[ $\underline{Purpose}$ ]: To evaluate the incidences and potential predictive factors for symptomatic radiation pneumonitis (SRP) and radiographic pulmonary toxicity (RPT) following adjuvant radiotherapy (RT) for patients with breast cancer. A particular focus was made to correlate RPT with the dose volume histogram (DVH) parameters based on three-dimensional RT planning (3D-RTP) data. $\underline{Materials\;and\;Methods}$: From September 2003 through February 2006, 171 patients with breast cancer were treated with adjuvant RT following breast surgery. A radiation dose of 50.4 Gy was delivered with tangential photon fields on the whole breast or chest wall. A single anterior oblique photon field for supraclavicular (SCL) nodes was added if indicated. Serial follow-up chest radiographs were reviewed by a chest radiologist. Radiation Therapy Oncology Group (RTOG) toxicity criteria were used for grading SRP and a modified World Health Organization (WHO) grading system was used to evaluate RPT. The overall percentage of the ipsilateral lung volume that received ${\geq}15\;Gy\;(V_{15}),\;20\;Gy\;(V_{20})$, and $30\;Gy\;(V_{30})$ and the mean lung dose (MLD) were calculated. We divided the ipsilateral lung into two territories, and defined separate DVH parameters, i.e., $V_{15\;TNGT},\;V_{20\;TNGT},\;V_{30\;TNGT},\;MLD_{TNGT}$, and $V_{15\;SCL},\;V_{20\;SCL},\;V_{30SCL},\;MLD_{SCL}$ to assess the relationship between these parameters and RPT. $\underline{Results}$: Four patients (2.1%) developed SRP (three with grade 3 and one with grade 2, respectively). There was no significant association of SRP with clinical parameters such as, age, pre-existing lung disease, smoking, chemotherapy, hormonal therapy and regional RT. When 137 patients treated with 3D-RTP were evaluated, 13.9% developed RPT in the tangent (TNGT) territory and 49.2% of 59 patients with regional RT developed RPT in the SCL territory. Regional RT (p<0.001) and age (p=0.039) was significantly correlated with RPT. All DVH parameters except for $V_{15\;TNGT}$ showed a significant correlation with RPT (p<0.05). $MLD_{TNGT}$ was a better predictor for RPT for the TNGT territory than $V_{15\;SCL}$ for the SCL territory. $\underline{Conclusion}$: The incidence of SRP was acceptable with the RT technique that was used. Age and regional RT were significant factors to predict RPT. The DVH parameter was good predictor for RPT for the SCL territory while $MLD_{TNGT}$ was a better predictor for RPT for the TNGT territory.
Kim, Yongwon;Lee, Jiwan;Woo, Soyoung;Kim, Soohong;Lee, Jongjin;Kim, Seongjoon
Journal of Korea Water Resources Association
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v.55
no.12
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pp.1041-1052
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2022
This study is to estimate the optimal ecological flow and analysis the spatial distribution of fish habitat for Andong dam downstream reach (4,565.7 km2) using PHABSIM (Physical Habiat Simulation System) and River2D. To establish habitat models, the cross-section informations and hydraulic input data were collected uisng the Nakdong river basic plan report. The establishment range of PHABSIM was set up about 410.0 m from Gudam streamflow gauging station (GD) and about 6.0 km including GD for River2D. To select representative fish species and construct HSI (Habitat Suitability Index), the fish survey was performed at Pungji bridge where showed well the physical characteristics of target stream located downstream of GD. As a result of the fish survey, Zacco platypus was showed highly relative abundance resulting in selecting as the representative fish species, and HSI was constructed using physical habitat characteristics of the Zacco platypus. The optimal range of HSI was 0.3~0.5 m/s at the velocity suitability index, 0.4~0.6 m at the depth suitability index, and the substrate was sand to fine gravel. As a result of estimating the optimal ecological flow by applying HSI to PHABSIM, the optimal ecological flow for target stream was 20.0 m3/sec. As a result of analysis two-dimensional spatial analysis of fish habitat using River2D, WUA (Weighted Usable Area) was estimated 107,392.0 m2/1000 m under the ecological flow condition and it showed the fish habitat was secured throughout the target stream compared with Q355 condition.
3D QSAR studies for the fungicidal activities against resistive phytophthora blight (RPC; 95CC7303) and sensitive phytophthora blight (Phytopthora capsici) (SPC; 95CC7105) by a series of new 2-alkoxyphenyl-3-phenylthioisoindoline-1-one derivatives (X: A=propynyl & B=2-chloropropenyl) were studied using comparative molecular field analyses (CoMFA) methodology. The CoMFA models were generated from the two different alignment, atom based fit (AF) alignment and field fit (FF) alignment. The atom based alignment exhibited a higher statistical results than that of field fit alignment. The best models, A3 and A7 using combination fields of H-bond field, standard field, LUMO and HOMO molecular orbital field as additional descriptors were selected to improve the statistic of the present CoMFA models. The statistical results of the two models showed the best predictability of the fungicidal activities based on the cross-validated value $q^2\;(r^2_{cv.}=RPC:\;0.625\;&\;SPC:\;0.834)$, non cross-validated value $(r^2_{ncv.}=RPC:\;0.894\;&\;SPC:\;0.915)$ and PRESS value (RPC: 0.105 & SPC: 0.103), respectively. Based on the findings, the predictive ability and fitness of the model for SPC was better than that of the model for RPC. The fugicidal activities exhibited a strong correlation with steric $(66.8{\sim}82.8%)$, electrostatic $(10.3{\sim}4.6%)$ and molecular orbital field (SPC: HOMO, 12.6% and RPC: LUMO, 22.9%) factors of the molecules. The novel selective character for fungicidal activity between two fungi depend on the positive charge of ortho, meta-positions on the N-phenyl ring and size of hydrophilicity of a substituents on the S-phenyl ring.
We conducted a three-dimensional numerical simulation by using the FLOW-3D, with RANS as the governing equation, in an effort to track the dam-break wave.immediately after a dam break.in areas surrounding where the dam break took place as well as the bed change caused by the dam-break wave. In particular, we computed the bed change in the movable bed and compared the variation in flood wave induced by the bed change with our analysis results in the fixed bed. The analysis results can be summarized as follows: First, the analysis results on the flood wave in the L-shaped channel and on the flood wave and bed change in the movable-bed channel successfully reproduce the findings of the hydraulic experiment. Second, the concentration of suspended sediment is the highest in the front of the flood wave, and the greatest bed change is observed in the direct downstream of the dam where the water flow changes tremendously. Generated in the upstream of the channel, suspended sediment results in erosion and sedimentation alternately in the downstream region. With the arrival of the flood wave, erosion initially prove predominant in the inner side of the L-shaped bend, but over time, it tends to move gradually toward the outer side of the bend. Third, the flood wave in the L-shaped channel with a movable bed propagates at a slower pace than that in the fixed bed due to the erosion and sedimentation of the bed, leading to a remarkable increase in flood water level.
Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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v.33
no.1
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pp.31-43
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2015
This study had been aimed to conduct the camera calibration on VLBI antenna in the Space Geodetic Observation Center of Sejong City with a low-cost digital camera, which embedded in a mobile phone to determine the three-dimension position coordinates of the VLBI antenna, based on stereo images. The initial values for the camera calibration have been obtained by utilizing the Direct Linear Transformation algorithm and the commercial digital photogrammetry system, PhotoModeler $Scanner^{(R)}$ ver. 6.0, respectively. The accuracy of camera calibration results was compared with that the camera calibration results, acquired by a bundle adjustment with nonlinear collinearity condition equation. Although two methods showed significant differences in the initial value, the final calibration demonstrated the consistent results whichever methods had been performed for obtaining the initial value. Furthermore, those three-dimensional coordinates of feature points of the VLBI antenna were respectively calculated using the camera calibration by the two methods to be compared with the reference coordinates obtained from a total station. In fact, both methods have resulted out a same standard deviation of $X=0.004{\pm}0.010m$, $Y=0.001{\pm}0.015m$, $Z=0.009{\pm}0.017m$, that of showing a high degree of accuracy in centimeters. From the result, we can conclude that a mobile phone camera opens up the way for a variety of image processing studies, such as 3D reconstruction from images captured.
Enlargement is an inherent property of X-rays which occurs when straight hues diverse from small a focal spot. The purpose of the present study was to evaluate the validity of the correction of gonial angle width enlarged on frontal cephalogram, using frontal and lateral cephalograms taken orthogonally from each other. In 40 adult individuals, frontal and lateral cephalograms were taken at a $90^{\circ}$ angle using the Head Posture Aligner. The angle width was measured on the frontal cephalogram and subsequently. the corrected angle width was calculated using the magnification rate of two cephalograms. Measured and corrected angle widths were compared with the measurement from the 3D CT image. The measurement or the frontal cephalogram showed a 9.10mm of enlargement on average ranging from 7.92 to 11.31mm. Corrected angle width measurement showed a 0.14mm difference with the 3D CT image measurement, which was not statistically significant. The results of the study indicate that actual au91e width can be approached through calculation using frontal and lateral cephalograms taken orthogonally with the help of the Head Posture Aligner The study also showed that the magnitude of correction error did not show a significant correlation with the amount of menton deviation, and it suggests that the present correction method is valid even in individuals with severe facial asymmetry.
Journal of the Korean Association of Oral and Maxillofacial Surgeons
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v.36
no.5
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pp.402-407
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2010
Introduction: The planning of implant surgery is an important factor for the implant prosthesis. Stereolithographic (SLA) surgical stents based on a computer simulation are quite helpful for clinicians to perform the surgery as planned. Although many clinical and technical trials have been performed for computed tomography (CT)-guided implant stents to improve the surgical procedures and prosthetic treatment, there are still many problems to solve. We developed a system of a surgical guide based on 3 dimensional (3D) CT for implant therapy and achieved satisfactory results in the terms of planning and operation. Materials and Methods: Fifteen patients were selected and 30 implant fixtures were installed. The preoperative CT data for surgical planning were prepared after obtaining informed consent. Surgical planning was performed using the simulation program, Ondemend3D In2Guide. The stents were fabricated based on the simulation data containing information of the residual bone, the location of the nerve, and the expected design of the prostheses. After surgery with these customized stents, the accuracy and reproducibility of implant surgery were evaluated based on the computer simulation. The data of postoperative CT were used to confirm this system using the image fusion technique and compare the implant fixtures between the planned and implanted. Results: The mean error was 1.18 (${\pm}0.73$) mm at the occlusal center, 1.23 (${\pm}0.67$) mm at the apical center, and the axis error between the two fixtures was $3.25^{\circ}C$ (${\pm}3.00$). These stents showed superior accuracy in maxilla cases. The lateral side error at the apical center was significantly different from the error at the occlusal center but there were no significant differences between the premolars, 1st molars and 2nd molars. Conclusion: SLA surgical stents based on a computer simulation have the satisfactory accuracy and are expected to be useful for accurate planning and surgery if some errors can be improved.
The purpose of this study was to the determine the optimal torques values to tighten the retaining screw. 3-different implant system tested were as follows : Branemark implant system$(3.75mmD{\times}100mm)$, Steri-Oss implant system$(3.8mmD{\times}10mm)$. One fixtures of each implant system was mounted into the epoxy resin block and abutment/superstructure complex was constructed. Eighty dental college students(male : 40, female : 40) of Chosun University were selected and were asked to tighten the retaining screws. Abutment/superstructure complex of each implant system was tightened to the maximum torque by use of hand-held screw driver, and then torque value was measured with torque value was measured with torque driver(Tohnichi torque driver, model 20 FTD, Tohnichi MFG, Co., LTD., Tokyo, Japan). Abutment/superstructure complex of each implant system was titghtened to each torque of 10 N-cm, 20 N-cm and 30 N-cm, and then the dynamic load(vertical & diagonal load) was applied to the abutment / superstructure complex. The gap between abutment/superstrure in each implant system was measured with 3-dimensional measuring microscope(model No. 850, Germany). The results were as follow : 1. Torque values according to the individual subjects showed wide range. 2. Torque values according to sex showed statistical significant difference. Those are as follows : in case of male, $9.38{\pm}2.93$ N-cm ; incase of female, $7.80{\pm}2.25$ N-cm. 3. Torque values according t implant systems showed statistical significant difference. Those are as follows : in ase of Branemark implant system, $6.54{\pm}1.54$ N-cm : in ase of Steri-Oss implant system, $10.1{\pm}2.88$ N-cm ; in case of IMZ implant system, $9.18{\pm}2.17$ N-cm. 4. The more torque value of tightening screw was increased, the less the gap was after the vertical and diagonal loading. 5. The gap after the diagonal loading was greater than that after the vertical loading. 6. The magnitude of gap between abutment/superstructure in order of IMZ, Steri-Oss, Branemark implant system after the verical and diagonal loading. 7. The gap under the diagonal loading after applying 30 N-cm torque showed no statistical significant difference in cases of the Branemark system and the Steri-Oss implant system but it showed significant different in case of the IMZ implant system.
Journal of the Korea Academia-Industrial cooperation Society
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v.20
no.11
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pp.13-18
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2019
The DEM(Digital Elevation Model) is a three-dimensional spatial information that stores the height of the terrain as a numerical value. This means the elevation of the terrain not including the vegetation and the artifacts. The DEM is used in various fields, such as 3D visualization of the terrain, slope, and incense analysis, and calculation of the quantity of construction work. Recently, many studies related to the construction of 3D geospatial information have been conducted, but research related to DEM generation is insufficient. Therefore, in this study, a DEM was constructed using a MMS (Mobile Mapping System), UAV image, and UAV LiDAR (Light Detection And Ranging), and the accuracy evaluation of each result was performed. As a result, the accuracy of the DEM generated by MMS and UAV LiDAR was within ± 4.1cm, and the accuracy of the DEM using the UAV image was ± 8.5cm. The characteristics of MMS, UAV image, and UAV LiDAR are presented through a comparison of data processing and results. The DEM construction using MMS and UAV can be applied to various fields, such as an analysis and visualization of the terrain, collection of basic data for construction work, and service using spatial information. Moreover, the efficiency of the related work can be improved greatly.
Journal of the Korea Academia-Industrial cooperation Society
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v.19
no.10
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pp.121-127
/
2018
A system for diagnosing surface defects of long and large pipe inner overlay welds, 1m in diameter and 6m in length, was developed using a Liquid Penetrant Test (PT). First, CATIA was used to model all major units and PT machines in 3-dimensions. They were used for structural strength analysis and strain analysis, and to check the motion interference phenomenon of each unit to produce two-dimensional production drawings. Structural strength analysis and deformation analysis using the ANSYS results in a maximum equivalent stress of 44.901 MPa, which is less than the yield tensile strength of SS400 (200 MPa), a material of the PT Machine. An examination of the performance of the developed equipment revealed a maximum travel speed of 7.2 m/min., maximum rotational speed of 9 rpm, repeatable position accuracy of 1.2 mm, and inspection speed of $1.65m^2/min$. The results of the automatic PT-inspection system developed to check for surface defects, such as cracks, porosity, and undercut, were in accordance with the method of ASME SEC. V&VIII. In addition, the results of corrosion testing of the overlay weld layer in accordance with the ferric chloride fitting test by the method of ASME G48-11 indicated that the weight loss was $0.3g/m^2$, and met the specifications. Furthermore, the chemical composition of the overlay welds was analyzed according to the method described in ASTM A375-14, and all components met the specifications.
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