• Title/Summary/Keyword: 3-biphenylisoquinolin-1-ones

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Structure-Activity Relationship Studies of Isoquinolinone Type Anticancer Agent

  • Cheon, Seung-Hoon;Park, Joon-Suck;Lee, Joon-Yeol;Lee, You-Na;Yi, Hyo;Lee, Chong-Ock
    • Archives of Pharmacal Research
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    • v.24 no.4
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    • pp.276-280
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    • 2001
  • Substituted isoquinolin-1-ones (1) were synthesized to test their in vitro anticancer activity. 3-Biphenyl-H-methylisoquinolin-1-one (7) showed the most potent anticancer activity against five different human cancer cell lines.

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