• 한국융합학회논문지
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• 제9권5호
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• pp.77-83
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• 2018

국민건강영양조사 제 5기 1 2차년도에 참여한 남성과 여성을 대상으로 연령에 따른 요추 및 대퇴골부위의 최대 골밀도 변화와 골 소실률의 변화 양상을 알아보고자 시도 하였다. 척추와 대퇴부 부위의 골밀도 차이는 분산분석을 이용하였고, 연령에 따른 골밀도의 변화는 Cubic regression을 사용하여 분석하였다. 연구결과, 남성에서의 요추, 대퇴골 부위의 최대 골밀도는 20-24세였으며, 요추에서의 골소실률은 75-79세에서 대퇴부에서는 80세 이상에서 골 소실률이 가장 높았다. 여성에서는 요추, 대퇴골 부위의 최대 골밀도는 40-44세였으며, 요추에서의 골소실률은 70세 이상에서 대퇴부에서는 75-79세, 80세 이상, 55-59세 순으로 골 소실률이 높았다. 따라서, 남성에서는 75세 이상에서 골다공증 검사율을 늘리는 방안을 모색하고, 여성에서는 50대 이후에서 폐경과 관련해서 골다공증의 관리 전략을 짜는 것이 필요할 것이다.

• 대한예방한의학회지
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• 제12권3호
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• pp.129-139
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• 2008

The purpose of this study was to investigate the effect of aqua exercise on women 50 years of age or older with knee degenerative arthritis, and then examining the therapeutic value of aqua exercise in degenerative arthritis of the knee. The subjects of the study were 115 residents 50 years of age or older who had been diagnosed as degenerative arthritis of the knee by doctors from medical institutions and applied for the aqua exercise program in the Public Health Care Center in Suseong-gu in 2006 and 2007. Experiments were conducted to all the subjects with the application of the 8-week aqua exercise program (2 times a week, 50 minutes a time), designed in the study, and the differences before and after the aqua exercise were compared through questionnaires for measuring the state of the body such as the knee extension angles, weight, body fat, and abdominal obesity. The data was analyzed by t-test and the Wilcoxon method through SPSS 14.0 and the statistical significance level ${\alpha}$ was set at 0.05 and 0.01. The results of the study are as the following. First, In comparison of before and after the aqua exercise, there was improvement in the extension angle of the right knee(p<0.01), while there was some improvement in the extension angle of the left knee, it was not significant. Second, In comparison of before and after the aqua exercise there were statistically significant differences in weight(p<0.05), body fat ratio, and abdominal obesity(p<0.01). The results of this study showed that the aqua exercise program to female patients with knee degenerative arthritis significantly increased the extension angle of the knee. Therefore it is thought that aqua exercise is an effective meditating method to improve their symptoms of female patients 50 years of age or older

• 지역사회간호학회지
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• 제32권1호
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• pp.95-106
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• 2021

Purpose: The purpose of this study is to investigate the association between unmet healthcare needs due to financial reasons and catastrophic health expenditures. Methods: This study used secondary data from the 2014~2015 Korean Health Panel survey. The subjects of this study were 21,495 people aged 20 or older, and of them, there were 16,227 people aged 20 to 64 and 5,268 people aged 65 or older, which were surveyed between 2014 and 2015. The association between unmet healthcare needs due to financial reasons and catastrophic health expenditures was analyzed through logistic regression. Results: In 2015, 1.7% of people aged 20~64 years and 7.9% of those aged 65 or older experienced unmet healthcare needs due to financial reasons. In the 20~64 age group, people who repeatedly experienced catastrophic health expenditures (=10%,=20%) were less likely to experience unmet healthcare needs due to financial reasons than those who did not experience catastrophic health expenditures for two years (OR=0.50, OR=0.41). However, in the 65-or-older group, people who repeatedly experienced catastrophic health expenditures (=20%) were more likely to experience unmet healthcare needs due to financial reasons than those who did not experience catastrophic health expenditures for two years (OR=1.68). Conclusion: A greater percentage of the elderly repeatedly faced both catastrophic health expenditures and unmet healthcare needs due to financial reasons compared to the non-elderly.

• Asian Pacific Journal of Cancer Prevention
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• 제17권4호
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• pp.2285-2289
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• 2016

Background: Epstein-Barr virus (EBV) positive diffuse large B-cell lymphoma (DLBCL) of the elderly is an entity introduced in the latest WHO classification of lymphoid tumors and defined in patients older than 50 years without prior lymphoma or immunodeficiency. However, recently it has also been seen in patients under 50. There is thus debate as to whether these are separate entities. Materials and Methods: In this retrospective study, we analyzed de novo DLBCL admitted to our institute over a period of two years. Clinical data included age, sex, nodal and extranodal presentation. The results of an immunohistochemistry (IHC) panel were also reviewed. IHC findings were mainly used to sub-classify DLBCL as germinal center vs. non germinal center types. IHC for identification of LMP-1 (latent membrane protein) and in situ hybridization for detection of EBV-encoded RNA (EBER) was performed. EBV prevalence, clinical data and IHC findings were compared between patients under and over 50 years of age. Results: Out of 95 DLBCL, 11.6% were EBV positive (7.5% and 14.5% in the young and old groups). We did not find any significant differences in IHC subclasses and clinical data between EBV positive DLBCL (EBV+DLBCL) of young and old groups. Conclusions: EBV+DLBCL are not exclusive to patients older than 50 years. With regard to clinical data as well as IHC subclasses, no differences were evident between EBV+DLBCL of young and old groups. Our suggestion is to eliminate any cut off age for EBV+DLBCL.

• 정보관리학회지
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• 제33권4호
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• pp.59-76
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• 2016

본 연구의 목적은 지역정보화의 측면에서 장노년층이 인지하는 정보화교육의 유용성을 분석하는 것이다. 본 연구의 목적을 달성하기 위하여 데이터 수집은 대구지역에 거주하고 있으며 인터넷 사용 경험이 있는 만50세 이상을 대상으로 설문조사와 인터뷰를 통하여 이루어졌다. 수집된 데이터 중 311명의 유효한 응답자 데이터를 정보화교육 참여경험의 유무에 따라 두 집단으로 구분하여 정보화교육의 유용성을 구조방정식으로 분석하였다. 분석결과 두 집단 모두 정보화교육의 유용성은 '정보활용 편의성', '정보활용 유용성', 그리고 '삶의 만족감'에 긍정적인 영향을 미치는 것으로 나타났다. 또한 두 집단 모두 '정보활용 편의성'은 '삶의 만족감'에 긍정적인 영향을 미치는 것으로 나타났으나, '정보활용 유용성'과 '삶의 만족감'은 통계적으로 유의미한 수준은 나타나지 않았다.

• Archives of Plastic Surgery
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• 제44권1호
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• pp.65-71
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• 2017

Background This study evaluated dynamic changes in eyebrow position related to aging. Methods Female participants were recruited and separated into two groups aged 20-30 years (the younger group, n=20; mean age, 24.8 years) and 50-70 years (the older group, n=20; mean age, 55.8 years). Photogrammetry was used to determine the eyebrow position at the medial canthus (MC), lateral limbus, lateral canthus, and lateral end point (EP) for 6 actions: smooth opening (the reference action) and closing of the eye, forward gaze, maximum opening and closing of the eye, and maximum frown. Videos were also recorded. Results No differences in eyebrow position were detected at the MC when opening or closing the eyes smoothly, gazing straight ahead, or closing the eyes maximally. For all 6 actions, the position of the lateral EP in the older group was significantly lower than in the younger group (P=0.003), and the smallest degree of vertical movement at this point was found in both age groups (P<0.001). Vertical movement at the 4 landmarks of the eyebrows decreased with aging. Conclusions Eyebrow position was unchanged at the MC with aging, except at maximal eye opening and maximal frown. No differences in eyebrow position were observed between the younger and older groups when eyes were maximally closed, except at the EP. It is important to focus on correction of the lateral EP for periorbital rejuvenation.

• Infection and chemotherapy
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• 제50권4호
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• pp.301-310
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• 2018

Backgroud: Influenza vaccination is recommended for adults aged ${\geq}65$ years as they are at high risk of significant morbidity and mortality. This open-label, multicenter, post-marketing surveillance study assessed the safety of the MF59-adjuvanted trivalent inactivated subunit influenza vaccine, which is marketed as $FLUAD^{(R)}$ and $VANTAFLU^{(R)}$, in South Korean subjects aged ${\geq}65$ years. Materials and Methods: Solicited local and systemic adverse events (AEs) were collected from day 1 to 4 of the study. All unsolicited AEs and serious AEs (SAEs) were recorded from day 1 until study termination (day 29). Results: Of the 770 subjects enrolled ($FLUAD^{(R)}$, n = 389; $VANTAFLU^{(R)}$, n = 381), 39% overall experienced any solicited AE. Local AEs were reported by 33% of subjects overall; with the most common events being injection-site pain (30%) and tenderness (27%). Systemic AEs were reported by 19% of subjects overall with the most common events being myalgia (11%) and fatigue (8%). Conclusion: These results show that the MF59-adjuvanted influenza vaccine known as $FLUAD^{(R)}$ or $VANTAFLU^{(R)}$ had acceptable safety profiles in older adults (aged ${\geq}65$ years) in South Korea.

• 치위생과학회지
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• 제23권2호
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• pp.142-153
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• 2023

Background: Cognitive impairment has been reported to be closely associated with poor oral health, and the relationship is bidirectional, as older adults with poor oral health and chewing function are at a higher risk of cognitive decline (CD). This cross-sectional study aimed to determine whether masticatory discomfort in Korean elderly increases the risk of daily living difficulty (DLD) related to CD and whether there is a difference in risk according to gender and age. Methods: The data used were obtained from the Korean Community Health Survey (2019). The final analysis included 22,154 people aged 65 years and older who completed the survey and responded to all items on the variables used in the study. Chi-square test, trend test, and complex sample logistic regression were performed for statistical analysis, to clarify the purpose of this study. Results: As masticatory discomfort increased, the elderly's DLD tended to increase (p-for trend, p<0.001). For logistic regression, adjusting for all covariates, participants who reported masticatory discomfort as "discomfort" (adjusted odds ratio [AOR]=2.45, 95% confidence interval [CI]=2.11~3.50) and "severe discomfort" (AOR=2.95, 95% CI=2.49~3.50) had a more than a two-fold increased risk of CD-related DLD compared to participants who reported "no discomfort at all." In age-stratified analyses, elderly men aged 75~84 years and elderly women aged 65~74 years had the highest risk of developing CD-related DLD. Conclusion: Oral care interventions to improve masticatory function in older adults may slow CD and improve CD-related DLD. We hope that this study will raise awareness among caregivers and clinical professionals regarding the importance of oral care for older adults with CD.

• 융합정보논문지
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• 제9권6호
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• pp.194-201
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• 2019

서울지역의 호흡기질환으로 입원한 환자를 대상으로 미세먼지 노출에 대한 건강영향을 평가하였다. 건강보험공단의 2002-2010년 동안 표본코호트의 만성폐쇄성 폐 질환(COPD), 천식 및 폐렴과 같은 호흡기 질환으로 입원한 13,974명의 환자를 대상자로 하였다. 추적관찰 기간동안 미세먼지 농도가 50ug/m3 이상에서 10ug/m3 증가할 때 15세 미만의 연령층에서는 1.38%, 65세 이상의 연령층에서는 1.62%, 75세 이상 연령층에서는 2.87% 호흡기질환으로 입원이 증가하였고, 폐렴환자는 1.50%, COPD 환자는 1.51%, 폐렴 및 천식환자는 1.55% 입원이 증가하였다. 또한 미세먼지가 80ug/m3 이상에서는 65세 이상 연령층에서 3.71%, 75세 이상 연령층에서 4.25% 입원환자가 증가하였다. 높은 미세먼지농도와 호흡기 질환으로 입원한 환자들과, 특히 노인에서 관련성이 높게 나타났다. 이미 호흡기 질환이 있었던 사람들, 특히 나이가 많은 환자는 고농도의 미세먼지에 노출되지 않도록 주의해야 한다.

• Asian Pacific Journal of Cancer Prevention
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• 제13권9호
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• pp.4577-4580
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• 2012

Diagnostic and therapeutic strategies of prostate cancer may largely influenced by patients' age at presentation. This study is aimed to evaluate the characteristics, diagnostic and treatment strategies in prostate cancer patients in our centres. A cross-sectional analytic study of prostate cancer data in two main referral cancer centres, Cipto Mangunkusumo General Hospital and Dharmais National Cancer Centre from 1995-2010, was therefore performed. Patients were divided into 2 sub-populations; below 60 years (younger patients) and 75 years old and above (older patients). PSA levels, diagnostic modalities, Gleason score and therapeutic options were analysed for both and compared using bivariate analysis. 152 patients were <60 years and 210 were ${\geq}75$ years. There was no statistical difference in mean PSA level (797.9ng/mL vs 345.3 ng/mL, respectively; p>0.05) and diagnosis was made by biopsy in majority of patients in both groups (68.2% and 71.6% in younger and older groups respectively). Most presented with an advanced disease stage (65.1% and 66.0%, respectively) and there was no statistically significant difference in mean Gleason scores f (8.1 vs 7.7; p>0.05). Primary androgen deprivation therapy (PADT) was the main treatment for overall patients (48.0% and 50.7%, respectively). Radiotherapy and radical prostatectomy are the main therapeutic modalities for younger patients with local and locally advanced disease (39.6% and 35.4% respectively), while the majority of older patients with the same disease stage were treated with radiotherapy and PADT (45.8% and 39.0% respectively). Differences observed in treatment modalities were statistically significant (p<0.0003). We conclude that there is no difference in disease clinical aggressiveness of the two groups but significant differences were observed in therapeutic strategies utilised with younger and older patients.