• The Journal of Korean Institute of Information Technology
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• v.15 no.12
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• pp.165-171
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• 2017

This paper proposes a method of support-generation using morphological image processing instead of geometric calculations. The geometric computational cost is dependent on the shape, but our method is independent on the shape. For obtaining the external support area for extrusion shape, we represents morphological operations between two sliced layer images and shows results of each operation stages. Internal support area is evaluated from erosion and opening operations with the sliced-layer image. In these support areas, the supporter image is generated using the designed support structures. Also, we made a DLP printer and the STL model included supporter-structure is printed by the DLP printer. We confirmed the necessity of support-generation method with the support structures individually dependent on materials by looking at the printed results.

• Asian Pacific Journal of Cancer Prevention
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• v.13 no.6
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• pp.2823-2828
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• 2012

Objective: To explore a new model of in-situ xenograft lymphangiogenesis of human colonic adenocarcinomas in nude mice. Method: On the basis of establishing subcutaneous xenograft lymphangiogenesis model of human colonic adenocarcinoms, in-situ xenografts were established through the in situ growth of the HT-29 human colonic adenocarcinoma cell line in nude mice. The numbers of lymphangiogenic microvessels, the expression of lymphatic endothelial cell markers lymphatic vessel endothelial hyaloronic acid receptor-1 (LYVE-1), D2-40 and the lymphatic endothelial growth factors vascular endothelial growth factor-C (VEGF-C), -D (VEGF-D) and receptor-3 (VEGFR-3) were compared by immunohistochemical staining, Western bolt and quantitative RT-PCR in xenograft in-situ models. Results: Some microlymphatics with thin walls, large and irregular or collapsed cavities and increased LMVD, with strong positive of LYVE-1, D2-40 in immunohistochemistry, were observed, identical with the morphological characteristics of lymphatic vessels and capillaries. Expression of LYVE-1 and D2-40 proteins and mRNAs were significantly higher in xenograpfts in-situ than in the negative control group(both P<0.01). Moreover, the expression of VEGF-C, VEGF-D and VEGFR-3 proteins and mRNAs were significantly higher in xenografts in-situ (both P<0.01), in conformity with the signal regulation of the VEGF-C,-D/VEGFR-3 axis of tumor lymphangiogenesis. Conclusions: In-situ xenografts of a human colonic adenocarcinoma cell line demonstrate tumor lymphangiogenesis. This novel in-situ animal model should be useful for further studying mechanisms of lymph node metastasis, drug intervention and anti-metastasis therapy in colorectal cancer.

• Journal of the Korean Society of Manufacturing Process Engineers
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• v.17 no.5
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• pp.117-122
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• 2018

3D printing technology and its applications have grown rapidly in academia and industry. We consider a 3D printing system designed for the selective laser sintering (SLS) method, which is one of the powder bed fusion (PBF) techniques to build up the final product by layering sintered powder slices. Thermal distortion of printing products is a critical challenge in 3D printing. This study investigates temperature-dependent conformational behaviors of 3D printed samples of sintered poly-ether-ether-ketone (PEEK) powders using molecular dynamics simulations. The wear and chemical resistance properties of PEEK are understood, as it is a well-known biocompatible material used for implants. However, studies on physical phenomena at nanoscale in PEEK are rarely published in public. We simulate dissipative particle dynamics to elucidate how a cavity regime forms in PEEK at different system temperatures. We demonstrate how PEEK structures deform subject to the system temperature distribution.

• Reproductive and Developmental Biology
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• v.35 no.2
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• pp.143-149
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• 2011

Arthritis is a common disease in aged people, and is clinically divided into rheumatoid arthritis (RA) and osteoarthritis (OA). Although common symptoms such as pain are present, the underlying pathological mechanisms are slightly different. Therefore, the objectives of the present study were to compare joint damage induced by RA and OA by analyzing the major morphological and molecular differences, and to propose a suitable therapeutic intervention based on the pathophysiological conditions of bones and joints. For the RA animal model, 8-week-old DBA1/J mice were immunized with bovine type II collagen emulsified in complete Freund's adjuvant (CFA). Normal C57BL/6 mice (over 2 years of age) were used for OA. The clinical arthritis score was calculated using a subjective scoring system, and paw thicknesses were measured using calipers. The serum TNF ${\alpha}$ level was analyzed using an ELISA kit. Micro-CT was used to identify pathological characteristics and morphological changes. In collagen-induced RA mice, there were increased ankle joint volumes and clinical scores (p<0.01). The concentration of TNF ${\alpha}$ was significantly increased from 3 to 7 weeks after immunization. Micro-CT images showed trabecular bone destruction, pannus formation, and subchondral region destruction in RA mice. OA among aged mice showed narrowed joint spaces and breakdown of articular cartilage. This study suggests that a careful therapeutic intervention between RA and OA is required, and it should be based on morphological alteration of bone and joint.

• Journal of KIISE:Computer Systems and Theory
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• v.32 no.10
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• pp.520-529
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• 2005

A feature-based 3D modeling algorithm is presented in this paper. Since conventional methods use depth-based techniques, they need much time for the image matching to extract depth information. Even feature-based methods have less computation load than that of depth-based ones, the calculation of modeling error about whole pixels within a triangle is needed in feature-based algorithms. It also increase the computation time. Therefore, the proposed algorithm consists of three phases, which are an initial 3D model generation, model evaluation, and model refinement phases, in order to acquire an efficient 3D model. Intensity gradients and incremental Delaunay triangulation are used in the Initial model generation. In this phase, a morphological edge operator is adopted for a fast edge filtering, and the incremental Delaunay triangulation is modified to decrease the computation time by avoiding the calculation errors of whole pixels and selecting a vertex at the near of the centroid within the previous triangle. After the model generation, sparse vertices are matched, then the faces are evaluated with the size, approximation error, and disparity fluctuation of the face in evaluation stage. Thereafter, the faces which have a large error are selectively refined into smaller faces. Experimental results showed that the proposed algorithm could acquire an adaptive model with less modeling errors for both smooth and abrupt areas and could remarkably reduce the model acquisition time.

• Journal of the Korean Society of Clothing and Textiles
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• v.31 no.3 s.162
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• pp.463-474
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• 2007

With rapid expansion in e-retailing of apparel business, personalized fitting model service shows the possibility as the differentiated marketing strategy in cyber shopping. According as necessity of personalized fitting model construction rises, it is tried personalized fitting model creation in several fields such as computer engineering, mechanical engineering, information engineering. But, because existent study was concentrated only on human body modeling, it does not reflect average morphological characteristics of human body properly. In this study, we wish to examine if morphing is fit for expressing characteristic of average human body shape and suggest desirable morphing. We used 3-D scan data of 254 Korean middle aged men collected by Size Korea 2004. The result of this study are as follows: Lower body types were categorized by height hip girth and lower drop(hip girth-navel girth) which were main factors of lower body shape. Then each factor was divided into 3 groups respectively, 30% in the middle, over 30%, under 30%. In 27 groups, the group which belonged to 30% in the middle of height, 30% in the middle of hip girth, 30% in the middle of lower drop was selected as a representative group. We tested geometrical figure by differ volume, tilt, position of point. And we created a representative type of men's lower bodies by morphing the representative group and analyzed it's horizontal, vertical sections. A representative type which was created by morphing reflected a real body and changed realistically at the part of hip, crotch, calf muscle and so on. A cross sections of a representative type were similar to average cross sections of the representative group in size and shape. So it was proved that morphing was successful.

• Journal of The Korean Astronomical Society
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• v.17 no.2
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• pp.69-103
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• 1984

Five different calibrations of metal abundances of globular clusters are examined and these are compared with metallicity ranking parameters such as $(Sp)_c$, . Q39 and IR-indices. Except for the calibration $[Fe/H]_H$ by the high dispersion echelle analysis. the other calibration scales are correlated with the morphological parameters of red giant branch. In the $[Fe/H]_H$-scale. the clusters later than ${\sim}F8$ have nearly a constant metal abundance. $[Fe/H]_H{\simeq}-1.05$, regradless of morphological characteristics of horizontal branch and red giant branch. By the two fundamental calibration scales of $[Fe/H]_L$ (derived by the low dispersion analysis) and $[Fe/H]_{{\Delta}s}$ (derived by the spectral analysis of RR Lyrae stars). the globular clusters are divided into the halo clusters with [Fe/H]<-1.0 and the disk clusters confined within the galactocentric distance ${\tau}_G=10\;kpc$ and galactic plane distance |z|=3 kpc. In this case the abundance gradient is given by d[Fe/H]/$dr_G{\approx}-0.05\;kpc^{-1}$ and d[Fe/H]/$d|z|{\simeq}-0.08\;kpc^{-1}$ within ${\tau}_G=20\;kpc$ and |z|=10 kpc, respectively. According to these characteristics of the spatial distribution of globular clusters. the chemical evolution of the galactic globular clusters can be accounted for by the two-zone (disk-halo) slow collapse model when the $[Fe/H]_L$-or $[Fe/H]_{{\Delta}s}$-scale is applied. In the case of $[Fe/H]_H$-scale, the one-zone fast collapse model is preferred for the evolution of globular clusters.