• Title/Summary/Keyword: 2p24

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Application of HMO for Reactivity of the Benzologous Pyridine Ligands (Ⅱ) (Benzologous Pyridine 계 리간드의 반응성에 대한 HMO 의 응용(제 2보))

  • Ja Hong Kim;Gae Soo Lee
    • Journal of the Korean Chemical Society
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    • v.24 no.1
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    • pp.20-24
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    • 1980
  • The frontier electron densities and pK values for benzologous pyridine ligands are calculated using the HMO. Linear regression formula for pK in protonation of ligands is derived from the electron densities and observed pK values. The calculated pK values are in agreement with those of experimental values and a parallelism is shown between pK and qN. The reactivities for electrophilic, nucleophilic and radical reactions have also been calculated respectively by frontier electron densities.

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Sexual Maturation, Attitudes towards Sexual Maturity, and Body Esteem in Elementary-School Children (초등학생의 성 성숙, 성 성숙 태도 및 신체 자존감)

  • Park, Sunah;Choi, Eunyoung;Lee, Eunhee;Byeon, Mikyeong;Lee, Byeongju;Jung, Kyea
    • Women's Health Nursing
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    • v.24 no.2
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    • pp.219-228
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    • 2018
  • Purpose: The purpose of this study is to evaluate sexual maturation, attitudes toward sexual maturity, and body esteem in the sexual development of Korean elementary-school boys and girls. Methods: A descriptive cross-sectional study was conducted with 399 fifth and sixth graders (192 boys and 207 girls). The data were analysed with a $x^2$ test, t-test, and Pearson correlation coefficients. Results: Among the 207 girls, 70.5% had pubic hair growth, 68.1% had breast development, and 56.0% had a menstrual period. In boys, 59.4% of the 192 subjects experienced the development of external genitalia and 52.6% had pubic hair growth. Sexual maturation was related to grade (boys, t=7.07, p=.008; girls, t=12.76, p<.001), age (t=-2.20, p=.030; t=-4.11, p<.001), height (t=-5.16, p<.001; t=-7.52, p<.001), and weight (t=-2.89, p=.004; t=-5.19, p<.001) in both boys and girls. Girls were more likely to have sexual maturity than boys ($x^2=22.29$, p<.001). Boys showed more positive attitudes toward sexual maturity (t=2.10, p=.036) and higher body esteem (t=2.12, p=.035) than girls. Conclusion: This study shows that sexual maturation, attitude toward sexual maturity, and body esteem in sexual development differ between boys and girls. The findings indicate that it is necessary to develop a tailored sex-education program according to the sex of elementary-school children.

Regulation of Apoptosis and Cell Cycle in Irradiated Mouse Brain (마우스의 대뇌조직에서 방사선에 의한 아포토시스와 세포주기의 조절)

  • Oh, Won-Yong;Song, Mi-Hee;Chung, Eun-Ji;Seong, Jin-Sil;Suh, Chang-Ok
    • Radiation Oncology Journal
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    • v.19 no.2
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    • pp.146-152
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    • 2001
  • Purpose : To investigate the regulation of apoptosis and cell cycle in mouse brain irradiation. Materials and Methods : 8-week old male mice, C57B1/6J were given whole body $\gamma-radiation$ with a single dose of 25 Gy using Cobalt 60 irradiator. At different times 1, 2, 4, 8 and 24hr after irradiation, mice were killed and brain tissues were collected. Apoptotic cells were scored by TUNEL assay. Expression of p53, Bcl-2, and Bax and cell cycle regulating molecules; cyclins Bl, Dl, E and cdk2, cdk4, $p34^{cdc2}$ were analysed by Western blotting. Cell cycle was analysed by Flow cytometry. Results : The peak of radiation induced apoptosis is shown at 8 hour after radiation. With a single 25 Gy irradiation, the peak of apoptotic index in C57B1/6J is $24.0{\pm}0.25$ (p<0.05) at 8 hour after radiation. Radiation upregulated the expression of p53/tubulin, Bax/tubulin, and Bcl-2/tubulin with 1.3, 1.1 and 1.45 fold increase, respectively were shown at the peak level at 8 hour after radiation. The levels of cell cycle regulating molecules after radiation are not changed significantly except cyclin D1 with 1.3 fold increase. Fractions of Go-Gl, G2-M and S phase in the cell cycle does not specific changes by time. Conclusion : In mouse brain tissue, radiation induced apoptosis is particularly shown in a specific area, subependyma. These results and lack of radiation induced changes in cell cycle ofter better understanding of radiation response of noraml brain tissue.

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일부 폐경전 성인여성의 골밀도와 신체계측 및 식이인자에 관한 연구

  • 임화재
    • Proceedings of the KSCN Conference
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    • 2003.11a
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    • pp.1071-1071
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    • 2003
  • 본 연구는 폐경전 성인여성들의 골격상태를 알아보고 신체계측 및 식이섭취실태가 골밀도에 미치는 영향을 평가하기 위해서 성인여성 61명을 대상으로 신체계측을 실시하고 24시간 회상법으로 영양소 및 주요 식품군의 식품섭취실태를 조사하고 DEXA를 사용하여 요추와 대퇴부 3부위의 골밀도를 측정하였다. 1) 대상자들의 평균 연령은 37세였으며, 평균 신장과 체중은 158.17cm, 54.55kg였으며, 평균 BMI와 WHR은 21.82, 0.78로 대상자들의 비만도는 정상이었다. 2) 평균 골밀도는 요추(L24) 1.04 g/$\textrm{cm}^2$, 대퇴경부 0.76g/$\textrm{cm}^2$, 대퇴전자부 0.66g/$\textrm{cm}^2$, 와드삼각부 0.69g/$\textrm{cm}^2$이었다. 3) T-score로 판정시 요추(L24)의 경우 골다공증군 3.28%, 골감소증군 14.75%, 대퇴경부의 경우 골다공증군 9.84%, 골감소증군 52.46%, 대퇴전자부의 경우 골다공증군 1.64%, 골감소증군 34.43%, 와드삼각부의 경우 골다공증군 6.56%, 골감소증군 45.90%였다. 4) 영양소중 칼슘(78.75%), 철분(69.75%) 및 비타민 A(92.17%) 영양소의 1일 평균 섭취량은 영양권장량보다 낮은 수준이었다. 5) 신체계측 및 영양소섭취량과 골밀도와의 상관관계분석에서 신체계측에서 체중(p < 0.05), 엉덩이둘레(p < 0.01), 제지방함량(p < 0.05), 총수분함량(p < 0.05)이 높을수록 요추골밀도가 유의하게 높았으나, 영양소섭취량은 골밀도와 유의한 상관성을 보이지 않았다. 6) 주요 식품군의 식품섭취실태와 골밀도와의 상관관계분석에서 버섯군의 식품섭취횟수(p < 0.05, p < 0.05)가 많을수록 요추(L3, L24)의 골밀도가 각각 유의하게 높았으며, 유지류군의 섭취식품수(p < 0.05)가 많을수록 와드삼각부의 골밀도가 유의하게 높았으나 곡류군의 섭취식품수(P < 0.01, p < 0.05, p < 0.05)가 많을수록 대퇴부 3부위 (대퇴경부, 대퇴전자부 및 와드삼각부)의 골밀도가 각각 유의하게 낮은 것으로 나타났다. 이상의 결과에서 폐경전 성인여성의 경우 요추보다는 대퇴부 3부위의 경우 골다공증이나 골감소증의 비율이 상대적으로 높았으며, 특히 대퇴경부에 있어서 골다공증이나 골감소증의 비율이 가장 높았음을 알 수 있다. 또한 요추와 대퇴부 3부위의 골밀도는 영양소섭취량과 유의한 상관관계를 보이지 않았으나 체중, 엉덩이둘레 등의 신체계측요인과 곡류군, 버섯군 및 유지류군 등의 주요 식품군의 식품섭취실태와 밀접한 상관관계를 보이고 있음을 알 수 있다. 따라서 성인여성에 있어서 골밀도손실을 예방하기 위해 평상시 적절한 체중유지와 아울러 식생활지침에 있어서 주요식품군별로 적절한 섭취식품의 수, 섭취량 및 섭취빈도에 대한 영양교육이 필요한 것으로 생각된다.

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A Study on Artificiality Salivary pH and Sugar Fermentation Test of Caries Potentiality Foods (우식유발식품에 의한 인공타액내 pH 변화와 당 분해 효소 활성에 관한 연구)

  • Ji, Yun-Jeong;Park, Su-Kyung
    • Journal of dental hygiene science
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    • v.12 no.4
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    • pp.303-309
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    • 2012
  • This study was designed to provide basic data for developing a standardized caries potentiality index to help to choose snack foods with a low score on the index by investigating adolescents' snack intakes and measuring them in total saccharinity, pH, and acidogenic potential and glucosidase activity of Streptococcus mutans (S. mutans). Total 28 snack foods were selected and measured for total saccharinity (Pocket refractometer PAL-1, ATAGO) and pH with a pH meter (Mentor, Seoul, Korea). Artificial saliva was added to each sample. The experiment group was administered with S. mutans (ATCC 3692), cultured in a constant temperature incubator at $37^{\circ}C$, and measured for pH changes over five times including after 10 minutes, 30 minutes, 1 hour, and 24 hours. Each sample of 0.3 ml was added to tubes containing sucrose, galactose, or glucose to measure the glucosidase activity of S. mutans. They were then observed for glucosidase activity with colorimetry after 24 hours of culture in a constant temperature incubator at $37^{\circ}C$. The mean pH by the acidogenic potential of S. mutans was pH 5.33. The experiment group dropped in pH more than the control group due to the increasing acidogenic potential of S. mutans by glucosidase activity, recording pH 5.27 after 10 minutes, pH 5.21 after 30 minutes, pH 5.15 after 1 hour, and pH 4.80 after 24 hours. The observation results of glucosidase activity of S. mutans with colorimetry show that most of the samples were positive in orange and yellow with glucose, sucrose, and glactose recording activity of 78.58%, 75%, and 71.42%, respectively.

A Study of Characteristics of Foot Pressure Distribution in Trans-tibial Amputee Subjects (하퇴 의지 사용자의 족저압 분포 특성에 관한 연구)

  • Kim, Jang-Hwan;Cynn, Heon-Seock
    • Physical Therapy Korea
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    • v.8 no.3
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    • pp.1-10
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    • 2001
  • The purpose of this study was to compare the static pressure, dynamic pressure, dynamic pressure-time integral, relative impulse, and contact time between the sound lower limb and amputated lower limb in trans-tibial amputee subjects using Parotec system. Seventeen trans-tibial amputee subjects wearing endoskeletal trans-tibial prosthesis voluntarily participated in this study. The results were as follows: 1) In static standing condition, there were significantly higher static pressure in sound lower limb insole sensor of 10, 14, 15, 18, 19, 23, and 24 and in amputated lower limb insole sensor of 9, 12, and 16 (p<.05). 2) In dynamic gait condition, there were significantly higher dynamic pressure in sound lower limb insole sensor of 2, 18, 22, 23, and 24 and in amputated lower limb insole sensor of 5, 9, 10, 11, 12, 14, 15, and 16 (p<.05). 3) In dynamic gait condition, there were significantly higher pressure-time integral in sound lower limb insole sensor of 2, 4, 18, 19, 20, 21, 23, and 24 and in amputated lower limb insole sensor of 5, 11, 12, and 15 (p<.05). 4) In dynamic gait condition, there were significantly higher relative impulse in sound lower limb insole sensor of 18, 19, 20, 22, 23, and 24 and in amputated lower limb insole sensor of 5, 9, 10, 11, 12, and 15 (p<.05). 5) In dynamic gait condition, there was significantly higher percentage of contact time in push off phase of sound lower limb and in support phase of amputated lower limb (p<.05). These results suggest that trans-tibial amputee subjects had characteristics of shortened push off phase due to unutilized forefoot and of lengthened support phase with higher pressure in the midfoot.

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Optimized Culture Condition and Enzyme Activity of the Mycelia of Clavicorona pyxidata (좀나무싸리버섯(Clavicorona pyxidata)의 균사체 최적 배양조건 및 세포효소활성 특성)

  • Lee Tae-Hee;Kim Jin-Man;Han Yeong-Hwan
    • Korean Journal of Microbiology
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    • v.42 no.2
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    • pp.131-134
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    • 2006
  • The culture conditions for the enhanced mycelial of Clavicorona pyxidata DGUM 29005 were investigated. The optimal temperature and pH for the mycelial growth were $24^{\circ}C$ and 5.0, respectively. It was shown that trehalose was the best supplement of carbon sources in Czapek-Dox medium as a minimal medium for enhanced mycelial growth. In general, inorganic nitrogen sources were better than organic ones for mycelial growth. Calcium nitrate was the best out of the inorganic nitrogen test. The appropriate phosphorous and vitamin were $Na_2HPO_4$ and p-aminobenzoic acid, respectively. After the mycelial of C. pyxidata DGUM 29005 was cultivated at $24^{\circ}C$ for 20 days in MEM broth(pH 5.0), the specific activities of both exomycelial and endomycelial enzymes were determined. Among the exomycelial enzyme assayed, the specific activity of laccase was much higher than those of other enzymes. However, little or no enzyme activities of ${\alpha}$-amylase, chitinase, lipase and pretense were found.

Compact LTCC Patch Antenna Integrating a Wideband Vertical Transition for millimeter-wave SoP Applications (밀리미터파 SoP 응용을 위해 광대역 수직천이를 집적한 초소형 LTCC 팻치안테나)

  • Lee, Young Chul
    • Journal of Korea Society of Industrial Information Systems
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    • v.19 no.1
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    • pp.19-24
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    • 2014
  • In this work, a compact patch antenna based on a low temperature cofired ceramic (LTCC) has been presented for V-band system-on-package (SoP) applications. In order to integrate it with transceiver block, a waveguide (W/G) to embedded microstrip line (eMSL) vertical transition was designed using slot-fed double stacked patch antennas for easy assembly and wide bandwidth. The $2{\times}2$ patch antenna integrating the transition was designed and fabricated in the 5-layer LTCC dielectrics. The whole size of the fabricated antenna including the $2{\times}2$ patches, transition and W/G was $20{\times}24{\times}5.39mm^3$. The fabricated antenna has achieved a 10 dB impedance bandwidth of 2.45 GHz from 61 to 63.45 GHz.

Comparison of Quality Characteristics in Dry-Cured Ham at Initial Stage of Distribution (유통초기단계의 건조- 숙성햄의 품질특성 비교)

  • Jin, Sang-Keun;Kim, Il-Suk;Yang, Mi-Ra;Hur, In-Chul;Kim, Dae-Seung;Kang, Suk-Nam
    • Journal of Animal Science and Technology
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    • v.53 no.4
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    • pp.377-385
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    • 2011
  • This study was carried out to investigate quality characteristics of dry-cured hams in the domestic market. Two kinds of dry-cured hams were processed with pork leg (T1) and pork neck (T2). Five 24-month dry-cured legs (T1, 5.3-6.1 kg) and twenty 4-month dry-cured pork necks (T2, 1.5-1.9 kg) were used in this experiment. They were stored at $4^{\circ}C$ chilling room and quality characteristics were investigated. Moisture content, water activity, cholesterol content, CIE $L^*$, VBN, total plate counts and lactic acid bacteria of T1 were significantly higher (p<0.05) than those of T2, whereas fat content, ${NO_2}^-$, CIE $a^*$, TBARS and Warner-Bratzler shear force values of T2 were significantly higher (p<0.05) than those of T1. In fatty acid compositions, palmitoleic acid and stearic acid in T2 were significantly higher (p<0.05) than T1, however, oleic and linoleic acid in T2 was significantly lower (p<0.05) than T1. In free amino acids, the total content and individual content of asparagin, leucine and phenylalanine in T1 were higher than those of T2 (p<0.05). The aroma score of T2 was higher than that of T1 in sensory evaluation (p<0.05). In conclusion, two kinds of dry-cured hams were different in their final characteristics and could enhance the consumer's appeal of pork meat in Korean market.

Aroma Pattern Analysis of Hanwoo Beef (M. longissimus) using Electronic Nose during Refrigerated Storage (전자 코를 이용한 한우 등심육의 냉장저장 중 향기 패턴 분석)

  • Lee Sung Ki;Kim Ju Yong;Kim Yong Sun
    • Food Science of Animal Resources
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    • v.24 no.3
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    • pp.260-265
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    • 2004
  • This study was carried out to investigate aroma patterns of Hanwoo (Korean cattle) beef using electronic nose during refrigerated storage, and to compare these results with chemical quality (pH, TBARS). The M. longissimus muscle from Hanwoo carcasses after 24 hrs postmortem was obtained and stored at 5${\pm}$1$^{\circ}C$ for 7 days. Sensitivity (dR/RO) values among electronic nose data were changed differently during refrigerated storage, and showed significant difference on the 7th day of storage (p<0.01). The dR/RO from SY/G, SY/AA, SY/Gh, SY/gCTl, SY/gCT decreased but those from SY/LG, T30/1, P10/1, P10/2, P40/1, T70/2, PA2 increased during storage for 7 days. Mapping these data using PCA (principal component analysis) showed that the 1st day data were present in the middle of the right side, the 3rd day data were present in bottom part of this area and the 7th day data spread out more widely on the left side. In case of DFA (discriminant factor analysis), the flock clustered round and located in different side clearly comparing with PCA plot. In analysis of correlation coefficients among electronic nose data and chemical quality data, there was significant correlation among sensor data (p<0.001). But pH and TBARS were not significantly correlated with electronic nose data. Consequently, PCA and DFA plot by electronic nose data showed difference during refrigerated storage and there were significant correlations among sensors. Therefore it will be possible to detect separate aroma patterns of Hanwoo beef using electronic nose.