• Journal of the Korean Chemical Society
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• v.34 no.5
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• pp.476-482
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• 1990

The relationship between chemical structure and antifungal activity of benzene ring substituents of 3-phenyl-5,5-dimethyloxazolidine-2,4-diones is studied by testing of model compounds and use of conformational data. The analysis revealed a number of structural features as essential for the antifungal effect: (1) the presence of an intact -NCO group and benzene moiety; (2) the distance between para substituents and the N atom within the 5.32∼5.37${\AA}$ range; (3) the distance between substituents X3 and X4, in the interval 5.59 ∼ 5.77 ${\AA}$ for the active analogues.

• Archives of Pharmacal Research
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• v.24 no.5
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• pp.390-396
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• 2001

Synthesized 6-arylamino-5,8-quinolinediones 4a-4j and 6-chloro-7-arylamino-5,8-isoquinolinediones 5a-5g were evaluated for effects on NAD(P)H quinone oxidoreductase (NQOl ) activity with the cytosolic fractions derived from cultured human lung cancer cells and their cytotoxicity in cultured several human solid cancer cell lines. The 5,8-quinolinediones 4 and 5,8-isoquinolinediones 5 affected the reduction potential by NQO1 activity and showed a potent cytotoxic activity against human cancer cell lines. The tested compounds 4a, 5c, 5f, and 5g were considered as more potent cytotoxic agents. The compounds 4d, 5b, 5c, 5e and 5g were comparable modulators of NQO1 activity.

• Korean Journal of Fisheries and Aquatic Sciences
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• v.30 no.1
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• pp.46-54
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• 1997

Sporulation in the fission yeast Schizosaccharomyces pombe has been regarded as an important model of cellular development and differentiation. S. pombe cells proliferate by mitosis and binary fission on growth medium. Deprivation of nutrients especially nitrogen sources, causes the cessation of mitosis and initiates sexual reproduction by malting between two sexually compatible cell types. Meiosis is then followed in a diploid cell in the absence of nitrogen source. DNA fragment complemented with the mutations of sporulation gene was isolated from the S. pombe gene library constructed in the vector, pDB 248' and designated as pDB (spo 5)1. We futher analyzed six recombinant plasmids, pDB (spo 5)2, pDB(spo 5)3, pDB(spo 5)4, pDB(spo 5)5, pDB(spo 5)6, pDB(spo 5)7, and found each plasmids is able to rescue the spo 5-2, spo 5-3, spo 5-4, spo 5-5, spo 5-6, spo 5-7, mutations, respectively. Mapping of the integrated plasmid into the homologous site of the S. pombe chromosomes demonstrated that pDB (spo 5)1, and pDB (spo 5)R1 contained the spo 5 gene. Transcipts of spo 5 gene were analyzed by Northern hybridization. Two transcripts of 3.2 kb and 25 kb were detected with 5 kb Hind III fragment containing a part of the spo 5 gene as a probe. The small mRNA (2.5 kb) appeared only when a wild-type strain was cultured in the absence of nitrogen source in which condition the large mRNA (3.2 kb) was produced constitutively. Appearance of a 2.5 kb spo 5-mRNA depends upon the function of the mei1, mei2 and mei3 genes.

• Journal of the Korean Vacuum Society
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• v.19 no.2
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• pp.134-140
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• 2010

We have investigated the contactless electroreflectance (CER) properties of $In_{0.5}(Ga_{1-x}Al_x)_{0.5}P$/GaAs double heterostructures grown by metal-organic chemical vapour deposition (MOCVD). The CER measurements on the sample were studied as a function of temperature, modulation voltage ($V_{ac}$), and dc bias voltage ($V_{bias}$). Five signals observed at room temperature are related to the GaAs, $In_{0.5}Ga_{0.5}P$, $In_{0.5}(Ga_{0.73}Al_{0.27})_{0.5}P$, $In_{0.5}(Ga_{0.5}Al_{0.5})_{0.5}P$, and $In_{0.5}(Ga_{0.2}Al_{0.8})_{0.5}P$ transitions, respectively. From the temperature dependence of CER spectrum, the Varshni coefficients and broadening parameters were determined and discussed. In addition, we found that the behavior of the CER amplitude for the reverse bias is larger than that of the forward.

• Applied Biological Chemistry
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• v.40 no.6
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• pp.519-524
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• 1997

As an investigation for utilization of ascidian tunic carotenoids as a food color additives, we attempted to collect the volatile thermal degradation compounds from ascidian tunic carotenoids. Oxygenate volatile compounds were extracted by simultaneous distillation and extraction/concentration apparatus and analyzed by gas chromatography and mass spectrometery. Total 63 compounds were identified and some of them were caused by thermal degradation. They included 1,3,5-trimethylbenzene, 3,5,5-trimethyl-3-cyclohexen-1-ol, 3,5,5-trimethyl-3-cyclohexen-1-one, 1,1,2,3-tetramethyl-2-cyclohexen-5-ol, 1,1,2,3-tetramethyl-2-cyclohexen-5-one, 2,3,4,4-tetramethyl-6-hydroxy-2-cyclohexene-1-one, 1,2,3,8-tetrahydro-3,3,6-trimethyl-1-naphtol, dihydroacetinidolide, ${\beta}-ionone$, 2-(1,1,5-trimethyl-3-hydroxy-5-cyclohexen-6-yl)-1-tolylethene, 2,6-dimethyl-8-(1,1,5-trimethyl-3-hydroxy-5-cyclohexen-6-yl)-1,3,5-octatriene-7-yne. Proposed mechanism of formation of some compounds as thermal degradation products of ascidian tunic carotenoids are provided.

• Electronics and Telecommunications Trends
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• v.34 no.6
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• pp.1-16
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• 2019

The paper presents five strategic opinions for promoting the fourth industry revolution through the supply of 5G additional frequency. The assessments are on the basis of 5G frequency utilization technologies and services, with reference to 3GPP 5G New Radio standards, after investigating the domestic 1G, 2G, 3G, 4G, and 5G mobile communication services as well as the use of mobile radio frequency and spectrum. The presented opinions contain the frequency supply of contiguous-wide bandwidth channels, harmonized frequency supply between licensed and unlicensed spectrum, the existing 4G frequency recycle for increasing 5G coverage and capacity, balance frequency supply in the multi-band for 5G services, and the development of 5G vertical frequency for industry. The aim is that the presented five strategic opinions can offer guidance for the upcoming plan of domestic 5G additional frequency supply.

• Journal of information and communication convergence engineering
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• v.20 no.1
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• pp.8-15
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• 2022

The new 5G radio technology (NR) can provide ultra-reliable low latency communications. The supporting 5G network infrastructure will move away from the previous point-to-point network architecture to a service-based architecture. 5G can provide three new things, i.e., wider channels, lower latency and more bandwidth. These will allow 5G to support three main types of connected services, including enhanced mobile broadband, mission-critical communications, and the massive Internet of Things (IoT). In 2015, the 5th generation (5G) mobile communication was officially approved by the International Telecommunication Union (ITU) as IMT-2020. Since then, 3GPP, the international organization responsible for 5G standards, is actively developing specifications for 5G technologies. 3GPP Release 15 provides the first full set of 5G standards, and the evolution and expansion of 5G are now being standardized in Release 16 and 17, respectively. This paper provides an overview of 3GPP 5G technologies and key services.

• The Journal of Korean Institute of Electromagnetic Engineering and Science
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• v.29 no.5
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• pp.353-358
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• 2018

We herein analyze the service traffic characteristics and spectrum of the 5G mobile communication and suggest the effective 5G network deployment method for 5G mobile communication services. The data rates of the 5G mobile communication are from several kbps (voice and IoT) up to 1 Gbps (hologram, among others). The 5G mobile communication services show the diverse cell coverage environments owing to the use of diverse service data rates and multiple spectrum bands. To effectively support the 5G mobile communication services, the network deployment requires the optimization of the service coverages for new service environments and multiple spectrum bands. Considering the 5G spectrum bandwidth debated at present, if the 5G services of 100 Mbps can be supported in the 200 m cell edge using the 3.5 GHz spectrum bands, the 5G services of the 1 Gbps hologram and 500-Mbps 4k UHD can be supported in the cell edges of 50 m and 100 m using the 28 GHz spectrum bands. Therefore, the 5G services can be supported effectively by the 5G network deployment using spectrum portfolio configurations to match the diverse 5G services and multiple bands.

• Journal of Nutrition and Health
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• v.38 no.5
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• pp.352-363
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• 2005

The previous extensive in vitro studies on the antioxidative activities of a number of Korean grains, vegetables, seaweeds and mushrooms, and the various combinations of these food source exhibited a wide range of antioxidative activities, and four food mixtures composed of 5 kinds of foods (5A, 5B, 5C and 5D) were designed from 16 selective foods showing. high antioxidant effect, in vitro, to find the good combinations for the meal planning. Mixture 5B or 5C contained very high levels of total flavonoid and polyphenol, and ethanol extract from 5A, 5B or 5C showed very strong inhibitory effects against in vitro $Fe^{2+}-induced$ lipid peroxidation and ethanol extract from 5B or 5C showed remarkable DPPH radical scavenging effect and lipid peroxide-protein conjugation inhibition effect. And in vivo study was also carried out with two mixtures (5B, 5C). Powders (P5B, P5C) or ethanol extracts (E5B, E5C) of these mixtures were supplemented to Sprague-Dawley rats fed on high fat $(15\%)-high$ cholesterol $(1\%)$ semipurified diet for 5 weeks. The total antioxidant power in serum was significantly higher in P5B, P5C, E5B and E5C groups than in high fat control group, and $ascorbate-Fe^{2+}-induced$ TBARS was significantly lowered by E5B supplementation in rat liver. In liver tissue, Cu, Zn-SOD activity was significantly higher in P5B and E5B groups than in high fat control group, while catalase or GSH-peroxidase (GPx) activity was not changed by any supplementations. In kidney, Cu, Zn­SOD activity was significantly higher in P5B group than in high fat control group, while GPx activity was not changed by any supplementations. Taken together, mixture 5B and 5C showed very strong antioxidative effects both in vitro and in vivo. Therefore, the ingredient Korean foods of 5B and 5C could be recommended to take a lot together for prevention from age-related chronic diseases.

• Journal of Mushroom
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• v.2 no.1
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• pp.28-32
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• 2004

This experiments was conducted to study on the substitute cotton wastes for ricestraw compost media on cultivation of Agaricus bisporus. This results were as follows. The results of yield according to the mixture rate of cotton wastes($4000{\sim}5500kg/198m^2$), rice hull(4.5%), chicken manure(50%), gypsume(1.5%), urea(2%), tobacco powder((2.5%), seasame meal(5%) and $MgSo_4$(5%) was effected to 57.2% increasement with 64.33kg in summer season, 65.21kg in winter season, 39.6kg in control, respectively. The results of yield according to the mixture rate of cotton wastes($4000{\sim}5500kg/198m^2$), cotton hull(1.25%), rice hull(4.5%), chicken manure(50%), gypsume(1.5%), urea(2%), cigarette powder(2.5%), seasame dregs(5%) and $MgSo_4$(5%) was effected to 62.3% increasement with 61.0kg in summer season, 62.3kg in winter season, 39.6kg in control, respectively. The results of yield according to the mixture rate of cotton wastes($2000{\sim}2500kg/198m^2$), cotton hull(($2000{\sim}2500kg/198m^2$), rice hull(2.5%), chicken manure(37.5%), gypsume(1.5%), urine(2%), cigarette powder((1.25%), seasame dregs(2.5%) and $MgSo_4$(3%) was effected to 40.4% increasement with 57.33kg in summer season, 58.34kg in winter season, 39.6kg in control, respectively.