• Journal of Digital Contents Society
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• v.11 no.3
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• pp.341-348
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• 2010

Unlike host-based IPv6 mobility support protocols such as Mobile IPv6 (MIPv6), Hierarchical Mobile IPv6 (HMIPv6), and Fast handover for Mobile IPv6 (FMIPv6), Proxy Mobile IPv6 (PMIPv6) is expected to accelerate the real deployment of IPv6 mobility support protocol by using only collaborative operations between the network entities without mobile node (MN) being involved. In this paper, we analyze and compare the handover latency of network-based IPv6 mobility support protocol (i.e., PMIPv6) with the representative host-based IPv6 mobility support protocols such as MIPv6, HMIPv6, and FMIPv6. Analytical results show that the handover latency of PMIPv6 is considerably lower than those of MIPv6 and HMIPv6, and the handover latency of PMIPv6 becomes lower than that of FMIPv6 in case the wireless link delay is greater than the delay between mobile access gateway (MAG) and local mobility anchor (LMA).

• BMB Reports
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• v.31 no.5
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• pp.519-523
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• 1998

We have previously reported that anti-glucose-6-phosphate dehydrogenase (G6PD) serum raised against native G6PD (nG6PD) enzyme recognized nG6PD antigen poorly in competitive enzyme-linked immunosorbent assay (ELISA) (Kim, 1997). In the present study, we investigated whether anti-G6PD serum raised against nG6PD can react with denatured G6PD effectively in competitive ELISA. We used partially active G6PD (paG6PD) by repeated freeze-thawing or SDS-denatured G6PD (SDS-G6PD) as both immobilized and soluble antigens, and anti-G6PD serum raised against nG6PD for competitive ELISA. The polystyrene cuvettes coated with either paG6PD or SDS-G6PD were challenged with a mixture of a limiting amount of anti-G6PD serum and various doses of paG6PD or SDS-G6PD as competitors, followed by incubation with alkaline phosphatase-anti-IgG conjugate. The competitive ELISA with paG6PD or SDS-G6PD antigen exhibited the sigmoidal dose-response curve characteristic of competition immunoassays. Furthermore, Triton-denatured G6PD (Triton-G6PD) was used in competitive ELISA. The paG6PD, SDS-G6PD, or Triton-G6PD used as competitors increased the inhibition of antibody binding to immobilized either of nG6PD or denatured G6PD compared with nG6PD competitor. The inhibition by denatured G6PD competitors was more pronounced at high competitor concentrations than at low counterparts. We conclude that anti-G6PD serum raised against nG6PD can effectively react with denatured G6PD in competitive ELISA and that our anti-G6PD serum recognizes denatured enzymes better than active enzymes.

• The Korean Journal of Zoology
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• v.34 no.2
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• pp.228-231
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• 1991

The phenotyping of the sixth complement component (C6) was performed on plasma or serum samples from 383 unrelated Korean, by IEF and immunoblotting using anti-human C6 serum. Three common allotypes, C6 A, C6 B and C6 B2 and two rare allotypes, C6 Ml and C6 Mu were observed. The allele frequencies of C6*A, C6*B and C6*B2 were estimated to be 0.4399, 0.5144, 0.0392, respectively. These frequencies are similar to those of the Eastasian populations.

• The Journal of the Institute of Internet, Broadcasting and Communication
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• v.13 no.5
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• pp.121-133
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• 2013

Defect-free transfer service on the Next-generation wireless network extensive roaming mobile node (MN) to provide efficient mobility management has become very important. MIPv6(Mobility IPv6) is one of mobility management scheme proposed by IETF(Internet Engineering Task Force), and IPv6-based mobility management techniques have been developed in various forms. One of each management techniques, IPv6-based mobility management techniques for PMIPv6 (MIPv6) system to improve the performance of a variety of F-PMIPv6 (Fast Handover for Proxy MIPv6) is proposed. However, the F-PMIPv6 is cannot be excellent than PMIPv6 in all scenarios. Therefor, to select a proper mobility management scheme between PMIPv6 and F-PMIPv6 becomes an interesting issue, for its potenrials in enhancing the capacity and scalability of the system. In this paper, we develop an analytical model to analyze the applicability of PMIPv6 and F-PMIPv6. Based on this model, we design an Secure Smart Mobility Support(SSM) scheme that selects the better alternative between PMIPv6 and F-PMIPv6 for a user according to its changing mobility and service characteristics. When F-PMIPv6 is adopted, SSM chooses the best mobility anchor point and regional size to optimize the system performance. Numerical results illustrate the impact of some key parameters on the applicability of PMIPv6 and F-PMIPv6. Finally, SSM has proven even better result than PMIPv6 and F-PMIPv6.

• Clinical and Experimental Pediatrics
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• v.48 no.5
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• pp.506-511
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• 2005

Purpose : Streptococcus pneumoniae serotype 6B and 6A are important pathogens in pneumococcal infections. It is commonly assumed that the 6B vaccines elicit antibodies cross-reacting with the 6A serotype and the cross-reactive antibodies protect against infections of 6A. To examine this assumption, we measured the opsonophagocytic capacity to serotype 6A and 6B in adults. Methods : Twenty-four adults were immunized with pneumococcal PS vaccine that contains 6B PS. Their preimmune and postimmune sera were studied for the capacity to opsonize 6B and 6A serotypes with opsonophagocytic killing assay. Results : Opsonization titers to 6B were significantly higher than those to 6A in preimmune and postimmune sera. Because significant increasesof opsonization titers were observed in adults with polysaccharide vaccines for 6A(cross-reactive) serotype as well as for 6B(vaccine) serotype, 6B PS in vaccine elicited cross-protective antibodies to 6A, but not in all cases. One adult did not have detectable levels of opsonization titers to 6A after immunization. Conclusion : Although 6B PS in pneumococcal PS vaccine elicits antibodies cross-reacting with 6A serotype in some adults, it may not occur always. This study should be extended to other age groups such as children and elderly people. The presence of the cross-protection should be directly determined in clinical trials of the pneumococcal vaccines as well as during the postlicensure monitoring surveys by serotyping the clinical isolates of pneumococci.

• BMB Reports
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• v.39 no.6
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• pp.782-787
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• 2006

A new protein was cloned and identified as the sixth subunit of Choristoneura fumiferana origin recognition complex (CfORC6). The newly identified 43 kDa protein CfORC6 is much bigger than DmORC6 (25.7 kDa) and HsORC6 (28.1 kDa), though it's 23.85% identical to DmORC6 and 23.81% identical to HsORC6. Although the molecular weight of CfORC6 is close to ScORc6 (50 kDa), CfORC6 is only 14.03% identical to ScORC6. By alignment, it was found that the N-terminal of CfORC6 has about 30% identities with other ORC6s, but about 100aa of C-terminal of CfORC6 has no identity with other ORC6s. Like ScORC6, CfORC6 has many potential phosphorylation sites, (S/T)PXK. Like DmORC6, CfORC6 has leucine-rich region in the relevant site. Northern Blot showed that CfORC6 mRNA is about 2,000nt. Southern Blot confirmed that there is one copy of CfORC6 gene in spruce budworm genome. Western blot showed that infection of Cf124T cells with CfMNPV didn't affect the expression levels of CfORC6, at least up to 26 hr post infection.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.35 no.8B
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• pp.1115-1121
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• 2010

The DNAv6 was designed to support fast attachment for a host, which is corresponding to the movement detection part in the mobility management. Since, however, the DNAv6 has supported only DNAv6-capable ARs and DNAv6-capable hosts, an non-DNAv6 host could not support fast handoff function in a DNAv6 network. In this paper, we consider a new method of the fast attachment of non-DNAv6 hosts. To support the non-DNAv6 host in DNAv6 networks, we suggest a novel algorithm, RCA algorithm, where an AR can decide whether a host has the DNAv6 function and whether it has moved to a new link or not, and then the AR can inform the host of new link information. For the RCA algorithm, we proposed to modify the RS message and the Reconf_Link message with addition of some fields. To validate our RCA algorithm and its performance, we have accomplished simulation tests for the ND process, the DNAv6 process and the modified DNAv6 process with our RCA algorithm. In the viewpoints of the attachment delay and complexity, the proposed algorithm gives the better delay performance than the ND process while it presents the less complexity than the DNAv6 process.

• Tuberculosis and Respiratory Diseases
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• v.48 no.4
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• pp.464-470
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• 2000

Background : The recognition of bronchial asthma as an inflammatory disease led to the search for soluble markers that would be useful in assessing airway inflammation. Interleukin-6 (IL-6) is a representative proinflammatory cytokine that has been shown to be connected with various inflammatory diseases. IL-6 acts via specific receptors that consist of the IL-6 binding glycoprotein gp80 and the signal transducer gp130. In the search for markers of airway inflammation, delete the role of soluble interleukin-6 receptor (sIL-6R) and IL-6 in acute asthma were investigated. Methods : Serum levels of sIL-6R and IL-6 were measured in 78 acute asthmatics, in 15 patients with asymptomatic asthma and in 10 healthy control subjects by a specific ELISA using a murine antihuman IL-6R, IL-6 mAb ($Quantikine^{(R)}sIL$-6R, IL-6). Results : Serum levels of IL-6 in acute asthmatics significantly exceeded those of control subjects. The levels of sIL-6R in acute asthmatics were also significantly increased compared to those of control subjects. The serum concentrations of IL-6 obtained in acute asthmatics were elevated compared with those in asymptomatic asthmatics. However, association between eosinophilic count/IgE and IL-6/sIL-6R in acute asthma could not be found. Conclusion : Our results suggest that IL-6 may be involved in the pathogenesis of acute asthma, and serum levels of IL-6 and sIL-6R may reflect the severity of airway inflammation.

• Clinical and Experimental Pediatrics
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• v.45 no.12
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• pp.1497-1502
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• 2002

Purpose : We evaluated allele frequencies and distribution of surfactant protein A1(SP-A1) in Korean neonates in order to estimate prevalence of RDS to find out new SP-A alleles, and to establish new steroid therapy. Methods : Genomic DNA was extracted from 100 neonates and served as a template in PCR for genotype analysis. SP-A gene-specific amplications and gene-specific allele determinations were performed using PCR-RFLP methods. Results : The distribution for the alleles of the SP-A1 gene in the study population were 6A, $6A^2$, $6A^3$, $6A^4$, $6A^8$, $6A^9$, $6A^{10}$, $6A^{11}$, $6A^{12}$, $6A^{13}$, $6A^{14}$, $6A^{15}$, $6A^{16}$, $6A^{17}$, $6A^{18}$, $6A^{20}$. The specific frequencies for the alleles of the SP-A1 gene in the study population were : $6A^2=21%$, $6A^3=45%$, $6A^4=11%$, $6A^8=9%$, $6A^{14}=8%$. Conclusion : The frequency of $6A^3$ was higher than the other SP-A1 alleles in Korean neonates. This finding suggests that the prevalence of RDS in Korea may be low compared with other countries. However, this finding also suggests that Korean neonates have a high risk of infection.

• Proceedings of the Korean Information Science Society Conference
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• 1998.10a
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• pp.483-485
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• 1998

6Bone(IPv6 Backbone)은 IPv6 환경의 개발 촉진 및 진화를 위해 만든 전세계적인 실험망이다. 본 논문은 국내 6Bone인 6Bone KR의 구축을 위해 주소 할당 및 라우팅 규칙을 정의한 내용을 기술한다. 기존의 6Bone 주소 구조를 알아보고, 6Bone KR의 주소 체계가 어떻게 기존의 6Bon을 따르면서, 6Bone KR의 계층적 전개를 위한 연결 규칙을 가지는 가를 살펴본다. 그리고 현재 6Bone KR이 구성된 상황과 개발한 연결 테스트의 프로그램을 소개한다. 이밖에 6Bone KR진화를 위한 몇 가지 고려사항들을 분석하고, 이것을 기반으로 Renumbering을 이용한 새로운 이동 IPv6 환경을 제안한다.