• Radiation Oncology Journal
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• v.20 no.4
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• pp.375-380
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• 2002

Purpose : To develop a practical film dosimetry system for routine Quality Assurance (QA). Materials and Methods :An One Click Film (OCF) Dosimetry system was designed to perform swift routine QA with functions including automatic fog value elimination, angle adjustment, automatic symmetry calculation, and realtime profile generation with the ability to display realtime three-dimensional dose distributions. Results : The most frequently used functions for routine QA, such as the elimination of the fog value, conversion into an H&D curve, symmetry, and isodose distribution, can be achieved with only one click. Conclusion : Reliable results were achieved with the OCF dosimetry with simpler steps than other commercially available film dosimetry systems for routine QA. More research on the refined user interface will make this system be clinically useful.

• Journal of the Korean Geotechnical Society
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• v.30 no.3
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• pp.29-46
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• 2014

For circular rigid footings with a rough base on sand, combined vertical - horizontal loading capacity was studied by three-dimensional numerical modelling. A numerical model was implemented to simulate the swipe loading and the probe loading methods and an interpretation procedure was devised in order to eliminate the numerical error from the restricted mesh density. Using the Mohr-Coulomb plasticity model, the effect of friction angle was studied under the associated flow-rule condition. The swipe loading method, which is efficient in that the interaction diagram can be drawn with smaller number of analyses, was confirmed to give similar results with the probe loading method, which follows closely the load-paths applied to real structures. For circular footings with a rough base, the interaction diagram for combined vertical (V) - horizontal (H) loading and the inclination factor were barely affected by the friction angle. It was found that the inclination factors for strip and rectangular footings are applicable to circular footings. For high H/V ratios, the results by numerical modelling of this study were smaller than the results of previous studies. Discussions are made on the factors affecting the numerical results and the areas for further researches.

• Bulletin of the Korean Chemical Society
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• v.34 no.8
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• pp.2419-2424
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• 2013

Guanosine-5'-diphosphate 3'-diphosphate (ppGpp) serves as alarmone in bacterial stringent responses. In this study, an affinity column was constructed by immobilizing ppGpp to NHS-Sepharose for isolating ppGpp-binding proteins. A novel ppGpp-binding protein, YjgA, was isolated and characterized by MALDI-TOF MS (matrix-assisted laser desorption ionization-time-of-flight mass spectrometry) coupled with two-dimensional gel electrophoresis. YjgA and truncated forms of YjgA were cloned and over-expressed in BL21 (DE3). The binding affinity of YjgA to ppGpp was determined by equilibrium dialysis. The interaction of YjgA with ppGpp was very specific, considering that the dissociation constant of YjgA with ppGpp was measured as $5.2{\pm}2.0{\mu}M$, while the affinities to GTP and GDP were about 60 and 30 times weaker than ppGpp. Expression of yjgA gene in Escherichia coli K-12 MG1655 was examined by reverse transcription polymerase chain reaction (RT-PCR). RT-PCR results revealed that yjgA was expressed from early to late stationary phase. The yjgA deletion mutant exhibited decreased cell number at stationary phase compared to parent strain and the over-expression of YjgA increased the cell number. These results suggested that YjgA might stimulate cell division under stationary phase. In most prokaryotic genome, about half of the protein candidates are hypothetical, that are expected to be expressed but there is no experimental report on their functions. The approach utilized in this study may serve as an effective mean to probe the functions of hypothetical proteins.

• Journal of Cardiovascular Imaging
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• v.31 no.1
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• pp.18-23
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• 2023

BACKGROUND: Three-dimensional (3D) transesophageal echocardiogram (TEE) is the gold standard for the diagnosis of degenerative mitral regurgitation (dMR) and preoperative planning for transcatheter mitral valve repair (TMVr). TEE is an invasive modality requiring anesthesia and esophageal intubation. The severe acute respiratory syndrome coronavirus 2 pandemic has limited the number of elective invasive procedures. Multi-detector computed tomographic angiography (MDCT) provides high-resolution images and 3D reconstructions to assess complex mitral anatomy. We hypothesized that MDCT would reveal similar information to TEE relevant to TMVr, thus deferring the need for a preoperative TEE in certain situations like during a pandemic. METHODS: We retrospectively analyzed data on patients who underwent or were evaluated for TMVr for dMR with preoperative MDCT and TEE between 2017 and 2019. Two TEE and 2 MDCT readers, blinded to patient outcome, analyzed: leaflet pathology (flail, degenerative, mixed), leaflet location, mitral valve area (MVA), flail width/gap, anterior-posterior (AP) and commissural diameters, posterior leaflet length, leaflet thickness, presence of mitral valve cleft and degree of mitral annular calcification (MAC). RESULTS: A total of 22 (out of 87) patients had preoperative MDCT. MDCT correctly identified the leaflet pathology in 77% (17/22), flail leaflet in 91% (10/11), MAC degree in 91% (10/11) and the dysfunctional leaflet location in 95% (21/22) of patients. There were no differences in the measurements for MVA, flail width, commissural or AP diameter, posterior leaflet length, and leaflet thickness. MDCT overestimated the measurements of flail gap. CONCLUSIONS: For preoperative TMVr planning, MDCT provided similar measurements to TEE in our study.

• Journal of Korean Society of Transportation
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• v.23 no.7 s.85
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• pp.159-163
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• 2005

The propriety between suppliers and demanders in geometric design is very important. Although the final purpose of constructing roads is to concern about the driver s comfort, unfortunately, it has not been considered so far. We've considered the regularity and quickness in considering driver's comfort but there should be considered the safety for the accident as well. If drivers are appeared to be more speeding than designer's intention, there will be needed some supplements to increase the safety rate for the roads. Even if both an upward and downward section are supposed to exist at the same time for solid geometry of the roads like this, it is true that the recent design for the 3-D solid geometry section has been done as flat 2-D and the minimum plane curve radius and the maximum cant have been decided just by calculating without considering operating speed between an upward and downward section at the same point. In this investigation, thus, I'd like to calculate the safety of the cant by considering the speed features of the solid geometry for the first lane of four lane rural roads. To begin with, we investigated the driving speed of the car, which is not been influenced by a preceding car to analyze the influence of the geometrical structure by using Nc-97. Secondly, we statistically analyzed the driving features of the solid geometry after comparing the 6 sections, that is, measuring the driving speed feature at 12 points and combining the influence of the vertical geometry and plane geometry to the driving speed of the plane curve which was researched before. Finally, we estimated the value of cant which considers the driving speed not by using it which has applied uniformly without considering it properly, though there were some differences between a designed speed and driving speed through the result of the basic statistical analysis but by introducing the new safety rate rule, a notion of ${\alpha}$. As a result of the research, we could see the driving features of the car and suggest the safety rate which considers these. For considering the maximum cant, if we apply the safety rate, the result of this experiment, which considers 3-D solid geometry, there'll be the improvement of the driver's safety for designing roads. In addition, after collecting and analyzing the data for the road sections which have various geometrical structures by expanding this experiment it is considered that there should be developed the models which considers 3-D solid geometry.

• Journal of the Korean Society for Marine Environment & Energy
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• v.3 no.3
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• pp.3-12
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• 2000

The field surveys and the measurements of seawater temperatures were conducted every month from 1997 to 1999, and the distributions of seawater temperature were simulated and reproduced by a three dimensional hydrodynamic numerical model over the southern waters of Cheju island. In order to estimate the marine environmental capacity for the reception of the heat loads of cooling water discharged from Hwasoon Thermal Power Plant(HTPP) in the study area, the simulations for predicting the situation of unfavorable environment in which marine organisms might not be satisfied with change in seawater temperature were peformed using a three dimensional hydrodynamic numerical model by controlling quantitatively the heat loads of cooling water from HTPP Currently, HTPP discharges cooling water of 35.9℃ into the sea as much as 112,800m³/day in summer. As the results of simulations, the more the heat loads from the power plant increase, the more increase the seawater temperatures around the water areas adjacent to the power plant. In case the heat loads of cooling water from HTPP become about 5 times as high as the present loads, seawater temperatures at near-shore waters adjacent to HTPP appear to be increased to the extent of 0.5℃ above the existing seawater temperature in summer. The marine environmental capacity for the reception of thermal discharge from HTPP is estimated to be about 530×10/sup 6/kcal/day which is equivalent to the increase of a factor of 2 in the temperature of cooling water without any change in the discharge rate of cooling water or which is equivalent to the increase of a factor of 4.6 in the discharge rate of cooling water without any change in the temperature of cooling water. Comparing the case of the increase in the discharge rate of cooling water with the case of the increase in the temperature of cooling water on the basis of the same heat loads of 530×10/sup 6/kal/day, the former case is expected to increase seawater temperature a little higher and to extend the area affected by heat loads a little broader.

• Proceedings of the Korean Society of Surveying, Geodesy, Photogrammetry, and Cartography Conference
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• 2006.04a
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• pp.425-429
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• 2006

본 연구는 VGIS(Virtual Geographic Information System)을 이용, 환경친화적인 도로건설을 위해 실제 좌표를 사용하므로 3차원 도로의 선형과 구조물을 설계하였다. 그리고 시공 중에 발생 할 수 있는 민원문제 및 설계변경 시 효율적인 의사결정 할 수 있도록 하였다. 대상지역은 전라남도 장흥군의 최대 역점사업인 관광을 테마로 한 정남진 가는 길을 컨셉으로 한 '가고 싶은 길', '보고싶은 다리', 기억하고픈 터널'을 주제로 설계하였으며 명실공히 남도의 새로운 관광명소가 될 자연관광도로가 될 것으로 기대된다. 기존의 3차원 설계에서는 평면적인 선형과 구조물의 형상을 이해하는데 상당한 시간이 소요되었지만, 구조물을 3차원으로 설계함으로써, 비전문가라도 구조물을 쉽게 파악 할 수 있었다. 그리고 3차원 설계는 기존 구조물과 신설될 구조물 사이에 공사 중 발생할 수 있는 환경 및 민원문제를 사전에 파악할 수 있었다. 또한, 실제와 같이 구현된 도로와 구조물의 시뮬레이션을 통하여 기존의 각종 의사 결정에 있어 보다 시각적 효과를 증진시켜 효율적인 의사결정을 가능하게 하였다. 본 연구에서는 실제 평면 설계에 쓰이는 좌표값을 3차원설계에 적용하였다. 도로 노선 및 경관분석에 많은 도움이 될 것으로 보이며 VGIS를 이용하므로 도시계획, 식물, 토양. 수로 또는 도로형태, 홍수계획 등 많은 일들이 평가에 사용된다. 여기서는 구조물 3차원 설계에 관한 기초적인 연구를 시행하였으며, 3차원설계를 통해 의사결정시 효율적인 판단을 할 수 있었고, 환경 친화적 시공 및 설계에 대한 연구가 이루어져야 될 것으로 판단된다.안전관리를 위해 채석장에 안전표지판을 설치하여야 하며, 실내가공 작업장의 자동이동시스템을 작업별로 채색하여 식별을 용이하게 하여야 하겠다. 또한 이 연구 결과를 영세사업장의 산업간호프로그램인 'Clean 3D'사업에서 적용하여 우리나라 채석사업장 근로자 건강관리를 발전시켜야 하겠다. 확장기 혈압에서 RZS와 DAD의 일치도와 평균을 중심으로 더 넓게 퍼져있어 낮은 일치도를 보였으며 또 DAD와 RMS의 혈압치는 숫자 선호도를 볼 수 있는데 특히 RMS는 더 뚜렷하게 나타났는데 확장기 혈압의 최빈치(30.6)는 100mmHg이었다. 혈압치들이 가장 가까이 "0"점으로 치우쳐져 있었다. RZS의 Central tendency는 DAD와 RMS보다 뚜렷하였다. 결론적으로 RZS는 이 연구목적으로 가장 적절함을 보여준다.청소년들의 학교급식에 대한 만족도를 높이기 위해서 다음과 같은 제언을 하고자 한다. 먼저, 학교급식에 대한 식단 작성 시 학생들이 학교에서 제공되기 원하는 식단에 대한 의견을 받고 그 의견에 대한 결과를 게시하여 학생들이 제공되기 원하는 식단을 급식 시 제공하여 학생들이 식단선택에 동참할 수 있는 기회를 주는 것이 바람직하겠다. 또한 영양사는 학급의 반대표와의 정기적인 모임을 가짐으로서 학생들의 불만사항 및 개선 요구사항에대해 서로 의견을 교환하여 설문지조사가 아닌 직접적인 대화를 하여 문제점을 파악하고자 하는 적극적인 자세가 필요하겠다. 특히 아침식사의 결식 빈도가 높았고 이는 급식성과에 부정적인 영향을 줄 뿐 아니라 학교에서 제공하는 음식의 섭취정도에도 영향을 주고 있으므로 학생들에게 학부모와 전담교사 및 학교영양사는 학생들

• Journal of the Korean Association of Geographic Information Studies
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• v.9 no.3
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• pp.82-92
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• 2006

As beaches throughout Korea have suffered great losses of sand due to artificial developments and meteorological phenomena, particularly typhoons, it is necessary to monitor beaches that are prone to erosion continuously, establish and enforce a comprehensive plan to attack coastal erosion with the object of the long-term management. However, debates and temporary measures, not based on accurate coastal zone surveys and analyses, have been established up to now. Therefore, with Haeundae sand beach as a case study, we proposed methods to collect accurate spatial data of the coastline and the sand beach through GPS survey. And we detected and analyzed topographic changes resulting from Typhoon Nabi quantitatively and qualitatively, by using GIS technique. Results showed a mean elevation of 1.95 m, a total area of 53,441 $m^2$, and a total volume of 104,639 $m^3$ after Typhoon Nabi. Mean elevation rose 0.06 m between the pre- and the post-typhoon surveys by a protective shore wall. However, strong winds and north-northeast surges brought by the typhoon caused erosion of the area and the volume, by 3,096 $m^2$ and 2,320 $m^3$. Accurate spatial databases of coastal zones based on integrated GPS GIS techniques and quantitative and qualitative analyses of topographical changes will help Korea develop systematic and effective countermeasures against coastal erosion.

• Journal of the Korean Geotechnical Society
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• v.35 no.3
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• pp.17-24
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• 2019

The purpose of this study is to understand the characteristics of bearing capacity of shallow foundation on the grounds. We made a comparative study of existing bearing capacity theory, based on the three-dimensional finite element analysis with a variety of conditions such as ground condition, foundation scale and foundation shape. In the finite element analysis, the ultimate bearing capacity showed a gradual convergence in the form of exponential function or logarithm function according to the foundation scale. Although the shear strength increased, the bearing capacity tended not to increase but change linearly. In the results of comparative study of existing bearing capacity theory, bearing capacity ratio ($q_{u(FEA)}/q_{u(theory)}$) of pure sand has the outcome closest to those of the Terzaghi method. Pure clay turned out to be about 0.4~0.6 while normal soil was changed in a range of 0.3~1.3. As shear strength is increased, the results turned out to be less than 1.0. Bearing capacity ratio ($q_u/q_{u(1.0)}$), normalized at 1.0m bearing capacity, was about 35%, 15% and 5% of theoretical formula under the condition of ${\phi}=25^{\circ}$, $30^{\circ}$ and $35^{\circ}$ of pure sand; no scale effect was found with pure clay and the normal soil with lower soil strength level showed less than 10% of the theoretical formula of pure sand. Bearing capacity ratio of each case, in accordance with, the shear strength increase, was largely influenced by the internal friction angle. Shape factor of bearing capacity ratios classified by foundation shapes have different results according to the shapes; the shape factor of circular foundation is 1.50, square foundation is 1.30, rectangular and continuous foundations are 1.1~1.0.

• The Korean Journal of Pesticide Science
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• v.9 no.1
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• pp.26-34
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• 2005

3D-QSAR studies for the fungicidal activities against resistance phytophthora blight (RPC; 95CC7303) and sensitive phytophthora blight (Phytopthora capsici) (SPC; 95CC7105) by a series of new 2-alkoxyphenyl-3-phenylthioisoindoline-1-one derivatives (A & B) were studieded using comparative molecular similarity indices analyses (CoMSIA) methodology. From the based on the results, the two CoMSIA models, R5 and S1: as the best models were derivated. The statistical results of the models showed the best predictability and fitness for the fungicidal activities based on the cross- validated value ($q^2=0.714{\sim}0.823$) and non cross-validated, value ($r^2_{ncv.}=0.918{\sim}0.954$), respectively. The model R5 for fungicidal activity of RPC generated from the field fit alignment and combination of electrostatic field, H-bond acceptor field and LUMO molecular orbital field. The model S1 (or S5) for fungicidal activity of SPC generated from the atom based fit alignment and combination of steric field and HOMO molecular orbital field. The models also shows that inclusion of H-bond acceptor field (A) improved the statistical significance of the models. From the based graphical analyses of CoMSIA contribution maps, it was revealed that the novel selective character for fungicidal activities between the two fungi by modify of X-sub-stituent on the N-phenyl group and R-substituent on the S-phenyl group will be able to achivement.