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A STUDY ON MAGNETIC RESONANCE IMAGING OF THE TEMPOROMANDIBULAR JOINT (악관절에 대한 자기 공명 영상의 연구)

  • Kim Hyung Sik;Kim Jae Duk
    • Journal of Korean Academy of Oral and Maxillofacial Radiology
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    • v.20 no.2
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    • pp.187-198
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    • 1990
  • Examinations of the temporomandibular joints were performed on a 1.5 Tesla magnetic resonance (MR) system. An MR surface receiver coil 3 inch in diameter was placed on plastic frame, the patient's head being placed in the frame so that the coil was pressed against the temporal region. In taking advantage of the magnetic resonance imaging that has been studied briskly till now, author obtained the images of parasagittal and paracoronal planes about the temporomandibular joint by using MPGR (Multi-Planar Gradient Recalled), GRASS (Gradient Recalled Acquisition in the Steady State), and CSMEMP (Contiguous Slice Multiple Echo, Multi-Planar), that differ from the Spin Echo pulse sequence which the previous authors used. Five subjects with no symptoms of temporomandibular joint pain and dysfunction were studied. The plane images obtained by these methods were compared with those by Spin Echo pulse sequence. The results were as follows: 1. The optimal repetition times (TR) and echo times (TE) for T.M.J. image were; a. 400 msec and 18 msec in PMGR pulse sequence. b. 40 msec and 12 msec in GRASS pulse sequence. c. 700 msec and 30 msec in CSMEMP pulse sequence. d. 500 msec and 20 msec in Spin Echo pulse sequence. 2. When the MPGR pulse sequence was using, T2-weighted image was obtained in very short time. On the image of the paracoronal plane by GRASS pulse sequence, meniscus showed the moderate signal intensity, and the meniscus and its anteromedial, posterolateral attachments were observed definitely with gray color. 4. The signal intensity of Spin Echo pulse sequence was equal to that of CSMEMP pulse sequence, but the image by CSMEMP pulse sequence showed relatively lower level in its resolution.

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Assessment of the Nature and Severity of Pain Using SF-MPQ for Cancer Patients at the National Institute of Oncology in Rabat in 2015

  • Nabila, Rouahi;Zineb, OuazzaniTouhami;Hasna, Ahyayauch;Nisrin, El Mlili;A, Filali-Maltouf;Zakaria, Belkhadir
    • Asian Pacific Journal of Cancer Prevention
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    • v.17 no.8
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    • pp.3997-4001
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    • 2016
  • Background: Cancer is a worldwide health problem and pain is among the most common and unpleasant effects affecting well-being of cancer patients. Accurate description of pain can help physicians to improve its management. Many English tools have been developed to assess pain. Onkly a limited number of these are applied in Arab countries. Our aim was to assess the quality, the nature and the severity of pain using the short McGill Pain Questionnaire (SF-MPQ) on cancer patients in the National Institute of Oncology (NIO) in Rabat, Morocco. Materials and Methods: The tool used is the SF-MPQ inspired from the Arabic version of the MPQ. The subjects were cancer patients (N=182) attending the NIO, from 24th October 2015 to 8th January 2016, aging ${\geq}18$ years old, experiencing pain and coming to have or to update their pain medication. Results: The rate of participation was 96.3%. Eight patients had difficulties to express their pain using descriptors, but could use the Visual Analogue Scale (VAS) and the body diagram. The most frequent sensory descriptors were 'Throbbing', 'Shooting', 'Hot-Burning'. The most used affective descriptor was 'Tiring-Exhausting'. The mean VAS was 6.6 (2.4). The mean score of all items was 11.9 (7.8). The patients were suffering from severe pain. The internal consistency of the form was s acceptable. Conclusions: The findings indicate that most of the patients attending the pain center of the NIO could use the descriptors of the SF-MPQ to describe their pain. They indicate the usefulness of the SF-MPQ to assess the nature and the severity of pain in cancer patients. This tool should be tested in other Moroccan and Arabic contexts associated with other tools in clinical trials.

Computational study of the hemodynamics of the patients after the Fontan procedure (Fontan 시술 이후 환자의 혈류역학적 상태에 대한 수치적 연구)

  • Shim, Eun-Bo;Ko, Hyung-Jong;Kim, Kyung-Hoon;Kamm, Roger D.
    • Proceedings of the KSME Conference
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    • 2000.11b
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    • pp.371-376
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    • 2000
  • In this study, the computational method is presented to simulate the hemodynamics of the patients after the Fontan procedure. The short-term feedback control models are implemented to assess the hemodynamic responses of the patients exposed to the stresses such as gravitational effect or hemorrhage. To construct the base line of the Fontan model, we assume an increase in venous tone, in heart rates, and in systemic resistance that are based on the clinical observations. For the verification of the present method we simulate the LBNP (lower body negative pressure) test for the normal and the Fontan model and we compare these with experimental data. Computational results show that the diastolic ABP(arterial blood pressure) increases but the systolic ABP decreases during LBNP. The increase in heart rate is due to the control system activated by the decreased mean ABP and CVP(central venous pressure). In case of the Fontan model, the increased venous tone is the reason of the diminished CVP change during LBNP. We also simulate 20% hemorrhage stress to the patient after the Fontan procedure and these results are compared with the experimental and the existing computational one. Computational results on the hemodynamics of patients after the Fontan procedure show that the mean ABP and cardiac output decrease. Heart rate and systemic resistance increase to compensate for the decrease in ABP. The sensitivity analysis according to the conduit resistance is also presented to delineate the effects of the local blood flow resistance. The cardiac output decreases according to the increase of the conduit resistance. The 50% increase in the conduit resistance causes about 3% decrease of cardiac output.

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RNA Interference-Mediated Knockdown of Astrocyte Elevated Gene-1 Inhibits Growth, Induces Apoptosis, and Increases the Chemosensitivity to 5-Fluorouracil in Renal Cancer Caki-1 Cells

  • Wang, Peng;Yin, Bo;Shan, Liping;Zhang, Hui;Cui, Jun;Zhang, Mo;Song, Yongsheng
    • Molecules and Cells
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    • v.37 no.12
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    • pp.857-864
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    • 2014
  • Astrocyte elevated gene-1 (AEG-1) is a recently discovered oncogene that has been reported to be highly expressed in various types of malignant tumors, including renal cell carcinoma. However, the precise role of AEG-1 in renal cancer cell proliferation and apoptosis has not been clarified. In this study, we transfected the renal cancer cell line Caki-1 with a plasmid expressing AEG-1 short hairpin RNA (shRNA) and obtained cell colonies with stable knockdown of AEG-1. We found that AEG-1 down-regulation inhibited cell proliferation and colony formation and arrested cell cycle progression at the sub-G1 and G0/G1 phase. Western blot analysis indicated that the expression of proliferating cell nuclear antigen (PCNA), cyclin D1 and cyclin E were significantly reduced following AEG-1 down-regulation. In addition, AEG-1 knockdown led to the appearance of apoptotic bodies in renal cancer cells, and the ratio of apoptotic cells significantly increased. Expression of the antiapoptotic factor Bcl-2 was dramatically reduced, whereas the pro-apoptotic factors Bax, caspase-3 and poly (ADPribose) polymerase (PARP) were significantly activated. Finally, AEG-1 knockdown in Caki-1 cells remarkably suppressed cell proliferation and enhanced cell apoptosis in response to 5-fluorouracil (5-FU) treatment, suggesting that AEG-1 inhibition sensitizes Caki-1 cells to 5-FU. Taken together, our data suggest that AEG-1 plays an important role in renal cancer formation and development and may be a potential target for future gene therapy for renal cell carcinoma.

Effects of Psychrotrophic Bacteria, Serratia liquefaciens and Acinetobacter genomospecies 10 on Yogurt Quality

  • Shin, Yong Kook;Oh, Nam Su;Lee, Hyun Ah;Choi, Jong-Woo;Nam, Myoung Soo
    • Food Science of Animal Resources
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    • v.34 no.4
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    • pp.543-551
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    • 2014
  • The aim of this study was to evaluate the effect of proteolytic (Serratia liquefaciens, match %: 99.39) or lipolytic (Acinetobacter genomospecies 10, match %: 99.90) psychrotrophic bacteria (bacterial counts, analysis of free fatty acids (FFA) and analysis of free amino acids) on the microbial and chemical properties (yogurt composition), and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE) of yogurt during storage. Yogurts were prepared with raw milk preinoculated with each psychrotrophic bacteria. The total solid, fat, and protein content were not affected by preinoculation, but the pH of yogurt preinoculated with psychrotrophic bacteria was higher than in control. There was a dramatic increase in short chain free fatty acids among FFA in yogurt with Acinetobacter genomospecies 10. For 14 d of cold storage condition, SCFFA was 25.3 mg/kg to 34.4 mg/kg (1.36 times increased), MCFFA was 20.4 mg/kg to 25.7 mg/kg (1.26 times increased), and LCFFA was 240.2 mg/kg to 322.8 mg/kg (1.34 times increased). Serratia liquefaciens (match %: 99.39) in yogurt caused a greater accumulation of free amino acids (FAA), especially bitter peptides such as leucine, valine, arginine, and tyrosine, but SDS-PAGE showed that the inoculation of Serratia liquefaciens did not affect the degree of casein degradation during storage. Taken together, the excessive peptides and FFA in yogurt generated from psychrotrophic bacteria could develop off-flavors that degrade the quality of commercial yogurt products.

A Study on Dan-Ryong (단령에 관한 연구)

  • Lim Jae Young
    • Journal of the Korean Society of Clothing and Textiles
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    • v.8 no.3
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    • pp.31-42
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    • 1984
  • This paper is a research on the origins and the developing process of $Dan-Ry\={o}ng$ centering on the change of its form. From the beginning of A. D era Central Asia had played the important role of a traffic route connecting China and its western adjacent world. Through this route $Dan-Ry\={o}ng$ was introduced into China (South-North Dynasty era). The form of $Dan-Ry\={o}ng$ in early period was Ban-Gum-Po (Open-collared costume that turn down the collar to the outside), and it could be worn close-collared or open-collared. From the fact that the people who wore $Dan-Ry\={o}ng$ in early period were mainly Iranian and that it was also worn by lower class like a waiting maid, it can be said that $Dan-Ry\={o}ng$ was not the costume of Han race. In early period the motif of the inside of collar was Persian style, and the people of central Asia was mostif Iranian. In short, $Dan-Ry\={o}ng$ was the costum of the people lived in the adjacent world west of China, particulary Iranians. The form of $Dan-Ry\={o}ng$ changed from Ho-Bok to Ban-Gum-Po owing to the differences in climate. In conclusion, $Dan-Ry\={o}ng$ originated in Ho-Bok ana was introduced into the world west of china by the movement of Horrse-riding Race. Then its form was changed owing to the factors like climate, natural and cultural features, and consepuently it was introduced into China by way of Centeral Asia. In China it was settled as $Dan-Ry\={o}ng$ through the ages of T'ang dynasty, Sung dynasty, Ming dynasty.

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A Study on Nutrition Intake Related to Food Habit and Family Environmental Factor of High School Girls in Seoul (서울시내 일부 여고생의 食行動 및 家族環境과 관련된 營養攝取樣相 조사연구)

  • Kim, Hyong Ran
    • Journal of Environmental Health Sciences
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    • v.12 no.2
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    • pp.49-66
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    • 1986
  • The purpose of this study was to investigate nutrition intake of high school girls related to food habit, physical status, family environmental factor. The survey of 216 high school girls, aged 15 to 17 years old in Seoul area was conducted from April, 21 to 30, 1986. Food habit and family environmental factor were researched by means of questionnaires and nutrition intake was surveyed. by recording the kinds, amounts and ingredients of foods taken by the girls for two days, and height and weight were also measured during the period. The findings are summarized as follows: 1. Mean value of height and weight of the girls were 157.6cm and 50.9kg. 2. Number of family members per household was 5.2. Mean value of father's age was 47.1 and mean value of mother's age was 43.6. 44.9% of the girls had fathers who graduated the college, 41.6% of the girls had mothers who graduated the high school and 29.2% of the girls had mothers who had the job. 3. Breakfast missing rate was high, most of the reason for breakfast missing was 'have no time to eat' and time for breakfast was short. 64.4% of the girls had meal irregularly. 4. Mean daily intake of all nutrients except vitamin A and riboflavin was higher than Recommended Dietary Allowances. Mean caloric intake was 89.8% of R.D.A.. Breakfast intake of energy and most of nutrients was less than snack. Mean meal balance score was 47.9 and mean food diversity score was 13.4. 5. Mother's education level was related to intake of protein and calcium and height. Breakfast and lunch missing and number of snack intake were related with nutrition intake.

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A Study on the Design of Single Phase Cycloconverter by Cosine Wave Crossing Control Method (코사인 점호방식에 의한 단상 싸이클로콘버터의 설계에 관한 연구)

  • 김시헌;안병원;노창주
    • Journal of Advanced Marine Engineering and Technology
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    • v.17 no.5
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    • pp.71-85
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    • 1993
  • The Cycloconverter that the author is going to treat in this paper, has strong advantages over the D.C. Link Inverter in points of chattering torque problem and natural commutation. Thus, the Cycloconverter is expected to be well applied to large and low-speed machines which require better speed control at low frequency. But the control circuit of Cycloconverter has two weak points described as follows. 1) Because of its rather complicated control circuit, it is likely to be illoperating due to unexpected noise signals, thus the higher the accuracy and reliability of the circuit is required to be, the more the circuit may cost. 2) Because the load current is not purely sinusoidal, the Cycloconverter may possibly be destroyed in case of inaccurate convert switching resulted from the difficulties in detecting the load current-zero and the current direction at the moment. In this paper, the author first of all intends to design and build a modified VVVF-type Noncirculating Current Cycloconverter to which recently proposed control methods are applied for improving the circuit simplicity, the control performance, and the system reliability. And then, experiments for observing the output waveforms of the Cycloconverter which is controlled by Singled-Board Computer using 8086 16-bit microprocesser are carried out. Finally the author concludes the result of this study as follows. 1) By replacing the conventional analog control circuits such as Reference Wave Generator, Cosine Timing Wave Generator, and Comparator with softwares, a great circuit simplicity is achieved. 2) The output of the designed Cycloconverter changes its frequency very fast without showing discontinuity of its waveform, and this waveform characteristics enables the smooth speed control of Induction Motor. 3) The design control circuit of Cycloconverter can be applied to the systems of 12 or 24 pulses because of its short processing period.

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A Study on the Formal Characteristics of Theo van Doesburg's Counter-construction - Focus on the House Projects in 1923 De Stijl Exhibition - (테오 판 두스부르흐의 반-구축적 조형특성에 관한 연구 - 1923년 데 스틸 전시회의 주택설계작품을 중심으로 -)

  • Suh, Jeong-Yeon
    • Korean Institute of Interior Design Journal
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    • v.19 no.3
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    • pp.30-37
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    • 2010
  • Dutch artist, Theo van Doesburg had shown short but strong experimental aesthetics in his works through De Stijl movement. He played a leading role for editing De Stijl magazine and performed various formative works such as painting, sculpture, and architecture. In 1923 he opened the first De Stijl exhibition cooperated with Cornelis van Eesteren. In this architecture exhibition he showed rich formal spirits of counter-construction in his major design works, that is Maison Particuliere and Maison D'artiste among three houses projects. Formal characteristics of counter-construction can be summed up under two categories, time and space. Analytical results are as follows; First, the characteristics of counter-construction related to time category include two types of two mode. One is linear aspect of time based on the viewer's movement. The other aspect is simultaneity caused by synoptical effect. These could be proved by the analysis of arrangement of color planes. Secondly, the spatial aspects of counter-construction are produced through two different ways of formal strategies. Van Doesburg arranged cubes in very irregular pattern. This treatment induces ambiguous void and creates feeling of subject's space. And, through deleting, shifting, and extending he could make dynamic spatial effect by interpenetration between in and out. This fluid space thus introduces movements of one's gaze and circulation. He denied traditional classical values which had ruled the western aesthetical discipline for centuries and believed that mankind can reach the realm of universal equilibrium by contrast and tension created by counter-construction. In this vein Theo van Doesburg was an avant-garde artist of Hegelian thoughts who adopted the dialectical method without following the formal characteristics from ancestors.

A Study on the Computational Analysis of 355nm UV Laser Multiple-Pulsed Micro Machining Considering the Strain Rate Effect (변형률 속도 효과를 고려한 355nm UV 레이저 다중 펄스 미세가공의 전산해석에 관한 연구)

  • Lee, Jung-Han;Oh, Jae-Yong;Park, Sang-Hu;Nam, Gi-Jung;Ryu, Gwang-Hyun;Shin, Suk-Hun;Shin, Bo-Sung
    • Journal of the Korean Society for Precision Engineering
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    • v.27 no.10
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    • pp.29-33
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    • 2010
  • UV laser micromachining of metallic materials has been used in microelectronic and other industries. This paper shows on experimental investigation of micromachining of copper using a 355nm UV laser with 50ns pulse duration. A finite element model with high strain rate effect is especially suggested to investigate the phenomena which are only dominated by mechanically pressure impact in disregard of thermally heat transfer. In order to consider the strain rate effect, Cowper-Symonds model was used. To analyze the dynamic deformation during a very short processing time, which is nearly about several tens nanoseconds, a commercial Finite Element Analysis (FEA) code, LS-DYNA 3D, was employed for the computational simulation of the UV laser micro machining behavior for thin copper material. From these computational results, depth of the dent (from one to six pulsed) were observed and compared with previous experimental results. This will help us to understand interaction between UV laser beam and material.