• Title/Summary/Keyword: 5-Mers

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A Study of Factors Affecting Intention to Use Mobility Sharing Service (공유 모빌리티 서비스의 이용의도에 영향을 미치는 요인에 관한 연구)

  • Kim, Yong Seok;Pi, Chae Hee;Choi, Jeongil
    • Journal of Information Technology Services
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    • v.20 no.5
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    • pp.73-87
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    • 2021
  • The COVID-19 pandemic has brought about many changes in our daily lives and in industries as a whole. The most notable change was the spread of the untact culture to minimize face-to-face contact. The spread of the untact culture has changed the use of public transportation. Looking at the results of previous SARS and MERS studies, it was found that as the pandemic spreads, the use of public transportation decreased. Recently, the mobility sharing service is attracting attention as a personalized means of transportation instead of public transportation. Therefore, in this study, the factors affecting the intention to use the mobility sharing service were to be identified by the actual users. In this study, economic benefit, convenience, sustainability, and sense of belonging were set as independent variables based on previous studies. In addition, the relationship between the perceived usefulness and perceived pleasure of these factors of use on intention to use was empirically analyzed through PLS-SEM. As a result of the study, it was found that economic benefits, convenience, sustainability, and sense of belongingness had a significant effect on intention to use through perceived usefulness and enjoyment. This study was meaningful in that it was verified through the study that economic benefits, convenience, sustainability, and a sense of belongingness were significant variables affecting the intention to use through usefulness and pleasure.

Quantum Chemical Calculations on the Conformational Structure of the Alanine Oligomer Model (알라닌 올리고머의 배좌구조에 관한 양자화학적 계산)

  • Sim, Jae-Ho
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.2
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    • pp.1563-1570
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    • 2015
  • Conformational change during chain propagation of alanine oligomer was investigated by quantum chemical calculation(QCC) using 2~5mers(${\times}=2{\sim}5$) models. For estimation of the end group effects, two types of end group. "amide type" ($CH_3CONH-and-CONHCH_3$) and "methyl type" ($CH_3CONH-and-CONHCH_3$), were prepared as both ends(N-and-C). Conformers optimized for 5-mer converged to three types of ${\Phi}/{\Psi}$ : ${\alpha}$-helix(g+/g+, or g-/g-), PPII-like(extended helix-like, g+/g-, or g-/g+), and ${\beta}$-extended (t+/t-, or t-/t+), in the order of lower energy, and the energies of left- and right- handed conformers were the same (5-mer. amide type ${\Delta}E=-1.05$, right type ${\Delta}E=-1.62$). Energies of the monomer unit(${\Delta}E$) of ${\alpha}$-helix decreased with increases of monomer.

Stepwise Addition Technology for the High Yield Production of Chitosanoligosaccharide (키토산올리고당 생산을 위한 다단계 첨가방법)

  • Lee, Ki-Sun;Kim, Seung-Mo;Lim, Hyun-Soo
    • KSBB Journal
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    • v.14 no.6
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    • pp.639-642
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    • 1999
  • Optimization of the chitosanoligosaccharide production was studied with chitosanase. The optimum conditions for the enzymic reaction have been determined. Enzyme stability was maintained above 90% after 6 days at pH 5.0. The optimum initial reaction rate was appeared in 1.0% of chitosan solution. The production yield of chitosanoligosaccharides was over at 0.4%~2.0% of chitosan. At 4.0% of chitosan solution, however, the production yield was decreased to 64.6%. To increase the yield, stepwise addition of substrate into the reactor was investigated. In this case, the yield was increased from 64.6% to 83.2% and the final concentrations of chitosanoligosaccharide was 12.26 mg/mL. By TLC analysis, most of the chitosanoligosaccharides produced were 3-5 mers.

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Synthesis and Characterization of Polymers with the Moiety of 2-Phenylphenol as a Microbicide (항균제로서 2-페닐페놀의 Moiety를 가지는 고분자의 합성과 특성)

  • 현석희;김민우;전일련;김우식
    • Polymer(Korea)
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    • v.27 no.5
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    • pp.443-448
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    • 2003
  • 2-Biphenylyl acrylate (BPA) was synthesized by the reaction of 2-phenylphenol as a microbicide with acryloyl chloride, and copolymers with the moiety of 2-phenylphenol were prepared by the radical terpolymerization of BPA-methylmethacrylate-acrylic acid. The contents of BPA unit in the poly mers were found to be 4.2 mol% and 9.1 mol% from their nuclear magnetic resonance spectra. The number average molecular weights of the polymers were in the range of 15000 to 16000. 2-Phenylphenol was released through the hydrolysis of the polymers. The release rate of the microbicide increased with increasing pH of the release medium. The released solution showed higher microbicidal activity for E. coli as a negative microbe than S. aureus as a positive microbe.

A Study on the Guideline of Spatial Composition and Circulation in Triages and Entrances Area in Emergency Departments for Efficient Infection Control (응급부 진입구역과 환자분류구역의 감염관리를 위한 환자동선과 공간구성 계획에 대한 연구)

  • Kang, Jeeeun;Kwon, Soonjung
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.25 no.1
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    • pp.41-49
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    • 2019
  • Purpose: After Mers breakout in 2015, major hospital in Korea have been renovated the emergency department to make a separate infection control zone for high-risk patient with potential infection and to improve a triage area and an entrance area for efficient patient evaluation. However, there are no specific design standards to reinforce infection control for patients and staffs safety. Therefore, it is important to establish of initial design factors in the triage and entrance area as a guideline. Methods: 5 cases which had been recently renovated are selected to analyze patient circulation and spatial composition in a triage area and an entrance area. The partial floor plans of each case are represented as bubble diagrams to help understanding of different patient circulation flows. Based on this analysis, significant design factors which should be considered in planning stage for infection control have been extracted. Results: 13 design factors are established. Using these design factors, patient circulation diagram is generated to provide an optimized suggestion for efficient infection control. Implications: This suggestion provides basic databases to start to establish design guideline in the triage area and the entrance area to minimize infection spreading in the emergency department.

Identification and Expression of Equine MER-Derived miRNAs

  • Gim, Jeong-An;Kim, Heui-Soo
    • Molecules and Cells
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    • v.40 no.4
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    • pp.262-270
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    • 2017
  • MicroRNAs (miRNAs) are single-stranded, small RNAs (21-23 nucleotides) that function in gene silencing and translational inhibition via the RNA interference mechanism. Most miRNAs originate from host genomic regions, such as intergenic regions, introns, exons, and transposable elements (TEs). Here, we focused on the palindromic structure of medium reiteration frequencies (MERs), which are similar to precursor miRNAs. Five MER consensus sequences (MER5A1, MER53, MER81, MER91C, and MER117) were matched with paralogous transcripts predicted to be precursor miRNAs in the horse genome (equCab2) and located in either intergenic regions or introns. The MER5A1, MER53, and MER91C sequences obtained from RepeatMasker were matched with the eca-miR-544b, eca-miR-1302, and eca-miR-652 precursor sequences derived from Ensembl transcript database, respectively. Each precursor form was anticipated to yield two mature forms, and we confirmed miRNA expression in six different tissues (cerebrum, cerebellum, lung, spleen, adrenal gland, and duodenum) of one thoroughbred horse. MER5A1-derived miRNAs generally showed significantly higher expression in the lung than in other tissues. MER91C-derived miRNA-5p also showed significantly higher expression in the duodenum than in other tissues (cerebellum, lung, spleen, and adrenal gland). The MER117-overlapped expressed sequence tag generated polycistronic miRNAs, which showed higher expression in the duodenum than other tissues. These data indicate that horse MER transposons encode miRNAs that are expressed in several tissues and are thought to have biological functions.

The Effect of Hand Washing Procedure Poster on the Hand Washing Behaviors (성인의 손씻기 실태 및 손씻기 포스터의 효과)

  • Chaung, Seung Kyo
    • The Journal of the Convergence on Culture Technology
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    • v.4 no.3
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    • pp.269-274
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    • 2018
  • This study was done to identify the effects of the hand washing procedure poster on the hand washing behaviors after Mers outbreak. Method: This study was conducted by observing a total of 370 people(185 people in no- poster zone, 185 people in poster zone) who used the public restroom. Results: As a result of comparing the hand washing with and without the poster, the subjects who washed their hands with the poster around were 83.2%, which was higher than the 47% of the subjects without the poster. The Time spent on the hand washing was similar between the groups with or without the poster around. Also only 3.3% of the subjects actually completed the entire 6 procedures of hand washing. The subjects who finished more than 4 procedures out of 6 were 17% from the group with the poster around, and 10.3% from the group without. Conclusion: The hand washing poster was effective in encouraging the behavior itself, but not specifically in the right way during the ideal time nor the right procedures. Therefore, verbal instructions made every time washing hands or more visual effective posters are required to enhance the hand washing procedures.

Characterization of simple sequence repeats in the Pleurotus ostreatus cultivars, 'Heuktari' and 'Miso' (느타리버섯 품종 '흑타리'와 '미소'의 초위성체 특성구명)

  • Park, Bokyung;Ha, Byeong Seok;Kim, Min Keun;Lee, Byungjoo;Choi, Jong In;Ryu, Jae-San
    • Journal of Mushroom
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    • v.14 no.4
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    • pp.174-178
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    • 2016
  • Simple sequence repeats (SSR), also referred to "microsatellites" consist of tandemly repeated short DNA sequence motifs and have been applied in various marker-based studies. SSRs were isolated and characterized from 'Heuktari' and 'Miso', which are major oyster mushroom cultivars in Korea, by genome sequencing and bioinformatic analysis. The genome sizes of 'Heuktari' and 'Miso' were estimated to be 40.8 and 40.3 Mb, respectively, which are larger than those of other P. ostreatus species (PC9 and PC10) and smaller than those of P. eryngii (KNR2312P5). In total, 949 and 968 SSRs were found in the 'Heuktari' and 'Miso' genomes, respectively. Comparative analysis of five mushrooms including P. ostreatus var. florida (PC9 and PC15) and P. eryngii revealed that the number of SSRs in 'Heuktari' and 'Miso' were the highest among them. All mushrooms studied showed similar SSR distribution patterns. Tri-, hexa-, and octanucleotide motifs accounted for the top three fractions of all SSRs.

A Feasibility Study of Hand Hygiene Status in Korea Hospitals (국내병원의 유형별 손위생 수행실태 조사분석)

  • Lee, Yongkyoon;Shin, Hyunhee
    • Journal of The Korea Institute of Healthcare Architecture
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    • v.23 no.3
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    • pp.9-17
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    • 2017
  • Purpose : The easiest and most cost-effective way to prevent medical-related infections is known as proper hand washing of health care workers. The experience of MERS in domestic medical institutions has increased the importance of hand hygiene for medical workers to prevent infections in hospitals. It is necessary to investigate the level of hand hygiene practice by type of medical institutions and the factors influencing the infection prevention. Methods : Domestic and overseas hand hygiene related business cases and literature data were collected and analyzed in order to investigate the hand hygiene status of medical institutions in Korea. Result : As a result of hand hygiene monitoring of all hospital-level medical institutions in 2016, the total number of observations was 24,328 and the hand hygiene performance rate was 75.9%. The hand hygiene performance rate of hospitals was 71.5% for general hospitals, 75% for general hospitals, and 81.3% for hospitals. Implications : In general hospitals and hospitals, the HR(Hand Rubbing) method is preferred as a way of performing hand hygiene, whereas the HW(Hand Washing) method is relatively high in the small hospitals. It is estimated that the HW system is preferred because of the cost burden at the hospital medical institution. Therefore, it is necessary to compensate the related expenses to improve the hand hygiene performance of the physicians who are engaged in the hospitals.

The Impact of Pandemic Crises on the Synchronization of the World Capital Markets (팬데믹 위기가 세계 자본시장 동조화에 미치는 영향)

  • Lee, Dong Soo;Won, Chaehwan
    • Asia-Pacific Journal of Business
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    • v.13 no.3
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    • pp.183-208
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    • 2022
  • Purpose - The main purpose of this study is to widely investigate the impact of recent pandemic crises on the synchronization of the world capital markets through 25 stock indices from major developed countries. Design/methodology/approach - This study collects 25 stock indices from major developed countries and the time period is between January 5, 2001 and February 24, 2022. The data sets used in the study include finance.yahoo.com and Investing.com.. The Granger causality analysis, unit-root test, VAR analysis, and forecasting error variance decomposition were hired in order to analyze the data. Findings - First, there are significant inter-relations among 25 countries around recent major pandemic crises(such as SARS, A(H1N1), MERS, and COVID19), which is consistent result with previous literature. Second, COVID19 shows much stronger impact on the world-wide synchronization than other pandemics. Third, the return volatility of each stock market varies, unit root tests show that daily stock index data are unstable while daily stock index returns are stable, and VAR(Vector Auto Regression) analyses presents significant inter-relations among 25 capital markets. Fourth, from the impulse response function analyses, we find that each market affects the other markets for short term periods, about 2~4 days, and no long term effect was not found. Fifth, Granger causality tests show one-side or two-sides synchronization between capital markets and we estimate, through forecasting error variance decomposition method, that the explanatory portions of each capital market on other markets vary from 10 to 80%. Research implications or Originality - The above results all together show that pandemic crises have strong effects on the synchronization of world capital markets and imply that these synchronizations should be carefully considered both in the investment decisions by individual investors and in the financial and economic policies by governments.