• Title/Summary/Keyword: 8PSK

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The effects of estradiol and its metabolites on the regulation of CYP 1A1 expression.

  • Joung, Ki-Eun;Sheen, Yhun-Yhong
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.294.1-294.1
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    • 2002
  • The effects of estradiol and its metabolites on the regulation of CYP1A1 expression. K.E. Joung and Y.Y. Sheen College of Pharmacy, Ewha womans University, Seoul. 120-750, Korea 2, 3.7.8-Tetrachlorodibenzo-p-dioxin (TCDD) is the most potent halogenated aromatic hydrocarbon congener that induces expression of several genes including CYP1A1. Exposure to TCDD results in many toxic actions such as carcinogenesis, hepatotoxicity. immune suppression. and reproductive and developmental toxicity. (omitted)

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Diasteroselective synthesis of long chained keto amino acids derivatives

  • Kim, Eun-Young;Kim, Eun-Jung;Ko, Hyo-Jin
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.347.2-347.2
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    • 2002
  • The unusal keto amino acid. (s)-2-amino-8-oxodecanoic acid(Aoda) is a biologically important constituent of the naturally occurring cyclic tetrapeptides such as apicidins. Consequently extensive chemical modifications of Aoda residue of apicidin were studied, and we are obtained the practical and versatile synthesis of the long-chained keto amino acids in enantlomerically pure form by alkylation with bromoketone and chiral Scholkopf auxiilary. (omitted)

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Studies on the protective effect of Cheju and Brazil pectin on the male reproductive system damaged by 2.3.7.8-tetrachlorodibenzo-P-dioxin

  • Shim, Kyoo-Jung;Choung, Se-Young
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.283.1-283.1
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    • 2002
  • The adverse health effects on humans and domestic and wildlife species by exposing to environmental contaminants. which interact with the endocrine system. have he en treated as an important issue without hesitation throughout the 1990s. The chemicals with practical and/or potential interfering actions with the endocrine system functions are called endocrine disrupting chemicals (EDCs). (omitted)

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Antifungal activities of 2-arylthio-,2-arylthio-5-methoxy-,2,3-bisarylthio-juglones and 2,3-bisarylthio-5,8-dimethoxy-1 A-naphthoquinones

  • Shim, Ju-Yeon;You, Hea-Jung;Choi, Ko-Un;Choi, Ik-Hwa;Chae, Mi-Jin;Ryu, Chung-Kyu
    • Proceedings of the PSK Conference
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    • 2002.10a
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    • pp.350.3-351
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    • 2002
  • 2-Arylthio-, 2-arylthio-5-methoxy-, 2, 3-bisarylthio-juglones and 2, 3-bisarylthio-5, 8-dimethoxy-1, 4-naphthoquinones were newly systhesized for the evaluation of antifungal activities. These derivatives were prepared by methylation of juglone and 2, 3-dichloro-5, 8-dihydroxy-1, 4-naphthoquinone. and by resioselective nucleophilic subsitution with arylthiols. All compounds were tested in vitro for their growth inhibitory activities against pathogenic fungi by the standard method. The MIC values were determined by comparison to flucytosine as a fungicidal standard agent. In general. In general. most juglone derivatives shows in vitro antifungal activities. Among them. 2-arylthio-5-methoxy-juglones showed most potent antifungal activities against all pathogenic fungi.

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Implementation and Evaluation of the 100 Watt High Power Amplifier for Broadband Digital TV Repeater (광대역 디지털TV 중계기용 100 Watt 고출력증폭기의 구현 및 특성 측정에 관한 연구)

  • Sung, Jeon-Joong
    • Journal of Advanced Marine Engineering and Technology
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    • v.31 no.5
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    • pp.575-582
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    • 2007
  • In this paper, a 100 Watt high power amplifier has been implemented and performed evaluation, which is operating at UHF band ($470\;{\sim}\;806\;MHz$) for Digital TV repeater. To achieve increase of bandwidth and high power capability, 3-way power combiner and divider of Wilkinson type was adopted. In order to measure the fabricated 100 Watt power amplifier, the estimation technique function which makes equivalent mask was used. As a result of the measurement, the existence of pilot signal is confirmed and the signal transmitted at the rated output power 100 Watt is brought out the flat feature through 6 MHz bandwidth. and it resulted that its value was less than -47 dB at the edge of radiation channel and less than -110 dB at more than 6 MHz position from channel edge.

Aldose Reductase Inhibitory Constituents from Ganoderma applanatum

  • Shim, Sang-Hee;Ryu, Ji-Young;Kim, Ju-Sun;Kang, Sam-Sik;Chung, Sang-Hun;Lee, Yeon-Sil;Lee, Sang-Hyun;Shin, Kuk-Hyun
    • Proceedings of the PSK Conference
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    • 2003.04a
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    • pp.261.1-261.1
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    • 2003
  • The EtOAc and CH$_2$Cl$_2$ soluble fractions from the fruit body of Ganoderma applanatum showed strong aldose reductase inhibitory activity. Nine compounds were isolated from both fractions. They were identified by spectral data as D-mannitol (1), 2-methoxyfatty acid (2), cerebrosides [(2S,3R,4E,8E)-1-O-${\beta}$-D-glucopyranosyl-3-hydroxy-2-[(R)-2'-hydroxypalmitoyl]amino-9-methyl-4,8-octadecadiene] (3), daucosterol (4), 2,5-dihydroxybenzoic acid (5), protocatechualdehyde (6), 5-dihydroergosterol (7), ergosterol peroxide (8), and cerevisterol (9). (omitted)

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Immunogenicity and protective effects of a novel reassortant influenza live virus, NC-22-8

  • Chung, Young-Mee;Kim, Seong-Woo;Chun, Hyung-Ok;Kim, Young-Gi;Kim, Hyun-Ah;Kim, Yeon-Hee;Ha, Suk-Hoon;Chae, Myeong-Yun;Park, Wan-Je
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.135.3-136
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    • 2003
  • In the present study, type A influenza live virus, NC-22-8, which is a combination of a cold-adapted attenuated donor virus (HTCA-A101) and a wild type virus (A/New Caledonia/20/99), was constructed and the efficacy of this new virus was assessed by immunogenicity and protection tests in the mouse model. NC-22-8 (1'$10^7, 1'10^5, 1'10^3$ pfu/mouse) was intranasally administered to mice. Four weeks later, the titers of specific IgG and haemagglutinin inhibiton (HI) were measured from blood and the titer of secretary IgA (sIgA) was also detected from boncho alveolar lavage (BAL) and mucosal fluid. (omitted)

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Involvement of Akt in mitochondria-dependent apoptosis induced by a naphthoquinone analog

  • Kang, Seung-Koo;Kim, Hae-Jong;Chun, Young-Jin;Kim, Mie-Young
    • Proceedings of the PSK Conference
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    • 2003.10b
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    • pp.158.2-158.2
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    • 2003
  • Vitamin K-related analogs induce growth inhibition in various cancer cell lines. We report that 2,3-dichloro-5,8-dihydroxy-1, 4-naphthoquinone (DDN), a naphthoquinone analog, induces mitochondria-dependent apoptosis in human promyeloid leukemic HL-60 cells. DDN induced cytochrome c release, cleavage of Bid, and activation of caspases -8, -9 and -3. Cleavage of Bid, the caspase-8 substrate, was inhibited by the broad caspase inhibitor zVAD-fmk, whereas cytochrome c release was not affected by zVAD-fmk. (omitted)

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Performance Analysis of Rotation-lock Differential Precoding Scheme (회전로크 구조의 차분 선부호화 기법의 성능 분석)

  • Kim, Young Ju
    • Journal of the Institute of Electronics and Information Engineers
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    • v.50 no.4
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    • pp.9-16
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    • 2013
  • Long term evolution (LTE) and LTE-Advanced (LTE-A) systems adopt closed-loop multiple-input multiple-output antenna techniques. Equal gain transmission which has equal gain property is the key factor in their codebook design. In this paper, a novel differential codebook structure which maintains the codebook design requirements of LTE or LTE-A systems. Especially, eight-phase shift keying (8-PSK) constellations are used as elements of codewords, which not only maintain equal gain property but also reduce the computation complexity of precoding and decoding function blocks. The equal gain property is very important to uplink because the performance of uplink is very sensitive to the peak-to-average power ratio (PAPR). Moreover, the operation of the proposed differential codebook is explained as a rotation-lock structure. As the results of computer simulations, the steady-state throughput performance of the proposed codebook shows at least 0.9dB of SNR better than those of the conventional LTE codebook with the same amount of feedback information.