• 대한의용생체공학회:의공학회지
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• 제34권4호
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• pp.182-188
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• 2013

This study aims to develop a practical algorithm which can detect freezing of gait(FOG) in patients with Parkinson's disease(PD). Eighteen PD patients($68.8{\pm}11.1yrs.$) participated in this study, and three($68.7{\pm}4.0yrs.$) of them showed FOG. We suggested two time-domain algorithms(with 1-axis or 3-axes acceleration signals) and compared them with the frequency-domain algorithm in the literature. We measured the acceleration of left foot with a 3-axis accelerometer inserted at the insole of a shoe. In the time-domain method, the root-mean-square(RMS) acceleration was calculated in a moving window of 4s and FOG was defined as the periods during which RMS accelerations located within FOG range. The parameters in each algorithm were optimized for each subject using the simulated annealing method. The sensitivity and specificity were same, i.e., $89{\pm}8%$ for the time-domain method with 1-axis acceleration and were $91{\pm}7%$ and $90{\pm}8%$ for the time-domain method with 3-axes acceleration, respectively. Both performances were better in the time-domain methods than in the frequency-domain method although the results were statistically insignificant. The amount of calculation in the time-domain method was much smaller than in the frequency-domain method. Therefore it is expected that the suggested time domain algorithm would be advantageous in the systematic implementation of FOG detection.

• 한국통신학회논문지
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• 제21권11호
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• pp.2789-2800
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• 1996

Real time fractal coding for successive QCIF 144*176 luminance images has been implemented on a 50MHz IBM 486 personal computer. To satisfy the frame encoding speed and data compression ratio, following algorithms are adopted. In order to minimize encoding time, extension SAS being not searching of domain blocks is used. for reducing the bits per pixel, conventioal 4*4 range block is extended to 8*8 range block. and range block extension decrease quality of decoded image. For improvement quality of decoded image, the paper apply quad-tree partition mothod. In order to divide **8 range block, self-simiarity is compared 8*8 range block with spatial contractive transformed 8*8 domain block. According to self-simiarity, the block is partitioned and owing to block partition, increased encoding time is minimized. According to self-simiarity of 8*8 range block and spatial contractive transformed 8*8 domain block, number of fractal factor is varied. Simultaneously with minimizing the decrement of decoded image's quality, transmittion rate and encoding time is shorted. The results enable us to process the real-time fractal coding. For the claire test image, the average PSNR was 32.4dB, 0.12 bit rates and 33ms coding time per frame.

• 지구물리와물리탐사
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• 제7권1호
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• pp.45-50
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• 2004

This paper describes a method of detecting formation boundaries, and permeable fractures, from frequency-domain Stoneley wave logs. Field data sets were collected between the depths of 330 and 360 m in well EE-4 in the Higashi-Hachimantai geothermal field, using a monopole acoustic logging tool with a source central frequency of 15 kHz. Stoneley wave amplitude spectra were calculated by performing a fast Fourier transform on the waveforms, and the spectra were then collected into a frequency-depth distribution of Stoneley wave amplitudes. The frequency-domain Stoneley wave log shows four main characteristic peaks at frequencies 6.5, 8.8, 12, and 13.3 kHz. The magnitudes of the Stoneley wave at these four frequencies are affected by formation properties. The Stoneley wave at higher frequencies (12 and 13.3 kHz) has higher amplitudes in hard formations than in soft formations, while the wave at lower frequencies (6.5 and 8.8 kHz) has higher amplitudes in soft formations than in hard formations. The correlation of the frequency-domain Stoneley wave log with the logs of lithology, degree of welding, and P-wave velocity is excellent, with all of them showing similar discontinuities at the depths of formation boundaries. It is obvious from these facts that the frequency-domain Stoneley wave log provides useful clues for detecting formation boundaries. The frequency-domain Stoneley wave logs are also applicable to the detection of a single permeable fracture. The procedure uses the Stoneley wave spectral amplitude logs at the four frequencies, and weighting functions. The optimally weighted sum of the four Stoneley wave spectral amplitudes becomes almost constant at all depths, except at the depth of a permeable fracture. The assumptions that underlie this procedure are that the energy of the Stoneley wave is conserved in continuous media, but that attenuation of the Stoneley wave may occur at a permeable fracture. This attenuation may take place at anyone of the four characteristic Stoneley wave frequencies. We think our multispectral approach is the only reliable method for the detection of permeable fractures.

• Animal cells and systems
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• 제3권3호
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• pp.331-336
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• 1999

p56$^{Ick}$, a cytoplasmic protein tyrosine kinase of the src family, is non-covalently associated with the cell surface coreceptors CD4 and CD8, which are expressed on thymocytes and mature T cells. The coreceptor protein plays an important role during the differentiation of thymocytes and the activation of T cells. DNA constructs were designed to study the roles of CD4 and CD8 during the differentiation of thymocytes. One is a chimeric cDNA which consists of coding regions for the extracellular domain of CD8a and the transmembrane and cytoplasmic domain of CD4. The other is the same chimeric cDNA but with a point mutation converting Cys to Ala in the Ick-binding site to disrupt the association. We confirmed that the CD8a/CD4 chimeric molecule bound to Ick more efficiently than the wild type CD8a protein. However, the chimeric protein with the Cys$leftrightarro$Ala mutation did not associate with Ick. The results suggest a possibility that the CD8a/CD4 chimeric protein may behave like a CD4 protein in associating with Ick and that it may deliver a signal inside the cell in a similar manner, Analysing effects of the mutant CD8a/CD4 chimeric protein expression in developing thymocytes will elucidate the role of Ick during the determination of CD4/CD8 cell lineages.

• 한국인터넷방송통신학회논문지
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• 제19권6호
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• pp.21-27
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• 2019

동영상 압축 표준은 고해상도의 영상을 위한 처리 기술이 요구되면서 영상의 해상도 증가에 맞춰 부호화 크기를 증가시켰다. 정확한 움직임 예측과 증가된 부호화 크기는 높은 정확도와 압축률을 제공하지만 계산량 증가 문제가 발생한다. 본 논문에서는 복잡도를 줄이기 위해 주파수 영역에서 이동 행렬을 이용한 DCT 기반 움직임 예측을 사용한다. 하지만 일반적인 동영상 부호화기에 사용되는 DCT와 양자화 과정을 주파수 영역의 부호화기에 그대로 적용했을 때 스케일링 과정으로 인한 문제점이 발생함을 발견하였다. 따라서 본 논문에서는 DCT 단계에서 적용할 수 있는 스케일링 행렬을 추출하여 이를 해결하고, 증가된 부호화 크기를 이용해 움직임 예측의 성능을 높였다.

• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2008년도 추계학술대회 논문집 Vol.21
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• pp.339-340
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• 2008

The Conventional PVA (patterned vertical alignment) mode showed characteristics of 8-domain using T-T type or C-C type. But these methods have disadvantages such as decreasing aspect ratio and transmittance. In order to resolve these problems, in this paper we have studied a new 8-domain method which is partially using the UV curable reactive mesogen (RM) that is a role in surface stabilization. The characteristic of off-axis color shift is decreased because the part of surface stabilized area is compensated to other area in a pixel. Consequently, the device shows improved color shift by 8-domain.

• 한국멀티미디어학회논문지
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• 제20권8호
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• pp.1208-1215
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• 2017

Recently, people's attention and worries about fine particulate matter have been increasing. Due to the construction and maintenance costs, there are insufficient air quality monitoring stations. As a result, people have limited information about the concentration of fine particulate matter, depending on the location. Studies have been undertaken to estimate the fine particle concentrations in areas without a measurement station. Yet there are limitations in that the estimate cannot take account of other factors that affect the concentration of fine particle. In order to solve these problems, we propose a framework for estimating the concentration of fine particulate matter of a specific area using meteorological data and traffic data. Since there are more grids without a monitor station than grids with a monitor station, we used a domain adversarial neural network based on the domain adaptation method. The features extracted from meteorological data and traffic data are learned in the network, and the air quality index of the corresponding area is then predicted by the generated model. Experimental results demonstrate that the proposed method performs better as the number of source data increases than the method using conditional random fields.

• 간호행정학회지
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• 제9권1호
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• pp.5-18
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• 2003

Purpose : For improvement of nursing services in ambulatory unit, ambulatory nursing activity was identified and the required time by nursing activity was measured. Method : The data were collected from 4 tertiary hospitals and 2 secondary hospitals. The method of data collection was used the self-reporting method. The 123 nurse-work days and 137 nurse-aid-work days in 6 hospitals were analyzed. Results : As a result, 11 ambulatory nursing domains and 79 ambulatory nursing activities were confirmed. Above 50% of subjects performed the general outpatient affair domain. The percentage of total time spent in each domain were as follows : general outpatient affair domain, 58.3%, patient education ${\cdot}$ counseling domain, 10.8%, therapeutic care domain, 8.6% and so on. And the average hours were measured by activity and domain. Conclusion : For the improvement of ambulatory nursing care, the strategies that keep the legal standard of number of ambulatory nurse and exchange the nursing-aid for the nurse is needed. And it is also needed to standardize the ambulatory nursing services.

• Journal of Magnetics
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• 제13권3호
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• pp.102-105
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• 2008

This study examined the feasibility of the combining HDDR-process (hydrogenation, disproportionation, desorption and recombination) with mechanical milling to prepare single domain $Nd_2Fe_{14}B$ particles from a Nd-Fe-B alloy ingot. The $Nd_{15}Fe_{77}B_8$ alloy was HDDR-treated and then subjected to a roller-milling. In the HDDR-treated $Nd_{15}Fe_{77}B_8$ alloy, very small $Nd_2Fe_{14}B$ grains comparable to their critical single domain size(0.3 ${\mu}m$) were observed. These fine individual grains were separated successfully along the grain boundaries by a roller-milling. The separated $Nd_2Fe_{14}B$ grains were found to be single domain particles. These results suggest that single domain particles of the $Nd_2Fe_{14}B$ phase can be prepared from a Nd-Fe-B ingot alloy by combining a HDDR-process with mechanical milling.

• BMB Reports
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• 제42권8호
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• pp.506-510
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• 2009

The Toll signalling pathway in invertebrates is responsible for defense against Gram-positive bacteria and fungi, leading to the expression of antimicrobial peptides via NF-$\kappa$B-like transcription factors. Gram-negative binding protein 3 (GNBP3) detects beta-1,3-glucan, a fungal cell wall component, and activates a three step serine protease cascade for activation of the Toll signalling pathway. Here, we showed that the recombinant N-terminal domain of Tenebrio molitor GNBP3 bound to beta-1,3-glucan, but did not activate down-stream serine protease cascade in vitro. Reversely, the N-terminal domain blocked GNBP3-mediated serine protease cascade activation in vitro and also inhibited beta-1,3-glucan-mediated antimicrobial peptide induction in Tenebrio molitor larvae. These results suggest that the N-terminal GNBP homology domain of GNBP3 functions as a beta-1,3-glucan binding domain and the C-terminal domain of GNBP3 may be required for the recruitment of immediate down-stream serine protease zymogen during Toll signalling pathway activation.