• 한국전기전자재료학회:학술대회논문집
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• 한국전기전자재료학회 2004년도 추계학술대회 논문집
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• pp.1-6
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• 2004

In this paper author describe the undoped and $Co^{2+}$ (0.5mole%)doped $Cd_4GeS_6$ single crystals were grown by the chemical transporting reaction(CTR) method using high purity(6N) Cd, $GeS_2$, S elements. It was found from the analysis of X-ray diffraction that the undoped and $Co^{2+}$(0.5mole%) doped $Cd_{4}GeS_{6}$ compounds have a monoclinic structure in space grop Cc. The optical energy band gap was direct band gap and temperature dependence of optical energy gap was fitted well to Varshni equation. Impurity optical absorption peaks due to the doped cobalt in the $Cd_4GeS_6:Co^{2+}$ single crystal were observed at 3593cm-1, 5048cm-1, 5901cm-1, 7322cm-1, 12834cm-1, 13250cm-1, 14250cm-1，and 14975cm-1 at 11.3K.

• IMMUNE NETWORK
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• 제2권3호
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• pp.175-181
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• 2002

Background: S100A6 is a calcium-binding protein overexpressed in several tumor cell lines including melanoma with high metastatic activity and involved in various cellular processes such as cell division and differentiation. To detect S100A6 protein in patient' samples (ex, blood or tissue), it is essential to produce a monoclonal antibody specific to the protein. Methods: First, cDNA coding for ORF region of human S100A6 gene was amplified and cloned into the expression vector for GST fusion protein. We have produced recombinant S100A6 protein and subsequently, monoclonal antibodies to the protein. The specificity of anti-S100A6 monoclonal antibody was confirmed using recombinant S100A recombinant proteins of other S100A family (GST-S100A1, GST-S100A2 and GST-S100A4) and the cell lysates of several human cell lines. Also, to identify the specific recognition site of the monoclonal antibody, we have performed the immunoblot analysis with serially deleted S100A6 recombinant proteins. Results: GST-S100A6 recombinant protein was induced and purified. And then S100A6 protein excluding GST protein was obtained and monoclonal antibody to the protein was produced. Monoclonal antibody (K02C12-1; patent number, 330311) has no cross-reaction to several other S100 family proteins. It appears that anti-S100A6 monoclonal antibody reacts with the region containing the amino acid sequence from 46 to 61 of S100A6 protein. Conclusion: These data suggest that anti-S100A6 monoclonal antibody produced can be very useful in development of diagnostic system for S100A6 protein.

• Bulletin of the Korean Chemical Society
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• 제6권2호
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• pp.119-120
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• 1985

Stereospecific coordination of racemic 2,3-diaminobutane has been observed in the reaction with platinum(Ⅱ) complexes of optically active 6,6'-dimethyl-2,2'-diaminobiphenyl. The reaction between [Pt (R-dmdabp) Cl$_{2}$] (R-dmdabp is R-6,6'-dimethyl-2,2'-diaminobiphenyl) and unresolved bn (bn is 2,3-diaminobutane) has yielded [Pt(R-dmdabp)-(R-bn)] Cl$_{2}$ only, while the reaction of [Pt(S-dmdabp)Cl$_{2}$] with unresolvd bn has yielded [Pt(S-dmdabp) (S-bn)]Cl$_{2}$ only. On the other hand, the standard [Pt(R-dmdabp) (R-bn)] Cl$_{2}$ complex has been independently prepared from the reaction of [Pt(R-dmdabp)Cl$_{2}$] with R-bn, and the standard [Pt(S-dmdabp) (S-bn)] Cl$_{2}$ from the reaction of [Pt(S-dmdabp)Cl$_{2}$] with S-bn. The stereospecific behavior of the racemic 2,3-diamino-butane is thus confirmed from the comparison of these Pt(Ⅱ) complexes prepared using racemic bn with the standard Pt(Ⅱ) complexes prepared using R-bn or S-bn.

• Asian-Australasian Journal of Animal Sciences
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• 제14권3호
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• pp.338-345
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• 2001

An experiment was conducted to determine the optimal inclusion ratio of spray dried plasma protein (SDPP) and dried porcine solubles (DPS) for maximizing growth and improving immunity in weaned pigs. One hundred-fifty male (barrow) pigs were allotted in a completely randomized block design. Treatments were as follows: 1) control (6% SDPP), 2) S6D6 (6% SDPP+6% DPS), 3) S6D3 (6% SDPP+3% DPS), 4) S3D6 (3% SDPP+6% DPS) and 5) S3D3 (3% SDPP+3% DPS). Each treatment has 6 replicates with 5 pigs per replicate. Average daily gain (ADG) and average daily feed intake (ADFI) were highest, but not significantly different when pigs were fed a diet contained 6% SDPP and DPS from d 0 to 7 after weaning. Pigs fed the S6D3 diet showed better weight gain and feed intake than other treatments, especially compared with pigs fed S3D6 diet (p<0.05) from d 8 to 21 after weaning. For the overall experimental period, pigs fed the S6D3 diet showed the best improvement in ADG and ADFI. The digestibilities of dry matter (DM) and crude protein (CP) were higher in pigs fed the S6D6 diet than other diets from d 0 to 7 after weaning. However, pigs fed S6D3 diet showed higher DM, CP and essential amino acids (except methionine and arginine) digestibilities than pigs fed other diets from d 8 to 21 after weaning, although there was no significant difference. From d 8 to 21 after weaning, threonine, valine, isoleucine and leucine digestibilites were higher in S6D6 group, and phenyalanine, histidine, lysine and arginine digestibility were higher in S6D3 group than other groups. The ratio of CD4 and CD8 positive lymphocytes during the overall experimental period was independent of the ratio of SDPP and DPS. However, CD4+:CD8+ ratio was numerically lowered in pigs fed diet the S6D3 diet. Therefore, the present study suggests that an optimal inclusion ratio for maximizing growth performance and maintaining low immune status is 6% of SDPP and 3% of DPS in weaned pigs.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2003년도 춘계학술대회
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• pp.758-763
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• 2003

This paper describes the development of a 6-axis robot's finger force/moment sensor, which measures forces Fx, Fy, Fz, and moments Mx, My, Mz simultaneously, for making a robot's gripper. In order to safely grasp and unknown object using the robot's gripper, it should measure the force in the gripping direction and the force in the gravity direction, and perform the force control using the measured forces. Thus, the robot's gripper should be composed of 6-axis robot's finger force/moment sensor that can measure forces Fx, Fy, Fz, and moments Mx, My, Mz simultaneously. In this paper, the 6-axis robot's finger force/moment sensor for measuring forces Fx, Fy, Fz, and moments Mx, My, Mz simultaneously was newly modeled using several parallel-plate beams, designed, and fabricated. The characteristic test of made sensor was performed. Also, Robot's gripper with the 6-axis robot's finger force/moment sensor for the characteristic test of force control was manufactured, and the characteristic test for grasping an unknown object was performed using it.

• 한국건설관리학회논문집
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• 제6권4호
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• pp.133-141
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• 2005

본 연구는 6시그마 경영기법의 건설업에 대한 적용 성과를 분석하고자 수행하였다. 이를 위하여 S 건설업체의 조직 및 인력별 6시그마 적용 프로젝트의 품질비용을 분석하고, S 건설업체의 임직원들을 대상으로 6시그마 경영에 대한 설문조사를 실시하였다. 위와 같은 목적과 방법에 따라 진행된 본 연구의 결과를 요약하면 다음과 같다. : 1) S 건설업체의 6시그마 경영기법의 도입은 03년과 04년에 걸쳐 258건의 프로젝트를 수행하면서 품질비용 절감효과를 발생시켰다. 또한, S 건설업체는 6시그마 적용 전 시그마 수준이 업무 분야별 평균 2.8이었으나, 적용 후 평균 3.6으로 향상되었다. 특히, 공사 관리 분야는 적용 전 1.3시그마에서 적용 후 2.6시그마로 매우 높은 향상율을 보였다. 2) 6시그마 경영활동에 대한 업무수행 기대성과에 관한 분석결과 대다수의 직원들은 6시그마 경영이 비용절감 효과가 있으며, 품질향상에 도움이 되는 것으로 인식하고 있었다. 그러나 현 시점은 S 건설업체에 있어 6시그마 경영기법의 도입 초기단계이므로 업무처리의 효율성에는 큰 효과를 보이지 않는 것으로 조사되었다.

• 디자인융복합연구
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• 제14권4호
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• pp.193-208
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• 2015

본 연구는 중국영화 6세대 영화에 등장하는 캐릭터의 비극성을 통해 6세대가 보여주고자 하는 비극의 의미를 논하고자 한다. 이를 위해 6세대를 대표하는 감독 작품 중에 비극의 순간과 표면화 된 엔딩에 감추어진 내면적 특성을 들여다보고자 한다. 중국영화 6세대는 1990년대 중국영화의 문화지형을 새롭게 재편하였다. 제도권에 있던 주선율(主旋律)과 5세대의 반기를 들고 나타난 6세대 영화는 영화 속에 공통적으로 등장하는 비극적 순간을 시공간과 함께 캐릭터의 비극성으로 표출되고 있다. 비극적인 순간에 놓인 6세대 영화 속 주인공은 비극의 순간을 벗어나고자 다양한 노력을 시도한다. 그러나 그들은 벗어날 수 없는 현실의 벽에 부딪히고, 표면화 되지 않은 은폐된 감정으로 극을 이끌어간다. 6세대 영화는 비극을 맞이하는 순간, 그 이전부터 축적되어온 주인공의 비극적 상황들이 함께 전개되며, 과거의 상처에 함몰된 비극, 직업의 상실에 따른 비극, 가족의 일탈에 따른 비극, 혼란의 시대가 가져온 비극, 가족의 가장이 된 여성의 비극 등을 통해 캐릭터의 비극성이 형상화되고 있다.

• 수산해양기술연구
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• 제31권3호
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• pp.272-278
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• 1995

강도가 각각 다른 세 종류의 프리프레그를 사용하여 일방향 CFRP를 적층하였으며, 모드 I과 모드 II 실험을 통하여 층간 파괴인성치를 고찰하였고, 또한 적층 섬유방향을 변화시킨 사교적층판의 그것도 함께 고찰하였으며, 이를 요약하면 다음과 같다. 1) 임계에너지 방출률 G 하(IC)의 값을 컴플라이언스 법, 수정 컴플라이언스 법, 그리고 보이론에 의해 계산하여 비교 검토한 결과 본 연구에서 사용한 수정식에 의한 값들이 거의 일치하였다. 2) G 하(IC) 값은 대체로 프리프레그의 C, B, A재의 순으로 높게 나타났으며, G 하(II C)의 값을 세가지 식에 의해 계산하여 비교 검토한 결과 거의 일치하였다. 3) 사교적층판의 경우 G 하(IC) 값은 [0/90] 하(6s), [0/45] 하(6s), [0/45/90] 하(6s)의 순으로 높게 나타났으며, G 하(II C)는 [0/90] 하(6s), [0/45/90] 하(6s), [0/45] 하(6s)의 순으로 높게 나타났다. 4) 사교적층판과 일방향의 임계에너지 방출률을 비교하였을 때, 모드 I의 경우 일방향의 결과가 다소 높았으며, 모드 II의 경우는 [0/45] 하(6s)의 결과는 거의 일치함을 알 수 있었다.

• 약학회지
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• 제47권6호
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• pp.450-455
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• 2003

Synthesis of (lR,5S,6S)-6-[(lR)-1-hydroxyethyl] -2-[(3S,5S)-5-(2-ethoxycarbonyl-1-moxy(hydroxy)iminoethyl)pyrrolidine-3-ylthio]-1-methylcarbapen-2-em-3-carboxylic acids (10a,l0b) were described. Methyl(2S,4S)-4-tritylthio-1-(allyloxycarbonyl)pyrrolidine-2-carboxyla late (I) was prepared from trans-4-hydroxy-L-proline with (2S,4R)-abs olute configuration as starting material. (2S,4S)-1-allyloxycarbonyl-2-(2-ethoxycarbonyl-hydroxy(methoxy )iminoethyl)-4-mercapto- pyrrolidines (6,7) were obtained from the tritylthio compound (I). (lR,5S,6S)-6-[(lR)-1-hydroxyethyl]-2-[(3S,5S)-5-(2-ethoxycarbonyl-1-methoxy(hydroxy)imino-ethyl)pyrrolidine-3-ylthio]-1-methylcarbapem-2-em-3-carboxylic acids (10a,10b) were obtained by the coupling reaction with carbapenem diphenylphosphates (8) and pyrrolidine-thiol moiety (6,7). Their in vitro antibacterial activities against both Gram-positive and Gram-negative were tested. Compounds ( 10a,10b) showed potent antibacterial activity except pseudomonas aerusinosa.

• BMB Reports
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• 제39권6호
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• pp.782-787
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• 2006

A new protein was cloned and identified as the sixth subunit of Choristoneura fumiferana origin recognition complex (CfORC6). The newly identified 43 kDa protein CfORC6 is much bigger than DmORC6 (25.7 kDa) and HsORC6 (28.1 kDa), though it's 23.85% identical to DmORC6 and 23.81% identical to HsORC6. Although the molecular weight of CfORC6 is close to ScORc6 (50 kDa), CfORC6 is only 14.03% identical to ScORC6. By alignment, it was found that the N-terminal of CfORC6 has about 30% identities with other ORC6s, but about 100aa of C-terminal of CfORC6 has no identity with other ORC6s. Like ScORC6, CfORC6 has many potential phosphorylation sites, (S/T)PXK. Like DmORC6, CfORC6 has leucine-rich region in the relevant site. Northern Blot showed that CfORC6 mRNA is about 2,000nt. Southern Blot confirmed that there is one copy of CfORC6 gene in spruce budworm genome. Western blot showed that infection of Cf124T cells with CfMNPV didn't affect the expression levels of CfORC6, at least up to 26 hr post infection.