• 대한토목학회논문집
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• 제3권4호
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• pp.11-20
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• 1983

본(本) 연구(硏究)는 나선(螺旋)기둥의 신뢰성(信賴性) 설계규준(設計規準)을 고찰(考察)하고, Ellingwood가 제안(提案)한 신뢰성(信賴性) 해석(解析)과 신뢰성(信賴性) 설계규준(設計規準) 산정(算定) 알고리즘으로부터 실용적(實用的)인 알고리즘을 유도(誘導)하였다. Cornell의 MFOSM 이론(理論)에 의해 나선(螺旋)기둥의 불확실량(不確實量) 산정(算定)알고리즘을 유도(誘導)하여 저항(抵抗)의 불확실량(不確實量)을 산정(算定)했으며, 하중(荷重)의 불확실량(不確實量)은 우리의 실정(實情)을 고려한 적절한 값을 택(擇)하여 신뢰성(信賴性) 해석(解析) 및 신뢰성(信賴性) 설계규준(設計規準)을 산정(算定)했다. 현행(現行) WSD와 USD 설계법(設計法)의 신뢰성(信賴性) 수준(水準)을 분석(分析)하고 외국(外國)의 경우와 비교(比較) 검토(檢討)함으로써, 우리 실정(實情)에 적당한 목표신뢰성지수(目標信賴性指數) ${\beta}_0=3.5$를 택(擇)하여 LRFD 설계규준(設計規準)에 의한 하중일저항계수(荷重一抵抗係數)를 제안(提案)했으며, 신뢰성설계(信賴性設計)와 비슷한 신뢰성(信賴性)을 갖는 WSD의 철근(鐵筋)과 콘크리트의 허용응력(許容應力)을 산정(算定) 제안(提案)했다. 본(本) 연구(硏究)에서 제안(提案)한 신뢰성(信賴性) 설계규준(設計規準) 및 허용응력(許容應力)은 일정(一定)한 신뢰성(信賴性)을 주는 보다 합리적(合理的)인 설계(設計)가 됨을 알 수 있었다.

• 한국발생생물학회지:발생과생식
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• 제12권1호
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• pp.77-86
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• 2008

본 연구에서는 LIF의 첨가가 분리된 할구 유래의 생쥐 배아줄기세포 확립에 미치는 영향을 살펴보았다. 과배란 유도된 BDF1 생쥐로부터 2-세포기의 배아를 회수하여 각기 LIF가 첨가되지 않은 배양액과 1,000, 2,500, 5,000 U/mL의 LIF가 첨가된 배양액에서 포배기 배아까지 배양하였다. 배양된 포배기 배아는 차별화 염색 방법을 이용하여 내세포괴와 영양외배엽의 수를 계수하였다. 2,500 U/mL의 LIF 첨가 시 대조군($21.0{\pm}4.0$ vs. $15.9{\pm}5.0$, P<0.01)과 1,000 U/mL의 LIF를 처리한 군($21.0{\pm}4.0$ vs. $16.6{\pm}4.9$, P<0.05)에 비해서 내세포괴의 수가 유의하게(P<0.05) 증가하였다. 배아줄기세포주 확립 배양액으로는 FBS 대신 20% KSR과 0.01 mg/mL의 ACTH를 사용하였다. 2,500 U/mL의 LIF를 첨가 시 배아줄기세포 확립 효율이 36.7%(11/30)로 가장 높은 효율을 나타내었다. 이러한 배양 조건을 기본으로 하여 2-와 4-세포기 배아의 단일 할구를 분리하여 각기 21.4%(3/14)와 4.0%(1/20)의 효율로 단일 할구 배아줄기세포주를 확립할 수 있었다. 단일 할구로부터 확립된 배아줄기세포주와 이들에서 분화된 배아체는 세포면역학적 염색 방법과 RT-PCR 방법을 통해 그들의 미분화 특성과 삼배엽성 분화 특성을 확인할 수 있었다. 결론적으로 배양액에 LIF를 첨가하여 포배기 배아의 내세포괴 수를 증가시킬 수 있었으며, 분리된 할구의 배아줄기세포주 확립 효율을 향상시킬 수 있었다.

• 한국콘텐츠학회논문지
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• 제14권4호
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• pp.397-406
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• 2014

최근 현행 도시시설물 관리의 운영체계 미흡, 유지관리 정보의 연속성, 확장성 등의 문제점을 해결하기 위해, 기존 도시시설물 관리기능에 첨단 IT 기술을 융합하여 보다 효율적이고 다양한 서비스를 창출하고자 하는 추세이다. 따라서 본 연구는 우선적으로 BIM 기반 도시시설물 유지관리 동향을 조사 분석하고, 스마트 유지관리 기능 및 시설물 정보체계를 구성하여 환경을 구축하였다. 이후 BIM 기반의 도로 교량이나 터널과 같은 도시시설물 유지관리 시스템 개발에 필요한 고려사항을 시스템 운영 및 구축 측면에서 각각 도출하여 이를 바탕으로 BIM 기반 도시 시설물 유지관리 시스템 프레임워크를 제안하였다. 연구결과는 향후 유지관리 시스템 개발과 활용 시나리오 도출 및 적용 연구방향 설정에 기초자료로 활용될 수 있을 것이다.

• 한국지하수토양환경학회지:지하수토양환경
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• 제18권3호
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• pp.23-32
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• 2013

Korean groundwater quality standards were established in 1994, and revised in 2003 and 2010. The substances for which standards have been developed are classified into two groups, general pollutants, 4, and specific pollutants, 15. The standards have been applied to household water use, agriculture, aquaculture, and industrial use. However, there is no systematic methodology for either selecting candidate substances or establishing groundwater standards. We investigated various derivation methodologies for groundwater standards used by the European Commission and 27 member states and compared their methods for determining threshold values. The European Commission presented to their member states groundwater standards for two substances and a list of required substances for derivation of threshold values along with the member states. Interestingly, they first considered national background levels and then considered other criteria for water protection, such as drinking water standards, environmental quality standards, and irrigation standards. We suggest that Korean background levels in groundwater should be included in the methodology for establishing groundwater quality standards. These results may be useful in developing a systematic methodology for establishing Korean groundwater quality standards.

• 한국수자원학회논문집
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• 제44권11호
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• pp.889-902
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• 2011

본 연구에서는 한반도에서 발생했던 과거 가뭄사상의 정량적 평가를 위한 가뭄심도-지속기간-생기빈도(Severity-Duration-Frequency, SDF) 곡선을 유도하기 위해서 가뭄지수를 이용한 빈도해석을 실시하였다. 분석지점으로는 4대강 유역을 중심으로 하는 기상청 산하의 서울, 대전, 대구, 광주, 부산관측소를 선정하였으며 강수자료는 1974~2010년(37년)의 강수 자료를 이용하였다. 가뭄빈도해석에는 기상학적 가뭄지수인 SPI (Standardized Precipitation Index)를 선정하였으며 확률분포형에 대한 적합도 검정에서는 일반극치분포(GEV, Generalized Extreme Value)가 최적의 확률분포형으로 선정되었다. 가뭄지수의 빈도해석 통하여 유도된 주요 관측소별 SDF (Severity-Duration-Frequency) 곡선을 이용하여 과거의 주요 가뭄사상에 대한 재현기간을 제시하였으며 1994~1995년 가뭄의 경우 남부지방을 중심으로 하는 극심한 가뭄으로서 광주관측소에서는 50~100년, 부산관측소에서는 100~200년의 높은 재현기간을 나타내었다. 그밖에 1988~1989년 가뭄의 경우 서울관측소에서는 300년의 재현기간을 나타내었다.

• 한국학교수학회논문집
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• 제1권1호
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• pp.151-163
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• 1998

In mathematics education, teaching-learning activity can be divided largely into the understanding the mathematical concepts, derivation of principles and laws, acquirement of the mathematical abilities. We utilize various media, teaching tools, audio-visual materials, manufacturing materials for understanding mathematical concepts. But sometimes we cannot define or explain correctly the concepts as well as the derivation of principles and laws by these materials. In order to solve the problem we can use the computer. In this paper, character and movement state of various quadratic function graph types can be used. Using the computers is more visible than other educational instruments like blackboards, O.H.Ps., etc. Then, students understand the mathematical concepts and the correct quadratic function graph correctly. Consquently more effective teaching-learning activity can be done. Usage of computers is the best method for improving the mathematical abilities because computers have functions of the immediate reaction, operation, reference and deduction. One of the important characters of mathematics is accuracy, so we use computers for improving mathematical abilities. This paper is about the program focused on the part of "the quadratic function graph", which exists in mathematical curriculum the middle school. When this program is used for students, it is expected the following educational effect. 1, Students will have positive thought by arousing interests of learning because this program is composed of pictures, animations with effectiveness of sound. 2. This program will cause students to form the mathematical concepts correctly. 3. By visualizing the process of drawing the quadratic function graph, students understand the quadratic function graph structually. 4. Through the feedback, the recognition ability of the trigonometric function can be improved. 5. It is possible to change the teacher-centered instruction into the student-centered instruction. For the purpose of increasing the efficiencies and qualities of mathmatics education, we have to seek the various learning-teaching methods. But considering that no computer can replace the teacher′s role, tearchers have to use the CIA program carefully.

• Asian-Australasian Journal of Animal Sciences
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• 제28권11호
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• pp.1565-1572
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• 2015

Porcine embryonic stem cells (pESCs) have become an advantageous experimental tool for developing therapeutic applications and producing transgenic animals. However, despite numerous reports of putative pESC lines, deriving validated pESC lines from embryos produced in vitro remains difficult. Here, we report that embryo aggregation was useful for deriving pESCs from in vitro-produced embryos. Blastocysts derived from embryo aggregation formed a larger number of colonies and maintained cell culture stability. Our derived cell lines demonstrated expression of pluripotent markers (alkaline phosphatase, Oct4, Sox2, and Nanog), an ability to form embryoid bodies, and the capacity to differentiate into the three germ layers. A cytogenetic analysis of these cells revealed that all lines derived from aggregated blastocysts had normal female and male karyotypes. These results demonstrate that embryo aggregation could be a useful technique to improve the efficiency of deriving ESCs from in vitro-fertilized pig embryos, studying early development, and deriving pluripotent ESCs in vitro in other mammals.

• 한국학교수학회논문집
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• 제2권1호
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• pp.55-66
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• 1999

In mathematics education, teaching-learning activity can be divided largely into the understanding the mathematical concepts, derivation of principles and laws acquirement of the mathematical abilities. We utilize various media, teaching tools, audio-visual materials, manufacturing materials for understanding mathematical concepts. But sometimes we cannot define or explain correctly the concepts as well as the derivation of principles and laws by these materials. In order to solve the problem we can use the computer. In this paper, ′the process of the length of curve being equal to the sum of the vectors when intervals get smaller′ and ′the process of calculating volume of spinning curve by using definite integral.′ Using the computers is more visible than other educational instruments like blackboards, O.H.Ps., etc. Also it can help students with solving mathematical problems intuitively. Consequently more effective teaching-learning activity can be done. Usage of computers is the best method for improving the mathematical abilities because computers have functions of the immediate reaction, operation, reference and deduction. One of the important characters of mathematics is accuracy, so we use computers for improving mathematical abilities. This paper is about the program focused on the part of "the application of definite integral", which exists in mathematical curriculum the second and third grade of high school. When this study is used for students as assisting materials, it is expected the following educational effect. 1. Students will have precise concepts because they can understand what they learn intuitively. 2. Students will have positive thought by arousing interests of learning because this program is composed of pictures, animations with effectiveness of sound. 3. It is possible to change the teacher-centered instruction into the student-centered instruction. 4. Students will understand the relation between velocity and distance correctly because they can see the process of getting the length of curve by vector through the monitor. For the purpose of increasing the efficiencies and qualities of mathematics education, we have to seek the various learning-teaching methods. But considering that no computer can replace the teacher′s role, teachers have to use the CIA program carefully.

• 정보화연구
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• 제9권4호
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• pp.391-400
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• 2012

본 연구는 전구 탄도미사일 방어(TBMD)를 위한 협동교전의 기능아키텍처 도출에 관한 논문이다. TBMD는 다층으로 구성되며 네트워크 기반의 센서체계, 슈터체계, 그리고 전장관리체계로 구성되는 복합시스템이다. 협동교전능력은 대표적인 실시간 전장관리체계이며, 협동교전능력의 핵심기능은 협동교전이다. 협동교전은 두 개 이상의 분산된 자산의 통합을 통해 얻어진 시너지 효과로 위협을 제거하는 전투개념이다. 이러한 관점에서 본 논문은 개념 분석을 통해 TBMD의 협동교전 기능아키텍처를 제시하였으며, 이는 협동교전 기반의 TBMD 전투체계를 개발하기 위한 선행연구로서 수행되었다.

• KSII Transactions on Internet and Information Systems (TIIS)
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• 제15권8호
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• pp.2900-2922
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• 2021

In this paper, the power spectral density(PSD) for Multilevel Minimum Shift Keyed signal with modulation index h = 1/2 (M-ary MSK) are derived using the mathematical method of the Markov Chain model. At first, according to an essential requirement of the phase continuity characteristics of MSK signals, a complete model of the whole process of signal generation is built. Then, the derivations for autocorrelation functions are carried out precisely. After that, we verified the correctness and accuracy of the theoretical derivation by comparing the derived results with numerical simulations using MATLAB. We also divided the spectrum into four components according to the derivation. By analyzing these figures in the graphic, each component determines the characteristics of the spectrum. It is vital for enhanced spectral characteristics. To more visually represent the energy concentration of the main flap and the roll-down speed of the side flap, the specific out-of-band power of M-ary MSK is given. OMLCD(Optimum Maximum Likelihood Coherent Detection) of M-ary MSK is adopted to compare the signal received with prepared in advance in a code element T to go for the best. And M-ary MSK BER(Bit Error Rate) is compared with the same ary PSK (Phase Shift Keying) with M=2,4,6,8. The results show the detection method could improve performance by increasing the length of L(memory inherent) in the phase continuity.