• Tissue Engineering and Regenerative Medicine
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• v.19
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• pp.1099-1111
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• 2022

Background: Bone marrow-derived mesenchymal stem cells (BMSCs) and bone morphogenetic protein-2 (BMP-2) have been studied for bone repair because they have regenerative potential to differentiate into osteoblasts. The development of injectable and in situ three-dimensional (3D) scaffolds to proliferate and differentiate BMSCs and deliver BMP-2 is a crucial technology in BMSC-based tissue engineering. Methods: The proliferation of mouse BMSCs (mBMSCs) in collagen/poly-γ-glutamic acid (Col/γ-PGA) hydrogel was evaluated using LIVE/DEAD and acridine orange and propidium iodide assays. In vitro osteogenic differentiation and the gene expression level of Col/γ-PGA(mBMSC/BMP-2) were assessed by alizarin red S staining and quantitative reverse-transcription polymerase chain reaction. The bone regeneration effect of Col/γ-PGA(mBMSC/BMP-2) was evaluated in a mouse calvarial bone defect model. The cranial bones of the mice were monitored by micro-computed tomography and histological analysis. Results: The developed Col/γ-PGA hydrogel showed low viscosity below ambient temperature, while it provided a high elastic modulus and viscous modulus at body temperature. After gelation, the Col/γ-PGA hydrogel showed a 3D and interconnected porous structure, which helped the effective proliferation of BMSCs with BMP-2. The Col/γ-PGA (mBMSC/BMP-2) expressed more osteogenic genes and showed effective orthotopic bone formation in a mouse model with a critical-sized bone defect in only 3-4 weeks. Conclusion: The Col/γ-PGA(mBMSC/BMP-2) hydrogel was suggested to be a promising platform by combining collagen as a major component of the extracellular matrix and γ-PGA as a viscosity reducer for easy handling at room temperature in BMSC-based bone tissue engineering scaffolds.

• Spatial Information Research
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• v.21 no.3
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• pp.89-101
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• 2013

Recently, importance of indoor space is on the rise, as larger and more complex buildings are taking place due to development of building technology. Accordingly, range of the target area of spatial information service is rapidly expanding from outdoor space to indoor space. Various demands for indoor spatial information are expected to be created in the future through development of high technologies such as IT Mobile and convergence with various area. Thus this research takes a look at available methods for building indoor spatial information and then builds high accuracy three-dimensional indoor spatial information using indoor high accuracy laser survey and 3D vector process technique. The accuracy of built 3D indoor model is evaluated by overlap analysis method refer to a digital map, and the result showed that it could guarantee its positional accuracy within 0.04m on the x-axis, 0.06m on the y-axis. This result could be used as a fundamental data for building indoor spatial data and for integrated use of indoor and outdoor spatial information.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.21 no.6
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• pp.625-633
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• 2020

this study, an expert AHP questionnaire analysis of public and private groups was conducted to take into consideration the requirements for realistic disaster services. Considered are public areas that manage disasters like fires and earthquakes that can be a major threat to national safety, as well as private areas that mainly develop disaster-related technologies. In the questionnaire, the public respondents valued accurate disaster situation information (ranked 4th and 6th) for citizens (1st), managers (3rd), and related organizations (2nd); the private sector highly valued the importance of three-dimensional (3D) control (ranked 1st, 3rd, and 5th) using future technologies. This study suggests the realization of a disaster-response service that meets the needs of public safety and technological innovation based on a 3D safety state information platform. We anticipate that this study will provide useful data for applying technology and for establishing detailed scenarios during the test bed and commercialization phases. We also expect that further studies will be conducted, such as the practical application and operation of realistic disaster response services, on the financial resources for the proliferation of local governments, and on policy support measures.

• Journal of the Korean Institute of Landscape Architecture
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• v.51 no.2
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• pp.1-11
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• 2023

This study intended to develop a technique for quantitatively and 3-dimensionally predicting the potential failure zone and impulse that may occur when trees are fall down. The main outcomes of this study are as follows. First, this study established the potential failure zone and impulse calculation formula in order to quantitatively calculate the risks generated when trees are fallen down. When estimating the potential failure zone, the calculation was performed by magnifying the height of trees by 1.5 times, reflecting the likelihood of trees falling down and slipping. With regard to the slope of a tree, the range of 360° centered on the root collar was set in the case of trees that grow upright and the range of 180° from the inclined direction was set in the case of trees that grow inclined. The angular momentum was calculated by reflecting the rotational motion from the root collar when the trees fell down, and the impulse was calculated by converting it into the linear momentum. Second, the program to calculate a potential failure zone and impulse was developed using Rhino3D and Grasshopper. This study created the 3-dimensional models of the shapes for topography, buildings, and trees using the Rhino3D, thereby connecting them to Grasshopper to construct the spatial information. The algorithm was programmed using the calculation formula in the stage of risk calculation. This calculation considered the information on the trees' growth such as the height, inclination, and weight of trees and the surrounding environment including adjacent trees, damage targets, and analysis ranges. In the stage of risk inquiry, the calculation results were visualized into a three-dimensional model by summarizing them. For instance, the risk degrees were classified into various colors to efficiently determine the dangerous trees and dangerous areas.

• The Journal of the Korea Contents Association
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• v.5 no.4
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• pp.133-140
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• 2005

Culture Technology is the basic technology which produces cultural contents in a narrow sense. All nations do their best in order to create new contents which can form international and cultural sympathy. If a variety of contents are created by applying Korean proper cultural heritages, they will be creative and competitive internationally. Therefore, technology of original cultural restoration is an essential and crucial skill. In this paper, 'gilt bronze dragon-phoenix ring-pommeled sword', a cultural heritage of baekje age, will be restored to the original form digitally on the basis of three-dimensional shape-information processing technology and the scientifically analyzed data. First of all, data from three-dimensional scanning is revised using stuffing and smoothing methods after sampling, extracting characteristics, and align. Then, they are modeled in a curved surface with NURBS and B-Spline. Secondly, textures are edited by estimating the color of components and the quality of materials, and then they are mapped. Original form model which was made was revised and corrected by specialists' examinations. The digitally revised ring-pommeled sword was combined with information technology, and it can be used to revise damaged cultural heritages by constructing formal database of ring-pommeled sword with regard to age, area and type. It can be also used as educational contents in archaeology or preservation science and cultural contents such as movies, broadcasts, games, animations and so on.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.35 no.4
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• pp.863-874
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• 2015

The use of pile reinforcement is considered as one of the most promising techniques for improving load carrying capacity of piles in offshore area. In this study, to consider the horizontal and uplift bearing capacity of submerged breakwater bearing pile, exclusive analysis on load-transfer behaviour of pile was conducted. First of all, check the reinforcing effect from the three-dimensional finite element method, and estimate load transfer curve (ground reaction force). Based on these results, the reinforcing effect was quantified by estimating the coefficients of horizontal and uplift reinforcement of reinforced piles. Load transfer function with consideration of the reinforcing effect was proposed from estimated coefficients. A comparison of the analysis using the proposed load transfer function with three-dimensional finite element analysis has resulted that the proposed load transfer function is displaying good accuracy of predicting behavior of the load transfer between the pile and soil reinforcement. Interpretation of the submerged structure by applying a load transfer function considering the reinforcing effect, has shown that the reinforced pile's shear, bending moment and displacement are less than that of non-reinforced piles, while the subgrade reaction modulus arises greater. Thus, it is expected to be relatively cost effective in terms of design.

• Journal of the Korean Society of Surveying, Geodesy, Photogrammetry and Cartography
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• v.32 no.5
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• pp.551-560
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• 2014

Compare to other industrial sites, the civil construction work not only takes longer time but also has made of complicated processes, such as the integrated management, process control, and quality control until the completion. However, it is hard to take control the construction sites, since numerous issues are always emerged. The study purposes on providing the dataset to synthetically manage and monitor the civil construction site, main design, drawings, process, construction cost, and others at real-time by using the low altitude close-range aerial images, based on UAV, and the GPS surveying method for treating the three-dimensional spatial information quickly and accurately. As a result, we could provide the latest information for the quick decision-making following from planning to completion of the construction, and objective site evaluation by the high-resolution three-dimensional spatial information and drawings. Also, the present map, longitudinal map, and cross sectional view are developed to provide various datasets rapidly, such as earthwork volume table, specifications, and transition of ground level.

• Journal of Korean Tunnelling and Underground Space Association
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• v.16 no.1
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• pp.105-115
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• 2014

A numerical analysis on the smoke behavior and evacuee safety has been performed with computational fluid dynamics. The purpose of this study is to build computational processes for an evacuation and prevention of a fire disaster of a 3 km-length tunnel in Korea. To save computational cost, 1.5 km of the tunnel that can include a few cross-passing tunnels is considered. We are going to assess the fire safety in a road tunnel according to the smoke level, which consists of the smoke density and the height from the floor. The smoke density is obtained in detail from three-dimensional unsteady CFD analysis. To obtain proper temperature distributions on the tunnel wall, one-dimensional conduction equation is considered instead of an adiabatic wall boundary or a constant heat flux. The tunnel considered in this study equips the cross passing tunnels for evacuees every 250 m. The distance is critical in both safety and economy. The more cross passing tunnels, the more safe but the more expensive. Three different jet fan operations can be considered in this study; under- and over-critical velocities for normal traffic condition and 0-velocoty operation for the traffic congestion. The SE (smoke environment) level maps show a smoke environment and an evacuating behavior every moment.

• The korean journal of orthodontics
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• v.41 no.6
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• pp.423-430
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• 2011

Objective: To evaluate the extent and aspect of stress to the cortical bone after application of a lateral force to a two-component orthodontic mini-implant (OMI, mini-implant) by using three-dimensional finite element analysis (FEA). Methods: The 3D-finite element models consisted of the maxilla, maxillary first molars, second premolars, and OMIs. The screw part of the OMI had a diameter of 1.8 mm and length of 8.5 mm and was placed between the roots of the upper second premolar and the first molar. The cortical bone thickness was set to 1 mm. The head part of the OMI was available in 3 sizes: 1 mm, 2 mm, and 3 mm. After a 2 N lateral force was applied to the center of the head part, the stress distribution and magnitude were analyzed using FEA. Results: When the head part of the OMI was friction fitted (tapped into place) into the inserted screw part, the stress was uniformly distributed over the surface where the head part was inserted. The extent of the minimum principal stress suggested that the length of the head part was proportionate with the amount of stress to the cortical bone; the stress varied between 10.84 and 15.33 MPa. Conclusions: These results suggest that the stress level at the cortical bone around the OMI does not have a detrimental influence on physiologic bone remodeling.

• The Journal of the Acoustical Society of Korea
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• v.43 no.4
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• pp.414-421
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• 2024

In this paper, we design and verify a system that can detect piping leakage noise in an environment with significant reverberation and reflection using a multi-channel acoustic sensor module as a technology to prevent major plant accidents caused by leakage. Four-channel microphones arranged in a tetrahedron are designed as a single sensor module to measure three-dimensional sound intensity vectors. In an environment with large effects of reverberation and reflection, the measurement error of each sensor module increases on average, so after placing multiple sensor modules in the field, measurement results showing locations with large errors due to effects such as reflection are excluded. Using the intersection between three-dimensional vectors obtained from several pairs of sensor modules, the coordinates where the sound source is located are estimated, and outliers (e.g., positions estimated to be outside the site, positions estimated to be far from the average position) are detected and excluded among the points. For achieving aforementioned goal, an excluding algorithm by deciding the outliers among the estimated positions was proposed. By visualizing the estimated location coordinates of the leakage sound on the site drawing within 1 second, we construct and verify a system that can detect the location of the leakage sound in real time and enable immediate response. This study is expected to contribute to improving accident response capabilities and ensuring safety in large plants.