• Journal of Korean Neurosurgical Society
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• 제50권4호
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• pp.381-384
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• 2011

The authors report a case of atypical extraventricular neurocytoma (EVN) transformed from EVN which had been initially diagnosed as an oligodendroglioma 15 years ago. An 8-year-old boy underwent a surgical resection for a right frontal mass which was initially diagnosed as oligodendroglioma. When the tumor recurred 15 years later, a secondary operation was performed, followed by salvage gamma knife treatment. The recurrent tumor was diagnosed as an atypical EVN. The initial specimen was reviewed and immunohistochemistry revealed a strong positivity for synaptophysin. The diagnosis of the initial tumor was revised as an EVN. The patient maintained a stable disease state for 15 years after the first operation, and was followed up for one year without any complications or disease progression after the second operation. We diagnosed an atypical extraventricular neurocytoma transformed from EVN which had been initially diagnosed as an oligodendroglioma 15 years earlier. We emphasize that EVN should be included in the differential diagnosis of oligodendroglioma.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제41권4호
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• pp.171-175
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• 2015

Objectives: The objective of this study was to identify salivary and serum concentrations of interleukin (IL)-8, IL-6, and tumor necrosis factor alpha ($TNF-{\alpha}$) in patients with oral lichen planus, oral leukoplakia, oral submucous fibrosis, and healthy controls. Materials and Methods: Patients selected included 54 oral lichen planus (41 to 65 years), 50 oral leukoplakia (42 to 65 years), 51 oral submucous fibrosis (41 to 65 years), and 50 healthy controls (42 to 65 years). Oral lichen planus, oral leukoplakia, and oral submucous fibrosis cases were diagnosed using histopathological analysis. Salivary and serum cytokine concentrations were measured using enzyme-linked immunoassay kits in all subjects. Results: The levels of serum and salivary $TNF-{\alpha}$, IL-6, and IL-8 were statistically significantly increased in oral leukoplakia, submucous fibrosis, and lichen planus in contrast to normal healthy subjects (P<0.05). Serum and salivary correlation analysis revealed strong and highly significant correlations for $TNF-{\alpha}$, IL-6, and IL-8 in all groups (r=0.72-0.82, P<0.05). Conclusion: Salivary and serum cytokines were also elevated when analyzed in oral precancerous lesions. Thus, salivary and serum IL-8, IL-6, and TNF-${\alpha}$ levels might act as diagnostic markers for detection of oral precancer.

• Infection and chemotherapy
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• 제50권4호
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• pp.301-310
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• 2018

Backgroud: Influenza vaccination is recommended for adults aged ${\geq}65$ years as they are at high risk of significant morbidity and mortality. This open-label, multicenter, post-marketing surveillance study assessed the safety of the MF59-adjuvanted trivalent inactivated subunit influenza vaccine, which is marketed as $FLUAD^{(R)}$ and $VANTAFLU^{(R)}$, in South Korean subjects aged ${\geq}65$ years. Materials and Methods: Solicited local and systemic adverse events (AEs) were collected from day 1 to 4 of the study. All unsolicited AEs and serious AEs (SAEs) were recorded from day 1 until study termination (day 29). Results: Of the 770 subjects enrolled ($FLUAD^{(R)}$, n = 389; $VANTAFLU^{(R)}$, n = 381), 39% overall experienced any solicited AE. Local AEs were reported by 33% of subjects overall; with the most common events being injection-site pain (30%) and tenderness (27%). Systemic AEs were reported by 19% of subjects overall with the most common events being myalgia (11%) and fatigue (8%). Conclusion: These results show that the MF59-adjuvanted influenza vaccine known as $FLUAD^{(R)}$ or $VANTAFLU^{(R)}$ had acceptable safety profiles in older adults (aged ${\geq}65$ years) in South Korea.

• International journal of advanced smart convergence
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• 제11권3호
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• pp.197-205
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• 2022

In order to investigate the effect of an 8-week elastic band exercise program according to age on the isokinetic strength and dynamic equilibrium of the knee, 10 women under 49 years old and 10 women over 50 years old were selected. Dynamic equilibrium was measured through Y-Balance test one week before the exercise program, and power and endurance were confirmed by measuring isokinetic muscle strength of the knee. After measurement, small tool exercise was performed for 8 weeks. After 8 weeks of exercise, isokinetic muscle strength and dynamic equilibrium were measured. As a result, isokinetic muscle strength, which checks muscle strength and muscular endurance, increased after measurement than before measurement regardless of age, and dynamic equilibrium increased after measurement rather than before measurement, and the group under 49 years of age was higher than the group over 50 years old. We think that small tool exercise improves isokinetic muscle strength and is effective in neuromuscular development, improving dynamic stability ability, which is an important factor in preventing falls.

• Nuclear Engineering and Technology
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• 제54권12호
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• pp.4499-4513
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• 2022

Spent fuel behavior of dry storage was simulated in a continuous state from steady-state operation by modifying FRAPCON-4.0 to incorporate spent fuel-specific fuel behavior models. Spent fuel behavior of a typical PWR was compared with that of NuScale Power Module (NPM^TM). Current PWR discharge burnup (60 MWd/kgU) gives a sufficient margin to the hoop stress limit of 90 MPa. Most hydrogen precipitation occurs in the first 50 years of dry storage, thereby no extra phenomenological safety factor is identified for extended dry storage up to 100 years. Regulation for spent fuel management can be significantly alleviated for LWR-based SMRs. Hydride embrittlement safety criterion is irrelevant to NuScale spent fuels; they have sufficiently lower plenum pressure and hydrogen contents compared to those of PWRs. Cladding creep out during dry storage reduces the subchannel area with burnup. The most deformed cladding outer diameter after 100 years of dry storage is found to be 9.64 mm for discharge burnup of 70 MWd/kgU. It may deteriorate heat transfer of dry storage by increasing flow resistance and decreasing the view factor of radiative heat transfer. Self-regulated by decreasing rod internal pressure with opening gap, cladding creep out closely reaches the saturated point after ~50 years of dry storage.

• 한국토양비료학회지
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• 제20권1호
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• pp.23-28
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• 1987

간척년수(干拓年數)에 따라 토층별(土層別) 토성(土性)이 다른 토양(土壤)에서 수종토양화학성분(數種土壤化學成分) 변화정도(變化程度)를 알고저 봉남통(鳳南統), 광활통(廣活統) 및 만경통(萬頃統)의 답토양(畓土壤)을 공시(供試)하여 시험(試驗)한 결과(結果)를 보면 다음과 같다. 1. 토양중(土壤中) 가리(加里), 석회(石灰), 고토(苦土), 소-다, 망간, 규산(硅酸) 및 양(陽)ion 치환용량등(置換容量等)은 간척년수(干拓年數)가 경과(經過)할수록 현저(顯著)한 감소(減少)를 보였음. 2. 토양유기물함량(土壤有機物含量)은 간척년수(干拓年數)의 경과(經過)에 따라 증가(增加) 되었는데 증가정도(增加程度)는 사질토양(砂質土壤)에서 현저(顯著)하였다. 그리고 우리나라 전국답토양(全國沓土壤) 평균치(平均値) 2.5%에 달(達)하기 위해서는 간척후(干拓後) 식질토양(埴質土壤)은 30년(年) 양질(壤質)과 사질토양(砂質土壤)은 약(約) 80년(年)이 경과(經過)되어야 할 것으로 예측(豫測)되어짐. 3. 토양중(土壤中) 가리활성도비(加里活性度比)는 토성(土性) 및 작토층위(作土層位)에 따라 상이(相異)했으나 일반답토양(一般沓土壤)의 평균(平均) 0.05~0.2 정도(程度)에 달(達)하기 위해서는 약(約) 50년(年)이 소요(消要)될 것으로 예측(豫測)되어짐. 4. $Na^{{+}{+}}$ion의 흡수율(吸收率), 흡착비등(吸着比等)은 간척년수(干拓年數)에 따라 현저(顯著)한 차이(差異)를 보였는데 특(特)히 사질토양(砂質土壤)에서 감소(減少)의 정도(程度)가 뚜렷하였음. 5. 간척년수(干拓年數)에 따른 점토함량변화(粘土含量變化)는 토층별(土層別)로 상이(相異)했는데 간척후(干拓後) 30년경(年頃)까지는 심토(深土)의 용탈(溶脫)이 현저(顯著)했으나 50년(年) 이후(以後)는 표토(表土)에서 용탈(溶脫)이 큰 경향(傾向)을 보였음.

• 한국산학기술학회논문지
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• 제11권12호
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• pp.4896-4906
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• 2010

2010년 D대학 치위생과 3학년 200명을 대상으로 해외 진학 및 취업에 관심이 있는 아시아 국가를 조사한 결과, 일본이 114명(60.3%)으로 가장 높게 나왔고, '기회가 된다면 아시아권 해외 진학 및 취업을 희망하십니까?'라는 질문에 그렇다가 72명(38.1%)으로 가장 많았다. 가장 관심이 높았던 일본은 2년제 51개 대학, 3년제 101개 대학, 4년제 6개 대학으로 총 158개 대학에서 치위생학과가 개설되어 있었고, 학교 법인은 관동지방(간토)이 25개로 가장 많았다. 일개 학제별 한 일 교육과정을 분석한 결과, 동일하거나 유사한 교과목이 다수였으며, 3년제는 39개 4년제는 44개였다. 일본의 국가고시 교과목이 19개 과목으로 해부학 외 9개 과목이 100점, 치과임상개요의 치과임상개론 외 8개 과목이 50점, 치과진료보조 외 1과목이 50점으로 총 배점이 200점이였고, 일본의 4년제 치위생사양성과정은 졸업 후 치과위생사 면허와 함께 동경의과치과대학 치과구강보건학과에서 사회복지사, 히로시마대학 치과 구강건강과학과는 양호교사(보건교사) 1종 면허 등을 선택적으로 동시에 자격을 취득할 수 있도록 업무영역을 확대한 교육과정을 편성하고 있다.

• 대한간호학회지
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• 제7권1호
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• pp.30-38
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• 1977

Breast cancer is one of the most feared health problems in women ; Recent studies revealed that it had come up to be the second most in this country and high prevalent disease in the western countries among breast disease in women. However, early detection of the cancer mass is known to be easier than in many other malignancies. This study was performed to investigate the various characteristics of patients of breast cancer ; by the structural variables, menstrual, marital, and child bearing, and also their understandings and attitude towards the disease. A hundred any in- and out- patients of 51. Mary's Hospital and National Atomic Institute, Seoul were sampled. Data were gathered through direct interview by the researcher from February 1976 to January 1977 and the clinical records were used as references. Results are as follows ; 1. Breast cancer revealed to be most prevalent in the forties ; average age of 45.2 years. 2. The average age of menarche revealed to be 15.4 years ; the largest group were the 16-20 years (N=75, 68.2%). In 55 cases (50%) menstruation were normal, 38 (34.5%) postmenopausal and only in 17 (15.5%), menstruation revealed irregularity. 3. The average marital age revealed to be 22.3 years ; the largest group were 21-25 group (N=43, 39.1%). The average duration of marital life revealed to be 24.7 years ; 11-20 years group were the largest (M=34, 30.9%). 4. Most of the patients revealed to have pregnancy experiences(N=100, 90.9%) ; the average rate of experience were 5, 3 times the largest group were 3.4 times group(N= 32, 29.1%). 54 patients (49.1%) revealed to have had abortion experience ; the average were 3.4 times. 5. The largest group(N=77, 70%) had been breast feeding : followed by mixed feeding (N=12, 10.9%) and artificial feeding(N=10, 9.1%). 6. Personal health history revealed that in 20 patients (18.2%) revealed to have the past history of Purulent mastitis, 5 patients(4.5%) of breast cancer and 3 patients(2.7%) of uttering cancer family history. 7. In the one half (N=56, 50.9%, they had some information about breast cancer :27 (24.5%) by mass media, 12 (10.9%) through personal contacts and 17 (15.5%) were not able to classify the source of information. 8. In 55 cases (50%) the canoe, mass were discovered incidentally, in 39 cases (35.5%) by manual detection by self, in 10 cases (9%) by others and in 6 cases(5.5%) by observing subjective symptoms. 9. The average duration lapsed between the discovery of cancer mass and the visit to the hospital revealed to be 9.4 month. Chief reason for the delay revealed to be the non-chaplaincy due to the absence of pain(N=50, 45.5 %) followed by the administration of herb and commercial medication (N=19, 17.3%). 10. The left side breast was more affected than the right side breast, represent by 60 cases in the left and 39 cases in the right. The most frequent site of the breast cancer was the upper- outer quadrant in 53 cases (47.7%), and followed by the center in 20 cases(18 %), and the upper inner quadrant, in 19 cases (17.1%). There was / cases of bilateral carcinoma. The most prominent symptom was painless mass.

• Korean Journal of Health Education and Promotion
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• 제1권1호
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• pp.95-117
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• 1999

As the nation is moving into the 21st century, the fundamental challenge facing local health departments in the United States is to improve the quality of peoples lives by preventing disease, injury, and disability through collaboration with public and private partners. During this century, life expectancy in the United States has increased remarkably from less than 50 years at the turn of the century to 79 years for woman and 72 years for men (CDC 1999; Bunker et al. 1994). Major portions of this gain can be attributed to advances in public health. (omitted)

• 대한임상검사과학회지
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• 제46권1호
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• pp.17-21
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• 2014

The prevalence of hepatitis A virus (HAV) in a certain community reflects that community's living standard and hygienic condition. The seroprevalence rate of IgG anti-HAV has been changing with regions and times. In this study, we aimed to study the difference of seroprevalence of IgG anti-HAV according to sex, age and type of drinking water, and to know the vaccination rate and seroconversion rate for vaccinated subjects in Busan. A total of 644 samples were analyzed. The overall seroprevalence rate of IgG anti-HAV was 35.4% (228/644). There was no significant difference in sex (male 39.8%, female 32.7) (p>0.05). According to age, seroprevalence rate of anti-HAV were 55.0% in subjects aged 5~9 years old, 47.8% in 10~14 years old, decreced to 10.6% in 15~19 years old, 1.0% in 20~24 years old, 0.0% in 25~29 years old and increced with advacing ages ; 14.7% in 30~34 years old, 39.4% in 35~39 years old, 67.3% in 40~44 years old, 94.1% in 45~49 years old, 100.0% over 50 years (p<0.001). The seroprevalence of IgG anti-HAV was no statistical difference according to the types of drinking water (p>0.05). The vaccinated subject was 42 case only in below 25 years old. The seroconversion rate after vaccination was 88.1%.