• The Journal of Bigdata
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• v.6 no.2
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• pp.109-124
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• 2021

In this paper, the structural characteristics of Industry-University cooperation networks are analyzed using network analysis. Recent studies have shown that technological cooperation and joint research has a positive effect on R&D performance. In order to boost innovation performance, various types of cooperative activities and governmental policy supports for major R&D stakeholders(i.e. universities, laboratories, etc.) are provided. However, despite these efforts, the outcome is still insufficient, so it is time to prepare for a plan to build an innovative network to strengthen university-centered Industry-University cooperation activities. Specifically, this study builds the networks according to the form of Industry-University cooperations(i.e. patent, paper, joint research, and technology transfer), and different types of Industry-University cooperation networks are analyzed from a statistical viewpoint by using QAP correlation and regression analyses. The analysis results show that joint research network is closely related to paper network, and is related to other Industry-University cooperation networks. This study is expected to shed a light on supporting innovation activities such as establishing Industry-University cooperation strategies and discovering cooperative partners necessary for creating new growth engines for universities.

• Journal of Industrial Convergence
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• v.18 no.5
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• pp.30-35
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• 2020

The purpose of this study is to find out the effect of aerobic exercise through convergence on exhaled carbon monoxide and cardiorespiratory function of female college students who participated in nonsmoking. The subjects were female college students from University D in Metropolitan City D, and those who started smoking 2 years ago and who do not engage in regular physical activities were first selected, and a total of 18 people who indicated their intention to participate in the experiment were selected to receive a pledge of nonsmoking and consent to the experiment. The selected subjects were classified into 9 people in the exercise group and 9 in the control group by wireless assignment, and individual exercise intensity was set through the maximum exercise load test to establish an accurate exercise program. Individual exercise intensity is set to 50%HRmax for 1-3 weeks, 60%HRmax for 4-6 weeks, 70%HRmax for 7-9 weeks. In order to apply the correct exercise intensity during exercise, a Polar heart rate monitor was used for control and the following results were obtained. First, the change in carbon monoxide decreased by three levels from 21.17±3.67ppm (Red 2 16-25ppm, habitual smokers) before participation in the exercise group that participated in aerobic exercise for 9 weeks to 1.36±0.76ppm (Green, 0-6ppm, non-smokers) after participation, and the control group also showed the same effect from 22.35±2.08ppm (Red 2 16-25ppm, habitual smokers) to 2.81±0.51ppm (Green, 0-6ppm, non-smokers). Second, the change in cardiorespiratory function showed a significant increase in all of the maximum oxygen intake, maximum heart rate, and maximum ventilation in the exercise group who participated in aerobic exercise for 9 weeks, but there was no significant change in the control group. Therefore, aerobic exercise showed the effect of improving the cardiorespiratory function by releasing carbon monoxide and supplying sufficient oxygen to various organs.

• Proceedings of the Korean Society for Bioinformatics Conference
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• 2005.09a
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• pp.173-182
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• 2005

A three dimensional (3D) model for the catalytic region of Type II Pseudomonas sp. USM 4-55 PHA synthase 1 (PhaC1$_{P.sp\;USM\;4-55}$) from residue 267 to residue 484 was developed. Sequence analysis demonstrated that PhaC1$_{P.sp\;USM\;4-55}$ lacked homology with all known structural databases. PSI-BLAST and HMM Superfamily analyses demonstrated that this enzyme belongs to the ${\alpha}/{\beta}$ hydrolase fold family. Threading approach revealed that the most suitable template to use was the Human gastric lipase (1HLG). The superimposition of the predicted PhaC1$_{P.sp\;USM\;4-55}$ model with the 1HLG template structure covering 86.2% of the backbone atoms showed an RMSD of 1.15 ${\AA}$ The catalytic residues comprising of Cys296, Asp451, His452 and His479 were found to be conserved and were located adjacent to each other. We proposed that the catalytic mechanism involved the formation of two tetrahedral intermediates.

• Journal of the Korean Magnetic Resonance Society
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• v.6 no.1
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• pp.78-83
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• 2002

A new fluoroquinolone (DW-116) with a broad antibacterial spectrum was synthesized by introducing functional fluoropyridyl and methylpyrazine groups on N1, C7 position of quinolone moiety, respectively. $^{1}$H and $^{13}$ C NMR signal assignments and structure were completely elucidated by 2D-NMR methods. Physicochemical properties of products were also investigated. DW-116 is decomposed at 306.9$^{\circ}C$ and the decomposition starts at around 285$^{\circ}C$. The free base form is melt at 280.7$^{\circ}C$ and started to be decomposed immediately. DW-116 has two kinds of polymorphism which is important in drug action but these two plate and rod types have the same solubility in water. However the solubility is quite different in less or polar solvent. The plate type is more soluble in less polar solvent except in dichloromethane.

• Journal of Korean Society of Transportation
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• v.17 no.5
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• pp.99-110
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• 1999

This study deals with the adaptability questions of O-D table estimation models. Its objectives are two-fold; (1) to estimate the characteristics of various O-D table estimation models(i.e. linear regression models. entropy models and statistic models) and (2) to find the model which estimates the O-D table with the best accuracy under the various data conditions. In Pursuing the above, this study gives the particular attentions to the test of the models, using the Sioux Falls network and equilibrium assignment method of MINUTP. The major findings are the followings. Firstly. it finds that the statistic models have the most goodness of fat among all models, if the required data are all Prepared. But it Presents that statistic models are the most sensitive against the underspecification and inconsistency problems of link data. Secondly, It shows that the linear regression models have the worst goodness of fat among all models. But the linear regression models are the most insensitive to the underspecification and inconsistency problems. Thirdly, THE/1 model of entropy model is sensitive against the underspecification and incon-sistency problems, but THE/2 model is insensitive. Finally, other informations like total volume, zonal Production and attraction volumes in 0-D table, help models to gain the better goodness of fit. Especially, in the statistic models. both the zonal production and attraction volume data are helpful to estimate the link volumes. It can be expected that the results dive some implications not only to the selection of optimal model under the various given data, but also to the development or modification of model.

• Proceedings of the Korean Society for Applied Microbiology Conference
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• 1986.12a
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• pp.505.2-506
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• 1986

L-Azetidine-2-carboxylic acid (A-2-C), a four-membered cyclic imino acid has been identified in certain plants, and the microorganism Actinoplanes ferrugineus. The imino acid A-2-C has a physiological significance as an antgaonist of proline during peptide synthesis. The biosynthetic mechanism for the formation of A-2-C has not been studied in any detail. By using various amino acids such as methionine and S-adenosyl-L-methionine labeled with deuterium or carbon-14, the details of the biosynthetic pathway and a possible mechanism for the formation of L-A-2-C in .4. ferrugineus have been unravelled, Both in vivo and in vitro experimental results suggest the biosynthesis of L-A-2-C is mediated by a confactor containing a carbonyl group, probably pyridoxal Phosphate. S-Adenosyl-L-methionine, which seems to be the direct biosynthetic substrate, has undergone a f-displacement by an ${\alpha}$-amino group of the amino acid portion of the substrate S-adenosyl-L-methionine potentially via a vinylglycine intermediate. The overall stereochemical events at the ${\beta}$-carbon of the substrate have been shown to inversion of configuration. The overall stereochemical events at the -position of the sub- strate have also been shown to occur with inversion of configuration. The ${\beta}$, ${\gamma}$-elimination reaction of the substrate seems to follow a cisoidal-type mechanism and the addition portion of the reaction a transoidal-type mechanism . The assignment of the proton NMR of A-2-C has been deduced by apply- ing NOE difference experiments, Gd(III) line-broadening experiments and 2D-NOESY experiments of regio-and stereospecificially deuterated A-2-C's.

• Journal of the Institute of Electronics Engineers of Korea TC
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• v.45 no.11
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• pp.45-54
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• 2008

In this paper, we use particle swarm optimization (PSO) to design a randomly excited and randomly spaced linear array with either the lowest side lobe level (SLL) or the narrowest beamwidth. The positions and the excitation amplitudes of the array elements are considered as variables to be controlled. The beam pattern is optimized by controlling the two variables simultaneously and randomly. The best beam patterns are obtained using PSO in the fitness function where performance is improved by the random assignment of weight coefficients to each angular sector of the beam Pattern. The weight coefficients and angles are obtained through several trial runs. Also, an extra term, ${\beta}{\ast}BW$, is added to the fitness function to account for the beamwidth as well as the SLL. Is produces the best result for the beam pattern with either the lowest SLL or the narrowest beamwidth. In the former case, the SLL and beamwidth are about -43dB and $32.2^{\circ}$, respectively, with only 10 elements. In the latter case, the SLL and beamwidth are about -26dB and $24.2^{\circ}$, respectively.

• Journal of Korean Society of Transportation
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• v.32 no.4
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• pp.303-314
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• 2014

This study develops a $CO_2$ emissions estimation method, which considers different O/D travel patterns and through traffic volumes, in different regions for $CO_2$ emissions management in the field of transportation. In the research, O/D and network data provided by the Korea Transport Database (KTDB) Center are used as basic data. The results show that the total emission was similar to the Metropolitan's total emission which was estimated by KTDB (2009). With the analysis focusing on Gyeonggi-do, the results show that $CO_2$ emission from through traffic volumes was greater than $CO_2$ emissions of the Intra-Regional in southern regions; By contrast, $CO_2$ emissions of the Intra-Regional was greater than that from through traffic volumes in northern regions. Therefore, the $CO_2$ emissions management needs to be segregated into local government and nation with each travel pattern.

• Asian-Australasian Journal of Animal Sciences
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• v.16 no.7
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• pp.946-951
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• 2003

The Genetic diversity and relationship of native Siri (Bos indicus) cattle populations of Bhutan were evaluated using 20 microsatellite markers. A total of 120 Siri cattle were sampled and were grouped into four populations according to their geographical locations which were named Siri West, Siri South, Siri Central and Siri East cattle. For each, 30 individuals were sampled. In addition, 30 samples each of Indian Jaba (B. indicus), Tibetan Goleng (B. taurus), Nepal Hill cattle (B. indicus), Holstein Friesian (B.taurus) and Mithun (B. frontalis) were typed. The mean number of alleles per loci (MNA) and observed heterozygosity (Ho) were high in the Siri populations ($MNA=7.2{\pm}0.3$ to $8.9{\pm}0.5$ and $Ho=0.67{\pm}0.04$ to $0.73{\pm}0.03$). The smallest coefficient of genetic differentiation and genetic distance ($F_{ST}=0.015$ and $D_A=0.073$) were obtained between Siri West and Siri Central populations. Siri East population is genetically distinct from the other Siri populations being close to the Indian Jaba ($F_{ST}=0.024$ and $D_A=0.084$). A high bootstrap value of 96% supported the close relationship of Siri South, Siri Central and Siri West, while the relationship between Siri East and Jaba was also supported by a high bootstrap value (82%). Data from principal component analysis and individual assignment test were in concordance with the inference from genetic distance and differentiation. In conclusion we identified two separate Siri cattle populations in Bhutan at the genetic level. One population included Siri cattle sampled from the West, Central and South of the country and the other Siri cattle was sampled from the East of the country. We suggest that Siri cattle conservation program in Bhutan should focus on the former population as it has received less genetic influence from other cattle breeds.

• KSCE Journal of Civil and Environmental Engineering Research
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• v.2 no.3
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• pp.33-41
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• 1982

Development is given for an analytical approach that can investigate parameters characterizing road network geometry. A grid transportation network having a hierarchy structure is considered on a homogeneous and isotropic urban plane in which trip origins and destinations are uniformly dispersed and the trip length distribution is independent of the location of the origin. The object is to find the optimal spacings between urban arterials so as to minimize the sum of travel and construction costs, subject to the hypothesis that a trip assignment follows the Wardrop's first principle. The proposed approach is not the genera method for determining an efficient network layout, but can be used as basic concept for generating and evaluating urban road network alternatives. Given an O-D table and cost estimates the approach is able to outline at least in a qualitative sense the optimal spacings of urban arterial roads.