• Title/Summary/Keyword: 4P's strategies

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A newborn with developmental delay diagnosed with 4q35 deletion and 10p duplication

  • Kim, Beom Joon;Jang, Woori;Kim, Myungshin;Youn, YoungAh
    • Journal of Genetic Medicine
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    • v.17 no.2
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    • pp.102-107
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    • 2020
  • We report the case of an infant with a 4q35.1 deletion with 10p duplication. This mutation is rarely reported in the literature and has been found to have variable clinical findings, often including developmental delay. In this case, the condition was detected by chromosomal microarray analysis after initial manifestation of a feeding problem and developmental delay. Minor dysmorphic features with abnormal neurological examination led to further evaluation. The father's chromosome complement was 46, XY, t(4;10)(q35;p12.2). Parental balanced translocation can go unrecognized, because affected individuals are often phenotypically healthy until they have fertility issues such as recurrent miscarriages or children with severe congenital disorders. Genetic diagnoses help to establish a clear family genetic background that permits the development of clear treatment strategies. Prenatal counseling can also help to understand the possible risks associated with pregnancy or future child planning.

Estimation of Protein Deposition Rate of Growing-Finishing Pigs Reared in Commercial Conditions in Korea

  • Kim, J.H.;Sohn, K.S.;Hynn, Y.;Han, In K.
    • Asian-Australasian Journal of Animal Sciences
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    • v.13 no.8
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    • pp.1147-1153
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    • 2000
  • A total of 9,540 pigs were evaluated for their growth performance to provide information on the development of different feeding strategies to support maximum rate of protein deposition (PD). Large variations in growth performance and protein deposition rate were found in the population used in this study (ADG from 701 to 974 g/day; ADFI from 1,726 to 2,498 g/day; Feed/gain from 2.10 to 2.90; Backfat thickness from 12.4 to 20.5 mm and PD rate from 103 to 153 g/day). It was found that ADG was positively correlated to PD ($R^2=0.9362$, p<0.0001) while FCR was negatively correlated to PD ($R^2=0.4031$, p<0.0001). Backfat thickness was negatively correlated to PD ($R^2=0.7024$, p<0.0001) and to ADG ($R^2=0.5096$, p<0.0001). The estimated lysine requirement based on PD rate also showed large variation (12.37 to 18.38 g/day true ileal digestible lysine on average between 25 and 100 kg), thus strongly indicated the need of separate feeding strategies for each group of pigs. When pigs were divided into three categories according to estimated whole body PD rate, the group of pigs with the highest PD rate grew faster by 6.3 and 13.9% than pigs with intermediate and low PD rate, respectively. Feed utilization was also more efficient in pigs with a high PD rate. It appeared that pigs with high PD rate maintained higher PD rate especially in the later stage of their life. Pigs with high PD rate require an extra amount of 1.2 and 2.4 g/true digestible lysine per day and 0.4 and 0.8% more lysine in the diet than pigs with intermediate and low PD rate during the growing-finishing period respectively. Results of this study suggest that there is a need for separate feeding strategies for individual group of pigs with different PD rate. It should be noted that average value for each group presented in this report is not the adequate amount for an animals potential for maximum PD rate. With recent development in growth modeling and access to computer technologies to facilitate computation, pork producers can easily estimate pigs protein deposition rate and thus can make their own feeding strategies.

Ego-resilience and Emotional Intelligence, Stress Coping Strategies & Nursing Student's Adjustment to College (간호대학생의 자아탄력성, 감성지능, 스트레스 대처방식과 대학 생활 적응)

  • Ko, Mi-Suk
    • The Journal of the Korea Contents Association
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    • v.15 no.10
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    • pp.280-291
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    • 2015
  • This study was done to identify the influence of ego-resilience, emotional intelligence and stress coping strategies on college adjustment in nursing students. The subjects consisted of 158 freshmen & sophomores attending three nursing colleges. The data were collected from October 27 to November 7, 2014, using self-report questionnaires. The data were analyzed using t-test, ANOVA, Pearson correlation and multiple regression with SPSS/WIN 21.0 program. A positive correlation was found for college adjustment with ego-resilience, emotional intelligence, stress coping strategies. In addition emotional intelligence, ego-resilience, school record, satisfaction with nursing major, personal relations, gender accounted for 53.9% of variance in college adjustment. The strongest predictor of college adjustment was emotional intelligence. The findings suggest that development of emotional intelligence and ego-resilience in nursing students is important to college adjustment. It is necessary to develop systematic management of the program to integrate the educational curriculum and extra-curricular activities.

Has Eco-friendly Management Influence on the Customer's Purchasing Intention at Franchise Korean-restaurant

  • Yoon, Tae-Hwan
    • Culinary science and hospitality research
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    • v.23 no.6
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    • pp.11-19
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    • 2017
  • The purpose of this article was to study the influence of eco-friendly management on customer's purchasing-intention at franchise Korean restaurants. In this research, factor analysis and multi regression analysis were used. Eco-friendly management was divided into 4 factors. Eco friendly service affected positively brand image (p<0.05). Energy saving positively affected brand image (p<0.005). Contribution to local society positively affected brand image (p<0.05). Menu composition affected the most positively brand image (p<0.001). At last, brand image had positive influence on purchasing intention (p<0.001). According to these results, we confirmed that the factors of eco friendly management influenced significantly on the customers' perception of brand image. As a result, food service corporations need to deal with the factors of eco friendly management efficiently. The findings of this research would help business management to build effective service marketing strategies and to satisfy the needs of customers at franchise Korean restaurants.

Influencing Factors on Presenteeism of Clinical Nurses (임상간호사의 프리젠티즘에 영향을 미치는 요인)

  • Yeom, Eun Yi;Jeong, Gye Seon;Kim, Kyoung Ah
    • Korean Journal of Occupational Health Nursing
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    • v.24 no.4
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    • pp.302-312
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    • 2015
  • Purpose: This study was conducted to identify the influencing factors of job stress, self-efficacy, and organizational culture to presenteeism in clinical nurses. Methods: A descriptive correlation research design was used for the this study. The subjects were 245 nurses working at the hospital in S, A and C City, from August $1^{st}$ to October $30^{th}$ 2014. Data were analyzed using t-test, ANOVA, $Scheff{\acute{e}}^{\prime}s$ test, stepwise multiple regression by SPSS 21.0 program. Results: Job impairment indicated a significant positive relationship to job stress (p=.009), health problem (p<.001), and indicated significant negative relationship to self-efficacy (p<.001), innovative-oriented (p<.001), affiliative-oriented (p=.002), task-oriented (p=.026) in organizational culture. Significant factors of influencing to presenteeism were self-efficacy (p<.001, ${\beta}=-.363$), culture of task-oriented (p<.001, ${\beta}=-.248$) in organizational culture, and health problem (p=.002, ${\beta}=.187$). Conclusion: Self-efficacy was defined as a variable to influence on presenteeism, and developing of strategies and program to strengthen self-efficacy and task-oriented of organizational culture in nursing is helpful to reduce the presenteeism of clinical nurses.

The Study of Strategies for acquisition of moving object location

  • Min, Kyoung-Wook;Jang, In-Seung;Park, Jong-Hyun
    • Proceedings of the KSRS Conference
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    • 2002.10a
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    • pp.111-116
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    • 2002
  • The types of service using location Information are being various and extending it's domain as wireless internet technology is developing and it's application part is widespread, so it is prospected that LBS (Location-Based Services) will be killer application in wireless internet services. This location information is basic and high value-added information, and this information services make prior GIS (Geography Information System) to be useful to anybody. The acquisition of this location information from moving object is very important part for these LBS. After this, when LBS is familiar to everybody, we can predict that LBS system load is so heavy for the acquisition of so many subscribers and vehicles. Moving object database (MODB) system manages objects like subscribes and vehicles that are moving and have telecommunication terminal checked one's location. MODB is consists of 4 part, moving object location acquisition part, moving object location storage part, moving object query processing part, and moving object application p art. In this MODB system, acquisition of moving object location part must provide guarantee location information as well as reduce telecommunication overhead. In this paper, we study of problems in acquisition a huge number o f moving objects location and design some acquisition strategies to reduce telecommunication overhead. And after implementation these strategies, we estimate performance of this system and quality of information.

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Validity and Reliability of a Korean version of Interpersonal Emotion Management Strategies Scale (한국어판 간호사의 대인관계 감정관리 전략 척도의 타당도와 신뢰도)

  • Woo, Hee-Yeong;Han, Jeong-Won
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.18 no.8
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    • pp.324-331
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    • 2017
  • This study consisted of methodological research verifying the validity and reliability of the Korean version of the interpersonal emotion management (IEM) strategies scale after translating and modifying the scale developed by Little et al. The study verified the content validity, construct validity, concurrent validity and reliability based on 189 nurses working at four hospitals in the Seoul and Gyeonggi region. In this study, the Korean version of the IEM strategies scale was comprised of four factors, with a total of 15 questions that included three regarding situation modification, three regarding attention deployment, four regarding cognitive change, and five on modifying emotional response. Furthermore, verification of concurrent validity revealed that the Korean version of the IEM strategies scale was a valid tool as the correlation of the emotional intelligence scale appeared as r=0.60 (p<0.001). The reliability verification showed four factors at Cronbach's ${\alpha}=0.84-90$, confirming that the Korean version of the tool in this study was very reliable.It is important to note that this study provided basic data for the development of educational programs that can effectively control the negative emotions of clinical nurses at the organization level.

A Methodological Approach on the Evaluation of Patient Satisfaction: Focused on the Importance Performance Analysis(IPA) (환자만족도 평가에 대한 방법론적 접근: IPA기법을 중심으로)

  • Park, Jae-San
    • Health Policy and Management
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    • v.18 no.3
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    • pp.1-17
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    • 2008
  • The measurement and management of patient satisfaction has become one of the key issues in the last two decades. Hospitals must thoroughly understand the needs of their customers and design products and health services that meet and exceed their expectations. The importance-performance analysis(IPA) is a widely used analytical technique that yields strategies for managing customer satisfaction in a variety of applications. IP A is a two-dimensional grid based on customer-perceived importance of quality attributes and attribute performance. Depending on the interplay of these two dimensions, four strategies can be derived. The aim of this study is to develop the management strategies for improving patient satisfaction in university hospitals using the I-P analysis. The attributes on inpatient service quality in 4 university hospitals was investigated using the Martilla and James(l977)' s a mean adjusted I-P grid where the axes of the grid cross at the average rating point of all items. The patient satisfaction questionnaires were completed by 600 hospital inpatients. The main statistical methods are path analysis and IPA with SPSS 12.0 and AMOS 4.0 statistical softwares. The two attributes, physician and medical service, administrative staff kindness attributes position in first quadrant(Keep Up the Good domain). The nurse and nursing service attributes position in second quadrant(Possible Overkill domain). The two attributes, convenience of check-in service, facilities and physical environment position in third quadrant(Low Priority domain). Finally the quality of inpatient service(food etc.) attributes position in fourth quadrant(Concentrate Here domain). These findings show various implications on the development of strategies in university hospitals in the future. It was determined that quality of inpatient service(food etc.) need to concentrate more on investments. These investments include a taste, price, proper provision of food service and quick response of pain management. A low priority was given to investment in streamlining the check-in process of inpatient and hospital facilities and physical environment in the long run.

A Study on the Stress and Coping with Farm Work of Rural Women (여성농업인의 농작업 스트레스와 대처방법에 관한 연구)

  • 조현숙;김경미;최규련
    • Korean Journal of Rural Living Science
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    • v.10 no.2
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    • pp.37-51
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    • 1999
  • The objectives of this study were to understand the working stress of rural women and their coping strategies, and to provide basic data related with rural welfare policy. The data were obtained through 318 samples of rural women under sixty years old who work full-time at their farms with their husbands. The questionnaire employed Likert-type scale with four-point, and then the data were analyzed by statistical methods of frequency, percentage, mean score, analysis of variance, t-test and Duncan test through SAS program. The significance level was p < .05. The results of this study are as follows ; 1) The average stress level of rural women was over 2.9 points out of 4. 2) The stress level showed meaningful correlation with such variables as age, education, perception on economic status, and recognition by their husbands and other family members. The rural women who are over forty years old, below high school, disregarded from their family members were marked high stress level. 3) The level of rural women's stress coping strategies was quite as low as 1.95 out of 4. 4) The level of coping strategies showed meaningful correlation with such socio-demographic variables as age, perception on economic status and job satisfaction level. Those who aged over 40, perceives low economic staus, lives together with husbands'parents, and shows “average” job satisfaction scored significantly lower coping strategy levels. 5) The level of stress didn't indicate significant relation with the type of coping strategy.

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Cancer Activation and Polymorphisms of Human Cytochrome P450 1B1

  • Chun, Young-Jin;Kim, Donghak
    • Toxicological Research
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    • v.32 no.2
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    • pp.89-93
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    • 2016
  • Human cytochrome P450 enzymes (P450s, CYPs) are major oxidative catalysts that metabolize various xenobiotic and endogenous compounds. Many carcinogens induce cancer only after metabolic activation and P450 enzymes play an important role in this phenomenon. P450 1B1 mediates bioactivation of many procarcinogenic chemicals and carcinogenic estrogen. It catalyzes the oxidation reaction of polycyclic aromatic carbons, heterocyclic and aromatic amines, and the 4-hydroxylation reaction of $17{\beta}$-estradiol. Enhanced expression of P450 1B1 promotes cancer cell proliferation and metastasis. There are at least 25 polymorphic variants of P450 1B1 and some of these have been reported to be associated with eye diseases. In addition, P450 1B1 polymorphisms can greatly affect the metabolic activation of many procarcinogenic compounds. It is necessary to understand the relationship between metabolic activation of such substances and P450 1B1 polymorphisms in order to develop rational strategies for the prevention of its toxic effect on human health.