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Regurgitation and Gastroesophageal Reflux Disease in Six to Nine Months Old Indonesian Infants

  • Hegar, Badriul;Satari, Debora Hindra I.;Sjarif, Damayanti R.;Vandenplas, Yvan
    • Pediatric Gastroenterology, Hepatology & Nutrition
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    • v.16 no.4
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    • pp.240-247
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    • 2013
  • Purpose: Regurgitation is known to peak at the age of 3-4 months, with a sharp decrease around the age of 6 months. Little is known about the natural evolution of infants who still regurgitate after the age of 6 months. Methods: Hundred thirty-one infants older than 6 months regurgitating more than once a day were followed for a period of 3 months. Results: According to our data, gastroesophageal reflux disease (GERD) is seldom at this age. Most of the infants regurgitated 3 or more times/day and spit up an estimated volume of more than 15 mL. Eighty-five parents were educated regarding frequency of feeding. There were only 6 infants that still had frequent regurgitation (>3 times/day) despite an appropriate feeding schedule. The Infant GER Questionnaire score reached a score of 0 in 50% of the infants after one month of follow-up and in 81.9% at the third month of follow-up. There was an increase of the "weight for age z-score" trends in infants that still regurgitated at the end of follow-up and a declining z-score in infants that no longer regurgitated. An explanation may be that infants that regurgitate drink larger volumes than infants who do not regurgitate. Conservative treatment (reassurance, dietary treatment, behavioral advice) resulted in a significant better outcome than natural evolution. Conclusion: Regurgitation that persisted after the age of 6 months, strongly decreased during a 3-month follow-up with conservative treatment. GERD is rare in this age group; therefore, anti-reflux medication is only seldom needed.

Design Principles and Validation of a Human-sized Quadruped Robot Leg for High Energy Efficiency (에너지 효율적인 인간 크기 4족 보행 로봇의 설계와 검증)

  • Yeom, Hoyeon;Ba, Dang Xuan;Bae, Joonbum
    • The Journal of Korea Robotics Society
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    • v.13 no.2
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    • pp.86-91
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    • 2018
  • This paper presents about design efforts of a human-sized quadruped robot leg for high energy efficiency, and verifications. One of the representative index of the energy efficiency is the Cost of Transport (COT), but increased in the energy or work done is not calculated in COT. In this reason, the input to the output energy efficiency should be also considered as a very important term. By designing the robot with customized motor housing, small rotational inertia, and low gear ratio to reduce friction, high energy efficiency was achieved. Squatting motion of one leg was performed and simulation results were compared to the experimental results for validation. The developed 50 kg robot can lift the weight up to 200 kg, and during squatting, it showed high energy efficiency. The robot showed 71% input to output energy efficiency in positive work. Peak current during squatting only appears to be 0.3 A.

Nonlinear spectral design analysis of a structure for hybrid self-centring device enabled structures

  • Golzar, Farzin G.;Rodgers, Geoffrey W.;Chase, J. Geoffrey
    • Structural Engineering and Mechanics
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    • v.61 no.6
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    • pp.701-709
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    • 2017
  • Seismic dissipation devices can play a crucial role in mitigating earthquake damages, loss of life and post-event repair and downtime costs. This research investigates the use of ring springs with high-force-to-volume (HF2V) dissipaters to create damage-free, recentring connections and structures. HF2V devices are passive rate-dependent extrusion-based devices with high energy absorption characteristics. Ring springs are passive energy dissipation devices with high self-centring capability to reduce the residual displacements. Dynamic behaviour of a system with nonlinear structural stiffness and supplemental hybrid damping via HF2V devices and ring spring dampers is used to investigate the design space and potential. HF2V devices are modelled with design forces equal to 5% and 10% of seismic weight and ring springs are modelled with loading stiffness values of 20% and 40% of initial structural stiffness and respective unloading stiffness of 7% and 14% of structural stiffness (equivalent to 35% of their loading stiffness). Using a suite of 20 design level earthquake ground motions, nonlinear response spectra for 8 different configurations are generated. Results show up to 50% reduction in peak displacements and greater than 80% reduction in residual displacements of augmented structure compared to the baseline structure. These gains come at a cost of a significant rise in the base shear values up to 200% mainly as a result of the force contributed by the supplemental devices.

Effect of nitrogen concentration on the microstructures of AlN thin films fabricated by reactive RF sputtering (반응성 RF 마그네트론 스퍼터링으로 증착한 AlN 박막의 특성에 질소농도 변화가 미치는 영향)

  • Lim, Dong-Ki;Kim, Byoung-Kyun;Jeong, S.W.;Roh, Yong-Han
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2008.06a
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    • pp.367-367
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    • 2008
  • Aluminum nitride (AlN) thin films have been deposited on Si substrate by using reactive RF magnetron sputtering method in a gas mixture of Ar and $N_2$ at different $N_2$ concentration. It was found that $N_2$ concentration was varied in the range up to 20-100%, highly c-axis oriented film can be obtained at 50% $N_2$ with full width at half maximum (FWHM) $4.5^{\circ}$. Decrease in surface roughness from 7.5 nm to 4.6 nm found to be associated with decrease in grain size, with $N_2$ concentration; however, the AlN film fabricated at 20% $N_2$ exhibited a granular type of structure with non-uniform grains. The absorption peak was observed around 675 $cm^{-1}$ in fourier transform infrared spectroscopy (FTIR). It is concluded that the AlN film deposited at $N_2$ concentration of 50% exhibited the most desirable properties for the application of high-frequency surface acoustic devices.

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$^{13}C$ Solid State NMR Study on the Dynamics of the Poly(vinyl butylal) with Various Water Contents

  • Hyun Namgoong;Kim, Jong-Soo;Han, Oc-Hee
    • Journal of the Korean Magnetic Resonance Society
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    • v.6 no.1
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    • pp.1-11
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    • 2002
  • Physical properties of PVB [Poly(vinyl butyral)] polymer are strongly correlated with water contents in the polymer. Thus dynamics of PVB containing 10~50(w/w) % of water were studied by $^{13}$ C CP/MAS/DD over the temperature range 293K -348K. From the Peak area, line width, chemical shift, and relaxation times ( $T_{1}$ $T_{1p}$) measured at 9.4 T, it was deduced that water facilitates molecular dynamics of the PVB molecules overall including conformational exchange of the racemic and meso butyaldehyde rings in the PVB. However, the influence of water was not linear to the amount of water in the PVB samples. It is suggested that water up to 30 w/w % of the sample is closely bound to the PVB polymer and water relatively free from the PVB polymer starts to appear when water is added more than 30 w/w %.%.

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The Production and Enzymatic Properties of Extracellular Chitinase from Pseudomonas stutzeri YPL-1, as a Biocontrol Agent

  • Lim, Ho-Seong;Kim, Sang-Dal
    • Journal of Microbiology and Biotechnology
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    • v.4 no.2
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    • pp.134-140
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    • 1994
  • An antagonistic bacterium Pseudomonas stutzeri YPL-1 liberated extracellular chitinase and $\beta$-1,3-glucanase which are key enzymes in the decomposition of fungal hyphal walls. The lytic enzymes caused abnormal swelling and retreating at the hyphal tips of plant pathogenic fungus Fusarium solani in a dual culture. Scanning electron microscopy revealed the hyphal degradation of F. solani in the regions interacting with P. stutzeri YPL-1. The production of chitinase and properties of a crude preparation of the enzyme from P. stutzeri YPL-1 were investigated. Peak of the chitinase activity was detected after 4 hr of cultivation. The enzyme had optimum temperature and pH of 50$^{\circ}C$ and pH 5.3, respectively. The enzyme was stable in the pH range of 3.5 to 6.0 up to 50$^{\circ}C$. The enzyme was significantly inhibited by metal compounds such as $HgCl_2$, but was stimulated by $CoCl_2$. P. stutzeri YPL-1 produced high levels of the enzyme after 84 hr of incubation. Among the tested carbon sources, chitin was the most effective for the enzyme production, at the concentration level of 3%. As a source of nitrogen, peptone was the best for the enzyme production, at the concentration level of 4%. The maximum amount of enzyme was produced by cultivating the bacterium at a medium of initial pH 6.8.

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Acid-Sensitivity and Physical Properties of Polymethylmethacrylate and Polyurethane Films Containing Polymeric Styryl Dye

  • Cho, Jae-Whan;Lee, Sun-Hwa;So, Jung-Hyun;Jaung, Jae-Yun;Yoon, Kee-Jong
    • Fibers and Polymers
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    • v.5 no.3
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    • pp.239-244
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    • 2004
  • Solution-cast films of polymethylmethacrylate (PMMA) and polyurethane (PU) containing polymeric styryl dye up to 5 % by weight were prepared to investigate their acid-sensitivity and mechanical and thermal properties. Original red samples due to styryl dye turned out yellow very rapidly as they were exposed to acid vapor of hydrochloric acid or p-toluenesulfonic acid. According to UV/VIS spectroscopic measurements, characteristic peak intensities near 430 nm and 520 nm increased or decreased relatively with exposed amounts of acid, respectively. Both PMMA and PU samples showed uniform color distribution due to a good miscibility between polymer and dye which can be evidenced by measurements of glass transition temperature. No significant difference in acid-sensitivity was found between PU and PMMA except relative absorbance. However, dependence of their mechanical properties on dye content was somewhat different with PU or PMMA. In case of PMMA, modulus and breaking stress increased up to about 50 % with increasing dye content, whereas those of PU samples showed only slight increase. It was ascribed to whether the matrix polymer was in the glassy or rubbery state.

Follow up study of pulmonary function after pneumonectomy (일측 폐절제술후 폐기능의 추적관)

  • Park, Jae-Gil;Kim, Se-Hwa;Lee, Hong-Gyun
    • Journal of Chest Surgery
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    • v.16 no.4
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    • pp.539-546
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    • 1983
  • Maximal expiratory flow-volume [MEFV] curves were studied in 22 patients who underwent pneumonectomy with various pulmonary lesions, such as lung cancer, bronchiectasis and tuberculosis etc, at the preoperative stage and 3 week, 4 month and 12 month after pneumonectomy for the analysis of the reduction and progressive improvement of postoperative ventilatory function. And the factors affecting them like as age difference and the site of pneumonectomy were also analyzed. From these curves peak flow rate [PF R], maximal expiratory flows at 25% and 50% of expired forced vital capacity [V25, V50] and forced vital capacity [FVC] were obtained. In addition, partial pressure of oxygen and carbon dioxide in arterial blood were measured. The results were as follows; 1. The mixed type, especially obstructive type of ventilatory impairment was observed at 3 week after operation. For 1 year of postpneumonectomy FVC was increased by 12.3% of predicted compared to 2.6% of predicted V50. 2. The improvement of FVC during 1 year of postpneumonectomy showed decreasing tendency with the increase of age but the changes of V25 and V50 were unremarkable. 3. The differences of immediate postoperative reduction and progressive improvement of ventilatory capacity after right and left pneumonectomy were analyzed. The reduction of V50, V25 and FVC at 3 week of postoperation were greater in patients with right pneumonectomy [20.9%, 18.2% and 26.2% of predicted] than in patients with left pneumonectomy 16.5%, 18.2% and 18.1%]. But there was no significant difference of these values at 12 month after pneumonectomy. 4. The partial pressure of oxygen in arterial blood [$PaO_2$] was decreased by 13.6 mmHg at 3 week after pneumonectomy compared to the preoperative stage but returned to the normal range within 4 month after pneumonectomy. However, TEX>$PaCO_2$ was within the normal range during 1 year of postoperation.

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Combined X-ray CT/SPECT System with a Common CZT Detector (CZT검출기를 이용한 CT/SPECT 조합영상시스템)

  • 권수일
    • Progress in Medical Physics
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    • v.13 no.4
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    • pp.229-233
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    • 2002
  • We have tested a combined CT/SPECT system with a single CZT detector for x-ray and gamma-ray medical imaging. The size of detector is 10$\times$10$\times$5 ㎣, and the anodes are pixellated as a 4$\times$4 array with a pixel dimension of $1.5\times$1.5 $\textrm{mm}^2$. The cathode was coated with a continuous Au-plated. We have characterized the system performance by scanning a radiographic resolution phantom and the Hoffman Brain phantom. Pulse counting electronics with very short shaping time (50 ㎱) are used to satisfy high photon rates in x-ray imaging, and response linearity up to 3$\times$10$^{5}$ counts per second per detector element is achieved. Energy resolution of 10.4% and 5.3% FWHM at Tc-99m 140 keV peak are obtained for the 50 ㎱ and 2 $mutextrm{s}$ shaping times, respectively. The spatial resolutions of CT and SPECT are about 1mm and 9mm, respectively. Photopeak efficiency of detector systems are 41.0% for 50㎱ and 72.5% for 2 $mutextrm{s}$ shaping time.

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The Waveform and Spectrum analysis of Tursiops truncatus (Bottlenose Dolphin) Sonar Signals on the Show at the Aquarium (쇼 학습시 병코돌고래 명음의 주파수 스펙트럼 분석)

  • 윤분도;신형일;이장욱;황두진;박태건
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.36 no.2
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    • pp.117-125
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    • 2000
  • The waveform and spectrum analysis of Tursiops truncatus(bottlenose dolphin) sonar signals were carried out on the basis of data collected during the dolphin show at the aquarium of Cheju Pacificland from October 1998 to February 1999. When greeting to audience, the pulse width, peak frequency and spectrum level from the five dolphins'sonar signals were 3.0ms, 4.54kHz and 125.6dB, respectively. At the time of warm-up just before the show, their figures were 5.0㎳, 5.24kHz and 127.0dB, respectively. During the performance of dolphins, with singing, peak frequency ranged 3.28∼5.78kHz and spectrum level ranged 137.0∼142.0dB. With playing ring, pulse width, peak frequency and spectrum level were 7.0㎳, 2.54kHz and 135.9dB, and when playing the ball, the values were 9.0㎳, 2.78kHz and 135.2dB, respectively. The values determined from the five dolphins during jump-up out of water were : pulse width 2.0㎳, peak frequency 4.50kHz and spectrum level 126.8dB. When they responded to trainer's instructions, the values were 2.25㎳, 248kHz and 148.7dB, respectively, and greeting to audience, the peak frequency and spectrum level were 5.84kHz and 122.5dB. During swimming under water, peak frequency and spectrum level were determined to be 10.10kHz and 126.8dB. It was found that there exited close consistencies in pulse width, frequency distribution and spectrum level between whistle sounds and dolphin's sonar signals. Accordingly, the dolphins can be easily trained by using whistle sound based on the results obtained from the waveform and spectrum of the dolphin's sonar signals.

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