• Bulletin of the Korean Chemical Society
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• v.24 no.11
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• pp.1605-1608
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• 2003

To development an immunodetection method for DDT, 1,1,1-trichloro-2,2-bis(4-chorophenyl)ethane (p,p'-DDT) and its metabolites (p,p'-DDA, p,p'-DDE, p,p'-DDD), five derivatives of DDT haptens have been synthesised and characterized as coating ligands for antibody evaluation. The appropriate lengths of linkers were introduced to investigate a matching pair of coating ligand and antibody. Among these hapten derivatives, 2,2-bis(4-chlorophenyl)acetic acid (DDA), 5,5-bis(4-chlorophenyl)-5-hydroxypentanoic acid (DDHP) and 5,5-bis(4-chlorophenyl)-5-chloropentanoic acid (DDCP) were conjugated with keyhole limpet hemocyanin (KLH) for its use as an immunogen. The bovine serum albumin (BSA) conjugates of these derivatives were prepared as a coating ligand for monoclonal antibody screening. Fifteen monoclonal antibody clones were screened using these probes. 6,6-Bis(4-chlorophenyl)-6-hydroxyhexanoic acid (DDHH) and 3-[6,6-Bis(4-chlorophenyl)-6-hydroxyhexanoylamino]propanoic acid (DDHHAP), in addition to the above hapten derivatives, were conjugated to ovualbumin (OVA) and bovine serum albumin (BSA) for their use as coating ligands to measure the titration level of the antibody and the displacement of free analytes. The indirect competitive ELISA results indicate that the titration level and free analyte displacement were greatly influenced by the DDT derivatives and carrier proteins used. Three matching pairs of monoclonal antibodies and coating ligands were selected for the DDT immunoassay: antibody clone 1A3 and coating ligand DDA-OVA, 1A1 and DDHHAP-BSA, and 1A4 and DDHP-OVA.

• Journal of the Korea Convergence Society
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• v.12 no.12
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• pp.125-137
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• 2021

This study is a descriptive investigation study to identify the Convergence factors of the subjective health status, communication with medical personnel and drug misuse on medication adherence. The subjects of this study were 179 senior citizens who used community elderly welfare centers. Data were collected from January 13, 2020 to January 17, 2020. Data analysis was performed using frequency, percentage, mean, standard deviation, t-test, ANOVA. Post-Hoc Test Was performed using Scheffe test, Pearson's correlation coefficients and multiple regression analysis. The regression equation of this study explained 24% of medication adherence. Drug misuse(𝛽=-4.32, p=<.001) was the factor that had the greatest influence on the medication adherence, followed by the presence or absence of chronic disease (𝛽=-3.04, p=.003), marital status (𝛽=2.64, p=.009), and communication with medical personnel (𝛽=2.26, p=.025 ) in that order. Therefore, it is necessary to establish a convergence system of medication adherence for the elderly using community welfare centers.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.24 no.10
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• pp.1384-1389
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• 2020

Although the fintech industry is developing rapidly around the world, the domestic development situation is rather slow compared to the speed. Therefore, the future development direction can be set by analyzing the current status of the fintech industry in order to suggest the direction of development in the domestic fintech industry. The main services provided by companies belonging to the domestic fintech industry are in the areas of remittance settlement, financial investment, asset management, crowdfunding, P2P finance, overseas remittance, fintech SI, insurtech, virtual currency, security, and authentication. It is divided into. This study identifies the main technologies used in the service and grasps the current domestic status. In addition, it analyzes the distribution of workers by each service. This study is expected to play an important role in the development of the financial industry through technical analysis of fintech companies.

• Journal of the Korean Applied Science and Technology
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• v.39 no.2
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• pp.182-192
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• 2022

The purpose of this study was to investigate the effects of flow experience and learning competency on learning satisfaction after virtual simulation-based nursing practice education for the elderly. The subjects of this study were 72 nursing students and data were collected through online surveys from April 2 to May 7, 2021. Data were analyzed using the SPSS/WIN 24.0 program by descriptive statistics, Pearson's correlation, multiple regression analysis. As a result of the study, the learning satisfaction of nursing students after virtual simulation education showed a significant positive correlation with flow experience (r=.656, p<.001) and learning competency (r=.672, p<.001). The most influential factors on learning satisfaction were learning competency (𝛽=.459, p<.001) and flow experience (𝛽=.413, p<.001), and the explanatory power of the model was 60.9%. Therefore, in order to improve learning satisfaction after virtual simulation education, it is suggested to develop ways to promote flow experience in practice and improve individual learning capabilities.

• Journal of Industrial Convergence
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• v.22 no.8
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• pp.73-83
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• 2024

The study attempted to examine the effects of hybrid simulation practice program on critical thinking disposition, self-efficacy, communication competency, and clinical competency of nursing students. The study was one group pre-test and post-test design. Data were collected between April 24 to May 5, 2023 from 35 nursing students. The collected data was analyzed using the SPSS 25.0 program, frequency analysis, mean, standard deviation, and paired t-test. Research results showed that nursing students' critical thinking disposition(t=7.01, p<.001), self-efficacy(t=2.17, p=.037), communication competency(t=2.70, p=.011), and clinical competency(t=6.60, p<.001) were improved after the simulation program. The hybrid simulation practice program is significant in that it applies various learning tools, including high-fidelity-low-fidelity-role play to strengthen the connection between nursing students' theory and practice.

• The Journal of Korean Physical Therapy
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• v.12 no.1
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• pp.57-63
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• 2000

The purpose of this study was to evaluate of balance performance and to examine the relationship between balance performance and feet position, platform speed. Twenty two subjects(men 8, women 14, mean age 24.45years) performed nine balance test with eyes closed for 25seconds:3 feet position(feet together, feet 12cm in apart, feet 24cm in apart) and 3 platform speed$(100\%,\;70\%,\;40\%)$. The results were as fellows: 1. There are significant difference between center of balance and feet position(p<0.05). 2. There are no significant difference between center of balance and plaform speed(p<0.05). 3. There are significant difference between sway index and feet position(p<0.05). 4. There are significant difference between away index and plaform speed(p<0.05).

• Natural Product Sciences
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• v.24 no.4
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• pp.293-297
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• 2018

Sasa quelpaertensis Nakai leaves contain a mixture of polysaccharides, amino acids, and polyphenols, which mediate various biological activities. For efficient utilization of its leaf, we reported the preparation procedure for phytochemical-rich extract (PRE) using the leaf residue, which was by-product of hot water extraction. This study was undertaken to evaluate the effects of PRE and its major constituent, p-coumaric acid,on the growth of several human cancer cell lines (MKN-74, MKN-45, SNU-1, SNU-16, and HL-60). The ethyl acetate fraction of PRE and p-coumaric acid significantly inhibited the proliferation of MKN-74 and HL-60 cells, respectively, and induced cell apoptosis, down-regulated Bcl-2 and poly (ADP-ribose) polymerase levels, and up-regulated those of Bax and caspase-3. These results show the potential utility of S. quelpaertensis Nakai leaves in cancer prevention.

• Proceedings of the PSK Conference
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• 2003.10b
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• pp.97.3-98
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• 2003

The inhibitory effects of tetrahydropapaverine on serotonin biosynthesis in serotonin-producing murine mastocytoma P815 cells were investigated. Tetrahydropapaverine at concentration ranges of 5-20 M decreased serotonin content in a concentration-dependent manner in P815 cells and showed 42.1 % inhibition of serotonin content at 5.0 M for 24 hr. The value of 50 % inhibitory concentration, IC$\sub$50/, of tetrahydropapaverine was 6.2 M. Under these conditions, tryptophan hydroxylase (EC 1.14.16.4, TPH), was inhibited for 24-36 hr after treatment with tetrahydropapaverine in P815 cells(49.1 % inhibition at 7.5 M). (omitted)

• Journal of Korean Society of Environmental Engineers
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• v.27 no.11
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• pp.1180-1185
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• 2005

Iron sand, having iron as a major component, was applied in the treatment of synthetic wastewater containing Cu(II) or Pb(II). To investigate the stability of iron sand at acidic condition, dissolution of Fe and Al was studied with variation of solution pH ranging from 2 to 4.5. Iron concentration in the extracted solution was below the emission regulation of wastewater even at a strong acidic condition, pH 2. Although an important concentration of aluminum was extracted at pH 2, the dissolution greatly decreased above pH 3. This stability test suggests that application of iron sand has little problem in the treatment of wastewater above pH 3. Adsorption capacity of Cu(II) and Pb(II) onto iron sand was investigated in a batch and a column test. In case of Cu(II), rapid adsorption was noted, showing 50% removal within 2 hrs, and then reached a near complete equilibrium after 24 hrs. Adsorption was favorable at higher pH in each metal ion and showed a near complete removal above pH 6, indicating a typical cationic-type adsorption. From the adsorption isotherm obtained with variation of the concentration of each metal ion, the maximum adsorption capacity of Cu(II) and Pb(II) was identified as 2,170 mg/kg 및 3,450 mg/kg, respectively.

• Bulletin of the Korean Chemical Society
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• v.24 no.6
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• pp.739-743
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• 2003

New quaternary compounds $ANb_2PS_{10}$ (A = Na, Ag) and $AuNb_4P_2S_{20}$ were synthesized and characterized. The structures of three compounds consist of one-dimensional infinite chains built by [$Nb_2S_{12}$] and [$PS_4$] units. Cation atoms are occupied within the van der Waals gap of sulfur atoms between infinite chains to make -S…$M^+$…S- contacts. There is only one Au atom site and so crystallographically a unit cell contains four equivalent Au atoms in $AuNb_4P_2S_{20}$. This is only the half of the numbers of Na or Ag atoms in $NaNb_2PS_{10}$ or $AgNb_2PS_{10}$. The ratio between $Nb_2PS_{10}$ matrix vs the cation is, therefore, 1 : 1 for Ag and Na, but it is 2 : 1 for Au. Mixed valency in Au or Nb was expected to balance the charge in the latter compound. The electronic structures calculated based on the extended Huckel tight-binding method show that $ANb_2PS_{10}$ (A = Ag, Na) are semiconducting, while $AuNb_4P_2S_{20}$ is metallic, which is not consistent with the experimental results of these three compounds that all exhibit semiconducting property. The result of calculation suggests that $AuNb_4P_2S_{20}$ might be a magnetic insulator. Magnetic measurement experiment exactly proved that the compound is a Slater antiferromagnetic material with the Neels' temperature of 45 K. It is recognized, therefore, that electronic structure analysis is very useful to understand the properties of compounds.