine, mouse and human. Bovine GV oocytes were matured in TCM-199 supplemented with 10% FBS. At 20h after IVM, recipient oocytes were stained with 5 $\mu\textrm{g}$/$m\ell$ Hoechst and their 1st polar body (PB) and MII plate were removed by enucleation micropipette under UV filter. Ear skin samples were obtained by biopsy from an adult bovine, porcine, mouse and human and cultured in 10% FBS added DMEM. Individual fibroblast was anlaysed chromosome number to confirm the specificity of species. Nuclear transferred (NT) units were produced by electrofusion of enucleated bovine oocytes with individual fibroblast. The reconstructed embryos were activated in 5 $\mu$M ionomycin for 5 min followed by 1.9 mM 6-dimethylaminopurine (DMAP) in CR1aa for 3 h. And cleaved NT embryos were cultured in CR1aa medium containing 10% FBS on monolayer of bovine cumulus cell for 8 days. Also NT embryo of 4~8 cell stage was analysed chromosome number to confirm the origin of nuclear transferred somatic cell. The rates of fusion between bovine recipient oocytes and bovine, porcine, mouse and human somatic cells were 70.2%, 70.2%, 72.4% and 63.0%, respectively. Also, their cleavage rates were 60.6%, 63.7%, 54.1% and 62.7%, respectively, there were no differences among them. in vitro development rates into morula and blastocyst were 17.5% and 4.3% in NT embryos from bovine and human fibroblasts, respectively. But NT embryos from porcine and mouse fibroblasts were blocked at 16~32-cell stage. The chromosome number in NT embryos from individual fibroblast was the same as chromosome number of individual species. These results show that bovine MII oocytes cytoplasm has the ability to support several mitotic cell cycles directed by newly introduced nuclear DNA.

Study on Sound Production and Phonotaxis of Some Fishes and Crabs (몇가지 어류 및 갑각류의 발음과 주음성에 관한 연구)

  • 김상한
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.14 no.1
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    • pp.15-36
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    • 1978
  • Underwater sounds of some fishes and crabs were analyzed in the laboratory. The behavioral responses to the playback sounds of their feeding and croaking sound were investigated. The samples used in the experiment were as follows: Nibea albiflora, seriola quinqueradiata, Navodon modestus, Fugu xanthopterus, chrysophrys major, Scylla serrata, Telmessus acutidens, Charybdis japonica, and Portunus trituberculatus. The feeding and croaking sounds of the samples were recorded by a tape recorder through a hydrophone in an anechoic aquarium. The sound intensity level was measured by means of a sound level meter at an anechoic chamber. The frequency, intensity and wave form of various sounds were analyzed with an analyzing system consisting of a 1/3 octave filter set, a high speed level recorder, an amplifier, an octave band analyzer and an oscilloscope. The most successful recording was edited into a sequence of sound track which repeats sound emitting for 5 to 7 seconds after pausing for 5 to 7 seconds. The sequence was then reproduced into an anechoic aquarium through the under water speaker. The experimental anechoic aquarium used for the sample fishes was divided into the four sections with any three screens selected from 40$\times$40mm, 60$\times$60mm, 80$\times$80mm and 100$\times$100mm mushes according to the species of the fishes, besides that for crabs were not sectioned. The results of the investigation are as follows: 1. Of the feeding sound of fish, the frequency of wave from of the sound produced by Nibea albiflora and seriola quinqucradiata was 125~250Hz, that by Navodon modestus 63~125Hz, and that by Fugu xanthopterus 400~500Hz. The pressure level of the feeding sound produced by Nibea albiflora and Seriola quinqueradiata was 56~62db, that by Navodon modestus 57~59db, and that by Fugu xanthopterus 60~64db. 2. Of the croaking sound of Nibea albiflora, the frequency of the sound was 125~250Hz almost equivalent to that of feeding sound, and the pressure level was 62~63db, slightly higher than that of feeding sound. 3. Of the croaking sounds of crabs, the frequency of the sound produced by scylla serrata was 125~250Hz, that by Charybdis japonica and Telmessus acutidens 500~1,000Hz, and that by Portunus trituberculatus 250~500Hz. The pressure level of the croaking sound by Scylla serrata was 68~70db, and that by Charybdis japonica, Telmessus acutidens and Portuens trituberculatus 50~62db. 4. Phonotactic responses of Nibea albiflora and Seriola quinqueradiata to the feeding sounds produced by their own species, the same body length were conspicuous with the phonotactic index of 56~87%, but that of Navodon modestus, Chrysophrys major and Fugu xanthopterus were hardly recognized. 5. Phonotactic responses of the sample fishes to the sinusoidal sound with the frequency range of 50 to 9,000 Hz were observed not conspicuous. 6. Phonotactic responses of Portunus trituberculatus to the croaking sounds produced by their own species was varied in the range of 40~100%, according to the carapace length and the sex.

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