• Journal of Korean Society for Atmospheric Environment
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• v.33 no.6
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• pp.593-604
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• 2017

The suspended particulate matter(PM) was measured in subway tunnel of Seoul Line 1 to 9 in order to evaluate the pollution degree and characteristics of the PM in the subway tunnel. Also, to analyze the effect of outdoor aerosol concentration on the PM concentration of subway tunnels, the ambient PM concentration around the subway station was extracted by spatial analysis using $PM_{10}$ data of Seoul air pollution monitoring network. Finally, in order to understand pollution pattern in the Seoul subway tunnels, cluster analysis was performed based on input data set such as PM levels in tunnel, tunnel depth, length, curvature radius, outdoor ambient air pollution levels and so on. The average concentration of $PM_{10}$, $PM_{2.5}$, and $PM_1$ on subway tunnels were $98.0{\pm}37.4$, $78.4{\pm}28.7$, and $56.9{\pm}19.2{\mu}g/m^3$, respectively. As a result of the cluster analysis, tunnels from Seoul subway Line-1 to Line-9 were classified into five classes, and the concentrations and physical properties of the tunnels were compared. This study can provide a method to reduce PM concentration in tunnel for each pollution pattern and provide basic information about air quality control in Seoul subway tunnel.

• Korean Journal of Cognitive Science
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• v.23 no.3
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• pp.367-388
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• 2012

The centennial of Alan Mathison Turing(23 June 1912 - 7 June 1954) is an appropriate occasion on which to assess his profound influence on the development of cognitive science. His contributions to and attitudes toward that field are discussed from the metamathematical perspective. This essay addresses (i)Turing's mathematical analysis of cognition, (ii)universal Turing machines, (iii)the limitations of universal Turing machines, (iv)oracle Turing machine beyond universal Turing machine, and (v)Turing test for cognitive science. Turing was a ground-breaker, eager to move on to new fields. He actually opened wider the scientific windows to the mind. The results show that first, by means of mathematical logic Turing discovered a new bridge between the mind and the physical world. Second, Turing gave a new formal analysis of operations of the mind. Third, Turing investigated oracle Turing machines and connectionist network machines as new models of minds beyond the limitations of his own universal machines. This paper explores why the cognitive scientist would be ever expecting a new Turing Test on the shoulder of Alan Turing.

• IMMUNE NETWORK
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• v.5 no.4
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• pp.193-198
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• 2005

Background: Protease-activated receptor 2 (PAR2) belongs to a family of G protein coupled receptors activated by proteolytic cleavage. Trypsin-like serine proteases interact with PAR2 expressed by a variety of tissues and immune cells. The aim of our study was to investigate whether PAR2 stimulation can lead to the activation of human mac rophages. Methods: PAR2-mediated proliferation of human macrophage cell line THP-1 was measured with MTT assay. We also examined the extracellular regulated kinase (ERK) phosphorylation and cytokine production induced by trypsin and PAR2-agonist using western blot and enzyme-linked immunosorbent assay (ELISA), respectively. Results: Treatment of trypsin or PAR2-activating peptide increased cell proliferation in a dose-dependent manner, and induced the activation of ERK1/2 in THP-1 cells. In addition, trypsin-induced cell proliferation was inhibited by pretreatment of an ERK inhibitor (pD98059) or trypsin inhibitor (SBTI). Moreover, PAR2 activation by trypsin increased the secretion of TNF-${\alpha}$ in THP-1 cells. Conclusion: There results suggest that P AR2 activation by trypsin-like serine proteases can induce cell proliferation through the activation of ERK in human macrophage and that PAR2 may playa crucial role in the cell proliferation and cytokine secretion induced by trypsin-like serine proteases.

• IMMUNE NETWORK
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• v.2 no.4
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• pp.195-201
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• 2002

Background: IgE is closely related to the development of allergies. However, the poor relationship between the specific IgE level and the severity of allergic diseases suggests the possibility of functionally different IgE isoforms. With this in mind, rat basophilic leukemia (RBL)-2H3 activation was analyzed with each type of rat IgE for two parameters, exocytosis and IL-4 mRNA production. RBL-2H3 has been well documented in the rat mucosal mast cell line. Methods: RBL-2H3 cells sensitized with each kind of rat IgE was activated by cross-linking FcRI with B5 (monoclonal anti-rat IgE mouse IgG antibodies). The RBL-2H3 exocytosis was measured by analyzing the ${\beta}$-hexosaminidase level, and the level of IL-4 mRNA synthesis was analyzed using semiquantitative RT-PCR. Rat IgE, which was produced by a parasite infection (REP), was prepared using either Paragonimus westermani metacercariae (REP-PW) or Anisakis simplex third stage larvae (REP-AS). A rat IgE prototype of IR162 was prepared by a peritoneal injection of immunocytoma. Results: The level of exocytosis showed a linear relationship with the rat IgE concentration when REP-PW or REP-AS was applied. However, it exhibited a biphasic response with IR162. In addition, the time course of heating at $56^{\circ}C$ illustrated the similarity between REP-PW and REP-AS, which differed from that of IR162. In contrast, the level of IL-4 mRNA synthesis in the RBL-2H3 cells with IR162 was comparable to that of either REP-PW or REP-AS. Conclusion: These results suggest that functionally different rat IgE isoforms exists in RBL-2H3 exocytosis.

• IMMUNE NETWORK
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• v.3 no.2
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• pp.118-125
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• 2003

Background: Disialoganglioside GD2 is a tumor-associated antigen that is overexpressed on tumor cells of neuroectodermal origin, such as melanoma and neuroblastoma. Anti-idiotypic antibodies that mimic GD2 may induce more effective immune responses than GD2 antigen itself, because they are protein antigens and are known to be able to break immune tolerance. In this study, to explore the potential of anti-idiotypic antibodies as tumor vaccines, the ability of anti-idiotypic antibodies (Ab2) to induce anti-anti-idiotypic antibodies (Ab3) that bind to the original antigen GD2 was investigated. Methods: Six monoclonal anti-idiotypic antibodies (1A8, 1G5, 2B6, 3A4, 3D6, 3H9) to monoclonal antibody M2058, which is a monoclonal antibody to GD2, were produced in mice. Three (1A8, 3A4, 3H9) of them were selected based on their ability to inhibit the binding of Ab1 to D142.34 (murine melanoma cell expressing GD2). These 3 different Ab2 were injected into rabbits, and rabbit Ab3 induced by each of them were characterized. Results: Ab3-containing sera from two rabbits immunized with 1A8, 3A4, or 3H9 bound significantly (P<0.05) to D142.34 but not to B78.96 (GD2-negative cell), and bound significantly (P<0.05) to isolated GD2 but not to GD1a. Ab3-containing sera from two rabbits immunized with 3A4 or 3H9 inhibited significantly (P<0.05) the binding of Ab1 M2058 to D142.34, and inhibited significantly (P<0.05) the binding of Ab1 M2058 to the Ab2. Conclusion: These results suggest that anti-idiotypic antibodies 3A4 and 3H9 have a potential to be used as vaccines against tumors expressing GD2 by inducing GD2-specific antibodies (Ab3).

• The Bulletin of The Korean Astronomical Society
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• v.36 no.2
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• pp.122.2-122.2
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• 2011

For more than a decade, NEA (Near-Earth Asteroid) survey teams equipped with 1 meter-class telescopes discovered thousands of NEAs in the northern sky. As of August 2011, some 8,200 NEAs have been cataloged, yet only five percent of them has been investigated for their physical and chemical properties. In order to improve current situation, we propose a deep ecliptic survey utilizing KMTNet, for detection and characterization of NEAs in the southern sky. Thanks to the wide-field capability (four square degrees) of the telescopes, we will be able to considerably expand the search volume carrying out precision photometry down to 21.5th magnitude. We plan to focus our survey on opposition and two "sweet spots" in the ecliptic belt. Since SDSS colors characterize mineralogical properties of NEAs, g', r', i', z' filters will be employed. Based on the round-the-clock observation, we will study their rotational properties; for multiple systems, mass, density and other physical parameters can be obtained. We plan to maintain a dedicated database of the physical and mineralogical properties of NEAs. With this archive, it is expected that our understanding on the population will see a drastic change. We also plan to participate in the GAIA Follow-Up Network for ground based observation of the Solar System Objects (GAIA-FUN-SSO). The follow- up astrometry will be performed upon alerts issued by the GAIA-FUN-SSO Central Node in France.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.31 no.3D
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• pp.355-361
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• 2011

In order to properly evaluate ITS services exposed in SMART Highway project, a confident dynamic origin-destination (OD) is inevitably needed. This paper used WAVE communication information as a part of call and response (C&R) communication which constitutes core part of the technology for constructing OD. This information includes node information and vehicle information (e.g., latitude and longitude) as well as trajectory data and sample path volume date calculated using node information and vehicle information. A procedure developed to construct a dynamic OD and to validate OD is consist of 1) making toy network and one-hour 00 (random distribution), 2) collecting link information and vehicle information, 3) constructing five-minute OD, and 4) validating estimated OD result using traffic volume and travel time simultaneously. The constructed OD is about 84.79% correct within less than 20% error range for 15min traffic volume, and about 85.42%, within less than 20% error rate of 15 min travel time. Some limitations and future research agenda have also been discussed.

• Journal of the Korean association of regional geographers
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• v.4 no.2
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• pp.65-77
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• 1998

One of the fundamental, important preconditions for effective teaching of geography is to collect a variety of picture data available for class and to manage the data systematically. The purpose of this study is to present one method about how to supply basic picture data available for class of Korean geography for the high school program to teachers in service and how to collect, manage and utilize the data. A total of 233 picture data related to contents of the textbook of Korean Geography have been gathered through this study, and a database has been constructed for the data. Directories were generated for individual units of the textbook, and the collected picture data was stored in the image file of each directory. This data was recorded in a CD and attached as an appendix. Since the primary purpose of this study is to suggest one method, the picture data in a database for the present study is just a fraction of lots of data available for class of Korean geography. If the user persistently enlarges and manages data based on the results of this study, the data will become a good instructional aid. The picture data can be printed over the transparent film and used for class by using the overhead protector (OHP), or it can be also used as a remote self-study tool through the computer telecommunications network (e.g., LAN or INTERNET. etc,). Most desirable, however, is to develop teachers' own method by taking account of separate units of the textbook or diverse educational environments.

• International Journal of Contents
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• v.17 no.1
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• pp.37-53
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• 2021

With the advent of the 5G era, smart phones and communications network technology have progressed, and mobile short video of people's life can be made, Of the new tools of communication, at present, China's social short video industry has shown rapid development, and the most representative of the short video app is Douyin (international version: Tiktok). Under the background of Uses and Gratifications Theory, this study discusse the relationship between Douyin users' preference degree, use motivation, use satisfaction and attention intention. This study divides the content of Douyin video into 10 categories, selects the form of an online questionnaire survey, uses SPSS software to conduct quantitative analysis of 202 questionnaires after screening, and finally draws the following conclusions: (1) The content preference degree of Douyin short video (the high group and low group) is different in users' use motivation, users' satisfaction degree and users' attention intention. ALL results are within the range of statistical significance.(2) Douyin users' video content preference degree has a positive impact on users' use motivation, users' satisfaction degree, and users' attention intention. (3) Douyin users' motivation has a positive impact on users' satisfaction and user' attention intention. (4) Douyin users' satisfaction degree has a positive impact on users' attention intention. Based on the research results, we suggest that Douyin platform pushes videos according to users' preferences. In addition, as the preference degree has an impact on users' motivation, satisfaction degree and attention intention of using the platform, it is important that the platform's focus should to pay attention to the preference degree of users. Collecting users' preferences at the early stage of users' entering the platform is a good way to learn from, and doing a good job of big data collection and management in the later operation.

• The Journal of the Convergence on Culture Technology
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• v.7 no.3
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• pp.571-576
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• 2021

This study was carried out to overcome the problems of the existing fitness business and to build a fitness system that can meet the increased demand in the Corona situation. As a platform technology for non-face-to-face fitness edutainment service, it is a next-generation fitness exercise device that can use various body parts and synchronize network-type information. By synchronizing the exercise information of the fitness equipment, it was composed of learning contents through MR-based avatars. A quantified result was derived from examining the applicability of the customized evaluation system through momentum analysis with A.I analysis applying the LSTM-based algorithm according to the cumulative exercise effect of the user. It is a motion capture and 3D visualization fitness program for the application of systematic exercise techniques through academic experts, and it is judged that it will contribute to the improvement of the user's fitness knowledge and exercise ability.