• 한국의학물리학회지:의학물리
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• 제33권4호
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• pp.80-87
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• 2022

Purpose: Proton therapy has different relative biological effectiveness (RBE) compared with X-ray treatment, which is the standard in radiation therapy, and the fixed RBE value of 1.1 is widely used. However, RBE depends on a charged particle's linear energy transfer (LET); therefore, measuring LET is important. We have developed a LET measurement method using the inefficiency characteristic of an EBT3 film on a proton beam's Bragg peak (BP) region. Methods: A Gafchromic EBT3 film was used to measure the proton beam LET. It measured the dose at a 10-cm pristine BP proton beam in water to determine the quenching factor of the EBT3 film as a reference beam condition. Monte Carlo (MC) calculations of dose-averaged LET (LET_d) were used to determine the quenching factor and validation. The dose-averaged LETs at the 12-, 16-, and 20-cm pristine BP proton beam in water were calculated with the quenching factor. Results: Using the passive scattering proton beam nozzle of the National Cancer Center in Korea, the LET_d was measured for each beam range. The quenching factor was determined to be 26.15 with 0.3% uncertainty under the reference beam condition. The dose-averaged LETs were measured for each test beam condition. Conclusions: We developed a method for measuring the proton beam LET using an EBT3 film. This study showed that the magnitude of the quenching effect can be estimated using only one beam range, and the quenching factor determined under the reference condition can be applied to any therapeutic proton beam range.

• 한국의학물리학회:학술대회논문집
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• 한국의학물리학회 2002년도 Proceedings
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• pp.119-120
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• 2002

The aim is to urge the need of elaborate commissioning of 3D RTP system from the firsthand experience. A 3D RTP system requires so much data such as beam data and patient data. Most data of radiation beam are directly transferred from a 3D dose scanning system, and some other data are input by editing. In the process inputting parameters and/or data, no error should occur. For RTP system using algorithm-bas ed-on beam-modeling, careless beam-data processing could also cause the treatment error. Beam data of 3 different qualities of photon from two linear accelerators, patient data and calculated results were commissioned. For PDD, the doses by Clarkson, convolution, superposition and fast superposition methods at 10 cm for 10${\times}$10 cm field, 100 cm SSD were compared with the measured. An error in the SCD for one quality was input by the service engineer. Whole SCD defined by a physicist is SAD plus d$\sub$max/, the value was just SAD. That resulted in increase of MU by 100${\times}$((1_d$\sub$max//SAD)$^2$-1)%. For 10${\times}$10 cm open field, 1 m SSD and at 10 cm depth in uniform medium of relative electron density (RED) 1, PDDs for 4 algorithms of dose calculation, Clarkson, convolution, superposition and fast-superposition, were compared with the measured. The calculated PDD were similar to the measured. For 10${\times}$10 cm open field, 1 m SSD and at 10 cm depth with 5 cm thick inhomogeneity of RED 0.2 under 2 cm thick RED 1 medium, PDDs for 4 algorithms were compared. PDDs ranged from 72.2% to 77.0% for 4 MV X-ray and from 90.9% to 95.6% for 6 MV X-ray. PDDs were of maximum for convolution and of minimum for superposition. For 15${\times}$15 cm symmetric wedged field, wedge factor was not constant for calculation mode, even though same geometry. The reason is that their wedge factor is considering beam hardness and ray path. Their definition requires their users to change the concept of wedge factor. RTP user should elaborately review beam data and calculation algorithm in commissioning.

• 한국통신학회논문지
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• 제30권11A호
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• pp.1056-1063
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• 2005

본 논문에서는 기존 단극성 원 빔(one beam) 레이저 방식의 단점을 개선한 차량용 듀얼 빔 레이저 레이더 시스템을 설계하였다. 양극성 m-시퀀스를 두 개의 레이저 파장에 할당함으로써 2차원 OOC(orthogonal optical codes)와 유사한 특성을 갖도록 하고 수신부에서 두 개의 단극성 신호를 차동구조를 이용하여 양극성 신호로 합성하는 방법을 이용한 SNR 개선 방안을 제시하고 이의 성능을 분석하였으며, 시뮬레이션 결과, 제안하는 듀얼 빔 방식이 기존 원 빔 단극성 신호방식의 레이저 레이더 시스템에 비해 3dB의 SNR 개선이 가능함을 확인하였다. 또한 차등구조를 이용한 간단한 간섭제거 기법을 제시하였다. 제안한 방식은 단극성 광 신호를 기반으로 제안된 최근의 우수한 연구 결과들에 적용함으로써 3dB의 SNR 이득을 추가로 확보할 수 있는 장점이 있다.

• 분석과학
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• 제27권6호
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• pp.292-299
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• 2014

X-선 조형제인 이오프로마이드는 하천수에서 비교적 높은 검출 농도와 높은 검출 빈도로 검출되는 의약물질이다. 이오프로마이드를 전자선에 노출시킨 후 생성된 생성물의 화학 구조를 예측하였고 분해 효율을 측정하였다. 이오프로마이드를 소량 첨가시킨 수용액 시료를 전자선(UELV-10-10S, klysotrn, 10 MeV, 1 mA and 10 kW)에 노출시켰으며, LC/ESI-MS/MS 분석 후 질량스펙트럼을 해석함으로써 분해산물인 I_D_665와 I_D_663에 대한 화학적 구조 규명을 수행하였으며, 직렬식 질량분석에 의한 질량스펙트럼 토막이온의 생성 경로도 제안하였다. 0.3~5 kGy에 노출 시켰을 때 흡수선량의 증가에 따라서 30.5~98.4%가 분해되었으며, $0.5{\sim}100{\mu}g/kg$의 농도에서 0.3 kGy의 전자선으로 조사하였을 경우 97.8~30%가 분해되었다. 전자선량이 높을수록 그리고 분석물질이 낮은 농도일수록 전사선 조사에 의한 이오프로마이드의 분해효율은 증가하였다.

• 한국전자파학회논문지
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• 제14권4호
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• pp.413-420
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• 2003

본 논문에서는 위성통신용 능동 위상배열 안테나에서 주파수 스캔 효과에 의하여 발생하는 안테나 빔 패턴의 지향 오차를 보상하는 방법을 제안한다. 능동 위상배열 안테나가 두 개의 빔 패턴을 위하여 두 개의 배열이 직렬 연결되고 배열 수가 비대칭인 경우에, 두 빔의 적용 주파수가 다르고 주파수 간격이 크며 빔 폭이 좁고 스캔각이 크면 안테나는 주파수 스캔 효과에 의해 빔 지향 오차가 발생한다 제안되는 수식을 사용하면, 빔 지향오차 각을 예측하여 계산할 수 있으며 이를 보상하는 능동 위상배열 안테나의 위상제어 값을 계산할 수 있다. 본 논문에서는 첫째 층 32$\times$4 배열과 둘째 층 4$\times$2 배열 구조로부터 두 개의 안테나 빔을 가지고, 7.25 GHz~7.75 GHz 주파수 대역에서 두 빔의 주파수 편차가 최대 500 MHz(6.7 %)이며, 주파수 스캔 범위가 0$^{\circ}$~$\pm$35$^{\circ}$이고, 35.6 dBi 이득과 2.2$^{\circ}$의 3 dB 빔 폭을 가지는 능동 위상배열 안테나 시스템을 제작하고, 주파수 스캔효과에 의한 빔 지향 오차를 제안된 방법의 적용 전과 적용 후에 측정 비교하였다. 주파수 스캔 효과에 의한 빔 지향 오차는 보상 전에 최대 2.5$^{\circ}$였으나, 보상 후에는 최대 0.2$^{\circ}$오차로 감소하였다. 제안된 보상으로 안테나 시스템은 7 dB 신호감쇄가 보상되었다. 제안된 보상으로 능동 위상배열 안테나는 통신을 위한 목표 위성을 정확하게 지향할 수 있다.

• Journal of the Optical Society of Korea
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• 제5권3호
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• pp.99-109
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• 2001

This paper presents a phase-only modulation scheme for a three-dimensional (3-D) image matching system to improve optical efficiency of the system. The 3-D image matching system is based on the two mask heterodyne scanning. A hologram of the 3-D reference object is first created and then the phase of the hologram is extracted. The phase of the hologram is represented as one mask with the other mask being a plane wave. The superposition of each beam modulated by the two masks generated a scanning beam pattern. This beam pattern scans the 3-D target object to be recognized. The output of the scanning system gives out the correlation of the phase-only hologram of the reference object and the complex hologram of the target object. Since a hologram contains 3-D information of an object as a form of fringe pattern, the correlation of holograms matches whole 3-D aspect of the objects. Computer simulations are performed with additive gaussian noise and without noise for the complex hologram modulation scheme and the phase-only hologram modulation scheme. The computer simulation results show that the phase-only hologram modulation scheme improves the optical efficiency. Thus the system with the phase-only hologram modulation scheme is more robust than the system with the complex hologram modulation scheme.

• 대한기계학회논문집A
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• 제26권2호
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• pp.267-274
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• 2002

Using a flexible rotating beam test bed, experimental verification of a flexible multibody dynamic simulations for a rotating beam model has been carried out. The test bed consists of a flexible arm, harmonic driver reducer, AC servo motor and DSP board with PC. The mechanical ports of the test bed has been designed using 3D CAD program. For the simulation model, mass and moment of inertia of each part of the flexible rotating beam test bed are also obtained from 3D CAD model. In the flexible multibody dynamic simulations, the substructuring model has been established to capture nonlinear effects of the flexible rotating beam. Through the experimental verification, substructuring model provides better results than those from the linear model in the high speed rotation.

• 한국정밀공학회:학술대회논문집
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• 한국정밀공학회 2005년도 춘계학술대회 논문집
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• pp.1531-1534
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• 2005

Nano pattern is being utilized to produce micro optical components, sensors, and information storage devices. In this study, a study on nano pattern fabrication using raster-scan type Focused Ion Beam (FIB) milling is introduced. Because the intensity of ion beam has Gaussian distribution, the overlapping of the Gaussian beam results in a 3D pattern, and the shape of the pattern can be adjusted by variation of FIB milling parameters, such as overlap, ion dose, and dwell time. The Gaussian shape of single beam intensity has been investigated by experiment, and 3D nano patterns with pitch of 200nm generated by FIB is demonstrated.

• 한국정보디스플레이학회:학술대회논문집
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• 한국정보디스플레이학회 2002년도 International Meeting on Information Display
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• pp.395-398
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• 2002

The spherical aberration and optical integer (f) of the electron gun's main lens in color CRT is obtained, using electron beam trajectory. A spherical aberration is obtained from the relation between the object plane and the image of a beam trajectory. To analyze beam profile, 3rd and 1st order coefficient were obtained and used. It is shown that, in practice, they are applied to electron gun design.

• 한국전산유체공학회:학술대회논문집
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• 한국전산유체공학회 2008년도 춘계학술대회논문집
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• pp.581-584
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• 2008

A generation of a particle beam is the key technique in a flow cytometry that measures the fluorescence and light scattering of individual cell and other particulate or molecular analytes in biomedical research. Recent methods performing this function require a laborious and time-consuming assembly. In the present work, we propose a novel device for the generation of an axisymmetrical focusing beam of microparticles (3-D focusing) in a single capillary without sheath flows. This work uses the concept that the particles migrate toward the centerline of the channel when they lag behind the parabolic velocity profile. Particle focusing of spherical particles was successfully made with a beam diameter of about 10 ${\mu}$m. Proposed device provides crucial solutions for simple and innovative 3-D particle focusing method for the applications to the MEMS-based micro-flow cytometry. We believe that this device can be utilized in a wide variety of applications, such as biomedical/ biochemical engineering.