• Animal cells and systems
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• v.5 no.4
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• pp.327-331
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• 2001

There is a critical developmental period during which brain sexual differentiation proceeds irreversibly under the influence of gonadal hormone. Recently, kinesin superfamily-associated protein 3 (KAP3) gene expressed during the 'critical period' of rat brain differentiation was identified by us (Choi and Lee, 1999). KAP3 functions as a microtubule-based motor that transports membranous organelles anterogradely in cells, including neurons (Yamazaki et al., 1996). mRNA level of KAP3 gene markedly increased before the initiation of puberty. Neonatal treatment of estrogen clearly inhibited the prepubertal increase in KAP3 mRNA level (Choi and Lee, 1999). In the present study, we aimed to investigate the effects of polychlorinated biphenyls (PCBs), as endocrine disruptors (EDs) on the expression of KAP3 gene during the 'critical period' of rat brain development. In our data, PCBs significantly decreased the expression of KAP3 gene in the fetal (day 17) and the neonatal (day 6 after birth in) male and female rat brains. The body weight and the breeding ability were significantly decreased in the PCBs-exposed rats compared with the control. These results showed that PCBs affect the transcriptional level of brain sexual differentiation related gene, KAP3, in the fetal and the neonatal rat brains. The maternal exposure to the PCBs may lead to toxic response in embryonic brain sexual differentiation and breeding ability after sexual maturation. This study indicates that KAP3 gene may be useful as a gene marker to analyze the molecular mechanism of toxic response in the animal brain development and sexual maturation exposed to PCBs.

• The Journal of Korean Academic Society of Nursing Education
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• v.2
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• pp.32-55
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• 1996

It was enacted 'Emergency Medical Act' in January, 1994 beginning the emergency medical service system from 1982, and while it was established the emergency medical department in junior college providing the detailed agenda about emergency medical technician and the regulation relative to the application of a law on the emergency medical act in 1995, the fire school and the National Medical Center are enforced the curriculum. It is very important subject faced for the construction of emergency medical system to produce a number of emergency medical technicians to be sufficient to the role of emergency aid. In this study it is analysed the training curriculum for the emergency medical technician and presented the improvement plans. 1. Though it needs the qualification level of first and second class in the selection process, the more important thing needs the detailed qualification level by term of one's service and the skills of business accomplishment. 2. In the examination management, (1) written examination is composed of the questions to understand how much faithfully they carry out the practical business as the emergency medical technicians, (2) it is added practical examination as the item to appraise the situation disposal ability. 3. It is necessary to prescribe the activity in the medical institution and ambulance arrangement through the development of 'Business Treatment Guide'. 4. For the regional balanced disposition of emergency medical personnel it is selected balanceably the educational institution by eight medical service areas, and considering the characteristics of region it is necessary to manage, in the practical business training course, another special course such as the mountains medical aid and sea medical aid. 5. In the period of education the first class needs the practical business training period of a certain period after passing examination, and the second class needs the extension of the period. 6. As the problems to improve in the curriculum [1] in the first class course (1) intensification of practical educaiton (2) reinforcement of curriculum (3) the development of standardized curriculum etc., [2] in the second class course (1) varieties of curriculum (2) intensification of basic first aid treatment education.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.19 no.1
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• pp.587-595
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• 2018

Countries that have been banned from building nuclear plants are becoming more tolerant in response to global warming and climate change. Thus, the construction of future nuclear plants will increase, and the competition will also intensify. A nuclear power plant has a long construction period compared with conventional construction projects. In order to gain a competitive advantage in nuclear power plant construction, the construction period must be decreased. Therefore, the purpose of this study is to develop an exterior wall form for a reactor containment building to reduce the construction time by increasing the height of the form. The structural safety, constructability, and economic feasibility were analyzed to assess the applicability of the proposed form. The proposed form was determined to be structurally safe. Furthermore, the construction period was shortened by reducing the duration of the construction units, and the total construction cost and interest were also reduced. Therefore, the proposed form could contribute to reducing the construction period for nuclear power plants.

• Journal of The Korean Association For Science Education
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• v.1 no.1
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• pp.15-27
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• 1978

First: The common points from "syllabus" period to that of "Course of study" are as follows: 1) with no introduction explained. the "Syllabus" or "Course of study" was made to be completed in accordance with the allotment of time (unit). 2) To teach how to rear animals and grow plants, and to make specimens with collected samples formed a great significant field of learning, which meant giving more emphasis on learning classification, life-centered education and basic field of learning than discipline-centered education. 3) The reason why the field of applied biology was emphasized on was that both periods had ideals in Common to educate persons more necessary and useful to the society than to major the pure academic field. 4) Both periods mainly dealt with problems of diseases, and physical health discussed all over the world in 1950's which accounts for necessity of the society to free from ignorance. Second; "The first curriculum period" and "the second one" are observed as follows: 1) The former took the unit (credit) system for the first time. It tried to lay down the conceptual hierarchy with "Biology I" and "II" divided, while "Biolgy I" is better systematized than "Biology II". 2) Discipline-centered education and structure fo knowledge are put more emphasis on especially in "the 2nd curriculum period". 3) And also in this period are included serious problems such as urgency of pollution, importance of nature conservation, population due to the development of industry. 'Third; With the recent curriculum laid down, experiments and teaching contents of subjects are put in harmony with each other and accordingly the process of Inquiry is laid emphasis on. Fourth; It is necessary to set up conceptual sequence and scope effectively in the curriculum.

• Journal of Animal Reproduction and Biotechnology
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• v.39 no.3
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• pp.201-211
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• 2024

Background: Hanwoo cattle farmers aim to improve calf production and reproductive efficiency. Recovery of the reproductive tract postpartum is a critical factor influencing the postpartum period and conception of breeding cows. This study aimed to precisely analyze the recovery process of the reproductive tract in primiparous Hanwoo postpartum and to establish recovery criteria. Methods: Ten primiparous Hanwoo cows were used in this study. After parturition, estrus was examined daily using visual observations and estrus detection patches. Ovarian recovery, cervical diameter, and uterine horn diameter were examined using ultrasonography four times per week. Results: The analysis revealed that the first estrus occurred at 19.1 ± 6.5 days postpartum, the first ovulation at 27.1 ± 4.5 days, and the first normal estrus cycle at 39.2 ± 6.4 days. The ovulation rate during the first estrus was 40%. A normal estrus cycle occurred in 11.1% of patients at the first ovulation. The cervix diameter recovered to 42.0 ± 3.5 mm and the uterine horn diameter to 34.4 ± 7.1 mm by 24 days postpartum, with the difference in uterine horn diameter recovering to 2.6 ± 1.2 mm by 31 days postpartum. Conclusions: This study can aid in determining the optimal breeding time for postpartum primiparous Hanwoo cow and provide foundational data for Hanwoo breeding studies.

• Journal of Korea Water Resources Association
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• v.45 no.4
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• pp.409-418
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• 2012

A modified standardized precipitation index was developed by considering the length of dry period and surface run-off effect. The official reports and newspapers on drought from 1973 to 2009 were quantified to evaluate drought indices. The developed index was evaluated using the receiver operating characteristic analysis. In order to suggest improved drought index, we cut the precipitation amount that may do not contribute the mitigation of drought and weight dry period by considering cumulative distribution, decile distribution of dry periods. Drought detection capability of the suggested index has improved by weighting of dry period effects and considering precipitation amounts contributing drought mitigation.

• Journal of Preventive Medicine and Public Health
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• v.39 no.3
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• pp.255-262
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• 2006

Objectives: This study is conducted to identify the cancer incidence in Gwangju during the 5-year period from 1998 to 2002 and to assess the completeness and validity of the cancer registry data during this time period. Methods: All cases that had a diagnosis of invasive cancer (ICD-10 sites C00-C97) during the study period were retrieved from the records of the Gwangju Cancer Registry (GCR), which theoretically includes all the cancer cases in Gwangju. All the cases during the study period were analyzed by gender, age group and cancer sites. The completeness (mortality/incidence ratio and age-specific incidence curve) and validity (histologic verification, primary site unknown, age unknown and death certificate only) of the cancer registry in Gwangju were analyzed by gender, age group and cancer sites for the 5-year period. Results: The overall cancer incidence was higher in the males than in the females (age-standardized incidence rates (ASR) 299.8 and 172.4 per 100,000, respectively). In males, the most common cancer was stomach (ASR: 65.8), followed by liver (ASR: 50.5), bronchus and lung (ASR: 50.5), colo-rectum (ASR: 26.7), oesophagus (ASR: 10.6), and bladder (ASR: 10.3) in descending order. In females, the most common cancer was stomach (ASR: 26.8), followed by thyroid (ASR: 20.7), breast (ASR: 20.4), cervix uteri (ASR: 14.3), bronchus and lung (ASR: 13.0), liver (ASR: 10.7) and colo-rectum (ASR: 17.2) in descending order. The overall quality (completeness and validity) of the cancer registry was at the in 'good' level. Conclusions: These results will be useful in the overall context of planning and evaluating of cancer control activities in Gwangju.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.18 no.4
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• pp.592-598
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• 2017

The purpose of this study is to suggest a new inspection period of ${\triangle}{\triangle}$ guided missiles by analyzing their reliability using field data. The ${\triangle}{\triangle}$ guided missile has an inspection period of five years which was determined using prediction data during its development process. However, from the analysis of its field data, it was shown that the inspection period could be extended to more than 18 years. Based on this result, a policy is proposed to reevaluate the inspection period by means of practical reliability tests.

• Journal of Plant Biotechnology
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• v.7 no.4
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• pp.225-231
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• 2005

Five day old cotyledon explants of Cucumber (Cucumis sativus L) cv Poinsett 76 were cocultivated with two Agrobacterium strains (EHA105 and LBA 4404) each carrying GUS as the reporter gene and npt-II as the selection marker gene in the T-DNA region of the vector. Transformed shoots were selected at 150 mg/L kanamycin. A two day cocultivation coupled with $20\;{\mu}M$ acetosyringone increased the frequency (8.2 and 15.4 shoots) of GUS expression in the shoots of transformed plant. Among the two Agrobacterium strains, EHA 105 performed better than LBA 4404 in bringing two-fold increase in transformation efficiency (14%) than LBA 4404 (7.4%). PCR analysis was done to confirm the integration of T-DNA into cucumber genome.

• Tribology and Lubricants
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• v.10 no.4
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• pp.51-58
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• 1994

Condition monitoring technology has recently been received much attention in the light of its significance on the maintenance of complex machineries such as turbines in power plants. Currently, turbines in power plants are maintained by scheduled overhaul based on the manufacturer's recommendations and the utility's experience. Although this preventive maintenance is known to be very effective, operators have less access to identify failure of elements when it happens between overhaul period. Therefore, in this study, a development of a on-line condition monitoring system through wear debris analysis of lubricating oils is aimed with a view to detecting abnormal wear behaviour of bearings and other wet-components at an early stage, allowing better outage scheduling and minimizing forced outages. For field application purposes, the on-line system developed was installed on the turbine of the No.4 unit at Ulsan Power Plant and its performance has been evaluated on site.