• Journal of the Korea Academia-Industrial cooperation Society
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• v.11 no.1
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• pp.141-150
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• 2010

In this paper, performance of a turbo-coded OFDM system is analyzed and simulated in a power line communication channel. Since the power line communication system typically operates in a hostile environment, turbo code has been employed to enhance reliability of transmitted data. The performance is evaluated in terms of bit error probability. As turbo decoding algorithms, MAP (maximum a posteriori), Max-Log-MAP, and SOVA (soft decision viterbi output) algorithms are chosen and their performances are compared. From simulation results, it is demonstrated that Max-Log-MAP algorithm is promising in terms of performance and complexity. It is shown that performance is improved 3dB by increasing the number of iterations, 2 to 8, and interleaver length of a turbo encoder, 100 to 5000. The results in this paper can be applied to OFDM-based high-speed power line communication systems.

• Environmental Analysis Health and Toxicology
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• v.13 no.3_4
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• pp.55-61
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• 1998

Glutathione-S-transferases (GSTs) detoxify electrophilic xenobiotics and reactive metabolites. Recently benzene-fused heterocycles have been shown to increase the total amount of hepatic GSTs in rats. Primarily this study aimed to determine the induction of GSTs by benzoazoles (BAs) including benzoxazole (BX), 2-methylbenzoxazole (M-BX), 2,5-dimethyl benzoxazole (D-BX), benzothiazole (BT), aminobenzothiazole (A-BT) and 2-mercaptobenzothiazole (M-BT) in rats. Hepatic cytosol and poly(A)$^+$ mRNA were prepared from rats after oral administration of BX, BT, M-BX, D-BX, A-BT and M-BT for 5 consecutive days at doses of 1 mmol/kg. Western immunoblot and northern blot analysis were conducted with rabbit anti-GST Ya, Yb$_1$, Yb$_2$, Yc antibodies and cDNA probes containing = 500 bps in the specific coding regions of Ya, Yb$_1$, Yb$_2$, Yc$_1$, and Yc$_2$, respectively. All BAs increased the amount of enzymes and mRNA levels of GSTs. BT was the most effective inducer of GSTs among the compounds examined in this study. Although A-BT and M-BT, the derivatives of BT, induced GSTs, these chemicals had lesser effect on induction of GSTs than BT. The derivatives of BX also induced less GSTs than the parent compound and the addition of methyl group to the benzene ring of BX reduced the induction of GSTs. BAs had better inductive effects on the class $\alpha$(Ya, Yc) than class $\mu$ GSTs (Yb$_1$, Yb$_2$). BAs enhanced mRNA levels of GSTs in parallel with the protein levels. These results indicate that 1) most of BAs induced various isozymes of GSTs, 2) the induction of GSTs appears to be correlated with the chemical structure of the derivatives, and 3) the expression of GST by BAs is presumably under the transcriptional regulation.

• Journal of the Korea Convergence Society
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• v.12 no.10
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• pp.45-53
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• 2021

In our technology-driven world, various methods for teaching in an educational venue or in a simulated environment have been suggested especially for computer and coding education. In particular, IoT related education has been made possible owing to the industrial developments that have occurred in various fields since the Fourth Industrial Revolution. The proposed model allows various IoT systems to be indirectly built; it provides an inexpensive learning method by applying a simulation system in a 3D environment. The model is implemented on Virtual Remote IO based on the Arduino platform, thereby reducing the cost of building an education system. In addition various education-related content can be provided to learners through such an indirectly developed system. Test code was written to check the consistency of an operation between the real system and the virtual system.

• Journal of Korean Library and Information Science Society
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• v.54 no.4
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• pp.151-178
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• 2023

At a time when libraries are attracting attention as institutions and spaces that can foster future capabilities, this study conducts a general survey of the current status of public library programs related to the future capabilities and investigate the social awareness on libraries and future capabilities through big data analysis. As a result, first, programs are being planned and provided with the keyword of future capabilities, but most of them are limited to makerspace programs, edutech programs, and experience programs. Also, the detailed types of programs are limited to 3D print, coding, AR, VR, etc. In addition, current library programs related to future capabilities are not subdivided by each competency, these programs are provided in the comprehensive sense of future competency. Second, in the awareness survey through big data analysis, education, future capabilities, and libraries were found to be highly frequent, and it was seen that library reading, books, culture, and programs were related to strengthening future capabilities. Accordingly, in the future, libraries need to develop and provide systematic programs to cultivate future capabilities, and there is also a need to develop future capabilities improvement programs that take the life cycle into account.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.12
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• pp.1790-1795
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• 2016

MicroRNAs (miRNAs) are highly conserved, short non-coding RNAs that regulate gene expression at the posttranscriptional level. Although many miRNAs are identified in muscles and muscle cells, their individual roles are still not fully understood. In the present study, we investigated a muscle highly-expressed miRNA, miR-127-3p, in C2C12 myoblasts and tissues of goats with different muscle phenotypes (Boer vs Wushan black goats). Our results demonstrated that i) miR-127-3p was extensively expressed in tissues of goats; ii) miR-127-3p was higher expressed in muscle, spleen, heart, and skin in the muscular goats (Boer goats) than the control (Wushan black goats). Then we further characterized the dynamical expression of miR-127-3p, MyoD, MyoG, Myf5, Mef2c, and Myosin in the proliferating and differentiating C2C12 myoblasts at day of 0, 1, 3, 5, and 7 in culture mediums. Especially, we found that miR-127-3p was significantly higher expressed in the proliferating than differentiating cells. Our findings suggest that miR-127-3p probably plays roles in the proliferation and differentiation of myoblasts, which further underlies regulation of muscle phenotype in goats.

• Korean Circulation Journal
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• v.54 no.5
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• pp.233-252
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• 2024

Background and Objectives: Myocardial ischemia-reperfusion injury (MIRI) refers to the damage of cardiac function caused by restoration of blood flow perfusion in ischemic myocardium. However, long non-coding RNA prostate androgen regulated transcript 1 (PART1)'s role in MIRI remain unclear. Methods: Immunofluorescence detected LC3 expression. Intermolecular relationships were verified by dual luciferase reporter assay. 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide, flow cytometry and transferase-mediated dUTP nick-end labeling (TUNEL) assays analyzed cell viability and apoptosis. The release of lactate dehydrogenase was tested via enzyme-linked immunosorbent assay (ELISA). Left anterior descending coronary artery surgery induced a MIRI mouse model. Infarct area was detected by 2,3,5-triphenyltetrazolium chloride staining. Hematoxylin and eosin staining examined myocardial injury. ELISA evaluated myocardial marker (creatine kinase MB) level. Results: PART1 was decreased in hypoxia/reoxygenation (H/R) induced AC16 cells and MIRI mice. PART1 upregulation attenuated the increased levels of Bax, beclin-1 and the ratio of LC3II/I, and enhanced the decrease of Bcl-2 and p62 expression in H/R-treated cells. PART1 upregulation alleviated H/R-triggered autophagy and apoptosis via miR-302a-3p. Mechanically, PART1 targeted miR-302a-3p to upregulate transcription factor activating enhancer-binding protein 2C (TFAP2C). TFAP2C silencing reversed the protected effects of miR-302a-3p inhibitor on H/R treated AC16 cells. We further established TFAP2C combined to dual-specificity phosphatase 5 (DUSP5) promoter and activated DUSP5. TFAP2C upregulation suppressed H/R-stimulated autophagy and apoptosis through upregulating DUSP5. Overexpressed PART1 reduced myocardial infarction area and attenuated MIRI in mice. Conclusion: PART1 improved the autophagy and apoptosis in H/R-exposed AC16 cells through miR-302a-3p/TFAP2C/DUSP5 axis, which might provide novel targets for MIRI treatment.

• Asian-Australasian Journal of Animal Sciences
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• v.29 no.5
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• pp.631-639
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• 2016

China has a long history of sheep (Ovis aries [O. aries]) breeding and an abundance of sheep genetic resources. Knowledge of the complete O. aries mitogenome should facilitate the study of the evolutionary history of the species. Therefore, the complete mitogenome of O. aries was sequenced and annotated. In order to characterize the mitogenomes of 3 Chinese sheep breeds (Altay sheep [AL], Shandong large-tailed sheep [SD], and small-tailed Hulun Buir sheep [sHL]), 19 sets of primers were employed to amplify contiguous, overlapping segments of the complete mitochondrial DNA (mtDNA) sequence of each breed. The sizes of the complete mitochondrial genomes of the sHL, AL, and SD breeds were 16,617 bp, 16,613 bp, and 16,613 bp, respectively. The mitochondrial genomes were deposited in the GenBank database with accession numbers KP702285 (AL sheep), KP981378 (SD sheep), and KP981380 (sHL sheep) respectively. The organization of the 3 analyzed sheep mitochondrial genomes was similar, with each consisting of 22 tRNA genes, 2 rRNA genes (12S rRNA and 16S rRNA), 13 protein-coding genes, and 1 control region (D-loop). The NADH dehydrogenase subunit 6 (ND6) and 8 tRNA genes were encoded on the light strand, whereas the rest of the mitochondrial genes were encoded on the heavy strand. The nucleotide skewness of the coding strands of the 3 analyzed mitogenomes was biased toward A and T. We constructed a phylogenetic tree using the complete mitogenomes of each type of sheep to allow us to understand the genetic relationships between Chinese breeds of O. aries and those developed and utilized in other countries. Our findings provide important information regarding the O. aries mitogenome and the evolutionary history of O. aries inside and outside China. In addition, our results provide a foundation for further exploration of the taxonomic status of O. aries.

• The Journal of The Korea Institute of Intelligent Transport Systems
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• v.3 no.1 s.4
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• pp.117-125
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• 2004

Space-time coding and modulation exploit the presence of multiple transmit antennas to improve performance on multipath Rayleigh fading channels. In this paper, we propose the Trellis-Coded Differential Space Time Modulation-OFDM system with multiple symbol detection. The Trellis-code perform the set partition with unitary group codes. The Viterbi decoder containing new branch metrics is introduced in order to improve the bit error rate (BER) in the differential detection of the Unitary differential space time modulation. Also, we describe the Viterbi algorithm in order to use this branch metrics. Our study shows that such a Viterbi decoder improves BER performance without sacrificing bandwidth and power efficiency.

• KSII Transactions on Internet and Information Systems (TIIS)
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• v.10 no.6
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• pp.2730-2747
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• 2016

Due to the limitation of the bandwidth resource and capture resolution of depth cameras, low resolution depth maps should be up-sampled to high resolution so that they can correspond to their texture images. In this paper, a novel depth map up-sampling algorithm is proposed by exploiting the fractal internal self-referential feature. Fractal parameters which are extracted from a depth map, describe the internal self-referential feature of the depth map, do not introduce inherent scale and just retain the relational information of the depth map, i.e., fractal transforms provide a resolution-independent description for depth maps and could up-sample depth maps to an arbitrary high resolution. Then, an enhancement method is also proposed to further improve the performance of the up-sampled depth map. The experimental results demonstrate that better quality of synthesized views is achieved both on objective and subjective performance. Most important of all, arbitrary resolution depth maps can be obtained with the aid of the proposed scheme.

• Journal of Microbiology
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• v.42 no.3
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• pp.205-210
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• 2004

The sequence coding for carboxymethylcellulase (CMCase, CelC) was isolated from the DNA of Salmonella typhimurium URl. Comparison between the deduced amino acid sequence of CelC (368 amino acid residues, Molecular mass 41 kDa) and that of the previously published CMCase revealed that this enzyme belongs to the cellulase family 8 and D. The protein was overproduced in Escherichia coli using T7 expression system, and its activity was confirmed by CMC-SDS-PAGE. When the overexpressed CelC protein was tested on cellulose-type substrates, the recombinant protein is able to degrade cellulose-type substrates, such as CM-cellulose, xylan, avicel, lichenan, and laminarin. Optimal temperature and pH for enzyme activity were found to be 50$^{\circ}C$ and pH 6.5, respectively.