• Biomolecules & Therapeutics
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• v.24 no.5
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• pp.475-481
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• 2016

PICK1, a PDZ domain-containing protein, is known to increase the reuptake activities of dopamine transporters by increasing their expressions on the cell surface. Here, we report a direct and functional interaction between PICK1 and dopamine $D_3$ receptors ($D_3R$), which act as autoreceptors to negatively regulate dopaminergic neurons. PICK1 colocalized with both dopamine $D_2$ receptor ($D_2R$) and $D_3R$ in clusters but exerted different functional influences on them. The cell surface expression, agonist affinity, endocytosis, and signaling of $D_2R$ were unaffected by the coexpression of PICK1. On the other hand, the surface expression and tolerance of $D_3R$ were inhibited by the coexpression of PICK1. These findings show that PICK1 exerts multiple effects on $D_3R$ functions.

• The korean journal of orthodontics
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• v.42 no.4
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• pp.169-181
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• 2012

Objective: The purpose of this study was to develop superimposition method on the lower arch using 3-dimensional (3D) cone beam computed tomography (CBCT) images and orthodontic 3D digital modeling. Methods: Integrated 3D CBCT images were acquired by substituting the dental portion of 3D CBCT images with precise dental images of an orthodontic 3D digital model. Images were acquired before and after treatment. For the superimposition, 2 superimposition methods were designed. Surface superimposition was based on the basal bone structure of the mandible by surface-to-surface matching (best-fit method). Plane superimposition was based on anatomical structures (mental and lingual foramen). For the evaluation, 10 landmarks including teeth and anatomic structures were assigned, and 30 times of superimpositions and measurements were performed to determine the more reproducible and reliable method. Results: All landmarks demonstrated that the surface superimposition method produced relatively more consistent coordinate values. The mean distances of measured landmarks values from the means were statistically significantly lower with the surface superimpositions method. Conclusions: Between the 2 superimposition methods designed for the evaluation of 3D changes in the lower arch, surface superimposition was the simpler, more reproducible, reliable method.

• Journal of the Korean Society for Precision Engineering
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• v.24 no.8 s.197
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• pp.97-107
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• 2007

The present CNC machining system if without any CAM software has been limited to 2D or 2.5D plane cut using lines, arcs and curves. If the CNC is equipped with a surface interpolation module and a surface reorganizing module inside it, we can easily try 3D surface machining without aid of CAM software. The existing NURBS surface interpolator is simple and direct to use for a unit surface. However, it enables only machining of each reference surface individually even when machining a simple composite surface. In this paper, we propose a method which can unify and reorganize various reference surfaces with a newly defined NURBS surface cycle command: a multi-repetitive cycle command such as in a CNC turning center. We also introduce a reorganizing rule for reference surfaces using NURBS properties. The usefulness of the proposed method is verified through computer simulation.

• Proceedings of the Korean Society of Precision Engineering Conference
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• 2004.10a
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• pp.1390-1393
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• 2004

In the present industry, three-dimensional colored shape has required for realistic prototype in rapid manufacturing. Z-corporation developed 3D printer which can color three-dimensional prototype but this process can't be adopted to other rapid prototype products and spend much time and cost coloring 3D shape. In this study a new coloring process on three-dimensional surface is proposed for realistic prototype. Three-dimensional surface coloring apparatus is composed of HP ink jet head and X-Y plotter. Distance and angle between ink jet nozzle and 3D surface are set as process parameter. Based on the experiment of process parameters, it is shown that distance and angle affected on printed image on 3D surface. Circle and line shape are chosen as standard image shape because the shape has widely used as standard in 2D printing. Consequently, the distorted image on 3D surface is corrected by transformed input image data.

• Proceedings of the Korean Vacuum Society Conference
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• 2000.02a
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• pp.156-156
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• 2000

Recently, the surface electronic states have attracted much attention since their standing wave patterns created around steps, defects, and adsorbates on noble metal surfaces such as Au(111), Ag(110), and Cu(111) were observed by scanning tunneling microscopy (STM). As a typical example, a striking circular pattern of "Quantum corral" observed by Crommie, Lutz, and Eigler, covers a number of text books of quantum mechanics, demonstrating a wavy nature of electrons. After the discoveries, similar standing waves patterns have been observed on other metal and demiconductor surfaces and even on a side polane of nano-tubes. With an expectation that the surface states could be utilized as one of ideal cases for studying two dimensionakl (sD) electronic system, various properties, such as mean free path / life time of the electronic states, have been characterized based on an analysis of standing wave patterns, . for the 2D electron system, electron density is one of the most importnat parameters which determines the properties on it. One advantage of conventional 2D electron system, such as the ones realized at AlGaAs/GaAs and SiO2/Si interfaces, is their controllability of the electrondensity. It can be changed and controlled by a factor of orders through an application of voltage on the gate electrode. On the other hand, changing the leectron density of the surface-state 2D electron system is not simple. On ewqy to change the electron density of the surface-state 2D electron system is not simple. One way to change the electron density is to deposit other elements on the system. it has been known that Pd(111) surface has unoccupied surface states whose energy level is just above Fermi level. Recently, we found that by depositing Pd on Cu(111) surface, occupied surface states of Cu(111) is lifted up, crossing at Fermi level around 2ML, and approaches to the intrinsic Pd surface states with a increase in thickness. Electron density occupied in the states is thus gradually reduced by Pd deposition. Park et al. also observed a change in Fermi wave number of the surface states of Cu(111) by deposition of Xe layer on it, which suggests another possible way of changing electron density. In this talk, after a brief review of recent progress in a study of standing weaves by STM, I will discuss about how the electron density can be changed and controlled and feasibility of using the surface states for a study of 2D electron system. One of the most important advantage of the surface-state 2D electron system is that one can directly and easily access to the system with a high spatial resolution by STM/AFM.y STM/AFM.

• Journal of the Korean Society of Visualization
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• v.21 no.2
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• pp.55-62
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• 2023

The characteristic of jet impinging on the concave surface were analyzed through thermographic phosphor thermometry (TPT) and numerical investigation. Under a jet Reynolds number of 6600, nozzle diameters and nozzle-to-surface distances (H/d) were changed 5mm and 10mm and H/d=2 and 5. The RNG k-ε turbulence model can accurately predict the distribution of Nusselt number, compared to other models (SST k-ω, realizable k-ε). Heat transfer characteristics varied with the nozzle diameter and H/d, with a secondary peak noted at H/d =2, due to vortex-induced flow detachment and reattachment. An increase in nozzle diameter enhanced jet momentum, turbulence strength, and heat transfer.

• Journal of the Ergonomics Society of Korea
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• v.24 no.2
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• pp.85-91
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• 2005

To understand the basic relationship between 3D curved surface model and 2D pattern, simplified torso model was generated by commercial CAD program (IDEAS). 3D torso model was then divided into different blocks and unfolded into a flat pattern as in ordinary works of clothing item design. As results, 2D pattern development of different part of 3D torso model was attempted and analyzed mathematically. It was found that different height, radius and tangent slope of 3D blocks resulted in different 2D pattern. The relationships between the shape parameters of 3D torso blocks and those of 2D patterns were analyzed using regression equations. Direct way of drawing a 2D pattern of corresponding 3D torso block was also illustrated for the convenience of pattern making using conventional measurements of upper/ lower radii and height of 3D torso block.

• International Journal of CAD/CAM
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• v.8 no.1
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• pp.21-28
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• 2009

In the present work, an attempt has been made to construct branching surface from 2-D contours, which are given at different layers and may have branches. If a layer having more than one contour and corresponds to contour at adjacent layers, then it is termed as branching problem and approximated by adding additional points in between the layers. Firstly, the branching problem is converted to single contour case in which there is no branching at any layer and the final branching surface is obtained by skinning. Contours are constructed from the given input points at different layers by energy-based B-Spline approximation. 3-D curves are constructed after adding additional points into the contour points for all the layers having branching problem by using energy-based B-Spline formulation. Final 3-D surface is obtained by skinning 3-D curves and 2-D contours. There are three types of branching problems: (a) One-to-one, (b) One-to-many and (c) Many-to-many. Oneto-one problem has been done by plethora of researchers based on minimizations of twist and curvature and different tiling techniques. One-to-many problem is the one in which at least one plane must have more than one contour and have correspondence with the contour at adjacent layers. Many-to-many problem is stated as m contours at i-th layer and n contours at (i+1)th layer. This problem can be solved by combining one-to-many branching methodology. Branching problem is very important in CAD, medical imaging and geographical information system(GIS).

• Tribology and Lubricants
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• v.40 no.2
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• pp.47-53
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• 2024

Surface topography plays a decisive role in determining the performance of several precision components. In particular, the surface roughness of semiconductor devices affects the precision of the circuit. In this regard, the surface topography of a given surface needs to be appropriately assessed. Typically, the average roughness is used as one of the main indicators of surface finish quality because it is influenced by both dynamic and static parameters. Owing to the increasing demand for such accurate and reliable surface measurement systems, studies are continuously being conducted to understand the parameters of surface roughness and measure the average roughness with high reliability. However, the differences in the measurement methods of surface roughness are not clearly understood. Hence, in this study, the surface roughness of the back of a silicon wafer was measured using both contact and noncontact methods. Subsequently, a comparative analysis was conducted according to various surface roughness parameters to identify the differences in surface roughness depending on the measurement method. When using a 3D laser confocal microscope, even smaller surface asperities can be measured compared with the use of a 3D profiler. The results are expected to improve the understanding of the surface roughness characteristics of precision components and be used as a useful guideline for selecting the measurement method for surface topography assessment.

• Korean Journal of Air-Conditioning and Refrigeration Engineering
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• v.11 no.6
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• pp.846-854
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• 1999

Measurements of the local heat transfer coefficients were made on a hemispherically convex surface with a round oblique impinging jet. The liquid crystal transient method was used for these measurements. This method, which is a variation on the transient method, suddenly exposes a preheated wall to an impinging jet while video recording the response of liquid crystal for the surface temperature measurements. The Reynolds number used was 23000 and the nozzle-to-surface distance was L/d=2, 4, 6, 8, and 10 and the jet angle was $\alpha$=$0^{\circ}\; 15^{\circ}\;30^{\circ}C\; and \;40^{\circ}C$. In the experiment, the Nusselt number at the stagnation point decreases as the jet angle increases and has the maximum value for L/d=6. The X-axis Nusselt number distributions exhibit Secondary maxima at $0^{\circ}C\re $\alpha$\re 15^{\circ}C, L/d\le6$ for X/d＜0(upstream) and at $0^{\circ}C\re $\alpha$40^{\circ}C,\;L/d\le4\;and\; at\; 30^{\circ}C\re $\alpha$$\leq$40^{\circ}C,\;L/d\le 6 $for X/d＞0(downstream). The secondary maxima occurs at long distance from the stagnation point as the jet angle increases or the nozzle-to-surface distance decreases. The Y-axis Nusselt number distributions exhibit secondary maxima at Y/d=$\pm$2 for $0^{\circ}C\le a\le30^{\circ}C\; and\; L/d\le4, and \;for\;$\alpha$=40^{\circ}C$and L/d=2. The displacement of the maximum Nusselt number from the stagnation point increases as the jet angle increases or the nozzle-to-surface distance decreases and the maximum distance is about 0.67 times of the nozzle diameter. The ratio of the maximum Nusselt number to the stagnation Nusselt number increases as the jet angle increases.