• Journal of Korean society of Dental Hygiene
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• v.8 no.4
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• pp.219-228
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• 2008

The purpose of this study was to examine the oral health status and oral health care of adults using dental clinics and the relationship between their oral health state and oral health care. The subjects in this study were 219 patients who visited dental clinics in Gyeonggi province between February and April 2008. A dental checkup and survey were implemented, and SPSS 12.0 program was utilized to analyze the collected data. The findings of the study were as follows: 1. The DT, MT and FT rates of the respondents who used oral hygiene supplies respectively stood at 30.7, 24.6 and 24.6 percent, which were all low. The gaps between them and the others were statistically significant. The DMFT index of the users of oral hygiene supplies was 12.3, which was high, but the difference between them and the others was not statistically significant. 2. The DT rate of those who got a dental checkup on a regular basis stood at 20.8 percent, which was low. The gap between them and the others was statistically significant. Both the MT and FT rates of the former numbered 28.8 percent, which was low, but the gap between them and the others was statistically insignificant. The DMFT index of the respondents who got a regular dental checkup was 12.8, which was high, and the gap between them and the others was statistically significant. 3. The DT and FT rates of respondents who had ever had their teeth scaled respectively stood at 24.6 and 27.1 percent, which were both low, and the differences between them and the others were statistically significant. The MT rate of the former was 27.1 percent, which was low, but the gap between them and the others was statistically insignificant. The DMFT index of those who had ever had their teeth scaled was 12.2, which was high, and the gap between them and the others was statistically significant. The above mentioned findings suggested that there was a very close relationship between oral health care and oral health status. Therefore people in general should be encouraged to pay more attention to their own oral health care, and they should be well informed about how to take care of the oral cavity to promote their oral health.

• Korean Journal of Psychosomatic Medicine
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• v.26 no.2
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• pp.127-134
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• 2018

Objectives : This study aimed to identify the group with high risk of suicide in general hospital inpatient by comparing the depression, anxiety, and distress and their clinical characteristics. Methods : The study included all patients admitted to a general hospital between January 2016 and December 2017, and the final 41,249 patients were analyzed. Distress thermometer (DT) and hospital anxiety-depression scale (HADS) were used for emotional state evaluation. Group with high risk of suicide was defined as showing more than 4 in the DT and more than 8 in one of the two subscales (anxiety and depression) of the HADS. Results : Among the subjects, 3,603 patients (8.7%) met the high-risk criteria for suicide. The group with high risk of suicide experienced more severe pain than the control patient group, and it was found that there was more underlying disease. Patients who reported pain showed higher scores than those who reported no pain on the DT and HADS subscales. Conclusions : Group with high risk of suicide showed more severe pain and more underlying disease. Therefore, suicide prevention program specifically targeted for the group with high risk of suicide should be developed according to the risk of the patient evaluated at the time of the admission.

• Journal of the Korean Ceramic Society
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• v.25 no.2
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• pp.136-142
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• 1988

β-Al2O3, which is used for solid electrolyte membrances in sodium-sulfur batteries, was prepared by sol-gel process. Sodium-n-propoxide NaOC3H7 and aluminum-isopropoxide Al(OC3H7)3 were hydrolyzated in the solution at pH 3, pH 7, pH 9 and pH 11, respectively. The sol-gel processed samples were calcined at several temperature steps, respectively and analysed by thermal analyser(DT-TGA), infrared spectrum analyser and X-ray diffraction analyser. The gelling rate of solution at pH 7 was much higher than that of the solution at pH 3. Thermal exchanging behavior of the gels at pH 3 were similar to Na2O·Al2O3·6H2O and, above pH 7, were similar to Na2O·Al2O3·3H2O. When samples' composition ratio was 9.13 : 90.87 [NaOC3H7:Al(OC3H7)3] at pH 7, β-Al2O3 was formed at 1100℃.

• Journal of Ginseng Research
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• v.37 no.3
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• pp.273-282
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• 2013

The present study was designed to investigate the cardioprotective effects of Korean Red Ginseng extract (KRG) on isoproterenol (ISO)-induced cardiac injury in rats, particularly in regards to electrocardiographic changes, hemodynamics, cardiac function, serum cardiac enzymes, components of the myocardial antioxidant defense system, as well as inflammatory markers and histopathological changes in heart tissue. ISO (150 mg/kg, subcutaneous, two doses administered at 24-hour intervals) treatment induced significant decreases in P waves and QRS complexes (p<0.01), as well as a significant increase in ST segments. Moreover, ISO-treated rats exhibited decreases in left-ventricular systolic pressure, maximal rate of developed left ventricular pressure ($+dP/dt_{max}$) and minimal rate of developed left ventricular pressure ($-dP/dt_{max}$), in addition to significant increases in lactate dehydrogenase, aspartate transaminase, alanine transaminase and creatine kinase activity. Heart rate, however, was not significantly altered. And the activities of superoxide dismutase, catalase and glutathione peroxidase were decreased, whereas the activity of malondialdehyde was increased in the ISO-treated group. ISO-treated group also showed increased caspase-3 level, release of inflammatory markers and neutrophil infiltration in heart tissue. KRG pretreatment (250 and 500 mg/kg, respectively) significantly ameliorated almost all of the parameters of heart failure and myocardial injury induced by ISO. The protective effect of KRG on ISO-induced cardiac injury was further confirmed by histopathological study. In this regard, ISO treatment induced fewer morphological changes in rats pretreated with 250 or 500 mg/kg of KRG. Compared with the control group, all indexes in rats administered KRG (500 mg/kg) alone were unaltered (p>0.05). Our results suggest that KRG significantly protects against cardiac injury and ISO-induced cardiac infarction by bolstering antioxidant action in myocardial tissue.

• Journal of Ginseng Research
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• v.44 no.3
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• pp.483-489
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• 2020

Background: Korean Red Ginseng (KRG) has been known to possess many ginsenosides. These ginsenosides are used for curing cardiovascular problems. The present study show the protective potential of KRG against doxorubicin (DOX)-induced myocardial dysfunction, by assessing electrocardiographic, hemodynamic, and biochemical parameters and histopathological findings. Methods: Animals were fed a standard chow and adjusted to their environment for 3 days before the experiments. Next, the rats were equally divided into five groups (n = 9, each group). The animals were administered with KRG (250 and 500 mg/kg) for 10 days and injected with DOX (20 mg/kg, subcutaneously, twice at a 24-h interval) on the 8th and 9th day. Electrocardiography and echocardiography were performed to study hemodynamics. Plasma levels of superoxide dismutase, catalase, glutathione peroxidase, and malondialdehyde were measured. In addition, the dose of troponin I and activity of myeloperoxidase in serum and cardiac tissue were analyzed, and the histopathological findings were evaluated using light microscopy. Results: Administration of KRG at a dose of 250 and 500 mg/kg recovered electrocardiographic changes, ejection fraction, fractional shortening, left ventricular systolic pressure, the maximal rate of change in left ventricle contraction (-dP/dt_max), and left ventricle relaxation (-dP/dt_max). In addition, KRG treatment significantly normalized the oxidative stress markers in plasma, dose dependently. In addition, the values of troponin I and myeloperoxidase were ameliorated by KRG treatment, dose dependently. And, KRG treatment showed better histopathological findings when compared with the DOX control group. Conclusion: These mean that KRG mitigates myocardial damage by modulating the hemodynamics, histopathological abnormality, and oxidative stress related to DOX-induced cardiomyopathy in rats. The results of the present study show protective effects of KRG on cardiac toxicity.

• Molecules and Cells
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• v.23 no.1
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• pp.72-79
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• 2007

Demand for low-input sustainable crop cultivation is increasing to meet the need for environment-friendly agriculture. Consequently, developing genotypes with high nutrient use efficiency is one of the major objectives of crop breeding programs. This study was conducted to identify QTLs for traits associated with physiological nitrogen use efficiency (PNUE). A recombinant inbred population (DT-RILs) between Dasanbyeo (a tongil type rice, derived from an indica ${\times}$ japonica cross and similar to indica in its genetic make-up) and TR22183 (a Chinese japonica variety) consisting of 166 $F_8$ lines was developed and used for mapping. A frame map of 1,409 cM containing 113 SSR and 103 STS markers with an average interval of 6.5 cM between adjacent marker loci was constructed using the DT-RILs. The RILs were cultivated in ordinary-N ($N-P_2O_5-K_2O=100-80-80kg/ha$) and low-N ($N-P_2O_5-K_2O=50-80-80kg/ha$) (100 kg/ha) conditions. PNUE was positively correlated with the harvest index and grain yield in both conditions. Twenty single QTLs (S-QTLs) and 58 pairs of epistatic loci (E-QTLs) were identified for the nitrogen concentration of grain, nitrogen concentration of straw, nitrogen content of shoot, harvest index, grain yield, straw yield and PNUE in both conditions. The phenotypic variance explained by these S-QTLs and E-QTLs ranged from 11.1 to 44.3% and from 16.0% to 63.6%, respectively. The total phenotypic variance explained by all the QTLs for each trait ranged from 35.8% to 71.3%, showing that the expression of PNUE and related characters depends signify- cantly upon genetic factors. Both S-QTLs and E-QTLs may be useful for marker-assisted selection (MAS) to develop higher PNUE genotypes.

• Journal of Korean society of Dental Hygiene
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• v.1 no.2
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• pp.213-225
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• 2001

Objectives: This study was taken to investigate factors related to dental caries in deciduous teeth of preschool children. Methods : this study was completed by oral examination on 623 kindergarten pupils and questionnaire on their mothers in Sangju city from April 1 to May 20, 2001. Study design is Cross-sectional Study. Results: The mean values for decayed teeth indexed(dt index), filled teeth index(ft index), and decayed and filled teeth index(dft index) was 2.46, 1.85, and 4.30 respectively. 2.05 for girl was significantly lower than 2.77 of boy in gender (p<0.01). As child ren got older, values were higher(0.7 and 2.84 of three years old, 1.6 and 4.01 of four, 2.42 and 5.02 of five) in ft and dft index(p<0.001). Also, Mother age was almost same, that is, 4.12 dft value for 30~34 years was smaller than 6.17 for above forties(p<0.001). 2.07 and 4.68 for mothers who graduated from high school were higher than 1.36 and 3.34 for university in the ft and dft index(p<0.05), that is, the more they had a high educational level, the lower they got a values. Value 2.76 for children who had non cariogenic food was lower than 5.11 for those who had cariogenic food in dft index(p<0.001). In dft index, 3.82 of children who have learned the education on oral health from mother frequently have lower than 45 of children who have never learned (p<0.05). The ft value of children who had a snack food with mother(1.29) was a smaller than children had it at out of home(1.97)(p<0.05). The variables related 10 dft index were children and mothers age, educational level, and kinds of snack food (p<0.05). Conclusion : This study reveals that younger girl, younger mother, higher educational level, and non cariogenic foods showed lower dft index.

• Environmental Engineering Research
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• v.25 no.2
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• pp.222-229
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• 2020

Membrane assisted condenser is an innovative membrane operation that exploits the hydrophobic nature of microporous membranes to promote water vapor condensation and recovery. It can be used for water and chemicals recovery from waste gaseous streams. In this work, the testing of membrane condenser for water and ammonia recovery from synthetic streams (i.e., a saturated air stream with ammonia) simulating the plume of cooling tower is illustrated. The modeling of the process was carried out for predicting the membrane-based process performance and for identifying the minimum operating conditions for effectively recovering liquid water. The experimental data were compared with the results achieved through the simulations showing good agreement and confirming the validity of the model. It was found that the recovery of water can be increased growing the temperature difference between the plume and the membrane module (DT), the relative humidity of the plume (RH^plume) and the feed flow rate on membrane area ratio. Moreover, the concentration of NH₃ in the recovered liquid water increased with the growing DT, at increasing NH₃ concentration in the fed gaseous stream and at growing relative humidity of the feed.

• Food Science and Preservation
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• v.21 no.3
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• pp.301-307
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• 2014

The purpose of this study was to examine the potential of turmeric (Curcuma longa L.) to inhibit 7,12-dimethylbenz[a]anthracene (DMBA)-induced mammary carcinogenesis in rats. Female Sprague Dawley rats were fed a control diet (NC and DC) or an ethanol extract of turmeric (DT) diet until the end of the experiment. The rats in the DC and DT groups were administered a single dose of DMBA (50 mg/Kg) by oral gavages at 50 days of age. The turmeric ethanol extracts decreased the incidence and multiplicity of DMBA-induced mammary tumor. The turmeric ethanol extract significantly decreased the tumor cell proliferation. The turmeric also significantly decreased the tumor grade based on the degree of the tubule formation. The results suggest that the ethanol extract of turmeric has an inhibitory effect against mammary carcinogenesis, and that such chemopreventive effect may be related to the inhibition of the initiation and the proliferation of tumor cells.

• Asian Pacific Journal of Cancer Prevention
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• v.16 no.15
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• pp.6595-6597
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• 2015

Objective: To investigate short- and long-term treatment effects and side reactions of lobaplatin plus 5-Fu combined and concurrent radiotherapy in treating patients with inoperable middle-advanced stage esophageal cancer. Methods: Sixty patients with middle-advanced stage esophageal squamous cell cancer were retrospectively analyzed. All patients were administered lobaplatin (50 mg intravenously) for 2 h on day 1, and 5-Fu ($500mg/m^2$) injected intravenously from day 1 to 5 for 1 cycle, in an interval of 21 days for totally 4 cycles. At the same time, late-course accelerated hyperfractionated three-dimensional conformal radiotherapy was performed. Patients were firstly treated with conventional fractionated irradiation (1.8 Gy/d, 5 times/week, a total of 23 treatments, and DT41.4 Gy), and then treated with accelerated hyperfractionated irradiation (1.5 Gy, 2 times/d, a total of 27 Gy in 9 days, an entire course of 6-7 weeks, and DT 68.4Gy). Results: All patients completed treatment, including 10 complete response (CR), 41 partial response (PR), 7 stable disease (SD), and 2 progressive disease (PD). The total effective rate was 85.0% (51/60). Thirty-nine patients had an increased KPS score. One-, 2-, and 3-year survival rates were 85.3%, 57.5%, and 41.7%, respectively. The median survival time was 27 months. The adverse reactions included myelosuppression, which was mainly degree I and II. The occurrence rate of radiation esophagitis was 17.5%. No significant hepatic or renal toxicity was observed. Conclusion: Lobaplatin plus 5-Fu combined with concurrent radiotherapy is safe and effective in treating patients with middle-advanced stage esophageal cancer. However, this result warrants further evaluation by randomized clinical studies.