• Journal of The Korean Society of Grassland and Forage Science
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• v.39 no.1
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• pp.24-30
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• 2019

This study was conducted to investigate the effect of seeding dates on grassland productivity and botanical composition in oversown pasture located in Cheonan of South Korea. Four treatment groups were established based on the seeding dates: 18th August, 1st September, 15th September and 29th September. Evaluation of seasonal changes in botanical composition of pasture showed that the highest ratios of grass in 18th August and 1st September (pasture species 93% and weeds 7%) and the lowest in 15th September (pasture species 75% and weeds 25%). In the plant length, there is no significantly different in 5% probability level. In the total dry matter yield of grass, 18th August ($13,362kg\;ha^{-1}$) and 1st September ($13,988kg\;ha^{-1}$) were higher than 15th September ($11,883kg\;ha^{-1}$) and 29th September ($11,459kg\;ha^{-1}$). The findings of the this study suggest that seeding by early September the most desirable results for botanical composition and grassland productivity in oversown pasture, Cheonan of South Korea.

• The Journal of the Convergence on Culture Technology
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• v.7 no.4
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• pp.479-490
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• 2021

As a part of Korean accounting reforms through the improvement of the accounting and audit related systems, the amendment bill of 'Act on External Audit of Stock Compamies's was passed in the Natinal Assembly plenary session in 2017, the amended act has been enforced except some regulations since the business year on November 1, 2018, and all the amended matters will be applied from the business year of 2024. The reasons for auditor designation in 2019 are 'pre-IPO' 331 companies, 220 periodic designation companies, 197 companies that had operating loss for three consecutive years, 112 companies with issues for administration, 108 companies with excessive debt ratio and 66 companies with no auditors. Regarding the reasons for the increase of auditor designation, 475 companies were increased in accordance with the new designation standard by the amended bill of Act on External Audit of Stock Companies, 114 companies were increased due to the abolition of the considered designation system of companies to be listed, and 90 companies were increased based on the increase of listed companies incorporated to issues for administration. In 2020, 462 companies had periodical designation (434 listed, 28 non-listed), adding 242 companies (110%) over a year. In terms of direct designation, 'pre-IPO' accounted for the most (362 companies), followed by '3 consecutive years of operating loss' (245 companies), then by companies with administration issues (133 companies), and CEO & largest sharholder replacement. Regarding the designation of auditors according to accounting firms in 2020, A group that includes(top 4) accounting firms(Samil, Samjeong, Hanyeong, Anjin) had 526 companies(34.6%), which ia an incease of 72 companies from the previous year(454 companies, 37.1%), but the weight decreased by 2.5%.

• Journal of Korean Society of Forest Science
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• v.111 no.3
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• pp.365-373
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• 2022

We compared carbon stocks in tree biomass and soils of Quercus acutissima, Q. mongolica, Q. serrata, and Q. variabilis stands. A total of 531 plots (Q. acutissima: 110 plots, Q. mongolica: 177 plots, Q. serrata: 96 plots, Q. variabilis: 148 plots) were examined between 2016 and 2021 to determine the tree biomass and soil carbon stocks throughout the country. The carbon stocks of tree biomass were significantly higher in Q. mongolica (mean stand age, 57 years, 144.9 Mg C ha^-1) than in Q. variabilis (mean stand age, 43 years, 123.7 Mg C ha^-1), Q. serrata (mean stand age, 43 years, 120.1 Mg C ha^-1), and Q. acutissima (mean stand age, 36 years, 113.2 Mg C ha^-1) stands. The soil carbon concentration was significantly higher in Q. mongolica (A: 43.1 mg C g-1) than in Q. serrata (31.0 mg C g-1), Q. variabilis (25.31 mg C g-1), and Q. acutissima (24.4 mg C g-1) stands. The soil carbon stocks were significantly higher in Q. mongolica (116.8 Mg C ha^-1) than in Q. acutissima (49.3 Mg C ha^-1) stands. Total carbon stocks of tree biomass and soil were highest in Q. mongolica (262 Mg C ha^-1), followed by Q. serrata (218 Mg C ha^-1), Q. variabilis (211 Mg C ha^-1), and Q. acutissima (163 Mg C ha^-1) stands. Multiple linear regressions were performed to estimate the total carbon stocks of the four Quercus spp., and results showed that total carbon stocks increased with increasing elevation, mean diameter at breast height, and basal areas. Basal area and elevation of Quercus spp. stands were important explanatory variables based on multiple linear regressions for estimating carbon stocks.

• Journal of Radiopharmaceuticals and Molecular Probes
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• v.9 no.1
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• pp.9-16
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• 2023

Liposomes as drug delivery system have proved useful carrier for various disease, including cancer. In addition, perfluorocarbon cored microbubbles are utilized in conjunction with high-intensity focused-ultrasound (HIFU) to enable simultaneous diagnosis and treatment. However, microbubbles generally exhibit lower drug loading efficiency, so the need for the development of a novel liposome-based drug delivery material that can efficiently load and deliver drugs to targeted areas via HIFU. This study aims to develop a liposome-based drug delivery material by introducing a substance that can burst liposomes using ultrasound energy and confirm the ability to target tumors using PET imaging. Liposomes (Lipo-DOX, Lipo-DOX-Au, Lipo-DOX-Au-RGD) were synthesized with gold nanoparticles using an avidin-biotin bond, and doxorubicin was mounted inside by pH gradient method. The size distribution was measured by DLS, and encapsulation efficiency of doxorubicin was analyzed by UV-vis spectrometer. The target specificity and cytotoxicity of liposomes were assessed in vitro by glioblastoma U87mg cells to HIFU treatment and analyzed using CCK-8 assay, and fluorescence microscopy at 6-hour intervals for up to 24 hours. For the in vivo study, U87mg model mouse were injected intravenously with 1.48 MBq of ⁶⁴Cu-labeled Lipo-DOX-Au and Lipo-DOX-Au-RGD, and PET images were taken at 0, 2, 4, 8, and 24 hours. As a result, the size of liposomes was 108.3 ± 5.0 nm at Lipo-DOX-Au and 94.1 ± 12.2 nm at Lipo-DOX-Au-RGD, and it was observed that doxorubicin was mounted inside the liposome up to 52%. After 6 hours of HIFU treatment, the viability of U87mg cells treated with Lipo-DOX-Au decreased by around 20% compared to Lipo-DOX, and Lipo-DOX-Au-RGD had a higher uptake rate than Lipo-DOX. In vivo study using PET images, it was confirmed that ⁶⁴Cu-Lipo-DOX-Au-RGD was taken up into the tumor immediately after injection and maintained for up to 4 hours. In this study, drugs released from liposomes-gold nanoparticles via ultrasound and RGD targeting were confirmed by non-invasive imaging. In cell-level experiments, HIFU treatment of gold nanoparticle-coupled liposomes significantly decreased tumor survival, while RGD-liposomes exhibited high tumor targeting and rapid release in vivo imaging. It is expected that the combination of these models with ultrasound is served as an effective drug delivery material with therapeutic outcomes.

• Journal of the Korean GEO-environmental Society
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• v.24 no.12
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• pp.61-67
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• 2023

Heat pipes located underground in urban areas and operated under high temperature and pressure conditions can cause large-scale human and economic damage if damaged. In order to predict damage in advance, damage and construction information of heat pipe are analyzed to derive independent variables that have a correlation with frequency of damage, and a simple regression analysis modified model using each variable is applied to the field. However, as the correlation between independent variables applied to the model increases, the independence between variables is harmed and the reliability of the model decreases. In this study, the independence of the pipe diameter, burial depth, insulation level of monitoring system, and disconnection or short circuit of the detection line, which are judged to be interrelated, was tested to derive a method for combining variables and setting categories necessary to apply to the frequency of damage estimation model. For the test of independence, the continuous variables pipe diameter and burial depth were each converted into three categories, insulation level of monitoring system was converted into two categories, and the categorical variable disconnection or short circuit of the detection line status was kept as two categories. As a result of the test of independence, p-value between pipe diameter and burial depth, level of monitoring system and disconnection or short circuit of the detection line was lower than the significance level (α = 0.05), indicating a large correlation between them. Therefore, the pipe diameter and burial depth were combined into one variable, and the categories of the combined variable were set to 9 considering the previously set categories. The insulation level of monitoring system and the disconnection or short circuit of the detection line were also combined into one variable. Since the insulation level is unreliable when the detection line status is disconnection or short circuit, the categories of the combined variable were set to 3.

• Journal of Preventive Medicine and Public Health
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• v.3 no.1
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• pp.97-110
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• 1970

This survey was conducted to evaluate not only the present status of health center directors-their personal histories, their will to private practice in the future, their responses to governmental policies, -but also the distribution of doctorless myons, budget and subsidy, and director's opinions to the enhancement of health center activities. This survey questioned 116 health center directors and 16 health personnel from August to October of 1970 and obtained the following results; 1) The average ages of directors of kun, city, and total health centers were $43.2{\pm}7.8,\;42.1{\pm}7.7,\;and\;42.9{\pm}10.3$ respectively. 2) The average family sizes of directors of kun, city, and total health centers were $5.6{\pm}2.7,\;5.6{\pm}2.1,\;and\;5.6{\pm}2.6$ respectively. 3) Directors holding M. D. degrees were 79.3%, those holding qualified M. D. degrees ('approved director') were 20.7%. 4) M. P. H., M. S., and Ph. D. holders were 6.0%, 6.1%, and 4.3% respectively. 5) The average duration of present directorship in kun and city were 30.2 months and 20.4 months respectively. 6) The majority of directors had been employed in related fields before assuming current position : directorship at other health center 26.7%, army 22.4%, health subcenter 21.6%, private practice 19.0%. 7) Average length of directorship is 41.8 months. Average length of public health career, including health subcenter and present position, is 56.5 months. 8) Both rural and urban experience in health centers for regular directors is 16.3% and for approved directors, 12,5%. A total of 15.5% of all survey directors had experience in both rural and urban health center. 9) A total of 70.7% of health center directorships were staffed by local doctors. 10) Nearly 40% wanted to quit the directorships within 3 years and 60.3% had already experienced private practice. 11) Of the regular directors 17.4% felt strongly about devoting their lives to public health fields, but only 4.1% of the approved approved directors felt so. 12) There wire 432 doctorless myons among 996 respondent myons and 4.5 doctorless myons per kun. 13) The percentage of doctorless myon by Province are as follows, Cholla buk-do 57.2%, Cholla nam-de 55.0%, Kyungsang nam-do 52.0%, Kyungsang buk-do 49.7%, Chungchong but-do 42.4%, Kyonggi-do 32.9%. Cheju-do 30.8%, Kangwon-do 25.8%. 14) Two thirds of health critters have experienced the abscence of the director for a certain period since 1966 and the average span of the abscence was 18.2 months. 15) The percentage of doctorless myons increased proportionally with the span of the director's abscence. 16) The average budgets of health centers, kun, city and ku, were $W15.03\;million{\pm}W4.5\;million,\;W22.03\;million{\pm}W17.80\;million,\;W13.10\;million{\pm}W7.9\;million$ respectively. 17) Chunju city had the highest health budget per capita(W344) while Pusan Seo ku had the lowest(W19). 18) Director's medical subsidies are W30,000-50,000 in kun, and roughly W20,000 in city. 19) The older of priority in health center activities is T.B. control(31.1%), Family Planning and M. C. H.(28.0%), prevention of acute communicable disease and endemic disease (18.2%) and clinical care of patients(14.3%). 20) Nearly 32% opposed in principle the governmental policy of prohibiting medical doctors from going abroad. 21) Suggestions for immediate enhancing the position of director of health centers and subcenters: (1) Raise the base subsidy (48.2%), (2) Provide more opportunities for promotion (20.7%), (3) Exemption from army services(12.1%), (4) Full scholarship to medical students for this purpose only (7.8%). 22) A newly established medical school was opposed by 56.9% of the directors, however 33.6% of them approved. 23) Pertaining to the division of labor in Medicine and Pharmacy, the largest portion (31.9%) urged the immediate partial division of antibiotics and some addictive drugs to be given only by prescription. 24) More than half wanted a W70,000 level for the director's medical subsidies, white 36.2% stated W50,000. 25) Urgently needed skills in the kun are clinical pathologist (38.6%) and doctor (health center director) (25.5%); while in the city nurse (37.1%), doctors(clinical)(31.4%) and health educators(14.4%) are needed. 26) Essential treatment for the better health center administration; raising the base subsidy (22.7%), obtaining the power of personal management (19.3%) and the establishment of a Board of Health (14.3%). etc.

• Korean Journal of Environmental Biology
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• v.34 no.4
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• pp.304-313
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• 2016

One of the issues currently facing nuclear power plants is how to store spent nuclear waste materials which are contaminated with radionuclides such as $^{134}Cs$, $^{135}Cs$, and $^{137}Cs$. Bioremediation processes may offer a potent method of cleaning up radioactive cesium. However, there have only been limited reports on $Cs^+$ tolerant bacteria. In this study, we report the isolation and identification of $Cs^+$ tolerant bacteria in environmental soil and sediment. The resistant $Cs^+$ isolates were screened from enrichment cultures in R2A medium supplemented with 100 mM CsCl for 72 h, followed by microbial community analysis based on sequencing analysis from 16S rRNA gene clone libraries(NCBI's BlastN). The dominant Bacillus anthracis Roh-1 and B. cereus Roh-2 were successfully isolated from the cesium enrichment culture. Importantly, B. cereus Roh-2 is resistant to 30% more $Cs^+$ than is B. anthracis Roh-1 when treated with 50 mM CsCl. Growth experiments clearly demonstrated that the isolate had a higher tolerance to $Cs^+$. In addition, we investigated the adsorption of $0.2mg\;L^{-1}$ $Cs^+$ using B. anthracis Roh-1. The maximum $Cs^+$ biosorption capacity of B. anthracis Roh-1 was $2.01mg\;g^{-1}$ at pH 10. Thus, we show that $Cs^+$ tolerant bacterial isolates could be used for bioremediation of contaminated environments.

• Korean Journal of Food Science and Technology
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• v.25 no.5
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• pp.449-455
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• 1993

Vibrio vulnificus is a recentry recognized halophilic organism that may cause human infections. Patients infected with Vibrio vulnificus often have a history of exposure to the sea, suggesting that the organism may be common inhabitant of marine environment. In this studies 314 samples were collected from 9 sites of Chonnam coastal area, from April to Jun, 1993. Isolation rates of V. vulnificus were 7.1% in total samples, 33.3% in sea water, 55.5% in sediment, 1.7% in fish and shellfish, 6.3% in kitchen environment. In each areas of Chunnam V. vunificus were isolated from 3.6% to 11.4%. The isolation rates of V. vulnificus was correlated positively with organic matter and COD in sea warer and sediment. In sea water, Microorganism population were $4.5{\times}10^3{\sim}3.5{\times}10^5\;CFU/ml$, Vibrio strains were $1.8{\times}10^l4.6{\times}10^3\;CFU/ml$, Coliform bacteria were $1.9{\times}10^1{\times}3.7{\times}10^2\;CFU/100ml$. In sediment, Microorganism population were $4.8{\times}10^3{\sim}5.2{\times}10^5\;CFU/ml$. Vibrio strains were $1.9{\times}10^2{\sim}8.4{\times}10^4\;CFU/ml$, Coliform bacteria were $7.2{\times}10^1{\sim}9.9{\times}10^2\;CFU/100ml$.

• Clinics in Shoulder and Elbow
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• v.15 no.2
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• pp.86-90
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• 2012

Purpose: We studied the need for distal clavicle resection by comparing rotator cuff tear patients who underwent non-surgical treatment with and without acromioclavicular joint pathology. Materials and Methods: 45 cases that had been under follow up care for at least 9 months after receiving rotator cuff repair in our hospital between Jan. 2005 and Jun. 2011 had been studied. Acromioclavicular joint pathology group and control group were classified by physical examination and MRI findings. The temporal changes in shoulder joint abduction, internal and external rotation strength, ASES and KSS score of the two groups were measured and analyzed. Results: The acromioclavicular joint pathology complicated rotator cuff injury group's strength measurements for abduction, internal rotation, external rotation were each 8.05 (${\pm}4.54$), 11.33 (${\pm}6.05$), 10.24 (${\pm}5.27$) preoperatively and improved to 13.26 (${\pm}5.50$), 17.51 (${\pm}6.80$), 15.60 (${\pm}5.37$) post operatively while the KSS score and ASES score were each 49.07 (${\pm}15.28$) and 48.65 (${\pm}13.27$) preoperatively, improving to 84.48 (${\pm}10.96$) and 84.65. (${\pm}9.86$). The measurements for the group without complicating acromioclavicular pathology are as follows. The strength for abduction, internal rotation, external rotation was each 6.42 (${\pm}3.11$), 7.59 (${\pm}4.81$) and 7.93 (${\pm}4.49$) preoperatively, improving to 15.85 (${\pm}7.35$), 19.18 (${\pm}9.14$), 16.95 (${\pm}5.70$) post operatively, while the KSS score and ASES score each went from 42.12 (${\pm}6.43$) and 41.37 (${\pm}7.42$) to 83.44 (${\pm}6.30$) and 83.17 (${\pm}7.01$) respectively. The measurements for the two groups, however, did not show a statistically significant difference (p>0.05). Conclusion: Analysis of the rotator cuff injury groups with and without AC joint pathology showed that both groups had improved strength, ASES and KSS scores with no statistical difference difference among the groups. As such, it thought that conservative treatment is an acceptable alternative to distal clavicle resection.

• Journal of Preventive Medicine and Public Health
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• v.20 no.1 s.21
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• pp.147-157
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• 1987

Authors obtained the results of the investigation for healthy people through the routine health examination of public officers and school personnels in private schools which were conducted in 1986. The results were as follows; 1) Those who were above 20% incidence of body weight for 3917 study population were revealed 5.2% in males and 15.1% in females of $45{\sim}49$ years of age, 6.8% in males and 24,4% in females of $50{\sim}54$ years old, 5.8% in males and 13.5% in females of $55{\sim}59$ years old, and they showed that the incidences were significantly higher in females than in males at 0.01, 0.01 & 0.05 in P-values respectively. 2) Mean$\pm$SD of total cholesterol level for 3,265 healthy people with both sexes combined showed $181.63{\pm}34.67$ and it was $188.61{\pm}33.96$ in people of $40{\sim}59$ years old with both sexes combined. Mean$\pm$SD of fasting blood sugar level for 3,266 healthy people showed $87.28{\pm}11.67$ and that in $40{\sim}59$ years of age were $89.14{\pm}11.74$. Therefore, mean$\pm$2SD of total cholesterol and fasting blood sugar were $112.26{\sim}250.98mg/dl$ in males and $58.93{\sim}110.61mg/dl$ in females. 3) This investigation showed 3.0% in above 251 mg/dl of total cholesterol and 3.5% in above 111 mg/dl of fasting blood glucose. 4) Those who were above 251 mg/dl of total cholesterol and above 111 mg/dl of blood glucose in above 20% incidence of body weight according to the Broca' index were 12.9% and 7.6% respectively. 5) Those who have hypertension according to the criteria of WHO with obesity of above 20% incidence of body weight showed 8.4% in both sexes (8.2% in males and 8.7% in females). 6) Blood pressures increased according to more aging and gaining body weight.