• Title/Summary/Keyword: 50 Years

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Detection and Prognostic Analysis of Serum Protein Expression in Esophageal Squamous Cell Cancer

  • Jiang, Hong;Wang, Xiao-Hong;Yu, Xin-Min;Zheng, Zhi-Guo
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.4
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    • pp.1579-1582
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    • 2012
  • Objective: To assess differences in serum proteins in esophageal squamous cell carcinoma patients. Methods: 144 esophageal squamous cell carcinoma patients and 50 healthy volunteers were included in this study, with surface-enhanced laser desorption-ionization time-of-flight mass spectrometry and weak cation exchange magnetic beads. Follow-up allowed the relations between serum proteins and prognosis to be analyzed. Results: A total of 93 protein peaks were detected (molecular weight range: 1500-30000), 10 demonstrating statistically significant differences. There were no differences in protein peaks between 92 patients with a survival more than 2 years and 52 patients with survival less than 2 years. There were two significantly different protein peaks between 45 stage II patients with a survival more than 2 years and 14 stage II patients with survival less than 2 years. There was one significantly different protein peak between 22 stage III patients with a survival more than 2 years and 29 stage III patients with survival less than 2 years. Conclusion: Differences of serum proteins in esophageal squamous cell carcinoma are related to prognosis of patients. The protein fingerprint can be helpful for clinical diagnosis and treatment.

The Energy Flow and Mineral Cycles in a Zoysia japonica and a Miscanthus sinensis Ecosystem on Mt. Kwanak 11. The Cycles of Al (관악산의 잔디와 억새 생태계에 있어서 에너지 흐름과 무기물의 순환 11.알루미늄의 순환)

  • 심규철;장남기
    • Asian Journal of Turfgrass Science
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    • v.11 no.4
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    • pp.303-309
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    • 1997
  • The investigation was cycle of aluminum of surface soil elements in dynamic grassland ecosystems at a steady state in a Zoysia japonica and a Miscanthus sinensis ecosystem in Mt. Kwanak, Korea. Average amounts of total storage for aluminum in Z japonica and M. sinensis grasslands were 8,426mg /$m^2$ and 7,849mg /$m^2$ respectively. Decay constants estimated on the base of experimental and mathematical model, were 0.04 in Z japonica grassland, and 0.08 in M. sinensis grassland. Half time to decay aluminum of litter soils were 17.33 years in Z japonica grass-land, and 8.66 years in Al. sinensis grassland. 95% decay times in Z japonica, and in M. sinensis grassland were 75.0 years and 35.0 years respectively. Needed times to lose almost all of elements in Z japonica and M. sinensis grassland were 125.0 years, and 62.50 years respectively. The metals were losed more rapidly in M. sinensis than in Z japonica grassland. The cycle of aluminum was investigated to be related with soil acidity. Key words: Cycle of aluminum, Zoysia japonica. Miscanthus sinensis, Mt. Kwanak, Decay constants, Soil acidity.

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The Wear Rate and Survivorship in Total Hip Arthroplasty Using a Third-generation Ceramic Head on a Conventional Polyethylene Liner: A Minimum of 15-year Follow-up

  • Bum-Jin Shim;Sung-Jin Park;Chan Ho Park
    • Hip & pelvis
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    • v.34 no.2
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    • pp.115-121
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    • 2022
  • Purpose: The purpose of this study was to evaluate the wear and survival rates of third-generation ceramic heads on a conventional ultra-high molecular weight polyethylene liner. Materials and Methods: A total of 160 hips (147 patients with a mean age of 55.9 years) who underwent total hip arthroplasty using the third-generation ceramic head on a conventional polyethylene liner from March 1998 to August 2003 were reviewed retrospectively. Evaluation of the wear rate for 56 hips (49 patients) followed-up for at least 15 years was performed using the PolyWare program version 8 (Draftware Developers, USA). The Kaplan-Meier survivorship was also evaluated. Results: Linear wear and volumetric wear rates were 0.11±0.47 mm/year and 32.75±24.50 mm3/year, respectively. Nine revisions were performed during the follow-up period because of cup or stem loosening. The Kaplan-Meier survival rate, using cup revision or total revision total hip arthroplasty (THA) as the endpoint of analysis, was 93.7% at 15 years and 73.6% at 20 years. Conclusion: Because all revisions were performed between 15 and 20 years in our study, surgeons should pay greater attention to patients who underwent THA with ceramic-on-polyethylene bearing from 15 years postoperatively. Contemporary alumina ceramic on highly cross-linked polyethylene could certainly be a good alternative bearing couple providing better longevity.

Emergence Ecology of Japanese Pine Sawyer, Monochamus alternatus (Coleoptera: Cerambycidae), a Vector of Pinewood Nematode, Bursaphelenchus xylophilus (소나무재선충의 매개충인 솔수염하늘소 성충의 우화 생태)

  • 김동수;이상명;정영진;최광식;문일성;박정규
    • Korean journal of applied entomology
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    • v.42 no.4
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    • pp.307-313
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    • 2003
  • Japanese pine sawyer, Monochamus alternatus, is a primary vector of pinewood nematode, Bursaphelenchus xylophilus in Korea. Emergence characteristics of the adults were studied in Jinju, Korea using dead pine logs in which the larvae of the sawyer overwintered from 1999 to 2002. Emergence data showed that the adults began to emerge out of the logs in sunny place from May the 15th in average of the four years. Cumulative emergence ratio (CER) reached at 50% at mid-June, and the emergence terminated by early or late July depending on years. In shady place, however,50% CER was reached 17 days later than in sunny place. The 50% CER of males reached 1 to 4 days earlier than that of females depending on years. Of the adults emerged from the logs collected from February to April in 2001, 97.6% was univoltine, and the rest was biennial which emerged from May to July of the next year. Female and male adults emerged throughout 24 hours; 32.3% of the total adults emerged from 8 to 12 a.m. It took 68.0 seconds for the adults to escape from pine logs.

A Study on the Progression and Prevalence of Myopia according to Age for the Last Five Years : from 2008 to 2012 (최근 5년간 연령에 따른 근시 유병률 진행에 관한 연구 : 2008년에서 2012년 중심으로)

  • Lee, Wan-Seok;Ye, Ki-Hun;Shin, Bum-Joo
    • Journal of Korean Ophthalmic Optics Society
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    • v.19 no.1
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    • pp.121-133
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    • 2014
  • Purpose: In this study, we analyzed the progression and prevalence of myopia according to age for the last five years. Methods: We have done a comparative analysis of the progression and prevalence of myopia with the Korean National Health and Nutrition Examination Survey document from 2008 to 2012. Results: According to classification of myopia by age group for the last five years, the prevalence of low myopia was 25.5% for 5-11ages group, 25.1% for 12-18ages, 27.3% for 19-29ages, 30.7% for 30-39ages, 29.6% for 40-49ages, 19.2% for 50-59ages, 11.8% for 60-69ages, and 20.2% for over 70ages respectively. The prevalence of moderate myopia was 21.7% for 5-11ages group, 43.6% for 12-18ages, 36.2% for 19-29ages, 30.0% for 30-39ages, 20.4% for 40-49ages, 9.9% for 50-59ages, 5.2% for 60-69ages, and 7.6% for over 70ages respectively. The prevalence of high myopia was 2.1% for 5-11ages group, 11.7% for 12-18ages, 11.5% for 19-29ages, 6.9% for 30-39ages, 5.6% for 40-49ages, 1.9% for 50-59ages, 1.5% for 60-69ages, and 1.0% for over 70ages respectively. Conclusions: We must recognize an importance to the increase of the progression and prevalence of myopia, so it is necessary to provide a social interest in prevention of deteriorating vision and eye health welfare.

The 50-year history of the Korean Society of Plant Taxonomists: Professional manpower training and research activity (한국식물분류학회 50년사: 인력양성과 연구활동)

  • LEE, Nam Sook
    • Korean Journal of Plant Taxonomy
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    • v.48 no.4
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    • pp.363-369
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    • 2018
  • Since the establishment of the Korean Society of Plant Taxonomists (KSPT) on Dec. 13, 1968, the professional manpower training and research activities have been analyzed. The survey method was based on the homepage of the KSPT and the Korean J. Pl. Taxon, and on data provided by each university about professional manpower. Over the past 50 years, a total of 680 specialists in plant taxonomy have been trained, consisting of 537 master's degree holders (274 males, 263 females) from 30 universities and 143 PhDs (97 males, 46 females) from 26 universities, and the number has increased significantly since 1998. With regard to changes in the field of research over the last ten years, revision papers were the most common in the period of 1988-1997 (72%), but this rate has decreased to 51% over the last ten years, while the number of unrecorded papers has increased to 28%. In the 629 revision papers on taxa, 49% of the taxa belong to Asteraceae, Ranunculaceae, Cyperaceae, Liliaceae, Rosaceae, Fabaceae, Apiaceae, Lamiaceae, Orchidaceae, Oleaceae, Euphorbiaceae, Polygonaceae, and Amaryllidaceae. With regard to changes in research methods, the number of morphological papers increased from 6% to 51%, while pollen papers have decreased from a rate of 20% to only 2%. Chromosome studies account for 3-4%, chemotaxonomic studies 2%, and DNA studies remain low at 3-16%. The percentage of papers in English now stands at 43%, mainly due to the increased number of papers on unrecorded species.

Ecological Characteristics of Phoxinus phoxinus (Cyprinidae) at the Spring Water in Eocheon Stream, Korea (어천 용천수에 서식하는 연준모치 Phoxinus phoxinus (Cyprinidae)의 생태 특성)

  • Byeon, Hwa-Keun
    • Korean Journal of Environment and Ecology
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    • v.33 no.3
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    • pp.256-265
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    • 2019
  • We investigated the ecological characteristics of Phoxinus phoxinus in the spring water in Eocheon stream from January to December 2016. The water temperature was $9.7{\sim}14.3^{\circ}C$ and remained below $15^{\circ}C$ throughout the year. The fishes cohabiting with minnow were Rhynchocypris kumgangensis (70.14%), Cottus koreanus (13.63%), Rhynchocypris oxycephalus (3.16%), Oncorhynchus mykiss (0.97%), Zacco koreanus (0.49%), and Iksookimia koreensis (0.24%). The sex ratio of female to male was 1:0.86. The frequency analysis of total length indicated that the fishes with the total length of 30 - 50 mm were one year old, those of 50 - 65 mm were two years old, those of 65 - 75 mm were three years old, and those of 75 mm or more were four years old. The sexually mature fishes were 50 mm or longer for female and 60 mm or longer for male. The spawning season was from April to July, and the water temperature was $12.3-14.3^{\circ}C$ during the period. The prosperous spawning season was from June to July, and the water temperature was $13.8-4.3^{\circ}C$ during the period. The average number of eggs in the ovaries was 508 per matured female, and the matured eggs were yellowish and spherical with a mean diameter of $1.58{\pm}0.13mm$. The length-weight correlation of P. phoxinus was $BW=0.000007TL^{3.09}$ with the constant a as 0.000007 and the parameter b as 3.09. The condition factor (K) was 0.99 (0.76 - 1.32) in average.

Ecological Characteristics of Microphysogobio yaluensis in Dugye Stream of Geum River Basin, Korea (금강지류 두계천에 서식하는 돌마자(Microphysogobio yaluensis)의 생태 특성)

  • Byeon, Hwa-Keun
    • Korean Journal of Environment and Ecology
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    • v.36 no.4
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    • pp.381-389
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    • 2022
  • This study investigated the ecological characteristics of Microphysogobio yaluensis at Dugye Stream of Geum River basin from January to December 2021. The river bed structure of this species' habitat was rich in pebbles and gravel. The water depth ranged from 12 to 85 cm with an average of 23 cm, which was shallow. The stream velocity was rapid at 1.03±0.34(0.72-1.47) m/sec. The ratio of females to males was 1:0.86. The age according to the total length-frequency distribution as of summer (June, July) indicated that the group with less than 50 mm (30.4-49 mm) in total length was one year old, the group with 50-69 mm was two years old, and the group over 70-92 mm was three years old. Both male and female fish sexually matured at 50 mm long and two years old in June and July. The spawning season was from July to August, and the water temperature was between 25.8℃ and 28.2℃ during the period. The prosperous spawning season was July. The matured eggs were yellowish and spherical with a mean diameter of 0.52±0.16 (0.33-0.77) mm, and the average number of eggs found in the ovaries of mature female fish was 2,593 (1,343-4,672). As for the food of M. yaluensis, only attached algae, which grow by attaching to stones and gravel of the stream rapids, were identified. The feeding habit of M. yaluensis was reported to be herbivorous, ingesting Cyanophyta, Chlorophyta and Bacillariophya. Also, the species belonging to Bacillariophya and Chlorophyta were abundant in Dugye Stream.

Epidemiologic Characteristics of Death in Breast Cancer Patients and Health Promotion Plans : Using Korean Cancer Registry data (유방암 환자 사망의 역학적 특성과 건강증진 방안 : 국가 암등록 자료를 이용하여)

  • Young-Hee Nam
    • The Journal of Korean Society for School & Community Health Education
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    • v.24 no.1
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    • pp.1-15
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    • 2023
  • Objectives: The purpose of this study was to identify the major influencing factors of breast cancer death and to suggest policy measures to promote the health of breast cancer patients. Methods: The method of this study performed statistical analysis by applying weights to 2,300 cases of breast cancer registration statistics in Korea collected in 2018 due to the relatively small number of mortality data compared to survival. Statistical processing of the collected data was analyzed using SPSS 26.0. Results: The epidemiologic characteristics of death in breast cancer patients were 31.8% in those aged 70 years or older, and the mortality rate was 5.25 times higher in patients aged 70 years or older than those aged 39 years or younger. The anatomical site code was 36.4% in C50.4~C50.6, and the mortality rate was 1.82 times higher in C50.4~C50.6 than in C50.0~C50.1. The tumor size was 40.4% and larger than 4cm, and the mortality rate was 4.53 times higher in tumors larger than 4cm than those smaller than 1cm. The degree of differentiation was 13.9% in the poorly differentiated group, and the mortality rate was 4.38 times higher in the poorly differentiated group than in the highly differentiated group. In the hormone receptor test, non-triple negative cases were 59.6%, and the mortality rate was 0.57 times lower in non-triple negative cases than in triple negative cases. As for lymph node involvement, the presence or absence of lymph node involvement was 78.8%, and the mortality rate with lymph node involvement was 1.36 times higher than that without lymph node involvement. The survival period of 13 to 24 months was the highest at 26.5%, and the average survival period was 25.68 months (±14.830). Conclusion: A policy to advance the timing of national health examinations for early detection of breast cancer is necessary. In addition, a bill for the mandatory placement of health educators in medical institutions for patients with special diseases such as breast cancer should be prepared.

Depositions of Egg Capsules by Female Shell Heights and Comparisons of Sizes at 50% of Group Sexual Maturities of the Female Rapa Whelk Rapana venosa in Three Different Salinity Concentration Regions

  • Lee, Il Ho;Chung, Ee-Yung;Son, Pal Won;Lee, Ki-Young
    • The Korean Journal of Malacology
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    • v.30 no.2
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    • pp.139-153
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    • 2014
  • We investigated fecundities in egg capsules and sizes at 50% of group sexual maturities in female Rapana venosa in three different salinity concentration regions (S-1, S-2, and S-3). In three different salinities, egg capsule heights, the number of egg capsules and the number of eggs and embryos were remarkably increased with the increase of female shell heights (or ages) and also increased with the increase of salinity concentrations. Heights of egg capsules, the number of egg capsules and fecundities (the number of eggs and embryos) were the maximum at S-1 (Gwangyang Bay (average 31.5 psu)) and the minimum at S-3 (the upper reaches of Seomjin River (average 15.5 psu)). Total numbers of fecundities of R. venosa $individual^{-1}year^{-1}$ were about $1{\times}10^6$ at S-1 region, about $8{\times}10^5$ at S-2 region, and about $2{\times}10^5$ at S-3 region. Rates (50%) of individuals reaching first sexual maturities in three different salinity regions (S-1, S-2 and S-3) were over 50% in females measuring 7.1-8.0 cm in shell height (considered to be two years old), and 100% in those > 10.1 cm (considered to be five years old). Biological minimum sizes ($RM_{50}$) in females in three different regions are 72.0 mm SH at S-1 region, 70.9 mm SH at S-2 region, and 74.6 mm SH at S-3 region, respectively. Exceptionally, smaller individuals (considered to be one year old) were participated in reproduction.