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Capnographic Monitoring of End-Tidal Partial Pressure of Carbon Dioxide in Anesthetized Cinereous vultures (Aegypius monachus) (독수리(Aegypius monachus)의 흡입마취에서 Capnography를 이용한 호기말 이산화탄소분압 모니터링)

  • Park, Won-Kyu;Seok, Seong-Hoon;Park, Se-Jin;Lee, Seung-Yong;Kim, Young-Ki;Hwang, Jae-Min;Jeong, Dong-Hyuk;Lee, Hee-Chun;Yeon, Seong-Chan
    • Journal of Veterinary Clinics
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    • v.32 no.4
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    • pp.380-384
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    • 2015
  • The relationships between end-tidal partial pressure of carbon dioxide ($P_{ET}CO_2$) and arterial partial pressure of carbon dioxide ($P_aCO_2$), and between $P_{ET}CO_2$ and blood pH in isoflurane-anesthetized cinereous vultures were evaluated. Nine cinereous vultures (weighing 7.3-9.5 kg) were anesthetized via mask with isoflurane, intubated, and connected to a mechanical ventilator. By mechanical ventilator, respiratory rate was altered to achieve a $P_{ET}CO_2$ randomly selected among 30 to 35 mmHg. $P_aCO_2$ and blood pH were determined in serial arterial samples and compared with concurrent $P_{ET}CO_2$ measured with a sidestream capnography. Thirty six samples, nine cinereous vultures were tested 4 times each, were used to determine correlations coefficients between $P_aCO_2$ and $P_{ET}CO_2$, and between $P_{ET}CO_2$ and blood pH. Strong correlations were observed between $P_aCO_2$ and $P_{ET}CO_2$ (r = 0.951, P = 0.000, y = 1.679x - 30.236, $R^2=0.905$) as well as between $P_{ET}CO_2$ and blood pH (r = -0.728, P = 0.000, y = -0.024x + 8.389, $R^2=0.530$) with Pearson's correlation coefficient and simple linear regression. These results suggest that the capnography used provided a sufficiently accurate estimation of $P_aCO_2$ and blood pH. Thus, the monitoring of $P_{ET}CO_2$ can be useful method to prevent hypoventilation for cinereous vultures receiving mechanical ventilation.

Fresh-water Algae Occurred in Paddy Rice Fields - V. Fertilizer Response and Chemical Control (논발생(發生) 담수조류(湛水藻類)에 관(關)한 연구(硏究) - V. 시비반응(施肥反應) 및 방제(防除))

  • Lee, H.K.;Park, J.E.;Ryu, G.H.;Lee, J.O.;Park, Y.S.
    • Korean Journal of Weed Science
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    • v.13 no.1
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    • pp.1-6
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    • 1993
  • The experiments were conducted in order to find out the response of algae as affected by fertilizer and salinity, and to determine the chemical control method of algae in 1991. The higher the nitrogen fertilizer level, the more the occurrence of a blue-green alga Oscillatoria concerning with soil flakes. An increase in phosphorus fertilizer level stimulated the growth of green alga Hydrodictyon, whereas an increase in nitrogen level caused its abrupt reduction due to the harmful effect at high concentration of nitrogen, The high level of nitrogen fertilizer also reduced the growth of Euglena, although the detrimental effect was less compared with that of Hydrodictyon. A blue-green alga Oscillatoria, a green alga Cladophora and a diatom Navicula were tolerant to salinity. Piperophos/dimethametryn was highly effective in controlling various algae such as a green alga Hydrodictyon, suspended unicellular green algae and Euglena species. A fungicide propineb and copper sulfate also effectively controlled Hydrodictyon.

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A Review of Experimental study on Dementia in Oriental medicine;within Oriental medicine journal since 2000 (치매에 대한 최신 실험적 연구 동향;2000년 이후 한의학 학술지를 중심으로)

  • Choi, Sung-Youl;Kim, Dae-Hyun;Kim, Sang-Tae;Kim, Tae-Heon;Kang, Hyung-Won;Lyu, Yeong-Su
    • Journal of Oriental Neuropsychiatry
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    • v.19 no.1
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    • pp.125-146
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    • 2008
  • Objectives : The purpose of this study is to suggest for the following experimental study of dementia by reviewing recent oriental medicine journals that have been published since 2000. Methods: We have investigated various types of studies in relation to dementia through 90 articles that have been published from 2000 to 2007 in recent oriental medicine journals were registered Korea research foundation. Results and Conclusions : 1. Since 2000, 88 articles in relation to dementia have been published and almost of them are herbal medicine-centered studies. Also they show a tendency to increase every year. The journal of oriental neuropsychiatry carries the highest number of studies in relation to dementia. 2. According to the experimental paper, there are 30 cases of using herb simplexes, 48 cases of herb-combined prescription, and 10 cases of other ways. Especially 7 cases of using herb-combined prescription relation to Sasang constitution are all for the Taeumin. 3. There are 85 cases of Animal and cellular experimental, 60 cases of using pathologic model induced cytotoxic activity, a case of using L-NAME, 3 cases of 192 saporin, 4 cases of ibotenic acid, 10 cases of focal cerebral ischemia, 3 cases of alcohol-administered, and one case of natural degradation. 4. Moms water maze, Radial arm maze Passive avoidance learning model were using for examining learning and memory of model animal 5. We propose that following studies of dementia are to he investigated of the applied method of using siRNA with tranceduced gene, sample preparation by water-soaking, oriental medical diagnosis, standardization of differentiating symptom and herb simplexes, building the database by classified prescriptions, and experiment model which are based on precise examining mechanism with cell line as like mouse H19-7 hippocampus, rat HT22 hippocampus, astrocyte, microglia, using the model of animals at APP, PS1, BACE, CT99/PS1, APOE4, Tau, APP/PSI/Tau

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Epidemiological Survey on Metugonimus yokogawui Infection in the Eastern Coast area of Kangwon-Province, Korea (강원도 동해시 황강흡충 감염의 역학적 조사연구)

  • 안영겸;정평림
    • Parasites, Hosts and Diseases
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    • v.25 no.1
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    • pp.59-68
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    • 1987
  • An epidemiological survey on Metagonimus yokogawai infection was performed in the eastern coast area of Kangwon province. Formalin-ether concentration technique and Stoll's dilution egg counting method were employed to figure out the prevalence and intensity of M. yokogawai infection and eating habits of inhabitants with raw freshwater fish. The results are summarized as follows: 1. The prevalence rate of M. yokogawai infection was 6.6% among a total of 2, 357 examinees; 8.6% (115 out of 1, 345) in male and 4.0% (40 out of 1, 012) in female. 2. The prevalence rates were different by the streams where the examinees were residing: 17.8% along the area of Ohsip-cheon (stream), 11.8% along Maeup-cheon, 1.7% along Hwasang-cheon, 1.3% along Yeongok-cheon, 0.9% along Namdae-cheon, 0.9% along Sa-cheon and 0% in the other streams (Yongchon-cheon, Kangnung Namdae-cheon and Jusoo.cheon) in decreasing order. 3. By social strata, the positive rate was 8.0% (122 out of 1, 521) in general inhabitants and 3.9% (33 out of 836) in school children. 4. By the intensity of infection by means of EPG counts in feces; the light infection (less than 400/EPG) was 74.1%, moderate infection (401-1, 000/EPG) 17.3% and heavy infection (more than 1, 001/EPG) 8.6%. 5. Twelves out of 50 sweetfish (Plecoglossus altivelis) (24%) caught from the streams in eastern coast of Kangwon-Do were infected with metacercariae of M. yokogawai, and the number of larvae detected were 70.7 per 6sh in average. The metacercarial infection rates in fish were also different by the streams; 100% in Ohsip-cheon of Samcheok-Gun, 14.3% in Sa-cheon, 16.7% in Yeongokcheon of Myeongju-Gun and 0% in Namdae-cheon of Yangyang-Gun, respectively. 6. Six hundred ninety live (695) out of 1, 396 inhabitants and school children (49.8%) were experienced in eating raw freshwater fishes (Plecoglossus altivezis, Triboledon hakonensis, Coreoperca sp., Morose sp., Carassius sp. & Cyprinus sp. and Zacco platypus). The data were assayed with the questionnaire collected from the examinees. In summarizing the above results, it is known that the Ohsip-cheon area of Samcheok-Gun is highly infected region, and the other areas of Kangnung Namdae-cheon, Yeongok-cheon and Yangyang Namdae-cheon are very lowly infected or non-infected regions for M yokogawai infection.

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A ground theory approach on fatigue of the female elderly with osteoarthritis (관절염을 앓고 있는 노인 여성 피로 경험의 근거 이론적 접근)

  • Kwon, Young-Eun;Chung, Myung-Sill
    • Journal of muscle and joint health
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    • v.3 no.1
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    • pp.50-62
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    • 1996
  • The purpose of this study was to identify and construct a substantive theory about the experience of fatigue among the female elderly with osteoarthritis. The interviewees were 6 female elderly with osteoarthritis. Of them 3 were admitted General hospital, the remaining 3 didn't admitted hospital. The data were collected through in-depth interviews by the investigators from May 20th, 1995 to June 19th, 1995. The collected data were coded into concepts and categories according to Strauss & Corbin's grounded method. The data thus collected were analyzed immediatly after interviews and fed into next round of interviews until the data collection reaches the saturation point where no additional concepts emerge. The 35 concepts were from analyzing the grounded data. The results of this study were as follows : 'change of the health condition','change of the life pattern', 'physiologic change', 'change of the coping pattern', 'performance of homework', 'activity daily living', 'tireness', 'ache', 'change of general apperance', 'sleep disturbance', 'powerlessness'. 'Physiologic unbalance', 'change of the family dynamics', 'physical imbalance', 'loss of the control', aviodance', 'conversion', 'leaving', 'indifference', 'hesitation', 'the pursue of information and trial', 'the western therapy', 'heat therapy', 'the oriental therapy','exercise', 'weight control', 'support', 'solution', 'being as before', 'adding more'. Six categories emerged from the analysis of ground data. They were as follows : 'stimuli', 'fatigue', 'passive coping', 'active coping', 'disolution', 'remains'. 13 hypothesis were derived from the integration of categories as follows : 1. The stronger the stimulus as perceived by the subjects, the more the fatigue will exrerience. 2. The more severe the fatigue, the more severe the tireness. 3. The more severe the fatigue, the more the hardness. 4. The more severe the fatigue, the more the variability of appear will experience. 5. The more severe the fatigue, the more the pain will experience. 6. The more severe the fatigue, the more the insomnia will experience. 7. The more severe the fatigue, the more the powerless will experience. 8 The more severe the fatigue, the more the psychological unbalance will experience. 9. The more severe the fatigue, the more variability of the family dynamics will experience. 10. The more severe the fatigue, the more the physical unbalance will experience. 11. The more severe the fatigue, the more loss of control will experience. 12. The subjects who experienced the fatigue will be to show passive coping and active coping mechanism.

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A Numerical Study on the Generation and Propagation of Intake Noise in the Reciprocating Engine (엔진 흡기계의 소음발생 및 전파에 관한 수치연구)

  • 김용석;이덕주
    • Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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    • 1996.10a
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    • pp.65-70
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    • 1996
  • 엔진소음을 소음특성에 따라 분류하면 공력소음(Aerodynamic Noise), 연소소음(Combustion Noise), 기계적인 소음(Mechanical Noise)으로 나눌 수 있으며 소음원의 종류에 따라 분류하면 배기계소음(Exhaust System Noise)으로 나눌 수 있으며 소음원의 종류에 따라 분류하면 배기계소음(Exhaust System Noise), 흡기계소음(Intake System Noise), 냉각계소음(Cooling System Noise), 엔진표면소음(Engine System Noise)등으로 분류할 수 있다. 이러한 여러소음중 엔진 내부의 유동에 의한 흡배기계통으로의 소음방출은 자동차 실 내외 소음의 중요한 문제로 대두되는데, 이를 줄이기 위해 그 동안 소음기 등의 서브시스템의 형태와 그 위치조정에 관한 연구가 수행되어 왔다. 그러나 이것이 비용 또는 성능에 영향을 미치므로 본질적인 소음원을 규명해 내는 것이 필요하게 되었다. 흡배기계의 소음은 엔진의 흡입, 배기행 정시 피스톤의 운동에 의해 팽창 및 압축파 형태의 압력파(pressure wave)로 발생하게 되고, 밸브근방에서는 유동의 박리(separation)에 의해 발생하게 된다. 소음기 등의 서브시스템에서도 유동의 박리에 의해 발생하게 되며 특히 배기행정시 발생하는 압력파는 비선형영역에 있게된다. 흡기소음은 배기에 비해 그 크기가 작아서 그동안 등한시 되어왔으나 이것이 소비자의 불평요인으로 작용하므로써 이에 대한 연구도 활발히 수행되어야 한다. Bender, Bramer[1]는 흡배기계 소음의 외부 방사에 관하여 전반적으로 기술하였고 Sierens등[2]은 흡기계에서 1차원 MOC(Method of Characteristics)방법으로 비정상 유동해석을 하고 실험결과와 비교하였다. J.S.Lamancusa 등[3]은 흡기 소음원을 실험을 통해 예측하였고, 흡기소음도 비선형 거동을 보인다고 밝혔다. Yositaka Nishio 등[4]은 새로운 흡기실험장치를 고안하여 공명기(resonator)의 위치 변화에 의한 저소음 흡기계를 설계 초기단계에서부터 적용하려 하였다. 일반적으로 흡배기계의 복잡한 형상 때문에 대부분 실험을 통해 문제를 해결하려 하였고, 수치해석은 피스톤의 운동을 배제한 단순화한 흡배기계의 정상상태 유동해석이 주를 이루어왔다. Taghaui and Dupont 등[5]은 KIVA코드를 사용하여 흡기포트와 연소실 그리고 밸브의 움직임을 동시에 고려한 수치해석을 도입하였다. 하지만 이들이 밸브의 운동을 고려하기 위해 사용한 이동격자는 격자점은 시간에 따라 변화하지만 그 격자의 수가 일정하게 유지되어 있어서 밸브의 완전개폐를 해석할 수가 없다. 강희정[6]은 단일 실린더와 단일 배기밸브를 갖는 문제로 단순화하여 피스톤과 밸브의 움직임을 고려하므로써 배기행정 후 소음이 어떻게 전파해 나가는가를 연구하였다. 본 연구에서도 최소밸브간격과 최대밸브간격 사이에서만 계산이 가능하나 흡기의 경우는 밸브가 닫힐 때 생기는 압력파가 중요하므로 실린더와 밸브사이에 벽면조건을 주어 밸브의 개폐를 모사하였다.

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Role of a Phytotoxin Produced by Fusarium oxysporum f. sp. raphani on Pathogenesis of and Resistance to the Fungus (무 시들음병균이 생산하는 Phytotoxin의 병원성 및 저항성에서 역할)

  • Shim, Sun-Ah;Kim, Jin-Cheol;Jang, Kyoung Soo;Choi, Yong Ho;Kim, Heung Tae;Choi, Gyung Ja
    • Horticultural Science & Technology
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    • v.31 no.5
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    • pp.626-632
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    • 2013
  • In the course of a developing screening method for resistant radish to Fusarium oxysporum f. sp. raphani, we found that the fungus produces phytotoxic compound against Raphanus sativus. The culture filtrate of F. oxysporum f. sp. raphani KR1 represented the strongest phytotoxicity when the fungus was incubated in the malt extract broth with 150 rpm at $25^{\circ}C$ for 14 days. Under bioassay-guided purification, we isolated a substance from liquid culture of F. oxysporum f. sp. raphani KR1, with phytotoxic effect against R. sativus. The compound was identified as fusaric acid by mass and nuclear magnetic resonance spectral analyses. Phytotoxicity of the compound against cruciferous vegetable crops, including radish, cabbage, and broccoli, was investigated. Fusaric acid represented phytotoxicity on radish seedlings by concentration dependant manner. And the phytotoxin demonstrated strong phytotoxicity on the resistant cultivars as well as susceptible cultivars of radish to F. oxysporum f. sp. raphani. In addition, fusaric acid isolated from the fungus also showed a potent phytotoxic efficacy against non-host Brassicaceae crops of the fungus such as cabbage and broccoli. The results demonstrate that fusaric acid produced by F. oxysporum f. sp. raphani is non-host-specific toxin and for screening of resistant radish to the fungal pathogen, spore suspension of the fungus without the phytotoxin has to be used.

Construction of a Microsatellite Marker Database of Commercial Pepper Cultivars (유통 중인 고추 품종에 대한 Microsatellite 마커 Data Base 구축)

  • Kwon, Yong-Sham;Hong, Jee-Hwa;Choi, Keun-Jin
    • Horticultural Science & Technology
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    • v.31 no.5
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    • pp.580-589
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    • 2013
  • This study was carried out to evaluate the suitability of microsatellite markers for varietal identification and genetic relationship of 170 commercial pepper cultivars. The relationship between marker genotypes and 11 pepper cultivars with different morphological traits was also analyzed. Of the 302 pairs of microsatellite primers screened against 11 pepper cultivars, 24 pairs were highly polymorphic in terms of number of alleles. These markers were applied for the construction of DNA profile data base for 170 commercial pepper cultivars. A total of 164 polymorphic amplified fragments were obtained from 24 microsatellite primers. The average polymorphism information content was 0.673 ranging from 0.324 to 0.824. One hundred and sixty four microsatellite alleles were used to calculate Jaccard's distance coefficients using unweighted pair group method. A clustering group of varieties, based on the results of microsatellite analysis, were categorized into 3 major groups corresponding to morphological traits. The phenogram discriminated all varieties by markers genotypes. These microsatellite markers will be useful as a tool for protection of plant breeders' intellectual property rights through variety identification in distinctness, uniformity and stability test.

A Study on the Evacuation Risk of Simultaneous Fires from Exterior (외장재에 의한 동시다발적인 화재의 피난위험성에 관한 연구)

  • Min, Se-Hong
    • Fire Science and Engineering
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    • v.26 no.4
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    • pp.48-54
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    • 2012
  • In order to study on the evacuation risk when connate fires caused by vertical fire spread of the exterior occurs, the egress simulations based on the relevant scenarios has carried out. As a result of it, ASET (permitted evacuation time) was reached in between 550 to 650 seconds in entire floors after vertical smoke spread from fire of combustible exteriors. In particular, ASET was 358 seconds in the first floor, 490 seconds in the six floor and 473 seconds in the tenth floor. In addition, five floors of all levels, the 1st floor, the 6th floor and the 28th floor ~30th floor, show RSET (minimum evacuation time) which is bigger than ASET as evacuation risk. This result presents occupants in high rise buildings with more than 15 floors might not be able to egress of them using staircases due to huge population attempting to evacuate simultaneously. Particularly, 699 people in the upper levels by smoke from the first floor are having difficulty escaping this building since ASET on the first floor adjacent to the ignition point was 358 seconds which is relatively reached fast. Considering a prevention method of the fire and smoke spread, architects have to use non-combustible exterior in the building's facade to be required as an active fire protection system.

The Antioxidant Ability of Grape Seed Extracts (포도씨 추출물의 항산화성)

  • Jang, Jae-Kweon;Han, Ji-Young
    • Korean Journal of Food Science and Technology
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    • v.34 no.3
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    • pp.524-528
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    • 2002
  • The study was carried out to evaluate the antioxidant activity of grape seed extracts by measuring acid value, peroxide value (POV), thiobarbituric acid reactive substances (TBARS value) and electron donating ability by 1,1-dipheny1-2-pycryl hydrazil (DPPH) method. Total phenol content of freeze dried crude solvent extracts increased in the order of ethanol>acetone>hot water. Among extracts, the total phenol content of 70% ethanol extract of grape seed (GSE) was the highest, 51%. Besides the total phenol, the other major components of GSE were crude carbohydrate (29.63%), crude protein (3.38%) and crude lipid (2.84%). The acid values of crude rice bran oil containing GSE or several antioxidants at the concetration of 0.01% were 52.3 for the control, 0.5 for GSE, 2.3 for dibutyl hydroxytoluene (BHT), 45.0 for tertiarybutyl hydroxy quinone (TBHQ), 29.9 for tocopherol and 37.7 for ascorbic acid. The POVs for linoleic acid methyl ester in the presence of 0.01% antioxidants were 1220 meq/kg in control, 55 meq/kg in GSE, 104 meq/kg in BHT, 952 meq/kg in tocopherol and 71 meq/kg in GSE, 37% in BHT, 37% in tocopherol and 52% in ascorbic acid. The electron donating abilities by DPPH in the presence of 0.01% antioxidants were 95.3% in GSE, 75.0% in BHT, 96.3% in tocopherol and 98.2% in ascorbic acid. These results indicated that the antioxidants activities of GSE were significantly higher than those of several antioxidants compared.