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Accuracy of Frozen Sections for Intraoperative Diagnosis of Complex Atypical Endometrial Hyperplasia

  • Turan, Taner;Karadag, Burak;Karabuk, Emine;Tulunay, Gokhan;Ozgul, Nejat;Gultekin, Murat;Boran, Nurettin;Isikdogan, Zuhal;Kose, Mehmet Faruk
    • Asian Pacific Journal of Cancer Prevention
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    • v.13 no.5
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    • pp.1953-1956
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    • 2012
  • Objective: The purpose of this study was to correlate the histological diagnosis made during intraoperative frozen section (FS) examination of hysterectomy samples with complex atypical endometrial hyperplasia (CAEH) diagnosed with definitive paraffin block histology. Methods: FS pathology results of 125 patients with a preoperative biopsy showing CAEH were compared retrospectively with paraffin block pathology findings. Results: Paraffin block results were consistent with FS in 78 of 125 patients (62.4%). The FS sensitivity and specificity of detecting cancer were 81.1% and 97.9%, with negative and positive predictive values of 76.7%, and 98.4%, respectively. Paraffin block results were reported as endometrial cancer in 77 of 125 (61.6%) patients. Final pathology was endometrial cancer in 45.3% patients diagnosed at our center and 76.9% for patients who had their diagnosis at other clinics (p=0.018). Paraffin block results were consistent with FS in 62.4% of all cases Consistence was 98.4% in patients who had endometrial cancer in FS. Conclusion: FS does not exclude the possibility of endometrial cancer in patients with the preoperative diagnosis of CAEH. In addition, sufficient endometrial sampling is important for an accurate diagnosis.

Evaluation of Enterotoxigenic Bacteroides fragilis from Colonic Washings from Patients Undergoing Colonoscopy

  • Van, Ni;Ahlberg, Ned;Jung, Byung Chul;Lee, Min Ho;Ahn, Seung Ju;Lee, In-Soo;Kim, Yoon Suk;Rhee, Ki-Jong
    • Biomedical Science Letters
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    • v.18 no.4
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    • pp.362-368
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    • 2012
  • Enterotoxigenic Bacteroides fragilis (ETBF) is an intestinal commensal bacterium implicated as a risk factor for colon cancer. The key virulence factor is a secreted toxin called B. fragilis toxin (BFT). In this study we used an in vitro bioassay to examine the prevalence of ETBF in colonic washings from patients with colorectal polyps and normal control patients. We found that 9.3% of polyp patients and 10.9% of non-polyp patients harbored ETBF, respectively. A total of nine ETBF clinical isolates were isolated and confirmed to be positive for the BFT gene by PCR analysis and the ability to induce IL-8 secretion in the colonic epithelial cell line HT29/c1. Two of the ETBF clinical strains were characterized further in vitro and in vivo. We found that the two ETBF clinical isolates induced E-cadherin cleavage in HT29/c1 cells and promoted colonic inflammation in C57BL/6 mice. Our results indicate that the prevalence of ETBF in polyp patients were similar in non-polyp patients suggesting that ETBF carriage does not positively correlate to polyp incidence.

Response od Striped Puffer to the White Light (백색광에 대한 까치복의 반응)

  • 양용림
    • Journal of the Korean Society of Fisheries and Ocean Technology
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    • v.24 no.4
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    • pp.144-149
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    • 1988
  • The purpose of this study is to find the light intensity which induced maximum gathering rate and to observe the variation of the gathering rate both in daytime and tat night by using Striped puffer, Fugu xanthopterus (Temminck et Schlegel). An experimental tank(360L$\times$50W$\times$55H cm) was set up in a dark room. An illumination system was attached to the end of one side of the tank to control horizontal light intensity. Eight artificial light sources were prepared by combination of three light bulbs (10W, 60W, 100W) and eight filters. During the experiment water depth was maintained 50 cm level in the tank. The tank was marked into six longitudinal sections each being 60cm long to observe the distribution of fish. The fish were acclimatized in dark condition for 50 minutes prior to the main experiment. Upon turning on the light, the number of fish in each section was counted 60 times every 30 seconds, and the gathering rate was obtained from the average number of fish in each section. The light intensity inducing maximum gathering rate was 298.56 lux (188.44-444.96 lux) at daytime and 298.56 lux (188.44-444.96 lux) at night. The variation of the gathering rate of fish in illumination time was increasing trend fluctuately and did not show any distinctive difference between day and night.

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Accessibility Analysis of Mobile Applications for Open Platforms (개방 플랫폼용 모바일 애플리케이션 접근성 분석)

  • Moon, Hyun Ju;Min, Hong Ki;Kim, Sukil
    • Journal of rehabilitation welfare engineering & assistive technology
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    • v.11 no.2
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    • pp.187-198
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    • 2017
  • In this study, we analyzed the accessibility of open platform Android mobile banking applications, based on Korean mobile application accessibility KS standard, Section 508 technical standard of Rehabilitation Act, and European BBC guidelines. Experimental result showed that there are no mobile banking applications of 8 commercial banks in Korea that satisfy all guidelines of three standards. Typical violations included missing alternative text, keyboard focus violations, control size and spacing non-compliance, and low contrast ratio. These violations are fatal in that they make the accessibility of the blind, the disabled and the low vision and the elderly impossible. The reason that mobile banking applications do not comply with accessibility is that mobile application developers and providers have low awareness of accessibility and do not know how to implement accessibility properly. Comparing Korea mobile application accessibility guidelines with the revised standard of the Section 508 of Rehabilitation Act and the BBC standard, many guidelines are missing. Also, evaluation criteria are ambiguous and abstract, making it difficult for developers to refer specifically. Therefore, improving mobile application accessibility requires developer and government efforts and complementation of standards.

Response of Marbled Sole to the White Lights (백색광에 대한 문치가자미의 반응)

  • YANG Yong-Rhim
    • Korean Journal of Fisheries and Aquatic Sciences
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    • v.19 no.6
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    • pp.558-562
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    • 1986
  • The purpose of this study is to find the light intensity which induces maximum gathering rate and to observe the variation of the gathering rate both in daytime and at night by using marbled sole, Limanda yokohamae (Gunther). An experimental tank ($360L{\times}50W{\times}55H\;cm$) was set up in a dark room. An illumination system was attached to the end of one side of the tank to control horizontal light intensity. Six artificial light sources were prepared by combination of two light bulbs (5W, 150W) and seven filters. During the experiment water depth was maintained 50 cm level in the tank. The tank was marked into six longitudinal sections each being 60 cm long to observe the distribution of fish. The fish were acclimatized in dark condition for 50 minutes prior to the main experiment. Upon turning on the light, the number of fish in each section was counted 40 times every 30 seconds, and the gathering rate was obtained from the average number of fish in each section. The light intensity inducing maximum gathering rate was 1.9 lux ($1.2{\sim}2.9\;lux$) in the daytime and 0.7 lux ($0.5{\sim}1.1\;lux$) at night. The variation of the gathering rate of fish in illumination time was small and comparatively fluctuated with stability.

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Electrochemical Properties of Activated Carbon Supecapacitor Containing Sulfonated Polypropylene Separator Coated with a Hydrogel Polymer Electrolyte (하이드로겔 고분자 전해질이 코팅된 술폰화 폴리프로필렌 격리막을 포함하는 활성탄 수퍼커패시터 특성)

  • Yoon, Choong Sub;Ko, Jang Myoun;Latifatu, Mohammed;Lee, Hae Soo;Lee, Young-Gi;Kim, Kwang Man;Won, Jung Ha;Jo, Jeongdai;Jang, Yunseok;Kim, Jong Huy
    • Korean Chemical Engineering Research
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    • v.52 no.5
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    • pp.553-557
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    • 2014
  • Sulfonated polypropylene (S-PP) is prepared by sulfuric acid-acetone aldol condensation reaction of polypropylene (PP) separator to yield hydrophilic separator surface with a moderate amount of $-SO_3H$ groups. Activated carbon supercapacitor is also fabricated adopting the S-PP separator coated with potassium polyacrylate (PAAK) hydrogel polymer electrolyte. As a result, the hydrophilic surface of S-PP separator involves better physical and electrochemical properties such as decrease in contact angle, improvements of wettability, electrolyte uptake, and ionic conductivity to give higher specific capacitance and long cycle-life.

Preparation of Solid Polymer Electrolytes by Ultraviolet Radiation and the Electrochemical Properties of Activated Carbon Supercapacitor Adopting Them (자외선 조사에 의한 고체 고분자 전해질의 제조와 이를 채용한 활성탄 수퍼커패시터의 전기화학적 특성)

  • Won, Jung Ha;Kim, Yong Joo;Lee, Young-Gi;Kim, Kwang Man;Kim, Jong Huy;Ko, Jang Myoun
    • Journal of the Korean Electrochemical Society
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    • v.16 no.2
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    • pp.91-97
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    • 2013
  • Solid polymer electrolyte films are prepared by ultraviolet radiation in the mixtures of an ionic liquid salt (1-ethyl-3-methylimidazolium tetrafluoroborate, $EMIBF_4$) and solvent (acetonitrile (ACN) or propylene carbonate(PC)), and an oligomer (poly(ethylene glycol)diacrylate, PEGDA, 45-60 wt.%). Electrochemical properties of activated carbon supercapacitors adopting the solid polymer electrolyte films as a separator are also examined by cyclic voltammetry and impedance measurement techniques. As a result, the supercapacitor adopting the PEGDA as much as 45 wt.% exhibits a superior capacitance of $46Fg^{-1}$ at $20mVs^{-1}$. It seems that this is due to fast kinetics of ion conduction by sufficient film flexibility, which can be allowed by comparatively weak ultraviolet curing of small anount of the PEGDA.

Effect of Rootzone Mixes Amended with Crumb Rubber on the Physical Properties (폐 타이어 고무칩을 혼합한 개량제의 물리성 개선 효과)

  • Chong, She-Kong;Ok, Chang-Ho
    • Asian Journal of Turfgrass Science
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    • v.20 no.1
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    • pp.83-91
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    • 2006
  • This research was initiated to enhance the tilth of fine-textured soil for turf growth by incorporation of crumb rubber shredded from used tires. A specific objective was to determine the physical properties of soil mixes amended with different grade and amount of crumb rubber in soils. Two soils and three different grades(3.5, 6.5 and 9.5 mm) of crumb rubber were used. The soils selected were an Arenzville silt loam(coarse-silty, mixed, nonacid, mesic Typic Udifluvents) and a Hosmer silty clay loam(fine-silty, mixed, mesic Typic Fragiudalfs). The amount of crumb rubber mixed in soil ranged from 0 to 0.4 $g{\cdot}g^{-1}$(using 0.05 $g{\cdot}g^{-1}$) increments and 0 as a control. For each treatment, soil cores were constructed following the recommendation by the United States Golf Association Green Section Record. Results indicated that porosity of the mixes decreased as the amount of crumb rubber increased. Regardless of the grade of crumb rubber, mixes with less than 0.15 $g{\cdot}g^{-1}$ of crumb rubber in fine-textured soil could not enhance their macro-porosity and hydraulic conductivity. However, as the amendment increased over 0.15 $g{\cdot}g^{-1}$, the tilth of the mixes had improved significantly macro-porosity, hydraulic conductivity and air permeability, as compared with a control.

Separator Properties of Silk-Woven Fabrics Coated with PVdF-HFP and Silica and the Charge-Discharge Characteristics of Lithium-ion Batteries Adopting Them (PVdF-HFP와 실리카가 코팅된 실크 견직물의 분리막 특성과 이를 채용한 리튬이온전지의 충방전 특성)

  • Oh, Seem Geon;Lee, Young-Gi;Kim, Kwang Man;Lee, Yong Min;Kim, Sang Hern;Kim, Yong Joo;Ko, Jang Myoun
    • Korean Chemical Engineering Research
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    • v.51 no.3
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    • pp.330-334
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    • 2013
  • Mixtures of poly(vinylidene fluoride-co-hexafluoropropylene) (PVdF-HFP) and silica nanoparticles are coated on the surface of a silk fabrics separator. The coated separators are finally prepared by injecting an electrolyte solution and then characterized for use of lithium-ion battery separator/electrolyte. In the preparation, various contents of dibutylphthalate (DBP) as a plasticizer are used to enhance the formation of micropores within the coated membrane. The coated silk fabrics separators are characterized in terms of ionic conductivity, drenching rate, and electrochemical stability, and the charge-discharge profiles of lithium-ion batteries adopting the coated separators are also examined. As a result, the coated silk fabrics separator prepared using DBP 40~50 wt% and silica shows the superior separator properties and high-rate capability. This is due to (i) high sustainability of silk fabrics, (ii) the formation of micropores with the coated layer membrane by DBP, (iii) increase in drenching rate by silica nanoparticles to involve great enhancements in specific surface area and ionic conductivity.

A Study on the Web Mapping Method and Application of the Topographic Information in an Open Environment (개방환경에서 지형정보의 웹지도화 방법과 적용에 관한 연구)

  • Kim, Nam-Shin
    • Journal of the Korean association of regional geographers
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    • v.13 no.5
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    • pp.563-575
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    • 2007
  • This study aims to investigate a possibility of using topographic information by web mapping in open environments. Web mapping intends to focus on a map analysis and application of the function and geo-visualization. Functions of Web topographic info-map include a spatial analysis, enlargement and minimization, movement, landuse information, user-controling 3 dimension map, landform cross-section analysis, shortest path analysis. The web system adopts SVG(scalable vector graphics), MYSQL, PHP, XML for mapping. SVG has open source policy, so everyone can use it, as well, it is effective on flexible database linkage, cartographic representation. 3D map is intended to represent 3D map by user-controlled sunshine putting pixel opacity by elevation values after making DEM. Landform is designed to show a cross-section analysis and statistics by retrieving height information from database engine with clicking two points on the map. Shortest path analysis within regions uses Dijkstra's algorithm. Near future, resultantly, the area of WebGIS will have to meet more social demands for use-created geo-information and application, so more researches are needed to be web mapping more applicable for users.

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