• Title/Summary/Keyword: 3D FR

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IMGT Unique Numbering for Standardized Contact Analysis of Immunoglobulin/antigen and T cell receptor/peptide/MHC Complexes

  • Kaas, Quentin;Chiche, Laurent;Lefrane, Marie-Paule
    • Proceedings of the Korean Society for Bioinformatics Conference
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    • 2005.09a
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    • pp.209-214
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    • 2005
  • Immunoglobulins (IG) , T cell receptors (TR) and major histocompatibility complex (MHC) are major components of the immune system. Their experimentally determined three-dimensional (3D) structures are numerous and their retrieval and comparison is problematic. IMGT, the international ImMunoGeneTics information system$^{\circledR}$(http://imgt.cines.fr), has devised controlled vocabulary and annotation rules for the sequences and 3D structures of the IG TR and MHC. Annotated data from IMGT/3D sructure-DB, the IMGT 3D structure database, are used in this paper to compare 3D structure of the domains and receptor, and to characterize IG/antigen, peptide/MHC and TR/peptide/MHC interfaces. The analysis includes angle measures to assess receptor flexibility, structural superimposition and contact analysis. Up-to-date data and analysis results are available at the IMGT Web site, http://imgt.cines.fr.

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Design and Fabrication of Low Frequency Driven Energy Harvester Using Electromagnetic Conversion

  • Lee, Byung-Chul;Chung, Gwiy-Sang
    • Transactions on Electrical and Electronic Materials
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    • v.14 no.3
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    • pp.143-147
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    • 2013
  • This paper describes a low frequency driven electromagnetic energy harvester (EMEH) which consists of a thin flame resistant (FR-4) planar spring, NdFeB permanent magnets, and a copper coil. The FR-4 spring was fabricated using a desk computer numerical control (CNC) 3D modeling machine. Mathematical modeling and ANSYS finite element analysis (FEA) were used totheoretically investigate the mechanical properties of the spring mass system. The proposed EMEH generates a maximum power of 65.33 ${\mu}W$ at a resonance frequency of 8 Hz with an acceleration of 0.2 g (1 g = 9.8 $m/s^2$) and a superior normalized power density (NPD) of 77 ${\mu}W/cm^3{\cdot}g^2$.

Design and fabrication of the X-band microwave amplifier for Electronic Radar Reflector (전자식 레이더 반사기를 위한 X-band 마이크로웨이브 증폭기 설계 및 구현)

  • 정종혁;양규식
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.2 no.3
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    • pp.275-282
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    • 1998
  • In this paper, we designed and fabricated 5-stage microwave solid state power amplifier using balanced amplifier scheme for X-band electronic radar reflector. The used substrate is FR4 and the used active devices are FHX35LC, FLK012WF and FLK022WG. The circuit design and optimization had been carried out through the microwave CAD program CNL2 The measured values show 46dB in gain, input return loss -14.2dB, output return loss -16.6dB and IM3 is 32dBc at designed bandwidth. The measured results are almost agreed with the simulated values.

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Design of 24-GHz 1Tx 2Rx FMCW Transceiver (24 GHz 1Tx 2Rx FMCW 송수신기 설계)

  • Kim, Tae-Hyun;Kwon, Oh-Yun;Kim, Jun-Seong;Park, Jae-Hyun;Kim, Byung-Sung
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.29 no.10
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    • pp.758-765
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    • 2018
  • This paper presents a 24-GHz frequency-modulated continuous wave(FMCW) radar transceiver with two Rx and one Tx channels in 65-nm complementary metal-oxide-semiconductor(CMOS) process and implemented it on a radar system using the developed transceiver chip. The transceiver chip includes a $14{\times}$ frequency multiplier, low-noise amplifier, down-conversion mixer, and power amplifier(PA). The transmitter achieves >10 dBm output power from 23.8 to 24.36 GHz and the phase noise is -97.3 GHz/Hz at a 1-MHz offset. The receiver achieves 25.2 dB conversion gain and output $P_{1dB}$ of -31.7 dBm. The transceiver consumes 295 mW of power and occupies an area of $1.63{\times}1.6mm^2$. The radar system is fabricated on a low-loss Duroid printed circuit board(PCB) stacked on the low-cost FR4 PCBs. The chip and antenna are placed on the Duroid PCB with interconnects and bias, gain blocks and FMCW signal-generating circuitry are mounted on the FR4 PCB. The transmit antenna is a $4{\times}4$ patch array with 14.76 dBi gain and receiving antennas are two $4{\times}2$ patch antennas with a gain of 11.77 dBi. The operation of the radar is evaluated and confirmed by detecting the range and azimuthal angle of the corner reflectors.

A Small Broadband Antenna for Wibro/WLAN/Mobile WiMAX (Wibro/WLAN/Mobile WiMAX용 소형 광대역 안테나)

  • Ko, Jeong-Ho;Choi, Ik-Guen
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.22 no.5
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    • pp.568-575
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    • 2011
  • In this paper, we propose a small broadband antenna for mobile device. The proposed antenna consists of a printed rectangular monopole antenna and a parastic element connected to ground using narrow meander line and it is designed on a FR-4 substrate that has a thickness of 0.8 mm and a dielectric constant of 4.4. The FR-4 substrate's size is 50 mm${\times}$90 mm comparable to the real mobile device. The fabricated antenna's size is 12.5 mm${\times}$10.5 mm${\times}$0.8 mm and the measurement shows -10 dB return loss bandwidth of 2,200~6,000 MHz and gains of 2.86~4.01 dBi. Accordingly, the proposed antenna can support mobile device for WiBro(2,300~2,380 MHz), WLAN(IEEE 802.11b/g/n: 2,400~2,480 MHz, IEEE 802.11a: 5,150~5,825 MHz), and mobile WiMAX(IEEE 802.16e : 2,500~2,690 MHz, 3,400~3,600 MHz) service bands.

Study on the Array type antenna of 2×2 (2×2 배열 구조 안테나 특성 연구)

  • Park, Yong-Wook
    • The Journal of the Korea institute of electronic communication sciences
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    • v.12 no.4
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    • pp.549-554
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    • 2017
  • In this paper, we studied the design and fabrication of $2{\times}2$ microstrip array antenna at around 5 GHz band.. To improve of frequency properties of antenna, feed microstrip patch antenna was simulated by HFSS(High Frequency Structure Simulator). A $2{\times}2$ array antenna was designed and fabricated by photolithograph on an FR4 substrate (dielectric constant of 4.4 and thickness of 1.6 mm). The fabricated $2{\times}2$ array antenna showed a center frequency, the minimum return loss and bandwidth were 5.3 GHz, -24dB, and 390MHz, respectively.

A flavonoid clycoside from the leaves of polygonum sachalinense (II)

  • Kang, Sam-Sik;Woo, Won-Sick
    • Archives of Pharmacal Research
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    • v.5 no.1
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    • pp.13-15
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    • 1982
  • Quercetin-3-O-${\beta}$-D glucofuranoside, mp 243-$6^{\circ}$, was isolate dfrom leaves of Polygonum sachalinense Fr. Schm and characterized on the basis of its spectral data. This is the second report of its occurrence in nature.

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Comparison of Nutrient Replenishing Effect under Different Mixing Methods in a Closed-loop Soilless Culture using Solar Radiation-based Irrigation (적산 일사 제어법으로 관수하는 순환식 수경재배에서 배액 혼합 방식에 의한 재사용 양액 내 양분 조정효과 비교)

  • Ahn, Tae-In;Shin, Jong-Hwa;Noh, Eun-Hee;Son, Jung-Eek
    • Journal of Bio-Environment Control
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    • v.20 no.4
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    • pp.247-252
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    • 2011
  • Electrical conductivity, drainage, and irrigation amount of nutrient solution are important factors for determination of the mixing ratio of fresh and reused nutrient solutions in closed-loop soilless culture. Generally a fixed mixing ratio is applied in commercial scale greenhouses using solar radiation-based irrigation system. Although it ensures continuous supply of fresh nutrient solution in the mixing process, occasional discharge of the drainage is inevitably required. This study was conducted to compare the nutrient replenishing effect under different mixing processes and to investigate appropriate mixing process. For this experiment, a fixed mixing ratio (FR), modifiable mixing ratio (MR), and open-loop (OP) as control were applied. Mixing ratio was determined by a set value of EC for dilution of collected drainage in FR and the set values of 1.0 and $2.0dS{\cdot}m^{-1}$ were used as treatments (FR 1.0 and FR 2.0), respectively. In MR, mixing ratio was determined based on EC and volume of drainage within irrigation volume per event. The volume of drainage stored in the drainage tank tended to increase in FR 1.0. Although such trend was not observed in FR 2.0 and MR, the volume of drainage stored in MR was lower than that in FR 2.0. The ion balance of $Mg^{2+}:K^+:Ca^{2+}$ or $SO^{2-}_4:NO^-_3:PO^{3-}_4$ in the drainage and reused nutrient solution changed within a narrow range regardless of treatment.

Miniaturization of Circularly Polarized Microstrip Antenna for RFID Portable Reader at 900 MHz Band (900 MHz대 RFID 휴대 리더용 원편파 안테나 소형화)

  • Kang, Min-Sik;Choi, Ik-Guen
    • The Journal of Korean Institute of Electromagnetic Engineering and Science
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    • v.19 no.4
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    • pp.411-417
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    • 2008
  • This paper presents the miniaturization of circularly polarized microstrip patch antenna for UHF-band RFID portable reader. The proposed antenna has a group of four I-slots on a conventional corner-truncated square microstrip patch and it is shown that the antenna size is reduced compared to the antenna without I-slots. A 76 mm by 76 mm small antenna with four I-slots is fabricated with 6.4 mm thick FR4 substrate and its 10 dB return loss bandwidth, the gain and the axial ratio are measured to be $938{\sim}975\;MHz$, $-0.88{\sim}-2\;dBi$, and $3.27{\sim}13.21\;dB$ within the 10 dB return loss bandwidth, respectively.

The Immuno-Modulatory and Antitumor Effects of Crude Polysaccharides Extracted from Daedaleopsis tricolor (삼색도장버섯(Daedaleopsis tricolor)에서 추출한 조다당류의 면역 활성 및 항암 효과)

  • Shim, Sung-Mi;Im, Kyung-Hoan;Kim, Jung-Wan;Lee, U-Youn;Kim, Ha-Won;Lee, Min-Woong;Lee, Tae-Soo
    • The Korean Journal of Mycology
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    • v.31 no.3
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    • pp.161-167
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    • 2003
  • Neutral salt soluble [0.9% NaCl (Fr. NaCl)], hot water soluble (Fr. HW) and methanol soluble (Fr. MeOH) materials were extracted from Daedaleopsis tricolor. In vitro cytotoxicity tests, Fr. HW was not cytotoxic against cancer cell lines such as Sarcoma 180, HepG2 and HT-29 at the concentration of $0{\sim}2,000\;{\mu}g/ml$, while Fr. NaCl and Fr. MeOH were cytotoxic to the cell lines. Intraperitoneal injection with Fr. NaCl showed antitumor effect with life prolongation of 77.4% in mice inoculated with Sarcoma 180. Fr. NnCl and Fr. HW improved proliferation of spleen cells and the immunopotentiation activity of B lymphocyte by increasing spleen cells and the alkaline phosphatase activity by $1.7{\sim}2.4\;and\;2.2{\sim}8.7$ folds, respectively. Fr, NaCl generated $90\;{\mu}M$ of nitric oxide (NO) when cultured with RAW 264.7 at the concentration of $50\;{\mu}g/ml$, while lipopolysaccharide, a positive control, produced $79{\mu}M$. Intraperitoneal injection with Fr. NaCl (50 mg/kg body weight) increased the numbers of peritoneal exudate cells and circulating leukocytes by 10 folds and two folds, respectively, than in the control group. The antitumor effect of D, tricolor was likely due to immunopotentiation activity.