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Safety and Risk Assessment of 3-Monochloro-1,2-propanediol (3-MCPD) (3-Monochloro-1,2-propanediol(3-MCPD)의 안전성 및 위해성 평가)

  • 이병무
    • Toxicological Research
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    • v.18 no.1
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    • pp.1-11
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    • 2002
  • 3-Monochloro-1,2-propanediol(3-MCPD) is currently being a matter of concern because of its toxicity. 3-MCPD produced during the acid hydrolysis of soybean products has been reported to be mutagenic, neurotoxic, nephrotoxic and spermatotoxic. Howerer, the carcinogenicity of 3-MCPD is a controversial issue over the past several decades. 3-MCPD characteristically showed a variety of toxicities in reproductive system such as, decrease in sperm number and sperm motility, infertility, loss of sperm function, and weight decrease in ovary. Due to the toxicity of 3-MCPD, exposure to 3-MCPD has been proposed to be reduced to as low a level as technologically feasible. 3-MCPD can be detected in soy sauce or non-soy sauce products. The legal limit for 3-MCPD this year has been suggested to be 20 ppb($\mu\textrm{g}$/kg)in the European Community. In Korea, the permissible level of 3-MCPD is expected to be 0.3 ppm. In this study, 3-MCPD was toxicologically evaluated in terms of risk assessment in humans.

The Effect of $WO_3$ Addition on Microwave Dielectric Properties in $BaTiO_3-3{(1-x)TiO_2-xWO_3}$ System ($WO_3$ 첨가량 변화에 따른 $BaTiO_3-3{(1-x)TiO_2-xWO_3}$ 계의 고주파 유전특성)

  • 박찬식;변재동;김왕섭;김경용
    • Journal of the Korean Ceramic Society
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    • v.32 no.4
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    • pp.448-454
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    • 1995
  • The effect of WO3 addition on microwave dielectric properties of BaTiO3-3{(1-x)TiO2-xWO3} system was studied. Addition of WO3 to this system resulted in the formation of BaWO4 and Ba2Ti9O20 phases. Both the dielectric constant (K) and the temperature coefficientof resonant frequency (Tf) were decreased with the amount of WO3 addition. The value of Q$\times$f0 was increased as the amount of WO3 was increased up to x=0.0275, and then decreased when x exceeded 0.03. At x=0.0275, this ceramic showed excellent microwave proprties of K=34-35, Q$\times$f0=50,000-53,000, and near zero ppm/$^{\circ}C$ of Tf.

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3D Contents Based Work Process Simulation Development (3D 콘텐츠 기반 작업 프로세스 시뮬레이션 개발)

  • Kim, Gui-Jung;Han, Jung-Soo
    • The Journal of the Korea Contents Association
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    • v.11 no.7
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    • pp.30-37
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    • 2011
  • In this paper we implemented 3D contents based work process simulation for 3D view contents. For this the method of 3D view technique is explained. The automobiles and PC assembly processes according to the virtual scenario showed the technique which assists workers through 3D view. Also for 3D information visualization, max script of contents modeling functions using 3D MAX was developed. The functions are designed to customize coordinate, material edit on modeling, rendering, and 3D object files with max script.

Properties of Multilyer Condensor with Composition Change in the System of Pb(Mg1/3Nb2/3)O3-PbTiO3 (Pb(Mg1/3Nb2/3)O3-PbTiO3계의 조성변화에 의한 다층 콘덴서 물성)

  • 김복희
    • Journal of the Korean Ceramic Society
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    • v.35 no.2
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    • pp.123-128
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    • 1998
  • Multilayer ceramic capacitors(MLCC) were prepared by laminating the layer of composition with dif-ferent Curie temperature to improve temperature coefficient in the Pb(Mg1/3Nb2/3)O3-PbTiO3 binary system. Green sheet was formed by tape casting using Pb(Mg1/3Nb2/3)O3-PbTiO3 and PbTiO3 synthesized with solid state reaction of PBO. Nb2O5 MgO and TiO2. Green sheet with electrode of 70Ag-30Pd was laminated under 300 kg/cm2 at 70$^{\circ}C$ and sintered at 1100$^{\circ}C$ for 2hr. Curie temperatues for MLCC with 10 layers of pure PMN and 0.9PMN-0.1PT were lowered to -22$^{\circ}C$ and 36$^{\circ}C$ respectively. MLCC with 7 layers of PMN and 3 layers of 0.9PMN-0.1PT showed nearly zero temperature coefficient of capacitance in the range of -20∼30$^{\circ}C$ and sum of dissipation factor of each layer.

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Microwave Dielectric Properties of 0.7Ba(Mg,Ta)O$_3$-0.3Ba(Co,Nb)O$_3$Ceramics with Sintering Temperature (소결온도에 따른 0.7Ba(Mg,Ta)O$_3$-0.3Ba(Co,Nb)O$_3$세라믹스 마이크로파 유전특성에 관한연구)

  • Lee, Moon-Kee;Kim, Nam-Young;Lee, Young-Hie
    • The Transactions of the Korean Institute of Electrical Engineers C
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    • v.50 no.3
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    • pp.110-114
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    • 2001
  • $0.7Ba(Mg{\frac}_{1}{3}Ta{\frac}_{1}{3})O_3-0.3Ba({\frac}_{1}{3}Nb{\frac}_{1}{3})O_3ceramics$ were prepared by the conventional mixed oxide method. The ceramics were sintered at the temperature of $1500{\sim}1575[^{\circ}C]$ for 5 hours in air. The microwave dielectric properties of the specimens were investigated with sintering temperature. The 0.7BMT-0.3BCN ceramics showed typical XRD patterns of the complex perovskite structure. Dielectric constant and quality factor were increased with increasing the sintering temperature. In the case of the specimens sintered at $1575[^{\circ}C]$ for 5 hours, dielectric constant, quality factor and temperature coefficient of resonant frequency were good values of 28,23545 at 10[㎓] and -1.2 $[ppm/^{\circ}C]$, respectively.

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Interaction of Alkali Oxide and $SO_3$ on $3CaO.SiO_2$ Formation and Microstructure ($3CaO.SiO_2$ 생성반응과 미세조직에 있어서 Alkali Oxide와 $SO_3$의 상호작용)

  • 정해문;최상흘
    • Journal of the Korean Ceramic Society
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    • v.30 no.12
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    • pp.1071-1079
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    • 1993
  • Interaction of alkali oxides and SO3 and C3S formation and microstructure was studied using K2CO3 and Na2CO3 as alkali sources and (NH4)2SO4 for SO3. When SO3/K2O=1.43 as mole ratio, K2O and SO3 react to form K2SO4, this phase is immiscible with other oxide melt and thus could not affect C3S formation as well as its microstructure. In a condition of SO3/K2O 1, C3S crystals were round and grown in a much larger size. With addition of Na2O and SO3 by only 1wt% each, C3S formation was strongly hindered. Since C2S was stabilized by Na+ and SO4-2, it could not react to give C3S formation. However in the condition of SO3/Na2O=1.43, a little amount of C3S was formed. It is considered that small amount of Na2SO4 was formed, this phase was immiscible with clinker liquid, and the C3S crystals were formed locally in the liquid part of relatively low Na2O and SO3 compositions. These crystals had irregular and rough surfaces and contained more inclusions than those grown from K2O.SO3 system.

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PEBAX-2533/Ag Salt/Al(NO3)3 Composite Using AgCF3SO3 for Facilitated Olefin Transport Membrane (올레핀 촉진수송 분리막용 AgCF3SO3를 활용한 PEBAX-2533/Ag Salt/Al(NO3)3 복합체)

  • Kim, Soyoung;Kang, Sang Wook
    • Membrane Journal
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    • v.31 no.1
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    • pp.61-66
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    • 2021
  • This study was a study on an facilitated transport membrane to replace the cryogenic separation method currently used in olefin/paraffin separation. Cost reduction is also a very important factor to commercialize facilitated transport membranes. However, AgBF4, which has been studied a lot, is a relatively expensive silver salt. To replace this, a PEBAX-2533/ AgCF3SO3/Al(NO3)3 composite film was prepared using relatively inexpensive AgCF3SO3. It was analyzed through SEM, FT-IR, and RAMAN. Through this study, it was confirmed that the polymer matrix affects the long-term stability.

Histone H3K4 Methyltransferase SET1A Stimulates the Adipogenesis of 3T3-L1 Preadipocytes (히스톤 H3K4 메칠화효소 SET1A에 의한 지방세포 분화 촉진)

  • Kim, Seon Hoo;Jung, Myeong Ho
    • Journal of Life Science
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    • v.27 no.10
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    • pp.1104-1110
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    • 2017
  • SET1A is a histone H3K4 methyltransferase that catalyzes di- and trimethylation of histone H3 at lysine 4 (H3K4). Mono-, di-, and trimethylations on H3K4 (H3K4me1, H3K4me2, and H3K4me3, respectively) are generally correlated with gene activation. Although H3K4 methylation is associated with the stimulation of adipogenesis of 3T3-L1 preadipocytes, it remains unknown whether SET1A plays a role in the regulation of adipogenesis of 3T3-L1 preadipocytes. Here, we investigated whether SET1A regulates 3T3-L1 preadipocytes' adipogenesis and characterized the mechanism involved in this regulation. SET1A expression increased during 3T3-L1 preadipocytes' adipogenesis. Consistent with the increased SET1A expression, the global H3K4me3 level had also increased on day 2 after the induction of adipogenesis in 3T3-L1 adipocytes. SET1A knockdown using siRNA in 3T3-L1 preadipocytes inhibited 3T3-L1 preadipocytes' adipogenesis, as assessed by Oil Red O staining and the expression of adipogenic genes, indicating that SET1A stimulates the adipogenesis of 3T3-L1 preadipocytes. SET1A knockdown inhibited the cell proliferation of 3T3-L1 cells during mitotic clonal expansion (MCE) via down-regulation of the cell cycle gene cyclin E1, as well as the DNA synthesis gene, dihydrofolate reductase. Furthermore, SET1A knockdown repressed peroxisome proliferator-activated receptor gamma ($PPAR{\gamma}$) expression during the late stage of adipogenesis. These results indicate that SET1A stimulates MCE and $PPAR{\gamma}$ expression, which leads to the promotion of 3T3-L1 preadipocytes' adipogenesis.

A Image-based 3-D Shape Reconstruction using Pyramidal Volume Intersection (피라미드 볼륨 교차기법을 이용한 영상기반의 3차원 형상 복원)

  • Lee Sang-Wook
    • Journal of the Korea Institute of Information and Communication Engineering
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    • v.10 no.1
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    • pp.127-135
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    • 2006
  • The image-based 3D modeling is the technique of generating a 3D graphic model from images acquired using cameras. It is being researched as an alternative technique for the expensive 3D scanner. In this paper, I propose the image-based 3D modeling system using calibrated camera. The proposed algorithm for rendering 3D model is consisted of three steps, camera calibration, 3D shape reconstruction and 3D surface generation step. In the camera calibration step, I estimate the camera matrix for the image aquisition camera. In the 3D shape reconstruction step, I calculate 3D volume data from silhouette using pyramidal volume intersection. In the 3D surface generation step, the reconstructed volume data is converted to 3D mesh surface. As shown the result, I generated relatively accurate 3D model.

Fabrication of Mg3Sb2 and Mg3Bi2 Compounds and their composites by mechanical alloying (기계적 합금법에 의한 Mg3Bi2와 Mg3Sb2 화합물 및 복합체의 제조)

  • Kim, In-Ki
    • Journal of the Korean Crystal Growth and Crystal Technology
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    • v.23 no.4
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    • pp.189-194
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    • 2013
  • Single phase crystalline powders of $Mg_3Sb_2$ and $Mg_3Bi_2$ were prepared by mechanical alloying Mg, Sb and Bi metals with planetary ball milling for 24~48 h. The compositions of starting raw materials for single phase $Mg_3Sb_2$ and $Mg_3Bi_2$ were 3Mg : 1.8Sb and 3Mg : 1.6Bi, respectively. Two types of mechanically alloyed powders obtained were mixed at some ratios for the fabrication of $Mg_3Sb_2-Mg_3Bi_2$ composites and then hot pressed under uniaxial pressure of 70 MPa at 723 K for 1 h. The main phase of composites was a stable phase similar to $Mg_3Bi_2$ phase with a small amount of Bi phase. The distributions of Sb and Bi elements on EDS mapping images were discontinuous and their compositional contours were clear, which means that the hot pressed specimens were composites composed of two compounds of $Mg_3Sb_2$ and $Mg_3Bi_2$.