• Journal of Korea Multimedia Society
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• v.9 no.7
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• pp.808-817
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• 2006

Although the generally used the velocity index of doppler effect is a very significant factor in the functional evaluation of the left ventricle, it depends on the subjective evaluation of an inspector. The objective data of the motility can be obtained from the gated myocardial SPECT images by quantitative analysis. However, it is difficult to image visual of the velocity of the motion. The aim of our study is to develop a new method for the imaging velocity using the gated myocardial SPECT images and use it as an evaluation index for analyzing motility. First we visualized left ventricle into 3 dimensions using the coordinates of the points which were obtained through a segmentation of myocardium. Each point was represented by the different colors, according to the velocity of each point. We performed a validation study using 7 normal subjects and 15 myocardial infarction patients. To analyze motility, we used the average of the moved distance and the velocity. In normal cases, the average of the moved distance was 4.3mm and the average of the velocity was 11.9mm. In patient cases, the average of the moved distance was 3.9mm and the average of the velocity was 10.5mm. These results show that the motility of normal subjects is higher than the abnormal subjects. We expect that our proposed method could become a way to improve the accuracy and reproducibility for the functional evaluation of myocardial wall.

• Journal of the Institute of Electronics Engineers of Korea SD
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• v.48 no.7
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• pp.37-47
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• 2011

Real picture like high quality computer graphic is widely used in various fields and shader processor, a key part of a graphic processor, has been advanced to programmable unified shader. However, The existing graphic processors have been optimized to commercial algorithms, so development of an algorithm which is not based on it requires an independent shader processor. In this paper, we have designed and implemented a control unit to support high quality 3 dimensional computer graphic image on programmable integrated shader processor. We have done evaluation through functional level simulation of designed control unit. Hardware resource usage rate are measured by implementing directly on FPGA Virtex-4 and execution speed are verified by applying ASIC library. the result of an evaluation shows that the control unit has the commands more about 1.5 times compared to the other shader processors that is a behavior similar to the control unit and with a number of processing units used in a shader processor, compared with the other processors, overall performance of the control unit is improved about 3.1 GFLOPS.

• Journal of the Korea Institute of Building Construction
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• v.22 no.4
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• pp.347-358
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• 2022

In order to satisfy the extraction and use of information such as estimates and processes required in the design and construction stages of BIM, which is an expectation of overall construction operation for the design and construction stage of domestic buildings, it is insufficient to supply and apply mobile technologies or terminals. In this paper, standardization of BIM-based processes from the design stage to the construction stage is proposed as an efficient construction system method through mobile-based simulation and test-bed case analysis review. The current status and potential of BIM application were identified through theoretical review of BIM and case studies at home and abroad. In addition, the overall flow of the project and the direction of effective process construction were investigated through each process by 3D, 4D, and 5D execution stage and the role of each collaborator. 4D building process BIM simulation system using mobile was implemented by applying a visualization engine that simulates process information, object information connection module, and related object information. Therefore, it was possible to minimize the possibility of re-construction of the BIM design and construction process model through the visualization of 2D drawings based on the 3D model of the building and the review of errors and interferences in the drawings. In addition, in the implementation of simulation for each process of the construction process through mobile devices, it was possible to support construction progress and process management according to the optimal option selected by the user.

• Polymer(Korea)
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• v.30 no.1
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• pp.14-21
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• 2006

Tissue engineering techniques require the use of a porous biodegradable/bioresorbable scaffold, which server as a three-dimensional template for initial cell attachment and subsequent tissue formation in both in vitro and in vivo. Small intestinal submucosa (SIS) has been investigated as a source of collagenous tissue with the potential to be used as biomaterials because of its inherent strength and biocompatibility. SIS-loaded poly(L-lactide-co-glicolide)(PLGA) scaffolds were prepared by solvent casting/particle leaching. Characterizations of SIS/PLGA scaffold were carried out by SEM, mercury porosimeter, and so on. Muscle-derived stem cells can be differentiated in culture into osteoblasts, chondrocytes, and even myoblasts by the controlling the culture environment. Cellular viability and proliferation were assayed by 3-(4,5-dimethylthiazole-2-yl)-2,5-diphenyltetrazolium-bromide(MTT) test. Osteogenic differential cells were analyzed by alkaline phosphatase(ALP) activity. SIS/PLGA scaffolds were implanted into the back of athymic nude mouse to observe the effect of SIS on the osteoinduction compared with controlled PLGA scaffolds. Thin sections were cut from paraffin embedded tissues and histological sections were conducted hematoxylin and eosin (H&E), Trichrome, and von Kossa. We observed that bone formatioin of SIS/PLGA hybrid scaffold as natural/synthetic scaffold was better thean that of only PLGA scaffold. It canb be explained that SIS contains various kinds of bioactive molecules for osteoinduction.

• The Journal of Korean Society for Radiation Therapy
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• v.19 no.1
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• pp.27-33
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• 2007

Purpose: We have performed SRS (stereotactic radiosurgery) for avm (arterry vein malformation) and brain cancer. In order to verify dose and localization of SRS, dose distributions from TPS ($X-Knife^{(R)}$ 3.0, Radionics, USA) and GafChromic $EBT^{(R)}$ film in a head phantom were compared. Materials and Methods: In this study, head and neck region of conventional humanoid phantom was modified by substituting one of 2.5 cm slap with five 0.5 cm acrylic plates to stack the GafChromic $EBT^{(R)}$ film slice by slice with 5 mm intervals. Four films and five acrylic plates were cut along the contour of head phantom in axial plane. The head phantom was fixed with SRS head ring and adapted SRS localizer as same as real SRS procedure. CT images of the head phantom were acquired in 5 mm slice intervals as film interval. Five arc 6 MV photon beams using the SRS cone with 2 cm diameter were delivered 300 cGy to the target in the phantom. Ten small pieces of the film were exposed to 0, 50, 100, 200, 300, 400, 500, 600, 700, 800, 900 cGy, respectively to calibrate the GafChromic $EBT^{(R)}$ film. The films in the phantom were digitized after 24 hours and its linearity was calibrated. The pixel values of the film were converted to the dose and compared with the dose distribution from the TPS calculation. Results: Calibration curve for the GafChromic $EBT^{(R)}$ film was linear up to 900 cGy. The R2 value was better than 0.992. Discrepancy between calculated from $X-Knife^{(R)}$ 3.0 and measured dose distributions with the film was less than 5% through all slices. Conclusion: It was possible to evaluate every slice of humanoid phantom by stacking the GafChromic EBT film which is suitable for 2 dimensional dosimetry, It was found that film dosimetry using the GafChromic $EBT^{(R)}$ film is feasible for routine dosimetric QA of stereotactic radiosurgery.

• The Korean Journal of Pesticide Science
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• v.9 no.2
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• pp.140-145
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• 2005

Quantitative Structure Activity Relationship (QSAR) assumes the relatedness between physical property and biological activity. However, activity data measured at single concentration such as percent activity have not been used extensively for modeling purpose. This probably comes from the fact that these values are qualitative instead of quantitative. To utilize percent activity data for molecular modeling, we classified the whole data into two classes. One class represents the active while the other signifies the inactive. The percent activity data of ${\beta}$-Ketoacetoanilides measured for TLB (Tomato Late Blight) were investigated. CoMFA (Comparative Molecular Field Analysis) was used as a discriminant function. Using CoMFA provides 3D (three dimensional) information, which is crucial for chemical insight. It can also serve as a predictive model. The resultant model classified the given data correctly (98%). When LOO (leave-one-out) crossvalidation procedure was applied, the classification accuracy was 69%. Therefore two class approximation of percent activity data with CoMFA can be utilized to understand the relationship between chemical structure and biological activity and design subsequent chemical analogs.

• Proceedings of the Korea Water Resources Association Conference
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• 2011.05a
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• pp.420-420
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• 2011

도시지역의 내수침수피해는 거의 매년 발생하고 있으며, 반지하와 같은 거주공간이 매우 취약한 상태이다. 특히 최근에는 지하철, 지하상가 등이 대규모 개발되고 복합네트워크화 되어 지하공간의 침수대책과 대피방안 마련이 시급한 상황이다. 일본의 경우 2000년 토카이 호우피해 후 통합유출해석 모형을 개발하였으며, 1999년 및 2003년 후쿠오카 침수피해 발생 후 특정도시하천침수피해대책법을 제정, 1999 후쿠오카, 2004년 하마마츠, 2008년 카누마 피해 후 일본 방재연구소에서는 실시간 1차원 지표범람모형과 모니터링을 통한 실시간 내수침수지도를 개발하였다. 특히 지하공간에 대해서는 "지하공간에 유입하는 범람수가 계단상 보행자게에 주는 위험성에 관한 연구" 등 실험을 바탕으로 각종 지하공간 침수대책 매뉴얼 및 지하시설의 침수시 피난확보계획 지침, 지하공간 침수대책 가이드라인 등 인명피해를 줄이고자하는 노력이 계속되어 오고 있다. 우리나라는 2006년 경기도 고양시 3호선 정발산역이 침수되었으며, 2010년 서울시 지하철 2호선 사당역 및 4호선이 침수되는 등의 지하철 침수피해와 2010년 서울시 광화문 지하상가, 인천시 부평구 우림라이온스 벨리, 우남플라자, 계양구 농협하나로마트, 서원아파트 등의 지하상가와 지하다층의 침수피해가 발생하였다. 특히 2006년 3호선 정발산역 침수는 17시간이나 지하철이 불통되었고 이로 인하여 심각한 교통 체증이 유발 되었다. 본 연구에서는 2010년 집중호우로 인한 서울, 인천지역의 지하공간 침수피해를 중심으로 최근 10년간 지하공간 침수피해사례로부터 대표적인 침수피해 원인 및 특성을 정리하였으며, 그 결과 지하공간 침수의 주요원인은 지상공간의 침수류가 지하공간으로 유입하고, 지하공간의 배수설비 용량부족, 지하공간으로의 유입을 방지하기위한 방지턱, 차수판, 침수시 비상전원 공급, 침수시 지하공간 대피 매뉴얼의 부재 등 다양한 원인이 있는 것으로 나타났다. 특히, 소방방재청에서 고시한 '지하공간 침수방지를 위한 수방기준'에 지하공간 침수 방지를 위한 각종 시설의 설치 및 대피 경로지정 등에 대한 기준이 마련되어 있으나, 지하공간 중 유동인구가 가장 많은 지하철역에서 조차 침수에 대한 행동매뉴얼이나 대피에 대한 가이드라인이 마련되지 않은 것으로 나타났다. 따라서, 지하공간 침수를 방지하기 위하여 센서를 이용한 자동 차수판과 경보기 설치, 지하공간의 사람들이 안전한 대피로를 찾을 수 있도록 지상공간 및 지하공간 출입구를 모니터링 할 수 있는 CCTV의 설치, Dry Area를 두어 비상대피 할 수 있는 공간의 마련 등 시설적인 부분에 대하여 '지하공간 침수방지를 위한 수방기준'을 더욱 강화할 필요가 있으며, 지상공간의 침수 상황을 고려한 지하공간의 대피매뉴얼 또는 가이드라인 등의 수립이 필요하다. 또한 이와 더불어 재산 및 인명피해를 더욱 효율적으로 줄일 수 있도록 실시간 예 경보를 위한 침수해석 모형의 개발이 시급하다.

• The KIPS Transactions:PartA
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• v.11A no.7 s.91
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• pp.555-562
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• 2004

Both global volume reduction and local shape changes of hippocampus within the brain indicate their abnormal neurological states. Hippocampal shape analysis consists of two main steps. First, construct a hippocampal shape representation model ; second, compute a shape similarity from this representation. This paper proposes a novel method for the analysis of hippocampal shape using integrated Octree-based representation, containing meshes, voxels, and skeletons. First of all, we create multi-level meshes by applying the Marching Cube algorithm to the hippocampal region segmented from MR images. This model is converted to intermediate binary voxel representation. And we extract the 3D skeleton from these voxels using the slice-based skeletonization method. Then, in order to acquire multiresolutional shape representation, we store hierarchically the meshes, voxels, skeletons comprised in nodes of the Octree, and we extract the sample meshes using the ray-tracing based mesh sampling technique. Finally, as a similarity measure between the shapes, we compute $L_2$ Norm and Hausdorff distance for each sam-pled mesh pair by shooting the rays fired from the extracted skeleton. As we use a mouse picking interface for analyzing a local shape inter-actively, we provide an interaction and multiresolution based analysis for the local shape changes. In this paper, our experiment shows that our approach is robust to the rotation and the scale, especially effective to discriminate the changes between local shapes of hippocampus and more-over to increase the speed of analysis without degrading accuracy by using a hierarchical level-of-detail approach.

• Journal of the Korean Chemical Society
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• v.50 no.5
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• pp.362-368
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• 2006

SH group modifying chemicals were used to characterize the eight cysteine residues of cabbage PLD. 5,5-dithiobis(2-nitrobenzoate)(DTNB) was used to titrate the SH group of cysteine residues . Based on the optical density at 412nm due to the reduced DTNB, 4 SH groups are found to be present in a native PLD while 8 SH groups in the denatured PLD whose tertiary structure was perturbed by 8M urea. The results imply that among the 8 cysteine residues of PLD, the half(4) are exposed on the surface whereas the other half are present at the interior of the enzyme tertiary structure. The PLD was inactivated by SH modifying reagents such as p-chloromercuribenzoate(PCMB), iodoacetate, iodoacetamide, and N-ethylmaleimide. At the addition of dithiothreitol(DTT) only the PCMB inhibited PLD activity was recovered reversibly. The micro-environment of the exposed SH group of cysteine residues was examined with various disulfide compounds with different functional groups and we found that anionic or neutral disulfides appear to be more effective than the positively charged cystamine for inactivating the PLD activity. The effect of redox state of cysteine residues on the PLD activity was further explored with H2O2. The oxidation of SH groups by H2O2 inhibited the PLD activity more than 70%, which was mostly recovered by DTT. From these results, we could confirm chemically that all the cysteine residues of PLD are present as in their reduced SH forms and the 4 SH groups exposed on the surface of the enzyme may play important roles in the regulation of PLD activity.

• Proceedings of the Korea Multimedia Society Conference
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• 2000.11a
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• pp.66-69
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• 2000

웹이 등장하면서 지금까지 인터넷 상에서 텍스트와 이미지를 이용하여 정보를 표현하고 전달하는 방법이 가장 많이 사용되어왔다. 그러나 웹 관련 기술의 비약적인 발달과 네트워크 속도의 증가 및 인터넷의 급속한 보급으로 단순한 텍스트와 이미지 중심의 HTML 문서를 이용한 정보의 전달이 아닌 멀티미디어 데이터를 이용한 정보의 표현과 전달이 점차 증대되고 있다. 이에 따라 멀티미디어 데이터를 전송하기 위한 스트리밍 프로토콜도 등장하였다. 최근에는 컴퓨터의 성능 증가 및 네트워크 속도의 증가(초고속 통신 서비스의 보급)에 의해 멀티미디어 데이터의 전송이 가능하게 됨으로써 기존의 공중파나 CATV 방송국의 형태 지니고 인터넷 상에서 실시간 생방송 서비스와 VOD(Video On Demand) 서비스를 제공하는 인터넷 방송국이 급속하게 생겨나고 있다. (11) 인터넷 방송은 동영상과 오디오의 실시간 전달을 가능하게 하는 멀티미디어 스트리밍 기술과 멀티미디어를 실시 간으로 전송할 수 있는 실시간 전송 프로토콜을 기반으로 발전하고 있다. 인터넷 상에서 멀티미디어 스트리밍 서비스를 하는 대부분의 인터넷 방송은 스트리밍 서버로서 RealNetworks사의 RealSystem과 Microsoft사의 WMT(Windows Media Technologies)를 사용하고 있다. 본 논문은 Real Server와 WMT의 비교 분석을 통해 실시간 전송 프로토콜을 지원하고, 멀티미디어 스트리밍 기술을 지원하는 자바를 기반으로 한 분산 서버 구조의 스트리밍 서버, 서버간의 부하를 제어하는 미들웨어, 멀티미디어 스트림을 재생할 수 있는 클라이언트를 설계하고 구현한다.있다.구현한다. 이렇게 구현된 시스템은 전자 상거래, 가상 쇼핑몰, 가상 전시화, 또는 3차원 게임이나 가상교육 시스템과 같은 웹기반 응용프로그램에 사용될 수 있다.물을 보존·관리하는 것이 필요하다. 이는 도서관의 기능만으로는 감당하기 어렵기 때문에 대학정보화의 센터로서의 도서관과 공공기록물 전문 담당자로서의 대학아카이브즈가 함께 하여 대학의 공식적인 직무 관련 업무를 원활하게 지원하고, 그럼으로써 양 기관의 위상을 높이는 상승효과를 낼 수 있다.하여는, 인쇄된 일차적 정보자료의 검색방법등을 개선하고, 나아가서는 법령과 판례정보를 위한 효율적인 시스템을 구축하며, 뿐만 아니라 이용자의 요구에 충분히 대처할 수 잇는 도서관으로 변화되는 것이다. 이와 함께 가장 중요한 것은 법과대학과 사법연수원에서 법학 연구방법에 관한 강좌를 개설하여 각종 법률정보원의 활용 내지 도서관 이용방법에 관하여 교육하는 것이다.글을 연구하고, 그 결과에 의존하여서 우리의 실제의 생활에 사용하는 $\boxDr$한국어사전$\boxUl$등을 만드는 과정에서, 어떤 의미에서 실험되었다고 말할 수가 있는 언어과학의 연구의 결과에 의존하여서 수행되는 철학적인 작업이다. 여기에서는 하나의 철학적인 연구의 시작으로 받아들여지는 이 의미분석의 문제를 반성하여 본다. 것이 필요하다고 사료된다.크기에 의존하며, 또한 이러한 영향은 $(Ti_{1-x}AI_{x})N$ 피막에 존재하는 AI의 함량이 높고, 초기에 증착된 막의 업자 크기가 작을 수록 클 것으로 여겨진다. 그리고 환경의 의미의 차이에 따라 경관의 미학적 평가가 달라진 것으로