• Title/Summary/Keyword: 3D alignment

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3-D FEM Study on the Optical Characteristics of S-IPS Mode

  • Yang, Seung-Su;Park, Soon-Yeol;Won, Tea-Young
    • 한국정보디스플레이학회:학술대회논문집
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    • 2008.10a
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    • pp.231-234
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    • 2008
  • In this paper, we propose a novel electrode structure for superb transmittance in super in-plane switching (S-IPS) mode while keeping the features of the conventional SIPS mode such as the capability of initial LC alignment. The optimization of the electrode made it possible to enhance the light transmittance approximately by 14 % in comparison to the conventional S-IPS cell.

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3D-QSAR Studies of Tetraoxanes Derivatives as Antimalarial Agents Using CoMFA and CoMSIA Approaches

  • Liang, Taigang;Ren, Luhui;Li, Qingshan
    • Bulletin of the Korean Chemical Society
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    • v.34 no.6
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    • pp.1823-1828
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    • 2013
  • Tetraoxanes (1,2,4,5-tetraoxanes) have been reported to exhibit potent antimalarial activity. In the present study, the three dimensional-quantitative structure activity relationship (3D-QSAR) studies were performed on a series of tetraoxanes derivatives using comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) techniques. The best predictive CoMFA model with atom fit alignment resulted in cross-validated coefficient ($q^2$) value of 0.719, non-cross-validated coefficient ($r^2$) value of 0.855 with standard error of estimate (SEE) 0.335. Similarly, the best predictive CoMSIA model was derived with $q^2$ of 0.739, $r^2$ of 0.847 and SEE of 0.344. The generated models were externally validated using test sets. The final QSAR models as well as the information gathered from 3D contour maps should be useful for the design of novel tetraoxanes having improved antimalarial activity.

3D-QSAR Studies on Angiotensin-Converting Enzyme (ACE)Inhibitors: a Molecular Design in Hypertensive Agents

  • San Juan, Amor A.;Cho, Seung-Joo
    • Bulletin of the Korean Chemical Society
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    • v.26 no.6
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    • pp.952-958
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    • 2005
  • Angiotensin-converting enzyme (ACE) is known to be primarily responsible for hypertension. Threedimensional quantitative structure-activity relationship (3D-QSAR) models have been constructed using the comparative molecular field analysis (CoMFA) and comparative molecular similarity indices analysis (CoMSIA) for a series of 28 ACE inhibitors. The availability of ACE crystal structure (1UZF) provided the plausible biological orientation of inhibitors to ACE active site (C-domain). Alignment for CoMFA obtained by docking ligands to 1UZF protein using FlexX program showed better statistical model as compared to superposition of corresponding atoms. The statistical parameters indicate reasonable models for both CoMFA ($q^2$ = 0.530, $r^2$ = 0.998) and CoMSIA ($q^2$ = 0.518, $r^2$ = 0.990). The 3D-QSAR analyses provide valuable information for the design of ACE inhibitors with potent activity towards C-domain of ACE. The group substitutions involving the phenyl ring and carbon chain at the propionyl and sulfonyl moieties of captopril are essential for better activity against ACE.

Development of Cognition Character Model for Road Safety Facilities on Vertical Alignment Sections (종단선형구간에서의 도로안전시설물 인지특성 모형개발)

  • Lee, Soo-Beom;Kim, Jang-Wook;Kwon, Hyuk-Min
    • Journal of Korean Society of Transportation
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    • v.23 no.3 s.81
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    • pp.73-84
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    • 2005
  • Highway design criteria are considering roadway safety and smooth driving maneuver. However, a certain highway alignment within design criteria often leads drivers to undesirable situation due to the differences between the original intention of design criteria and the unintended result of drivers' cognition. The differences between them often result in traffic accidents. In order to reduce accident process, highway safety facilities are installed on those roadway sections. However, the relationship between highway environments and human factors has not been deeply studied in Korea. In this study. vertical roadway sections are constructed with 3-D graphical tools. This vertical roadway sections are simulated on a driving simulator in order to identify the differences of drivers' cognition on different roadway environments. Based upon the collected data from the driving simulator, canonical correlation analysis and canonical discriminant analysis of quantification theory II have been performed in order to figure out impacting factors on the degree of roadway safety. Also, based upon quantification theory I. the relationship between roadway safety facilities and the degree of safety has been analyzed.

A Proposal of Educational 3D Modelling Software Development Type Via User Experience Analysis of Open Source 3D Modelling Software (무료공개 3D모델링 소프트웨어 사용자 경험 분석을 통한 교육용 3D모델링 소프트웨어 개발유형 제안)

  • Lee, Guk-Hee;Cho, Jaekyung
    • Science of Emotion and Sensibility
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    • v.20 no.2
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    • pp.87-102
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    • 2017
  • With increasing interest in 3D printing, the interest in the 3D modelling training that should precede the 3D printing is increasing. However, the existing 3D modelling software is developed mostly by foreign brands. Thus, the interfaces are all in English. 3D modelling software training for Korean novices who are not familiar with these terms has constraints. This study aims to explore what to consider when developing a Korean model for 3D modelling educational software for 3D printing in the face of such reality. For this goal, after having novices with no experience in 3D modeling to perform a house building task using either 12D Design or Tinker CAD, we conducted a survey. It was found in the result that more users favored Tinker CAD over 123D Design, and the errors involved while working with the Tinker CAD were less than those with the 123D Design, and the ratio of people who completed the task with the Tinker CAD was higher than that with the 123D Design. In general discussion, an introductory level educational 3D modeling software development is proposed which utilize characteristics of Tinker CAD (easy modelling is possible by three-dimensional figures) and web-based method. Also, a beginner/intermediate level educational 3D modeling software development is proposed which utilize characteristics of 123D Design (with finer measurement manipulations and figure alignment) and Windows-based method.

Numerical simulation on structural behavior of UHPFRC beams with steel and GFRP bars

  • Yoo, Doo-Yeol;Banthia, Nemkumar
    • Computers and Concrete
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    • v.16 no.5
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    • pp.759-774
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    • 2015
  • This study simulates the flexural behavior of ultra-high-performance fiber-reinforced concrete (UHPFRC) beams reinforced with steel and glass fiber-reinforced polymer (GFRP) rebars. For this, micromechanics-based modeling was first carried out on the basis of single fiber pullout models considering inclination angle. Two different tension-softening curves (TSCs) with the assumptions of 2-dimensional (2-D) and 3-dimensional (3-D) random fiber orientations were obtained from the micromechanics-based modeling, and linear elastic compressive and tensile models before the occurrence of cracks were obtained from the mechanical tests and rule of mixture. Finite element analysis incorporating smeared crack model was used due to the multiple cracking behaviors of structural UHPFRC beams, and the characteristic length of two times the element width (or two times the average crack spacing at the peak load) was suggested as a result of parametric study. Analytical results showed that the assumption of 2-D random fiber orientation is appropriate to a non-reinforced UHPFRC beam, whereas the assumption of 3-D random fiber orientation is suitable for UHPFRC beams reinforced with steel and GFRP rebars due to disorder of fiber alignment from the internal reinforcements. The micromechanics-based finite element analysis also well predicted the serviceability deflections of UHPFRC beams with GFRP rebars and hybrid reinforcements.

Bouble Resonance Optical Pumping in the Transition 5S1/2-5P3/2-4D3/2, 5/2 of Rb Atoms (루비듐 5S1/2-5P3/2-4D3/2, 5/2 전이선에서의 이중공명 광펌핑 분광)

  • Moon, H.S.;Lee, L.;Kim, J.B.
    • Korean Journal of Optics and Photonics
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    • v.16 no.4
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    • pp.297-303
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    • 2005
  • We present the double resonance optical pumping(DROP) spectra according to the laser power, the polarization combination of lasers, and the alignment of lasers in the transition $5P_{3/2}-4D_{5/2}\;and\;5P_{3/2}-4D_{5/2}$ of $^{87}Rb.$ We observed obviously changing DROP spectrum according to the laser power in the transition $5P_{3/2}-4D_{5/2}$ involved the cycling transition. The laser power effects are attributed to the low optical-pumping-effect in the cycling transition. We observed changing DROP spectrum depending on the polarizations of the lasers. The laser polarization effects are attributed to the changing transition probability according to the polarizations of lasers. We compared the co-propagation with the counter-propagation and the spectral linewidths were 12.2 MHz and 6.9 MHz, respectively.

Three Dimensional Quantitative Structure-Activity Relationship Analyses on the Fungicidal Activities of New Novel 2-Alkoxyphenyl-3-phenylthioisoindoline-1-one Derivatives Using the Comparative Molecular Similarity Indices Analyses (CoMSIA) Methodology Based on the Different Alignment Approaches (상이한 정렬에 따른 비교분자 유사성 지수분석(CoMSIA) 방법을 이용한 새로운 2-Alkoxyphenyl-3-phenylthioisoindoline-1-one 유도체들의 살균활성에 관한 3차원적인 정량적 구조와 활성과의 관계)

  • Sung, Nack-Do;Yoon, Tae-Yong;Song, Jong-Hwan;Jung, Hoon-Sung
    • The Korean Journal of Pesticide Science
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    • v.9 no.1
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    • pp.26-34
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    • 2005
  • 3D-QSAR studies for the fungicidal activities against resistance phytophthora blight (RPC; 95CC7303) and sensitive phytophthora blight (Phytopthora capsici) (SPC; 95CC7105) by a series of new 2-alkoxyphenyl-3-phenylthioisoindoline-1-one derivatives (A & B) were studieded using comparative molecular similarity indices analyses (CoMSIA) methodology. From the based on the results, the two CoMSIA models, R5 and S1: as the best models were derivated. The statistical results of the models showed the best predictability and fitness for the fungicidal activities based on the cross- validated value ($q^2=0.714{\sim}0.823$) and non cross-validated, value ($r^2_{ncv.}=0.918{\sim}0.954$), respectively. The model R5 for fungicidal activity of RPC generated from the field fit alignment and combination of electrostatic field, H-bond acceptor field and LUMO molecular orbital field. The model S1 (or S5) for fungicidal activity of SPC generated from the atom based fit alignment and combination of steric field and HOMO molecular orbital field. The models also shows that inclusion of H-bond acceptor field (A) improved the statistical significance of the models. From the based graphical analyses of CoMSIA contribution maps, it was revealed that the novel selective character for fungicidal activities between the two fungi by modify of X-sub-stituent on the N-phenyl group and R-substituent on the S-phenyl group will be able to achivement.

An integrated elastomer substrate with a lens array and pixel elements for three-dimensional liquid crystal displays

  • Hong, Jong-Ho;Kim, Yeun-Tae;Kim, Yun-Hee;Lee, Byoung-Ho;Lee, Sin-Doo
    • Journal of Information Display
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    • v.13 no.2
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    • pp.55-59
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    • 2012
  • In this paper, a concept of an integrated elastomer substrate for a three-dimensional (3D) liquid crystal display based on the integral-imaging method is presented. The elemental lens array and columnar spacers were integrated into one of the two substrates, an elastomer substrate, through an imprinting process. The integrated elastomer substrate was capable of maintaining the uniform liquid crystal (LC) cell gap and promoting homeotropic LC alignment without any surface treatment. The monolithic approach reported herein will provide a key component for 3D displays with enhanced portability through a more than 40% weight reduction compared with the conventional integral-imaging method.

Facial Feature Extraction with Its Applications

  • Lee, Minkyu;Lee, Sangyoun
    • Journal of International Society for Simulation Surgery
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    • v.2 no.1
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    • pp.7-9
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    • 2015
  • Purpose In the many face-related application such as head pose estimation, 3D face modeling, facial appearance manipulation, the robust and fast facial feature extraction is necessary. We present the facial feature extraction method based on shape regression and feature selection for real-time facial feature extraction. Materials and Methods The facial features are initialized by statistical shape model and then the shape of facial features are deformed iteratively according to the texture pattern which is selected on the feature pool. Results We obtain fast and robust facial feature extraction result with error less than 4% and processing time less than 12 ms. The alignment error is measured by average of ratio of pixel difference to inter-ocular distance. Conclusion The accuracy and processing time of the method is enough to apply facial feature based application and can be used on the face beautification or 3D face modeling.