• Journal of Periodontal and Implant Science
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• v.53 no.1
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• pp.20-37
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• 2023

Purpose: Our pilot study showed that a 3-dimensional dual drug delivery scaffold (DDDS) loaded with Chinese herbs significantly increased the regenerated bone volume fraction. This study aimed to confirm the synergistic anti-inflammatory and osteogenic preclinical effects of this system. Methods: The targets and pathways of parthenolide and naringin were predicted. Three cell models were used to assess the anti-inflammatory effects of parthenolide and the osteogenic effects of naringin. First, the distance between the cementoenamel junction and alveolar bone crest (CEJ-ABC) and the bone mineral density (BMD) of surgical defects were measured in a rat model of periodontitis with periodontal fenestration defects. Additionally, the mRNA expression levels of matrix metallopeptidase 9 (MMP9) and alkaline phosphatase (ALP) were measured. Furthermore, the number of inflammatory cells and osteoclasts, as well as the protein expression levels of tumor necrosis factor-alpha (TNF-α) and levels of ALP were determined. Results: Target prediction suggested prostaglandin peroxidase synthase (PTGS2) as a potential target of parthenolide, while cytochrome P450 family 19 subfamily A1 (CYP19A1) and taste 2 receptor member 31 (TAS2R31) were potential targets of naringin. Parthenolide mainly targeted inflammation-related pathways, while naringin participated in steroid hormone synthesis and taste transduction. In vitro experiments revealed significant antiinflammatory effects of parthenolide on RAW264.7 cells, and significant osteogenic effects of naringin on bone marrow mesenchymal stem cells and MC3T3-E1 cells. DDDS loaded with parthenolide and naringin decreased the CEJ-ABC distance and increased BMD and ALP levels in a time-dependent manner. Inflammation was significantly alleviated after 14 days of DDDS treatment. Additionally, after 56 days, the DDDS group exhibited the highest BMD and ALP levels. Conclusions: DDDS loaded with parthenolide and naringin in a rat model achieved significant synergistic anti-inflammatory and osteogenic effects, providing powerful preclinical evidence.

• Composites Research
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• v.36 no.2
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• pp.92-100
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• 2023

In this paper, a machine learning and deep learning model for the design of circuit analog (CA) radar absorbing structure with a cross-dipole pattern on a glass fiber fabric reinforced plastic is presented. The proposed model can directly calculate reflection loss in the Ku-band (12-18 GHz) without three-dimensional electromagnetic numerical analysis based on the geometry of the Cross-Dipole pattern. For this purpose, the optimal learning model was derived by applying various machine learning and deep learning techniques, and the results calculated by the learning model were compared with the electromagnetic wave absorption characteristics obtained by 3D electromagnetic wave numerical analysis to evaluate the comparative advantages of each model. Most of the implemented models showed similar calculated results to the numerical results, but it was found that the Fully-Connected model could provide the most similar calculated results.

• Journal of Dental Rehabilitation and Applied Science
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• v.24 no.4
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• pp.389-403
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• 2008

In Angle's Class III malocclusion, which has higher incidence in Korean than Western, depressed midfacial profile with protruded lower lips and mandible may give rise to many functional, esthetic, psychological, social problems. Due to the different malocclusion incidence according to racial differences, many previous studies focused on the relationship between Class II malocclusion and nasal airway obstruction. Previous studies used lateral cephalography which has limitations of 2 dimensional image with projection error and identification error. Therefore, the purpose of this study was to analyze morphologic differences in the nasal airway between normal occlusion and Angle's Class III malocclusion patients using 3-dimensional facial computed tomography. Thirteen normal occlusion(7 men and 6 women) and sixteen skeletal Class III(7 men and 9 women) patients were selected and 3-dimensional facial computed tomography taking was performed. Comparison between two group in volume and sectional area of nasal airway were carried out. The results were followed. 1. In the comparison of absolute nasal airway volume, oropharyngeal space of experimental group were larger than control group but there are no significant difference in other. 2. In the comparison of relative nasal airway volume, oropharyngeal space of experimental group were larger than control group but there are no significant difference in other. 3. In the oropharyngeal space width on frontal and lateral view, the similar tendency was revealed between two groups. 4. In the lateral curvature of nasal airway, the similar tendency was revealed between two groups.

• Korean Chemical Engineering Research
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• v.47 no.5
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• pp.630-638
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• 2009

A computational fluid dynamics(CFD) model is developed and validated with on-site experiments for a urea-based SNCR(selective non-catalytic reduction) process to reduce the nitrogen oxides($NO_x$) in a municipal incinerator. The three-dimensional turbulent reacting flow CFD model having a seven global reaction mechanism under the condition of low CO concentration and 12% excess air and droplet evaporation is used for fluid dynamics simulation of the SNCR process installed in the incinerator. In this SNCR process, urea solution and atomizing air were injected into the secondary combustor, using one front nozzle and two side nozzles. The exit temperature($980^{\circ}C$) of simulation has the same value as in situ experiment one. The $NO_x$ reduction efficiencies of 57% and 59% are obtained from the experiment and CFD simulation, respectively at NSR=1.8(normalized stoichiometric ratio) for the equal flow rate ratio from the three nozzles. It is observed in the CFD simulations with varying the flowrate ratio of the three nozzles that the injection of a two times larger front nozzle flowrate than the side nozzle flowrate produces 8% higher $NO_x$ reduction efficiency than the injection of the equal ratio flowrate in each nozzle.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• v.27 no.2
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• pp.111-117
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• 2001

There are three designs of thread form in screw type implants: V-thread, Reverse buttress thread and Square thread. The purpose of this study was to find out how thread form designs have an influence on the equivalent stress, equivalent strain, maximum shear stress and maximum shear strain and which design of thread form generates more maximum equivalent stress and strain. 3-D finite element analysis was used to evaluate the stress and strain patterns of three tread types. The results of this study were as follow. 1. Under the 200N of axial load, the value of maximum equivalent stress is smallest in square thread and there is no significant difference between that of V thread and reverse buttress thread. 2. Under the 200N of axial load, the value of maximum equivalent strain is largest in V thread and smallest in square thread. 3. Under the 200N of axial load, the value of maximum shear stress is smallest in square thread and there is no significant difference between that of V thread and reverse buttress thread. 4. Under the 200N of axial load, the value of maximum equivalent strain is largest in V thread and there is no significant difference between that of square thread and reverse buttress thread. 5. Above results show that the square thread has special advantages in stress and strain compared with other thread types, especially in shear stess which is most determinant to implant-bone interface. Considering the superior biomechanical properties of square form implant, we presume that square form implant has better clinical results than the other types of implants in the same clinical conditions.

• Annals of Clinical Neurophysiology
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• v.1 no.2
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• pp.112-117
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• 1999

Background : Posterior tibial nerve somatosensory evoked potentials (PTSEP) have cortical potentials on primary sensory area of foot around 40 msec. The direct cortical recordings of the cortical potentials shows high voltage positive wave on medial hemisphere, especially on paracentral lobule (PCL). However, it is so difficult to record the potential directly on PCL that the cortical potential of PTSEP is not well understood. We investigated the cortical potential of PTSEP on subdural electrodes. Methods : We recorded cortical potentials to posterior tibial nerve stimulation on subdural electrodes which were on medial hemisphere near PCL in 15 intractable neocortical epilepsy patients. The numbers of subdural electrodes were 8 in 10 subjects ($1{\times}8array$) and 16 in 5 subjects ($2{\times}8arrays$). Seven subjects had three-dimensional imaging fusion (3D-fusion) of MRI and the electrodes using Analyze program. We investigated the amplitude, latency, polarity, and phase of the waves regarding location. Results : The waves had maximal amplitude on PCL in 4 subjects, precuneus in 1, cingulate gyrus nearest to PCL in 2 among 7 subjects with 3D-fusion. Also the electrodes were located on posterior area of PCL (2 out of 2 subjects with more than two electrodes put on PCL in 3D-fusion) and superior area of it (5 out of 5 subjects with $2{\times}8arrays $). All the high (more than 20 uV) amplitude around 40msec had positive polarity in 7 subjects. The phase reversals were detected between the electrodes with the highest amplitude and the just posterior (2 subjects) or anterior (6 subjects) located electrodes. The just posterior located electrodes had sharper phase reversal than the anterior one. Conclusion : PTSEP might have maximal amplitude of cortical potentials on the more superior and posterior area of PCL. The highest amplitude potential has positivity. The wave with maximal amplitude could have phase reversal of cortical potentials with surrounding electrodes, especially shaper with posterior part than with anterior one.

• Journal of Korean Society for Geospatial Information Science
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• v.24 no.3
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• pp.59-66
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• 2016

The 2011 debris flow in Mt. Umyeonsan in Seoul, South Korea caused significant damages to the surrounding urban area, unlike other similar incidents reported to have occurred in the past in the country's mountainous regions. Accordingly, landslides and debris flows cause damage in various surroundings, regardless of mountainous area and urban area, at a great speed and with enormous impact. Hence, many researchers attempted to forecast the extent of impact of debris flows to help minimize the damage. The most fundamental part in forecasting the impact extent of debris flow is to understand the debris flow behavior and sedimentation mechanism in complex three-dimensional topography. To understand sedimentation mechanism, in particular, it is necessary to calculate the amount of energy and erosion according to debris flow behavior. The previously developed debris flow models, however, are limited in their ability to calculate the erosion amount of debris flow. This study calculated the extent of damage caused by a massive debris flow that occurred in 2011 in Seoul's urban area adjacent to Mt. Umyeonsan by using DEM, created from aerial photography and airborne LiDAR data, for both before and after the damage; and developed and compared a debris flow behavioral analysis model that can assess the amount of erosion based on energy theory. In addition, simulations using the existing debris flow model (RWM, Debris 2D) and a comprehensive comparison of debris flow-stricken areas were performed in the same study area.

• Journal of Dental Rehabilitation and Applied Science
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• v.27 no.2
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• pp.247-251
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• 2011

Botulinum toxin type A (BoNT-A) is used for treating bilateral masseter hypertrophy since 1994. Recently there have been more clinical studies in this area, with some authors reporting that BoNT-A can reduce the size of the masseter muscle, as documented by photography, ultrasonography, computed tomography, and 3D(three dimensional) laser scan. However, earlier studies were only for bilateral masseter hypertrophy cases, not for unilateral masseter hypertrophy cases. The aim of this study was to use 3D laser scanning to evaluate changes in the external facial contour induced by unilateral BoNT-A injection. BoNT-A was injected into hypertrophic masseter muscle unilaterally in 10 patients with asymmetric masseter hypertrophy. The clinical effects of unilaterally injected BoNT-A were evaluated before the injection and 4, 8, and 12weeks after the injection using 3D laser scan. And the mean values of both sides (injection and non-injection sides) were compared with. At injection side, mean values of the volume and the bulkiest height at each time point diminished significantly between pre-injection and 4, 8, and 12weeks post-injection. At non-injection side, in contrast, mean values of the volume and the bulkiest height diminished also but less than that of injected side, and there was no statistical significance. In this limited study, we concluded that the unilaterally BoNT-A injection side showed greater mean values of the reduction of muscle volume than non-injection side at 4, 8, and 12 weeks after the injection.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.17 no.8
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• pp.1908-1918
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• 2013

Free-view, auto-stereoscopic video service is a next generation broadcasting system which offers a three-dimensional video, images of the various point are needed. This paper proposes a method that parallelizes the algorithm for arbitrary intermediate view-point image fast generation and make it faster using General Propose Graphic Processing Unit(GPGPU) with help of the Compute Unified Device Architecture(CUDA). It uses a parallelized stereo-matching method between the leftmost and the rightmost depth images to obtain disparity information and It use data calculated disparity increment per depth value. The disparity increment is used to find the location in the intermediate view-point image for each depth in the given images. Then, It is eliminate to disocclusions complement each other and remaining holes are filled image using hole-filling method and to get the final intermediate view-point image. The proposed method was implemented and applied to several test sequences. The results revealed that the quality of the generated intermediate view-point image corresponds to 30.47dB of PSNR in average and it takes about 38 frames per second to generate a Full HD intermediate view-point image.

• Journal of the Korean Society of Clothing and Textiles
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• v.34 no.6
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• pp.955-968
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• 2010

Three-dimensional body data has been used in many industry fields including the apparel industry. This research used data from a study of the changes in lower body girth measurements from a 3D scan study of 25 female subjects aged 18 to 24 in four postures; a standing posture, a $120^{\circ}$ knee bend posture, a one pace stepping posture, and a sitting posture with a $90^{\circ}$ knee bend. We used the information on the difference between standing and seated measurements to adjust ease values for pants patterns an evaluation of the appearance, and the comfort of the pants. Waist girth in the sitting posture increased 8% compared to a standing posture and the hip girth measurement increased 7%. A basic pants pattern (pants A) with 2.4cm ease at the waist and 2.6cm ease at the hip was developed and a pants pattern (pants B) was developed using the rates of lower body girth change with a 5.7cm ease (8% change) at the waist and 7cm ease (7% change) at the hip. The appearance assessment items of pants A in a standing posture were higher than pants B. On the other hand, most appearance assessment items of pants B in a sitting posture were higher than pants A, especially the ease of pants back waistline and the appearance of the whole back. Comfort assessment items of pants B in both standing and sitting postures were higher than the comfort assessment items for pants A, especially the location of pants waistline, the ease of pants at the waistline, and the ease at the abdomen. In order to find the best level of ease for better appearance and comfort in both standing and sitting postures, 20 pants were constructed with ease values at the waist and hip in increments of 1.1cm in the range between the ease values of pants A and pants B. A fit test was conducted to compare the average appearance and comfort ratings that identified the pants with the best ease values at the waist and hip. The highest total mean was achieved in the pants with a waist ease of 4.6cm and hip ease of 4.8cm.