• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제45권3호
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• pp.123-128
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• 2019

Demineralized dentin matrix (DDM) has been used as a recombinant human bone morphogenetic protein-2 (rhBMP-2) carrier in many clinical trials. To optimize the clinical safety and efficacy of rhBMP-2 with DDM, efforts have been made to improve the delivery of rhBMP-2 by 1) lowering the administered dose, 2) localizing the protein, and 3) prolonging its retention time at the action site as well as the bone forming capacity of the carrier itself. The release profile of rhBMP-2 that is associated with endogenous BMP in dentin has been postulated according to the type of incorporation, which is attributed to the loosened interfibrillar space and nanoporous dentinal tubule pores. Physically adsorbed and modified, physically entrapped rhBMP-2 is sequentially released from the DDM surface during the early stage of implantation. As DDM degradation progresses, the loosened interfibrillar space and enlarged dentinal tubules release the entrapped rhBMP-2. Finally, the endogenous BMP in dentin is released with osteoclastic dentin resorption. According to the postulated release profile, DDM can therefore be used in a controlled manner as a sequential delivery scaffold for rhBMP-2, thus sustaining the rhBMP-2 concentration for a prolonged period due to localization. In addition, we attempted to determine how to lower the rhBMP-2 concentration to 0.2 mg/mL, which is lower than the approved 1.5 mg/mL.

• 한국재료학회:학술대회논문집
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• 한국재료학회 2012년도 춘계학술발표대회
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• pp.81.2-81.2
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• 2012

To fabricate a metal mold for injection molding, hot-embossing and imprinting process, mechanical machining, electro discharge machining (EDM), electrochemical machining (ECM), laser process and wet etching ($FeCl_3$ process) have been widely used. However it is hard to get precise structure with these processes. Electrochemical etching has been also employed to fabricate a micro structure in metal mold. A through mask electrochemical micro machining (TMEMM) is one of the electrochemical etching processes which can obtain finely precise structure. In this process, many parameters such as current density, process time, temperature of electrolyte and distance between electrodes should be controlled. Therefore, it is difficult to predict the result because it has low reliability and reproducibility. To improve it, we investigated this process numerically and experimentally. To search the relation between processing parameters and the results, we used finite element simulation and the commercial finite element method (FEM) software ANSYS was used to analyze the electric field. In this study, it was supposed that the anodic dissolution process is predicted depending on the current density which is one of major parameters with finite element method. In experiment, we used stainless steel (SS304) substrate with various sized square and circular array patterns as an anode and copper (Cu) plate as a cathode. A mixture of $H_2SO_4$, $H_3PO_4$ and DIW was used as an electrolyte. After electrochemical etching process, we compared the results of experiment and simulation. As a result, we got the current distribution in the electrolyte and line profile of current density of the patterns from simulation. And etching profile and surface morphologies were characterized by 3D-profiler(${\mu}$-surf, Nanofocus, Germany) and FE-SEM(S-4800, Hitachi, Japan) measurement. From comparison of these data, it was confirmed that current distribution and line profile of the patterns from simulation are similar to surface morphology and etching profile of the sample from the process, respectively. Then we concluded that current density is more concentrated at the edge of pattern and the depth of etched area is proportional to current density.

• 대한기계학회:학술대회논문집
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• 대한기계학회 2000년도 춘계학술대회논문집B
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• pp.789-794
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• 2000

The Paper studies the flow and heat transfer characteristics to a jet impinging at different oblique angles, to a plane surface by numerical methods. The flowfield and heat transfer rate associated with the oblique Impingement of an axisymmetric jet are of interest as a result of its presence in numerous technological Problems. For the computation of heat transfer rate, the standard ${\kappa}-{\varepsilon}$ and ${\kappa}-{\varepsilon}-\bar {{\upsilon}'^ 2}$ turbulent model were adapted. The accuracy of the numerical calculations was compared with various experimental data reported in the literature. ${\kappa}-{\varepsilon}-\bar {{\upsilon}'^ 2}$ model showed better agreement with experimental data than standard ${\kappa}-{\varepsilon}$ model in prediction of the turbulent intensity and the heat transfer rate. In the case of computation of flowfield, the study carries on the ${\alpha}=45$ deg, h/D=4.95. The jet Reynolds number based on the nozzle diameter(D), was 48,000. For the computation of heat transfer rate, the Re=20,000, the jet orifice-to-plate spacings(L/D) are 4, 6 and 10, and the angle between the axis of the jet orifice and the plate surface is set at 30, 45, 60, or 90 deg. For the smaller spacings, the near-peak Nusselt numbers are not significantly effected by the initial decreases in the Jet angle. The overall shape of the local Nusselt number x-axis profile is influenced by both the jet orifice-to-plate spacing and the jet angle.

• Journal of the Optical Society of Korea
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• 제10권3호
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• pp.105-111
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• 2006

A novel image quality evaluation method, which is based on combination of the rigorous grating diffraction theory and the ray-optic method, is proposed. It is applied for design optimization and, tolerance analysis of optical imaging systems implementing diffractive optical elements (DOE). The evaluation method can predict the quality and resolution of the image on the image sensor plane through the optical imaging system. Especially, we can simulate the effect of diffraction efficiencies of DOE in the camera lenses module, which is very effective for predicting different color sense and MTF performance. Using this method, we can effectively determine the fabrication tolerances of diffractive and refractive optical elements such as the variations' in profile thickness, and the shoulder of the DOE, as well as conventional parameters such as decenter and tilt in optical-surface alignments. A DOE-based 2M-resolution camera lens module designed by the optimization process based on the proposed image quality evaluation method shows ${\sim}15%$ MTF improvement compared with a design without such an optimization.

• Spatial Information Research
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• 제15권4호
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• pp.363-370
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• 2007

본 연구는 지형참조항법(TRN; Terrain Referenced Navigation)에 근거하는 헬리콥터 항법 시스템을 위한 기본 알고리즘을 개발하기 위해 수행되었다. 현재 본 연구에 위성 항법장치(GPS; Global Positioning System)로부터의 정보(X, Y, Z 좌표)는 비행체가 항로를 비행하는 중 매 92.8m의 수평거리로 환산하여 수신되는 것으로 가정하였다. 비행체는 3차원 직교 좌표 체계(Cartesian coordinate system)로 표현되는 수치지형모델(DTM; Digital Terrain Model)상에서 시점(Origination)-종점(Destination) 분석 기법에 의해 항로를 결정한다. 본 시스템은 우선 조종사에게 지형의 사전 인식을 위해 시점-종점 주변 3차원 지형도와 항로의 종단면도를 보여준다. 본 시스템은 직접적인 지상 충돌을 피하기 위해 지형 여유 층면(terrain clearance floor)의 개념을 도입, 기복 지형 표면에 일정 높이의 완충 공간을 설정한다. 만약 비행체가 항행 중 완충 공간에 접근하게 되면 본 시스템은 실시간으로 즉시 경고음과 메시지를 발한다(Matlab 메뉴를 사용하였음). 물론 헬리콥터의 이착륙 시에는 불필요한 경고를 발생시키지 않기 위해 완충 공간 조정은 가능하다. 수치지형모델은 (주)첨성대가 확보하고 있는 3초 간격의 DTM을 채택, 작성하였다.

• 한국정밀공학회지
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• 제31권3호
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• pp.199-205
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• 2014

We propose a new variant of lateral shearing interferometer with a tunable laser source that enables 3D surface profile measurements of freeform optics with high speed, high vertical resolution, large departure, and large field-of-view. We have verified the proposed technique by comparing our measurement result with that of an existing technique and measuring a representative sample of freeform optics. Moreover, we propose a new algorithm that is able to compensate the rotational inaccuracy.

• Journal of the Optical Society of Korea
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• 제19권3호
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• pp.265-271
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• 2015

We propose a reactive mesogen (RM) lens array to obtain good focusing behavior along with a short focal plane, where the focusing behavior is switchable according to the polarization state of incident light. Polarization-dependent focusing behavior is obtained using a planoconvex RM microlens array on a planoconcave isotropic lens template. Even though the sagitta of our RM lens is high, to obtain the short focal length, the RM layer can be aligned well by introducing a top-down alignment effect, using a nanogrooved template. The optical noise due to the $moir{\acute{e}}$ effect generated by the nanogrooves on the surface of the planoconvex RM layer can be removed simply by overcoating a thin RM layer, which is self-aligned by the geometric surface effect, without an additional alignment process. We demonstrate a hexagonal-packed RM lens array that has a very high fill factor and symmetric phase profile, for an ideal lens.

• 한국지반공학회논문집
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• 제30권5호
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• pp.17-24
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• 2014

본 논문에서는 국내 CFRD 사력존을 위한 1차원 전단파 속도 분포를 제안하였다. 이를 위해 선정된 3개의 댐 사면 8곳에서 수행된 표면파 시험 결과를 사용하였다. 다양한 원인에 의해 존재 가능한 사력존 물성치 공간 변동성에 의한 표면파 시험 결과의 불확실성을 고려하고자 시험에서 얻어진 개별 주상도들을 하모닉 웨이브릿 변환을 통해 공간-파수 영역에서 분석하였다. 이를 통해 전단파 속도 주상도에 존재하는 불확실성을 평가하였다. 논문에서 제안된 방법을 통해 사력존에 존재 가능한 1차원 전단파 속도 분포들을 생성하였으며, 생성된 1차원 전단파 속도 분포들을 사용하여 물성치 공간 변동성에 의한 불확실성이 고려된 국내 CFRD 사력존의 1차원 전단파 속도 분포를 결정하였다.

• Journal of the Optical Society of Korea
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• 제18권1호
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• pp.37-44
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• 2014

The use of a laser interferometer as a metrological tool in micro-optics measurement is demonstrated. A transmissive interferometer is effective in measuring an optical specimen having a high angle slope. A configuration that consists of an optical resolution of 0.62 micron is adapted to measure a specimen, which is a micro-Fresnel lens-shaped lenticular lens. The measurement result shows a good repeatability at each fraction of facets, however, a reconstruction of the lens shape profile is disturbed by a known problem of $2{\pi}$-ambiguity. To solve this $2{\pi}$-ambiguity problem, we propose a two-step phase unwrapping method. In the first step, an unwrapped phase map is obtained by using a conventional unwrapping method. Then, a proposed unwrapping method based on the shape modeling is applied to correct the wrongly unwrapped phase. A measured height of each facet is compared with a profile result measured by AFM.

• Ocean and Polar Research
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• 제34권3호
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• pp.325-335
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• 2012

It is well known that sound waves in the sea propagates under the influence of sea surface and bottom roughness, the sound speed profile, the water depth, and the density of sea floor sediment. In particular, an abrupt change of sound speed with depth can greatly affect sound propagation through an eddy. Eddies are frequently generated in the East Sea near the Korean Peninsula. A warm eddy with diameter of about 150 km is often observed, and the sound speed profile is greatly changed within about 400 m of water depth at the center by the eddy around the Ulleung Basin in the East Sea. The characteristics of low-frequency sound propagation across a warm eddy are investigated by a sound propagation model in order to understand the influence of warm eddies. The acoustic rays and propagation losses are calculated by a range-dependent acoustic model in conditions where the eddy is both present and absent. We found that low-frequency sound propagation is affected by the warm eddy, and that the phenomena dominate the upper ocean within 800 m of water depth. The propagation losses of a 100 Hz frequency are variable within ${\pm}15$ dB with depth and range by the warm eddy. Such variations are more pronounced at the deep source near the sound channel axis than the shallow source. Furthermore, low-frequency sound propagation from the eddy center to the eddy edge is more affected by the warm eddy than sound propagation from the eddy edge to the eddy center.