• 제목/요약/키워드: 3A

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3차원 텔레비전의 제품선정 방법 (Method for Selecting a Three Dimensional Television)

  • 변대호
    • 디지털융복합연구
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    • 제11권3호
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    • pp.41-48
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    • 2013
  • 3차원 텔레비전(3DTV)는 이차원 텔레비전(2DTV)을 대체할 새로운 혁신기술로 여러 제조사로부터 다양한 모델이 출시되고 있다. 3DTV는 매력적 요소에도 불구하고 내재된 문제점, 제조사별 기술적 차이점 때문에 소비자들은 제품선정을 위한 복잡한 의사결정 문제에 직면한다. 일반적으로 구매자들은 제품 사양을 비교하는 방식을 사용하지만 3DTV 특성상 실제 체험한 후 선택하는 것이 바람직하다. 본 연구는 소비자들이 3DTV 구매 의사결정을 지원하기 위한 일련의 방법론을 제안한다. 제품선정 기준을 도출하고 계층적분석과정(AHP) 모델을 구축한다. 이용자 테스트 방법을 제안하며 수치적 예제를 통해 제품의 우선순위가 결정되는 과정을 보인다.

Importance of Cytochrome P450 3A4 Conformation for the Activity Stimulation by Cytochrome b5 : Specific Inhibition of Cytochrome P450 3A4 by Zinc (II) Ion

  • Kim, Joon-Sik;Yun, Chul-Ho
    • 대한약학회:학술대회논문집
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    • 대한약학회 2003년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.1
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    • pp.149.3-150
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    • 2003
  • CYP3A4 is the most abundant human CYP and oxidizes a diversity of substrates. including various drugs. steroids. and carcinogens. A variety of metal ions are known to affect microsomal monooxygenase activities. Effects of a series of divalent metal ions on the CYP3A4-catalyzed reaction of reconstituted system containing purified CYP3A4. NADPH-P450 reductase (NPR), and cytochrome b5 (b5) were examined. (omitted)

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Molecular Cloning and Expression of Fusion Proteins Containing Human Cytochrome P450 3As and Rat NADPH-P450 Reductase in Escherichia coli

  • Chun, Young-Jin;Guengerich, F-Peter
    • Toxicological Research
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    • 제18권3호
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    • pp.249-257
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    • 2002
  • Cytochrome P450 3As such as 3A4 and 3A5 metabolize a wide range of pharmaceutical compounds. The vectors for the expression of fusion protein containing an N-terminal human P450 3A4 or P450 3A5 sequences and a C-terminal rat NADPH-cytochrome P450 reductase moiety were constructed. These plasmids were used to express the fusion protein in Escherichia coli DH5$\alpha$ cells. High levels of expression were achieved (100~200 nmol/liter) and the expressed fusion protein in E. coli membranes were catalytically active for nifedipine oxidation, a typical enzymatic activity of P450 3A4. The NADPH-P450 reductase activities of these fusion protein were also determined by measuring reduction of cytochrome c. To fine a specific Inhibitor of P450 3A4 from naturally occurring chemicals, a series of isothiocyanate compounds were evaluated for the inhibitory activity of P450 using the fusion proteins in E. coli membranes. Of the five isothiocyanates (phenethyl isothiocyanate, phenyl isothiocyanate, benzol isothiocyanate, benzoyl isothiocyanate and cyclohexyl isothiocyanate) tested, benzoyl isothiocyanate showed a strong inhibition of P450 3A4 with an $IC_{50}$value of 2.8 $\mu\textrm{M}$. Our results indicate that the self-sufficient fusion protein will be very useful tool to study the drug metabolism and benzyl isothiocyanate may be valuable for characterizing the enzymatic properties of P450 3A4.

La2O3의 메카노케미컬 합성에 의한 LaNiO3결정상 생성 (Mechanochemical Synthesis of LaNiO3 Crystalline Phase from Mixture of La2O3sub> and NiO)

  • 김대영;김강언;이명교;정수태
    • 한국전기전자재료학회논문지
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    • 제16권8호
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    • pp.681-687
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    • 2003
  • The syntheses of LaNiO$_3$Perovskite crystalline phase from mixtures of La$_2$O$_3$and NiO via it mechanochemical(used planetary mill) and a wet ball mill process were investigated. A single and stable LaNiO$_3$perovskite crystalline phase was successfully prepared by using a heat free mechanochemical process which produced a fine amorphous powder, while that phase was not formed in a wet ball mill process which needed heat treatment ranging from 500 to 150$0^{\circ}C$ and produced a coarse powder. It was shown that the LaNiO$_3$ceramics made of the mechanochemically synthesized powder possesed a good metallic characteristic.

단속형 가변적층쾌속조형공정을 이용한 3차원 스캔데이터로부터 3차원 시작품의 쾌속 제작 (Rapid Manufacturing of 3D Prototype from 3D scan data using VLM-ST)

  • 이상호;안동규;김효찬;양동열;박두섭;채희창
    • 한국정밀공학회:학술대회논문집
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    • 한국정밀공학회 2002년도 춘계학술대회 논문집
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    • pp.536-539
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    • 2002
  • The reverse engineering (RE) technology can quickly generate 3D point cloud data of an object by capturing the surface of a model using a 3D scanner. In the rapid prototyping (RP) technology, prototypes are rapidly produced from 3D CAD models in a layer-by-layer additive basis. In this paper, a physical human head shape is duplicated using a new RP process, the Transfer-type Variable Lamination Manufacturing process using expandable polystyrene foam sheet (VLM-ST), after the point cloud data of a human head shape measured from 3D SNX scanner are converted to STL file. From the duplicated human head shape, it has been shown that the VLM-ST process in connection with the 3D scanner is a fast and efficient process in that shapes with free surface, such as the human head shape, can be duplicated with ease. Considering the measurement time and the shape duplication time, the use of 3D SNX scanner and the VLM-ST process is expected to reduce the lead-time fur the development of new products in comparison with the other existing RE-RP connected manufacturing systems.

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Expression, Purification and NMR studies of SH3YL1 SH3 domain

  • Shrestha, Pravesh;Yun, Ji-Hye;Lee, Weon-Tae
    • 한국자기공명학회논문지
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    • 제14권2호
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    • pp.105-116
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    • 2010
  • SH3YL1, a novel protein containing one Src homology 3 domain at the carboxyl terminus was first detected in mouse anagen skin cDNA. This protein had a significant homology with YHRO 16c/Ysc 84, the yeast Src homology 3 domain-containing protein. The sequence identity was remarkable at the carboxyl and amino-terminal Src homology 3 domain, suggesting that the novel protein is a mouse homolog of the yeast protein and thus was termed as SH3YL1. SH3YL1 is composed of two domains, a DUF500 at N-termini and a SH3 domain at C-termini. In our study we cloned the SH3 domain in bacterial expression system in Escherichia coli using pET32a vector with TEV protease cleavage site and purified as a monomer using affinity chromatography. The N-terminal poly-Histidine tag was cleaved with TEV protease and target protein was used for backbone studies. Our study showed that SH3 domain primarily consists of $\beta$-sheet which is in consistence with previous result performed on the truncated SH3 domain of SH3YL1.

Computerized Human Body Modeling and Work Motion-capturing in a 3-D Virtual Clothing Simulation System for Painting Work Clothes Development

  • Park, Gin Ah
    • 패션비즈니스
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    • 제19권3호
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    • pp.130-143
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    • 2015
  • By studying 3-D virtual human modeling, motion-capturing and clothing simulation for easier and safer work clothes development, this research aimed (1) to categorize heavy manufacturing work motions; (2) to generate a 3-D virtual male model and establish painting work motions within a 3-D virtual clothing simulation system through computerized body scanning and motion-capturing; and finally (3) to suggest simulated clothing images of painting work clothes developed based on virtual male avatar body measurements by implementing the work motions defined in the 3-D virtual clothing simulation system. For this, a male subject's body was 3-D scanned and also directly measured. The procedures to edit a 3-D virtual model required the total body shape to be 3-D scanned into a digital format, which was revised using 3-D Studio MAX and Maya rendering tools. In addition, heavy industry workers' work motions were observed and recorded by video camera at manufacturing sites and analyzed to categorize the painting work motions. This analysis resulted in 4 categories of motions: standing, bending, kneeling and walking. Besides, each work motion category was divided into more detailed motions according to sub-work posture factors: arm angle, arm direction, elbow bending angle, waist bending angle, waist bending direction and knee bending angle. Finally, the implementation of the painting work motions within the 3-D clothing simulation system presented the virtual painting work clothes images simulated in a dynamic mode.

Improved Sliding Shapes for Instance Segmentation of Amodal 3D Object

  • Lin, Jinhua;Yao, Yu;Wang, Yanjie
    • KSII Transactions on Internet and Information Systems (TIIS)
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    • 제12권11호
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    • pp.5555-5567
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    • 2018
  • State-of-art instance segmentation networks are successful at generating 2D segmentation mask for region proposals with highest classification score, yet 3D object segmentation task is limited to geocentric embedding or detector of Sliding Shapes. To this end, we propose an amodal 3D instance segmentation network called A3IS-CNN, which extends the detector of Deep Sliding Shapes to amodal 3D instance segmentation by adding a new branch of 3D ConvNet called A3IS-branch. The A3IS-branch which takes 3D amodal ROI as input and 3D semantic instances as output is a fully convolution network(FCN) sharing convolutional layers with existing 3d RPN which takes 3D scene as input and 3D amodal proposals as output. For two branches share computation with each other, our 3D instance segmentation network adds only a small overhead of 0.25 fps to Deep Sliding Shapes, trading off accurate detection and point-to-point segmentation of instances. Experiments show that our 3D instance segmentation network achieves at least 10% to 50% improvement over the state-of-art network in running time, and outperforms the state-of-art 3D detectors by at least 16.1 AP.

Pose-normalized 3D Face Modeling for Face Recognition

  • Yu, Sun-Jin;Lee, Sang-Youn
    • 한국통신학회논문지
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    • 제35권12C호
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    • pp.984-994
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    • 2010
  • Pose variation is a critical problem in face recognition. Three-dimensional(3D) face recognition techniques have been proposed, as 3D data contains depth information that may allow problems of pose variation to be handled more effectively than with 2D face recognition methods. This paper proposes a pose-normalized 3D face modeling method that translates and rotates any pose angle to a frontal pose using a plane fitting method by Singular Value Decomposition(SVD). First, we reconstruct 3D face data with stereo vision method. Second, nose peak point is estimated by depth information and then the angle of pose is estimated by a facial plane fitting algorithm using four facial features. Next, using the estimated pose angle, the 3D face is translated and rotated to a frontal pose. To demonstrate the effectiveness of the proposed method, we designed 2D and 3D face recognition experiments. The experimental results show that the performance of the normalized 3D face recognition method is superior to that of an un-normalized 3D face recognition method for overcoming the problems of pose variation.

3차원 운동 입력장치 구현 (Experiment of a 3D Motion Input Device)

  • 이우원;최명환
    • 산업기술연구
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    • 제19권
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    • pp.173-178
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    • 1999
  • In many areas of technology there are machines and systems controllable in up to six degrees of freedom. Helicopters and underwater vehicles, industrial robots are among the first representatives of this category. They need six degrees of freedom in order to move and orient within their workspace. An even broader and more explosively growing area is 3D computer graphics and virtual environment. In this work, functions of 3D input device are described and two types of commercial 3D input device are presented. Then, a preliminary experiment of a low cost 6 axis force/moment sensor is presented that can also be sued as a 3D input device. A low cost force/moment sensor and its application in robot teaching experiment is described. It computes the direction of 3 components of the force and 3 components of the moment applied by human holding the sensor by hand. The concept is shown by an experiment where the tool position and orientation of a robot in 3 dimensional space is controlled by the proposed sensor.

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