• Journal of international Conference on Electrical Machines and Systems
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• v.1 no.3
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• pp.282-288
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• 2012

A special pulsed electromagnetic actuator is presented whose plunger consists of two parts made of carbon steel and permanent magnet, respectively. The actuator exhibits a high holding force and small consumption of energy. The movement of the plunger is controlled by short current pulses. The static characteristics and other operation properties of the device are modeled numerically.

• Transactions on Electrical and Electronic Materials
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• v.8 no.4
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• pp.182-187
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• 2007

The use of the pulsed electro acoustic (PEA) method allowed us to perform the direct observations of spatio-temporal charge distributions in Electric double layer capacitors (EDLCs) based on polarizable nanoporous carbonaceous electrode. The negative charge density became the maximum, about $205C/m^3$ at the region where was near to collector layer in EDLCs for case $V_{DC}=2.5V$, while the positively charged density became the maximum, about $61.1C/m^3$ at the region where it was located around the cathode layer. The performance of the best sample was found to be better in terms of the charge density (Cs) and specific energy ($E_s$) with a maximum value of ${\sim}8.4F/g$ and 26 Wh/kg. The $C_s$ obtained from the PEA method agreed well with that from the energy conversion method. The PEA measurement used here is a very useful method to quantitively investigates the spatio-temporal charge distribution in EDLCs.

• Journal of Magnetics
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• v.16 no.3
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• pp.259-262
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• 2011

Compared to acupuncture, the pulsed magnetic field (PMF) stimulus is a useful tool for treatment of many physical conditions and health maintenance due to its advantages as a noninvasive and nontoxic medical treatment. The purpose of this study was to investigate the effect of PMF stimulus direction at PC9 on the alpha activity of electroencephalogram (EEG) and vascular aging calculated from photoplethysmograph (PPG). It can be concluded that the direction of PMF stimulus affects the increase of alpha activity of EEG and PPG, indicating the vascular stiffness and the sclerosis level of blood vessels weakly relevant to the direction of PMF stimulus.

• Journal of Powder Materials
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• v.11 no.3
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• pp.210-216
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• 2004

The possibility to decrease agglomeration of Cu nano powders and their separation during pulsed wire evaporation (PWE) process was investigated by controlling the working gas system, i.e., the design of the gas path, the type and pressure of the atmospheric gas. As a result, it was possible to choose the optimal design of the gas path providing large specific surface area and high degree of separation of the synthesized Cu nano powders. It was also shown that an Ar+10∼50$N_2$ mixture can be used in production of Cu nano powders, which do not react with nitrogen.

• Korean Journal of Metals and Materials
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• v.50 no.12
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• pp.961-966
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• 2012

Nano-sized Co and $Al_2O_3$ powders were successfully synthesized from $3/4Co_3O_4$ and 2Al by high-energy ball milling. A dense nanocrystalline $2.25Co-Al_2O_3$ composite was consolidated from mechanically synthesized powders by the pulsed current activated sintering (PCAS) method within 2 min. Consolidation was accomplished under the combined effects of a pulsed current and mechanical pressure. A dense $2.25Co-Al_2O_3$ with relative density of up to 95% was produced under simultaneous application of a 80 MPa pressure and a pulsed current of 2800 A. The fracture toughness and hardness of the $2.25Co-Al_2O_3$ composite were $8MPa{\cdot}m^{1/2}$, $870kg/mm^2$, respectively.

• IMMUNE NETWORK
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• v.5 no.1
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• pp.36-44
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• 2005

Background: The anti-tumor therapeutic effect of autologous tumor cell lysate pulseddendritic cells (DCs) was studied for non-immunogenic and immune suppressive lung cancer model. To test the possibility as an adjuvant therapy, minimal residual disease model was considered in mouse in vivo experiments. Methods: Syngeneic 3LL lung cancer cells were inoculated intravenously into the C57BL/6 mouse. Autologous tumor cell (3LL) or allogeneic leukemia cell (WEHI-3) lysate pulsed-DCs were injected twice in two weeks. Intraperitoneal DC injection was started one day (MRD model) after tumor cell inoculation. Two weeks after the final DC injection, tumor formation in the lung and the tumor-specific systemic immunity were observed. Tumor-specific lymphocyte proliferation and the IFN-${\gamma}$ secretion were analyzed for the immune monitoring. Therapeutic DCs were cultured from the bone marrow myeloid lineage cells with GM-CSF and IL-4 for 7 days and pulsed with tumor cell lysate for 18 hrs. Results: Compared to the saline treated group, tumor formation was suppressed in 3LL tumor cell lysate pulsed-DC treated group, while 3LL-specific immune stimulation was minimum. WEHI-3-specific immune stimulation occurred in WEHI-3 lysate-pulsed DC treated group, which had no correlation with tumor regression. Conclusion: The data suggest the possible anti-tumor effect of cultured DCs as an adjuvant therapy for minimal residual disease state of lung cancer. The significance of immune modulation in DC therapy including the possible involvement of NK cell as well as antigen-specific cytotoxic T cell activity induction was discussed.

• Journal of Korean Physical Therapy Science
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• v.11 no.3
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• pp.5-13
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• 2004

The use of therapeutic ultrasound(US) in humans with malignant neoplasms has been contra-indicated in physical therapy practice. Some studies have shown the results after application of US inhibited of tumor growth but some studies have shown the results facilitated of tumor growth in mouse. The purpose of this study were to determine the effects of US on rectal sarcoma(CT-26) in mouse and to determine the histological change of tumor. Thirty-five female BALB/C mouse, age 6 to 8 weeks received subcutaneous injection of 0.1 105 tumor cells. When tumors grew to 5 mm in diameters, the mouse were randomly assigned to control group(n=7) and high powered continuous US group(n=7) and low powered continuous US group(n=7) and high powered pulsed US group(n=7) and low powered pulsed US group(n=7). The experimental group (four groups) received 10 treatments over a 10-day period of 3 MHz ultrasound. Tumor dimension were measured on days 1(start of treatment), 5(midtreatment), and 10(end of treatment, preexcision and postexcision). Tumors were weighed after excision and the mouse were observated histological change of tumor. All tumors grew larger over time. Mean tumor weights(in grams) and volumes(in cubic millimeters) were 2.063 g and $2729.313\;mm^3$ for the high powered continuous US group 1.881 g and $2428.002\;mm^3$ for the low powered continuous US group 1.730 g and $2381.002\;mm^3$ for the high powered pulsed US 1.673 g and $2289.562\;mm^3$ for the low powered pulsed US group 1.670 g and $2297.333\;mm^3$ for the control group. Ultrasound increased the weight and volume of subcutaneous tumor in mouse. We urge caution in the use of ultrasound in the areas of tumors.

• Electrical & Electronic Materials
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• v.8 no.3
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• pp.285-290
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• 1995

High quality $Y_{1}$Ba$_{2}$Cu$_{3}$$O_{7-x}$ thin films have been fabricated by pulsed Nd:YAG laser deposition using an unusual 'off-axis' target-substrate geometry. Various properties of superconducting $Y_{1}$Ba$_{2}$Cu$_{3}$$O_{7-x}$ thin films have been studied systematically as a function of oxygen pressure during the deposition, in both 'on-axis' and the unusual 'off-axis' target substrate geometries. In the 'off-axis' geometry, one can completely eliminate the so-called 'laser droplets' from the film surface and thus obtain smooth high quality films. It is found that films with optimum structural and electrical properties are obtained at a lower oxygen pressure range during the 'off-axis' deposition when compared with that required in the 'on-axis' deposition geometry.

• IMMUNE NETWORK
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• v.4 no.1
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• pp.44-52
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• 2004

Background: As a potent antigen presenting cell and a powerful inducer of antigen specific immunity, dendritic cells (DCs) are being considered as a promising anti-tumor therapeutic module. The expected therapeutic effect of DCs in renal cell carcinoma was tested in the mouse model. Established late-stage tumor therapeutic (E-T) and minimal residual disease (MRD) model was considered in the in vivo experiments. Methods: Syngeneic renal cell carcinoma cells (RENCA) were inoculated either subcutaneously (E-T) or intravenously (MRD) into the Balb/c mouse. Tumor cell lysate pulsed-DCs were injected twice in two weeks. Intraperitoneal DC injection was started 3 week (E-T model) or one day (MRD model) after tumor cell inoculation. Two weeks after the final DC injection, the tumor growth and the systemic immunity were observed. Therapeutic DCs were cultured from the bone marrow myeloid lineage cells with GM-CSF and IL-4 for 7 days and pulsed with RENCA cell lysate for 18 hrs. Results: Compared to the saline treated group, tumor growth (E-T model) or formation (MRD model) was suppressed in pulsed-DC treated group. RENCA specific lymphocyte proliferation was observed in the RENCA tumor-bearing mice treated with pulsed-DCs. Primary cytotoxic T cell activity against RENCA cells was increased in pulsed-DC treated group. Conclusion: The data suggest the possible anti-tumor effect of cultured DCs in established or minimal residual disease/metastasis state of renal cell carcinoma. Systemic tumor specific immunity including cytotoxic T cell activity was modulated also in pulsed-DC treated group.

• Journal of Oral Medicine and Pain
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• v.22 no.1
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• pp.15-22
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• 1997

In order to investigate the antibacterial effects of pulsed Nd:YAG Laser concerning to Streptococcus mutans, Streptococcus mutans was cultured and standardized and plated in 96 well plates. After that, black dye and chlorhexidine were applied and pulsed Nd:YAG Laser was irradiated to plates. Experimental groups which was applied with black dye and chlorhexidine were divided into 5 groups by concentration. And experimental groups and control group were subdivided as unlased and lased of 20, 40, and 60J. After laser irradiation, All groups were plated in agar plates and incubated for 18 hours. Bacterial colonies were counted and analysed comparitively, and the temperature of culture medium was measured on every laser irradiation. The results were obtained as follows; 1. In case of laser irradiation only, there is no significant reduction in number of Streptococcus mutans by irradiated energy of laser. 2. In case of black dye application, there is no difference by concentration of black dye but there is decrease when applied Laser and black dye simultaneously. 3. When applied chlorhexidine, the number of Streptococcus mutans was decreased according to increase of concentration, but there is no difference by irradiated energy of laser. 4. The temperature of culture medium was increased according to increase of irradiated energy of Laser, and the number of Streptococcus mutans was reduced remarkably just above 50 centigrade and killed above 70 centigrade. As above results, pulsed Nd:YAG Laser has well-absorbing affinity to black dye. And antibacterial effect of pulsed Nd:YAG Laser against Streptococcus mutans is seemed to be due to increase of temperature.