• 한국융합학회논문지
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• 제9권1호
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• pp.433-440
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• 2018

FDG PET 영상에서 MTV는 종양의 전체 대사정도를 반영하여 종양의 체적을 나타낸다. 하지만 MTV는 영상재구성의 영향을 받게 된다. 본 연구의 목적은 팬텀실험을 통하여 영상재구성에 따라 SUVmax의 역치 값을 달리하여 실제 체적과 MTV의 상관관계를 평가해보고자 하였다. NEMA IEC Body 팬텀에 $^{18}F-FDG$를 구와 배후 방사능의 비율(4:1, 8:1, 10:1, 20:1)이 되도록 주입 후 영상을 획득하였다. 획득한 영상에 4가지 방법(OSEM3D, OSEM3D+PSF, OSEM3D+TOF, OSEM3D+TOF+PSF)으로 영상을 재구성한 후 다양한 SUVmax 역치 값을 적용하여 MTV의 변화를 비교해 보았다. 전반적으로 SUVmax 역치 값이 증가 할수록 MTV가 감소하였으며, 구와 배후방사능 비율이 증가할수록 동일한 SUVmax 역치 값에서 MTV가 감소하였다. PSF와 TOF+PSF재구성영상에서 40% 역치 값, OSEM3D와 TOF 재구성 영상에서는 45% 역치 값을 적용하였을 때 팬텀의 실제체적과 MTV의 높은 상관관계를 보였다. 이번 연구결과를 통하여 영상재구성에 따라 MTV 측정에 기초적인 자료로 제공되어 질 것으로 사료된다.

• 한국통신학회논문지
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• 제31권4C호
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• pp.381-390
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• 2006

본 논문에서는 비 교정 영상에서 3장의 평면 패턴 영상들을 위치시켜, 한 장의 영상으로 찍어 얻은 영상으로부터 이들 평면 패턴 영상 간에 호모그래피(homography)로 카메라 교정을 하는 새로운 기법이 제안된다. 비교정 영상에서 3차원 재구성을 하려면 카메라 교정이 필수적이다. 제안된 방법은 대상 영상내에 존재하는 패턴 영상 간에 호모그래피를 계산함으로써, 3차원 재구성 시, 보다 쉽고 간단히 구현한다. 실험 결과는 제안된 방법(한 장내에 3장의 패턴영상 사용에 의한 카메라 교정법이 기존 방법(3장의 패턴영상 사용에 비해 매우 유용함을 확인한다. 또한, 비 교정 입력 영상에서 제안된 알고리즘을 이용한3차원 재구성의 예로 증명한다.

• Journal of Microbiology and Biotechnology
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• 제14권3호
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• pp.576-583
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• 2004

GERI-155 is a macrolide antibiotic containing two deoxyhexose molecules and shows antimicrobial activities against Gram-positive bacteria. Deoxysugar biosynthetic gene cluster of GERI-155 from Streptomyces sp. GERI-l55 genome was cloned. Four orfs were identified and a putative orf presumed to be the dTDP g]ucose-4,6-dehydratase gene was designated as gerE. GerE was expressed in E. coli by using a recombinant expression vector pHJ1. The expressed protein was purified from E. coli cell lysate by using ammonium sulfate fractionation, and DEAE-sepharose CL-6B and hydroxylapatite column chromatography. The molecular mass of the expressed protein correlated with the predicted mass that was deduced from the cloned gene sequence data. The recombinant protein was a homodimer with a subunit relative molecular weight of 39,000 Dalton. It was found to have dTDP-glucose 4,6-dehydratase activity and also found to be highly specific for dTDP-glucose as a substrate. The values of $K_{m} and V_{max}$ for dTDP-g]ucose were $32\mu$M and 335 nmol $min^{-1}$ (mg protein)^{-1}$, respectively. dTTP and dTDP were strong inhibitors of the protein. $NAD^+$, the coenzyme for dTDP-glucose 4,6-dehydratase, was tightly bound to the expressed protein.

• 한국정밀공학회지
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• 제10권4호
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• pp.81-93
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• 1993

The three dimensional(3D) shape reconstruction from two dimensional(2D) cross-sections can be completed through three main phases : the input compilation, the triangular grid formation, and the smooth surface construction. In the input compilation phase, the cross-sections are analyzed to exctract the input data required for the shape reconstruction. This data includes the number of polygonized contours per cross-section and the vertices defining each polygonized contour. In the triangular grid formation phase, a triangular grid, leading to a polyhedral approximations, is constructed by extracting all the information concerning contour links between two adjacent cross- sections and then performing the appropriate triangulation procedure for each contour link. In the smooth surface construction phase, a smooth composite surface interpolating all vertices on the triangular grid is constructed. Both the smooth surface and the polyhedral approximation can be used as reconstructed models of the object. This paper proposes a new method for reconstructing the geometric model of a 3D objdect from a sequence of planar contours representing 2D cross-sections of the objdect. The method includes the triangular grid formation algorithms for contour closing, one-to-one branching, and one-to-many braanching, and many-to-many branching. The shape reconstruction method has been implemented on a SUN workstation in C.

• Journal of electromagnetic engineering and science
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• 제10권4호
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• pp.199-205
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• 2010

This paper presents a tumor detection system for breast cancer that utilizes two-dimensional (2D) image reconstruction with microwave tomographic imaging. The breast cancer detection system under development consists of 16 transmit/receive antennas, and the microwave tomography system operates at 900 MHz. To solve a 2D inverse scattering problem, the method of moments (MoM) is employed for forward problem solving, and the simplex method employed as an optimization algorithm. The results of the reconstructed image show that the method accurately shows the position of a breast tumor.

• Maxillofacial Plastic and Reconstructive Surgery
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• 제42권
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• pp.28.1-28.4
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• 2020

Background: This clinical case presented a novel method of segmental mandible reconstruction using 3D-printed titanium implant with pre-mounted dental implants that was planned to rehabilitate occlusion. Case presentation: A 53-year-old male who suffered osteoradionecrosis due to the radiation after squamous cell carcinoma resection. The 3D-printed titanium implant with pre-mounted dental implant fixtures was simulated and fabricated with selective laser melting method. The implant was successfully inserted, and the discontinuous mandible defect was rehabilitated without postoperative infection or foreign body reaction during follow-ups, until a year. Conclusions: The 3D-printed titanium implant would be the one of the suitable treatment modalities for mandible reconstruction considering all the aspect of mandibular functions.

• 대한방사성의약품학회지
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• 제3권2호
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• pp.65-71
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• 2017

To assess the effects of filter and reconstruction of Cu-64 PET data on Siemens scanner, the various reconstruction algorithm with various filters were assessed in terms of spatial resolution, non-uniformity (NU), recovery coefficient (RC), and spillover ratio (SOR). Image reconstruction was performed using filtered backprojection (FBP), 2D ordered subset expectation maximization (OSEM), 3D reprojection algorithm (3DRP), and maximum a posteriori algorithms (MAP). For the FBP reconstruction, ramp, butterworth, hamming, hanning, or parzen filters were used. Attenuation or scatter correction were performed to assess the effect of attenuation and scatter correction. Regarding spatial resolution, highest achievable volumetric resolution was $3.08mm^3$ at the center of FOV when MAP (${\beta}=0.1$) reconstruction method was used. SOR was below 4% for FBP when ramp, Hamming, Hanning, or Shepp-logan filter were used. The lowest NU (highest uniform) after attenuation & scatter correction was 5.39% when FBP (parzen filter) was used. Regarding RC, 0.9 < RC < 1.1 was obtained when OSEM (iteration: 10) was used when attenuation and scatter correction were applied. In this study, image quality of Cu-64 on Siemens Inveon PET was investigated. This data will helpful for the quantification of Cu-64 PET data.

• 한국의학물리학회지:의학물리
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• 제28권1호
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• pp.27-32
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• 2017

We investigated the effect of a commercial iterative reconstruction technique (iDose, Philips) on the image quality and the dose calculation for the treatment plan. Using the electron density phantom, the 3D CT images with five different protocols (50, 100, 200, 350 and 400 mAs) were obtained. Additionally, the acquired data was reconstructed using the iDose with level 5. A lung phantom was used to acquire the 4D CT with the default protocol as a reference and the low dose (one third of the default protocol) 4D CT using the iDose for the spine and lung plans. When applying the iDose at the same mAs, the mean HU value was changed up to 85 HU. Although the 1 SD was increased with reducing the CT dose, it was decreased up to 4 HU due to the use of iDose. When using the low dose 4D CT with iDose, the dose change relative to the reference was less than 0.5% for the target and OARs in the spine plan. It was also less than 1.1% in the lung plan. Therefore, our results suggests that this dose reduction technique is applicable to the 4D CT image acquisition for the radiation treatment planning.

• Archives of Plastic Surgery
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• 제32권3호
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• pp.271-280
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• 2005

There are various types of flap in head and neck reconstruction. We chose the appropriate flap considering the indication and patient's condition. In case of conventional flaps, its type is decided according to the reconstruction site. In other words, the types of considerable flaps are limited in a way. But, perforator flaps can reduce donor limitation and harvest flaps depending on the condition of the recipient. Therefore, the flap is very useful for the head and neck reconstruction needed for 2-dimensional or 3-dimensional reconstruction. We report the 29 cases of perforator-based flap including 8 cases of latissimus dorsi perforator free flap, 5 thoracodorsal perforator free flap, 4 anterolateral thigh perforator free flap, 3 peroneal osteocutaneous perforator free flap and 9 submental perforator island flap for the head and neck reconstruction. Free flaps include 2 cases of chimeric pattern, 7 controlled resurfacing pattern, 4 3-D pattern, 3 dermoadiposal pattern, 1 folded pattern and 3 osteocutaneous pattern. The flaps were successfully used for the head and neck reconstruction. But one patient died during a follow up period because of the recurrence of tumor. Various perforator flaps(island/free pattern) can be highly competitive to the conventional flaps in the head and neck reconstruction, considering a thin character for resurfacing, more flexible and versatile option, variable composition, long pedicle with donor structures saved, and less prominent donor morbidity.

• 한국음향학회지
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• 제28권4호
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• pp.370-374
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• 2009

본 논문에서는 3차원 동영상을 구현하기 위하여 인체에 유해한 방사능 피폭량이 부챗살 형태의 Fan Beam 보다 상대적으로 적은 원추형 Cone Beam CT 시스템을 설계하였다. 설계된 시스템은 X-ray가 조사된 각도에서 획득한 데이터를 영상처리부로 전송하고 영상을 구성하는 계산 속도를 빠르게 하기 위하여 초월함수가 보다 적은 3단계 회전 행렬을 이용하여 3차원 영상을 구현하는 회전 기반법을 사용하였다. 본 연구에서는 3차원 영상을 구성하는 시간단축을 통해 초당 3~5장의 영상을 얻음으로써 3차원 동영상을 실시간으로 구현하였다.