• 제목/요약/키워드: 3D micro structure

검색결과 227건 처리시간 0.032초

Preliminary Study on Effect of Lactiplantibacillus plantarum on Osteoporosis in the Ovariectomized Rat

  • Eun-Sun Jin;Ji Yeon Kim;JoongKee Min;Sang Ryong Jeon;Kyoung Hyo Choi;Shehzad Abid Khan;Gi-Seong Moon;Je Hoon Jeong
    • 한국축산식품학회지
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    • 제43권4호
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    • pp.712-720
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    • 2023
  • Osteoporosis is a growing global health concern primarily associated with decreased estrogen in postmenopausal women. Recently, some strains of probiotics were examined for potential anti-osteoporotic effects. This study intended to evaluate the impacts of Lactiplantibacillus plantarum MGE 3038 strain (MGE 3038) in ovariectomized rats. For this purpose, twelve weeks old female Wistar rats (n=21; 250-300 g) were divided into 3 groups; ovariectomy (OVX) group, OVX/MGE 3038 group and Sham group (control). In these groups; two went through respective OVX and one had daily MGE 3038 administration through oral gavage. Prior to 16 weeks after OVX, we collected blood samples and extracted the tibiae. We scanned the extracted tibiae by in-vivo micro-computed tomography (micro-CT) and evaluated pathology by hematoxylin and eosin (H&E) and Masson's trichrome staining. The serum levels of C-telopeptide of type I collagen (CTX), osteocalcin (OC), and the receptor activator of nuclear factor-κB ligand (RANKL) were examined. The OVX/MGE 3038 group showed increases in bone mineral density, trabecular bone volume, trabecular number, and trabecular thickness (Tb.Th), and a decrease in trabecular spacing than the OVX group. However, OVX/MGE 3038 group and control group were measurably comparable in Tb.Th. Micro-CT, H&E, and Masson's trichrome findings exhibited increased preservation and maintenance of trabecular bone structure in the OVX/MGE 3038 group in comparison to the OVX group. In serum, the levels of CTX, OC and RANKL were significantly different between the OVX and OVX/MGE 3038 groups. Taken together, L. plantarum MGE 3038 could be helpful for the treatment of osteoporosis.

Modeling of sulfate ionic diffusion in porous cement based composites: effect of capillary size change

  • Gospodinov, Peter N.
    • Computers and Concrete
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    • 제4권2호
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    • pp.157-166
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    • 2007
  • The paper considers a theoretical model to study sulfate ion diffusion in saturated porous media - cement based mineral composites, accounting for simultaneous effects, such as filling micro-capillaries (pores) with ions and chemical products and liquid push out of them. Pore volume change and its effect on the distribution of ion concentration within the specimen are investigated. Relations for the distribution of the capillary relative radius and volume within the composite under consideration are found. The numerical algorithm used is further completed to consider capillary size change and the effects accompanying sulfate ion diffusion. Ion distribution within the cross section and volume of specimens fabricated from mineral composites is numerically studied, accounting for the change of material capillary size and volume. Characteristic cases of 2D and 3D diffusion are analyzed. The results found can be used to both assess the sulfate corrosion in saturated systems and predict changes occurring in the pore structure of the composite as a result of sulfate ion diffusion.

Oscillator Design and Fabrication using a Miniatured Hairpin Resonator

  • Kim, Jang-Gu;Han, Sok-Kyun;Park, Hyung-Ha
    • 한국항해항만학회지
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    • 제28권4호
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    • pp.293-297
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    • 2004
  • In this papers, an S-band oscillator of the low phase noise property using a miniaturized micro-strip hairpin shaped ring resonator is presented The substrate has a dielectric constant $\epsilon_\gamma$=3.5, a thickness h=0.508 mm, and loss tangent $tan\delta$=0.002. A designed and fabricated oscillator shows low phase noise performance of 99. 71 dBc/Hz at 100 KHz offset frequency and of output power 19.584 dBm at center frequency 2.450 GHz. This circuit was fabricated with hybrid technique, but can be fully compatible with the MMIC due to its entirely planar structure.

Thermal Fatigue Behavior of 3D-Woven SiC/SiC Composite with Porous Matrix for Transpiration Cooling Passages

  • Hayashi, Toshimitsu;Wakayama, Shuichi
    • Advanced Composite Materials
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    • 제18권1호
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    • pp.61-75
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    • 2009
  • The effect of porous matrix on thermal fatigue behavior of 3D-orthogonally woven SiC/SiC composite was evaluated in comparison with that having relatively dense matrix. The porous matrix yields open air passages through its thickness which can be utilized for transpiration cooling. On the other hand, the latter matrix is so dense that the air passages are sealed. A quantity of the matrix was varied by changing the number of repetition cycles of the polymer impregnation pyrolysis (PIP). Strength degradation of composites under thermal cycling conditions was evaluated by the $1200^{\circ}C$/RT thermal cycles with a combination of burner heating and air cooling for 200 cycles. It was found that the SiC/SiC composite with the porous matrix revealed little degradation in strength during the thermal cycles, while the other sample showed a 25% decrease in strength. Finally it was demonstrated that the porous structure in 3D-SiC/SiC composite improved the thermal fatigue durability.

극한 환경 마이크로 화학센서용 다결정 3C-SiC 다이오드 제작과 그 특성 (Fabrication of polycrystalline 3C-SiC diode for harsh environment micro chemical sensors and their characteristics)

  • 심재철;정귀상
    • 한국전기전자재료학회:학술대회논문집
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    • 한국전기전자재료학회 2009년도 하계학술대회 논문집
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    • pp.195-196
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    • 2009
  • This paper describes the fabrication and characteristics of polycrystalline 3C-SiC thin film diodes for extreme environment applications, in which the this thin film was deposited onto oxidized Si wafers by APCVD using HMDS In this work, the optimized growth temperature and HMDS flow rate were $1,100^{\circ}C$ and 8sccm, respectively. A Schottky diode with a Au, Al/poly 3C-SiC/$SiO_2$/Si(n-type) structure was fabricated and its threshold voltage ($V_d$), breakdown voltage, thickness of depletion layer, and doping concentration ($N_D$) values were measured as 0.84V, over 140V, 61nm, and $2.7{\times}10^{19}cm^2$, respectively. To produce good ohmic contact, Al/3C-SiC were annealed at 300, 400, and $500^{\circ}C$ for 30min under a vacuum of $5.0{\times}10^{-6}$Torr. The obtained p-n junction diode fabricated by poly 3C-SiC had similar characteristics to a single 3C-SiC p-n junction diode.

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돼지 하악골의 micro-CT영상에서 추출한 3차원 골미세구조와 골강도 사이의 상관관계 (Relationship between trabecular strength and three-dimensional architecture in the pig mandible using microcomputed tomography)

  • 허경회;박무순;이원진;허민석;이삼선;최순철
    • Imaging Science in Dentistry
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    • 제35권3호
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    • pp.167-173
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    • 2005
  • Purpose : To investigate the relationship between three-dimensional (3D) bone imaging parameters and trabecular strength in the mandible. Materials and Methods : Bone specimens were obtained from the mandibles of five male pigs weighing around 110 kg each. Of those, 43 samples were selected for 3D analysis and measured by micro-computed tomography. The five morphometric parameters were trabecular thickness (Tb.Th), bone specific surface (BS/BV), percent bone volume (BV/TV), structure model index (SMI) and degree of anisotropy (DA). Through destructive mechanical testing, strength parameters were obtained. Results : BV/TV, SMI, BS/BV, and Tb.Th showed significant correlations with strength parameters. DA did not show any correlation with the other parameters. In multiple linear regression analysis, BV/TV alone explained $43\%$ of the variance in Young's modulus. By stepwise inclusion of SMI, the variance in the Young's modulus was better explained up to $52\%$. Conclusions : Predicting trabecular strength in the mandible through architectural analysis would be possible. Further study is needed to establish the tendency and variety of trabecular architecture and strength according to the locations within the mandible.

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Robust concurrent topology optimization of multiscale structure under load position uncertainty

  • Cai, Jinhu;Wang, Chunjie
    • Structural Engineering and Mechanics
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    • 제76권4호
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    • pp.529-540
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    • 2020
  • Concurrent topology optimization of macrostructure and microstructure has attracted significant interest due to its high structural performance. However, most of the existing works are carried out under deterministic conditions, the obtained design may be vulnerable or even cause catastrophic failure when the load position exists uncertainty. Therefore, it is necessary to take load position uncertainty into consideration in structural design. This paper presents a computational method for robust concurrent topology optimization with consideration of load position uncertainty. The weighted sum of the mean and standard deviation of the structural compliance is defined as the objective function with constraints are imposed to both macro- and micro-scale structure volume fractions. The Bivariate Dimension Reduction method and Gauss-type quadrature (BDRGQ) are used to quantify and propagate load uncertainty to calculate the objective function. The effective properties of microstructure are evaluated by the numerical homogenization method. To release the computation burden, the decoupled sensitivity analysis method is proposed for microscale design variables. The bi-directional evolutionary structural optimization (BESO) method is used to obtain the black-and-white designs. Several 2D and 3D examples are presented to validate the effectiveness of the proposed robust concurrent topology optimization method.

구형 빔 패턴 형성을 위한 MDAS-DR 안테나에 대한 연구 (A Study on the MDAS-DR Antenna for Shaping Flat-Topped Radiation Pattern)

  • 엄순영;윤재훈;전순익;김창주
    • 한국전자파학회논문지
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    • 제18권3호
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    • pp.323-333
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    • 2007
  • 본 논문에서는 구형 빔 패턴을 효율적으로 형성하기 위한 새로운 MDAS-DR 안테나 구조를 제안하였다. 안테나 구조는 크게 스택 마이크로스트립 패치 여기 소자, 다층 원형 도체 배열 소자들과 그 주위를 에워싸고 있는 유전체 링으로 구성된다. 다층 원형 도체 배열 구조는 스택 마이크로스트립 패치 여기 소자에 의해 방사 전력을 공급 받아 그 주변의 유전체 링과의 전기적 상호 결합 작용에 의해 원거리에서 구형 빔 방사 패턴을 형성할 수 있다. 유전체 링 구조의 설계 변수는 다층 원형 도체 배열 구조의 설계 변수와 더불어 구형 빔 패턴 형성에 중요한 설계 변수들로서 구형 빔 안테나를 위해 12개의 다층 원형 도체 배열과 유전율이 2.05인 테프론 유전체가 사용되었다. 제안된 안테나 구조의 유효성을 검증하기 위하여 10 GHz 대역$(9.6\sim10.4\;GHz)$에서 동작하는 안테 나를 설계하였으며, 시뮬레이션에는 삼차원 안테나 구조 해석에 적합한 상용 CST Microwave $Studio^{TM}$ 시뮬레이터가 사용되었다. 또한, 안테나 시제품을 제작한 후 무반사실 안테나 챔버에서 전기적 특성들을 측정하였다. 구형 빔 패턴 형성을 갖는 안테나 시제품의 측정 결과들은 시뮬레이션 결과들과 잘 일치하였으며, 측정 결과들로부터 MDAS-DR 안테나의 10 GHz에서의 측정 이득은 11.18 dBi이었으며, 최소한 8.0 % 대역 폭 내에서 약 $40^{\circ}$의 양호한 구형 빔 패턴을 형성함을 확인할 수 있었다.

Microtube Light-Emitting Diode Arrays with Metal Cores

  • Tchoe, Youngbin;Lee, Chul-Ho;Park, Junbeom;Baek, Hyeonjun;Chung, Kunook;Jo, Janghyun;Kim, Miyoung;Yi, Gyu-Chul
    • 한국진공학회:학술대회논문집
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    • 한국진공학회 2016년도 제50회 동계 정기학술대회 초록집
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    • pp.287.1-287.1
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    • 2016
  • Three-dimensional (3-D) semiconductor nanoarchitectures, including nano- and micro- rods, pyramids, and disks, are emerging as one of the most promising elements for future optoelectronic devices. Since these 3-D semiconductor nanoarchitectures have many interesting unconventional properties, including the use of large light-emitting surface area and semipolar/nonpolar nano- or micro-facets, numerous studies reported on novel device applications of these 3-D nanoarchitectures. In particular, 3-D nanoarchitecture devices can have noticeably different current spreading characteristics compared with conventional thin film devices, due to their elaborate 3-D geometry. Utilizing this feature in a highly controlled manner, color-tunable light-emitting diodes (LEDs) were demonstrated by controlling the spatial distribution of current density over the multifaceted GaN LEDs. Meanwhile, for the fabrication of high brightness, single color emitting LEDs or laser diodes, uniform and high density of electrical current must be injected into the entire active layers of the nanoarchitecture devices. Here, we report on a new device structure to inject uniform and high density of electrical current through the 3-D semiconductor nanoarchitecture LEDs using metal core inside microtube LEDs. In this work, we report the fabrications and characteristics of metal-cored coaxial $GaN/In_xGa_{1-x}N$ microtube LEDs. For the fabrication of metal-cored microtube LEDs, $GaN/In_xGa_{1-x}N/ZnO$ coaxial microtube LED arrays grown on an n-GaN/c-Al2O3 substrate were lifted-off from the substrate by wet chemical etching of sacrificial ZnO microtubes and $SiO_2$ layer. The chemically lifted-off layer of LEDs were then stamped upside down on another supporting substrates. Subsequently, Ti/Au and indium tin oxide were deposited on the inner shells of microtubes, forming n-type electrodes of the metal-cored LEDs. The device characteristics were investigated measuring electroluminescence and current-voltage characteristic curves and analyzed by computational modeling of current spreading characteristics.

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Fabrication of a Porous Copper Current Collector Using a Facile Chemical Etching to Alleviate Degradation of a Silicon-Dominant Li-ion Battery Anode

  • Choi, Hongsuk;Kim, Subin;Song, Hayong;Suh, Seokho;Kim, Hyeong-Jin;Eom, KwangSup
    • Corrosion Science and Technology
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    • 제20권5호
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    • pp.249-255
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    • 2021
  • In this work, we proposed a facile method to fabricate the three-dimensional porous copper current collector (3D Cu CC) for a Si-dominant anode in a Li-ion battery (LiB). The 3D Cu CC was prepared by combining chemical etching and thermal reduction from a planar copper foil. It had a porous layer employing micro-sized Cu balls with a large surface area. In particular, it had strengthened attachment of Si-dominant active material on the CC compared to a planar 2D copper foil. Moreover, the increased contact area between a Si-dominant active material and the 3D Cu could minimize contact loss of active materials from a CC. As a result of a battery test, Si-dominant active materials on 3D Cu showed higher cyclic performance and rate-capability than those on a conventional planar copper foil. Specifically, the Si electrode employing 3D Cu exhibited an areal capacity of 0.9 mAh cm-2 at the 300th cycles (@ 1.0 mA cm-2), which was 5.6 times higher than that on the 2D copper foil (0.16 mAh cm-2).