• Korean Journal of Microbiology
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• v.24 no.3
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• pp.221-227
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• 1986

The strain of Aspergillus nidulans carring a uvsH mutation which had been shown to be absolutely required for UV or 4-NQO induced mutagenic processes was studied on mitotic recombinational behaviour. Although the effect of uvsH locus on spontaneous mitotic crossing over between fpB37 and centromere was not considerable, UV-induced intergenic recombination did not occur in uvsH/uvsH homozygotic diploid. In case of gene conversion at riboflavin locus between a pair of non-complementary alleles, riboA1 and riboA3, the uvsH mutation was not concerned with that process occurred spontaneously or induced by UV irradiation. When the cells were irradiated by UV light, high degrees of aneuploid productions were detected in diploid homozygous for uvsH as compared with wild type, while much difference was not found during normal growth.