• Clinical and Experimental Pediatrics
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• v.46 no.4
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• pp.400-403
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• 2003

Congenital adrenal hyperplasia(CAH) is a recognized cause of precocious pseudopuberty. Some children with CAH also develop true precocious puberty with early maturation of the hypothalamic-pituitary-gonadal axis. We review a case of CAH who eventually developed central precocious puberty nine months after initial treatment with corticosteroid. A 3-year-old boy visited complaining of rapid growth, a large penis and frequent penile erections. This patient was diagnosed with CAH with elevated 17-OH progesterone and cortical hypertrophy of adrenal gland on CT scan. His gonadotropin levels were within the normal prepubertal range. Even on treatment with corticosteroid he grew rapidly and had testicular enlargement, pubic hair development and rapid bone maturation. At second admission, his gonadotropin levels were elevated both basally and in response to LHRH stimulation, suggesting that the CAH led to early activation of pubertal gonadotropin secretion(true precocious puberty). He was treated with monthly depot injections of a LHRH analog in addition to the hydrocortisone. His second sexual characteristics regressed gradually and rate of linear growth and bone maturation decreased.

• Tuberculosis and Respiratory Diseases
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• v.40 no.3
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• pp.308-313
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• 1993

Although uncommon, rhabdomyosacomas are one of the most frequent forms of cancer of soft parts, particularly in children under the age of 15. There has been only one case of primary rhabdomyosarcoma arising at the pleura, reprted by Hamada, Japan, 1989, in the world. A case of primary rhabdomyosacoma arising at the pleura is reported. This 15 year-old male patient was admitted to the hospital due to a one-month history of dyspnea on exertion and massive right pleural effusion. Pleural biopsy revealed embryonal rhabdomyosarcoma histologically. Immunohistochemical study shows positive reactivity to desmin, vimentin, and cytokeratin. Ultrastructural demonstration of thin and thick myofilaments was most helpful for confirming the histopathological diagnosis. The patient was received 6 cycles of chemotherapy with adriamycin, cyclophosphamide, vincristine and dacarbazine. The chemotherapy response was fairly good that the patient's symptom was absent and pleural effusion and mass size was improved 6 months after chemotherapy. This paper reports the second case of primary rhabdomyosarcoma of the pleura in the world with the review of literature.

• Childhood Kidney Diseases
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• v.24 no.1
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• pp.42-46
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• 2020

Disturbances in water and salt balances are relatively common in children after brain tumor surgery. However, the coexistence of different diseases of water and sodium homeostasis is challenging to diagnose and treat. The coexistence of combined central diabetes insipidus (CDI) and cerebral salt wasting syndrome (CSWS) is rare and may impede accurate diagnosis. Herein, we report the case of an 18-year-old girl who underwent surgery for a germinoma and who presented prolonged coexistence of CDI and CSWS. The patient was diagnosed with panhypopituitarism with CDI at presentation and was treated with hydrocortisone, levothyroxine, and desmopressin. Postoperatively, she developed polyuria of more than 3L/day, with a maximum daily urine output of 7.2 L/day. Her serum sodium level decreased from 148 to 131 mEq/L. Polyuria was treated with desmopressin at incremental doses, and hyponatremia was managed with fluid replacement. At 2 months after surgery, she presented with hyponatremia-induced seizure. Polyuria and hyponatremia combined with natriuresis indicated CSWS. Treatment with fludrocortisone were initiated; then, her electrolyte level gradually normalized. CSWS is self-limiting and generally resolves within 2 weeks. However, the patient in this study still required treatment with vasopressin and fludrocortisone at 16-months after surgery. Hyponatremia in a patient with CDI may be erroneously interpreted as inadequate CDI control or syndrome of inappropriate antidiuretic hormone secretion, leading to inappropriate treatment. The identification of the potential combination of CDI and CSWS is important for early diagnosis and treatment.

• Asian Pacific Journal of Cancer Prevention
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• v.15 no.17
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• pp.7263-7266
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• 2014

Background: Cervical cancer which is one of the most preventable cancers is an important public health problem worldwide, and especially in developing countries. The aim of this study was to determine knowledge and attitudes about the HPV vaccination of mothers with 0- to 18-year old children. Materials and Methods: Written approval was taken from the local authorities. The study subjects consisted of 799 mothers who agreed to participate. The data were collected via a "Personal Information Form" which included 30 questions that were prepared by the researchers themselves in line with the literature. The data were collected by face to face interviews with the mothers. Analyses were performed using commercial software. Results: The mean age of the mothers who participated in the study was $32.0{\pm}6.52$, and 88.1% reported no information about HPV, and 83.5% no information about HPV vaccination. Only 0.7% of the mothers had daughters who had HPV vaccination, and 44.3% of the mothers who had sons were found out to be indecisive about having HPV vaccination. There was a significant corelation between the educational status of the mothers and their knowledge about HPV vaccination (p<0.05). However, there was no significant correlation in terms of economic conditions (p>0.05). Conclusions: This study suggested that mothers had very little information on HPV and HPV vaccination. Knowledge of the disease and its vaccination is an essential factor for the success of the vaccination program. It is of great importance that mothers are trained in this subject by health professionals.

• Clinical and Experimental Pediatrics
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• v.51 no.8
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• pp.886-891
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• 2008

Mixed connective tissue disease (MCTD) is characterized by diverse symptoms including rheumatoid arthritis, scleroderma, systemic lupus erythematosus, and dermatomyositis, associated with high titers of antibodies to extractable nuclear antigen (ENA), especially anti-ribonucleoprotein (anti-RNP) antibody. Since the first report of 25 cases with MCTD in adults, there have been only a few cases of MCTD reported in children. Here, we report a rare childhood case of MCTD in a 7-year-old girl presenting initially with Raynaud's phenomenon, swollen hands, and ulceration of the right index finger tip followed by alopecia and arthritis during follow-up.

• Clinical and Experimental Pediatrics
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• v.51 no.11
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• pp.1222-1227
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• 2008

Restless legs syndrome (RLS) is a common neurological sleep disorder in adults characterized by the following diagnostic criteria: an urge to move that is usually associated with unpleasant sensations and symptoms that are worse at rest, relieved by movement, and most severe at night. The definite diagnosis of RLS in children is stricter and consists of self-description of leg discomfort or the presence of 2 of 3 supportive criteria combined with 4 essential criteria for diagnosis in adults. RLS in childhood has often been misdiagnosed as growing pains or a part of normal development. As a result, physicians have often missed the chance for proper management. We diagnosed a case of RLS in a 5-year-old boy presenting with growing pains, whose mother was found to have had RLS since childhood. We confirmed RLS by using a polysomnograph, in which the indices of periodic limb movement syndrome (PLMS) and periodic limb movement during wakefulness (PLMW) were recorded to be compatible with RLS criteria. The patient's ferritin level was low normal, and his symptoms improved after taking iron supplements.

• Journal of the Korea Furniture Society
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• v.27 no.3
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• pp.203-210
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• 2016

According to the research on the gender ratio of furniture design courses at universities, female students account for 70 to 80 percent of the total enrollments. Likewise, other design courses reveal the similar trend. Even though female students want to build up their career in the furniture design or related fields, the figure is not so high. There is a trend that many female designers tend to take time off or quite their jobs after their marriage for that reasons such as pregnancy, childbirth, the upbringing of children and so on. The study also shows that women with higher education feel more difficult to resume their careers after being left from economic activity for a long period; this results in the lower figure of women involved in the specialized jobs than men. In particular, the furniture companies avoid hiring old female designers because they believe that younger candidates are more capable of learning the latest style; therefore, it has become harder for the job seeks to win the competition in the job market. The data released by Statistics Korea in 2015 shows that there was the higher increase in female employees than the figure of the male workers, compared to the previous year. As it can be seen, female workforce was emerged as the new growth power; Nevertheless, the working environment and conditions haven't meet the demands from women despite the gradual rise of female job seekers inspired by their wish to achieve self-realization, gender equality. To conclude, this is to suggest the plans for the foundation and management of small-scale carpentry studios so that women, who have a degree in furniture design studies and wish to resume their careers after their long breaks, start their own carpentry studios so as to reach self-realization and feel satisfied with their work while earning their livelihoods.

• Pediatric Infection and Vaccine
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• v.27 no.1
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• pp.62-68
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• 2020

Acute bacterial sinusitis is one of the most common diseases in children, and 5-13% of patients with viral upper respiratory infection experience secondary bacterial sinusitis as a complication. Isolated sphenoid sinusitis is rarer than frontal, maxillary, and ethmoid sinusitis. However, it presents potentially devastating complications, such as cranial nerve involvement, brain abscess, and meningitis, owing to its anatomical location. Nontypeable Haemophilus influenzae (NTHi) commonly causes acute bacterial sinusitis but rarely causes bacteremia, particularly in immunocompetent patients. We present a rare case of a 14-year-old boy with bacteremia due to isolated sphenoid sinusitis caused by NTHi.

• Journal of Families and Better Life
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• v.31 no.2
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• pp.25-39
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• 2013

The main purpose of this study was to examine the relationship among co-parenting, maternal parenting stress, and preschoolers' anxiety and hyperactivity with a sample of 155 mothers with 3 to 4 year old children (83 boys and 72 girls) living in Seoul. They completed a questionnaire on co-parenting, maternal parenting stress, and preschoolers' anxiety and hyperactivity. The results were analyzed by means of correlations and regressions. Co-parenting was positively correlated with preschoolers' anxiety and hyperactivity but affectionate, integrated co-parenting was negatively correlated with preschoolers' anxiety and hyperactivity. Maternal stress of parental suffering, dysfunctional interaction, and difficult temperament were positively related to preschoolers' anxiety and hyperactivity. Conflicting co-parenting was positively correlated with maternal stress of parental suffering, but affectionate and integrated co-parenting was negatively correlated with maternal stress of parental suffering and difficult temperament. Furthermore, maternal parenting stress mediated the relationship between co-parenting and preschoolers' anxiety and hyperactivity. Especially, maternal stress of parental suffering tended to play a perfectly mediating role between conflicting and integrated co-parenting and preschoolers' anxiety, between conflicting co-parenting and preschoolers' hyperactivity. Maternal stress of difficult temperament tended to play a perfectly mediating role between integrated co-parenting and preschoolers' anxiety and between conflicting co-parenting and preschoolers' hyperactivity. These results clearly indicate that maternal parenting stress plays a crucial role in the levels of preschoolers' anxiety and hyperactivity.

• Tuberculosis and Respiratory Diseases
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• v.47 no.6
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• pp.857-862
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• 1999

In contrast to juvenile laryngeal papillomatosis, which occurs most often in children and teenagers and is usually self limited, soliatry papillomas in adults are one of uncommon tumors of airway, and have a higher incidence of cancer. They are caused by the respiratory infection of human papilloma virus(HPV). They could spread to more distal airways and have a tendency of recurrence after limited surgical excision. Recently endoscopic therapies such as Nd-YAG laser, electrocautery, and cryotherapy provide extremely effective treatment modalities. We report a case of solitary tracheal papillomas in a 48 year-old man who presented with cough, scanty hemoptysis, and functional evidence of central airway obstruction. He was successfully treated by a Nd-YAG laser therapy via fiberoptic bronchoscopy under the local anesthesia.