• The Korean Journal of Pharmacology
• /
• v.26 no.1
• /
• pp.67-76
• /
• 1990

Hydrocortisone 50 mg/kg (HC), dehydroepiandrosterone 250 mg/kg (DHEA), ${\beta}-estradiol$ 5 mg/kg (E2), and testosterone 20 mg/kg (TS) were subcutaneously injected into the castrated ICR mice at noon for four days, and the animals were sacrificed at 10-12 A.M. of the fifth day. The intestinal DAO activity was significantly decreased by HC, but it was rather increased by E2 and TS, respectively. And DHEA did not change the DAO activity. But the hepatic MAO activity was not affected by anyone of HC, DHEA, E2, and TS. Aminoguanidine 25 mg/kg produced the marked decrease of the intestinal DAO activity and the significant increases of the intestinal PT and SD contents, but it did not change the hepatic polyamine contents. HC and DHEA induced the significant increase of the intestinal PT content. E2 induced the marked increase of the hepatic PT content and the moderate increase of the intestinal PT content. TS little affected the polyamine contents of the liver and intestine. These results suggest that the E2-induced increase of the hepatic PT content is rather ascribed to the greater enhancement of PT synthesis than the inhibition of polyamine catabolism, and that the HC-induced increase of the intestinal PT content is due partly to the inhibition of polyamine catabolism via DAO.

• Resources Recycling
• /
• v.22 no.5
• /
• pp.43-49
• /
• 2013

Froth flotation was performed to remove As from the tailing of Sangdong Mine. When the tailings of Sangdong Mine were analyzed by the Standard Method for the Soil Environment Conservation, the concentration of As was found to be at a serious level (282 mg/kg), exceeding countermeasure standard (75 mg/kg). Froth flotation was performed to remove As and preliminary tests were performed to select the reagents. Specifically, froth flotation was performed using collector and frother, KAX and DF250 respectively. An experiment based on pH changes found that the removal rate was highest at pH6. The removal rate of As was highest at agitating rate 1500 according to the agitating rate. In the experiment based on the quantities of KAX added, the removal rate of As was found to be highest at 300 g/ton and was reduced at higher levels than 300 g/ton. An experiment based on pulp density found that the removal rate was highest at pulp density 30%. It was possible to adjust the As level -- which exceeded countermeasure standard (75 mg/kg) -- to 22.5mg/kg to satisfy the Warning standard (25 mg/kg), from the results of froth flotation.

• Korean Journal of Plant Resources
• /
• v.27 no.2
• /
• pp.111-118
• /
• 2014

Contents of phenolics, flavonoids, and catechins, and antioxidant activity were investigated in the ethanol extracts of three different flower species, Magnolia denudata, Prunus mume, Carthamus tinctorius. Total phenolics were more present in M. denudata than P. mume or C. tinctorius, ranging from 72.6 to 118.0 mg/kg (p < 0.05). Total flavonoids level had same tendency to total phenolics content, showing highest amount (25.1 mg/kg) in M. denudata. The antioxidant activity of the methanol extracts from all the flowers dose-dependently increased. DPPH free radical scavenging activity at 250 mg/kgwas higher in M. denudata and P. mume by 93.0 and 92.6%, respectively, than C. tinctorius by 23.0% (p < 0.05). Total catechins content including 6 compounds was higher in M. denudate (9,425.5 mg/kg) than that in P. mume or C. tinctorius (3,407.8 or 190.6 mg/kg). However, P. mume extracts showed highest amount in caffeine as well as vitamine C. DPPH radical scavenging activity in three different flowers was highly correlated with contents of total phenolics ($r^2=0.7994$), total flavonoids ($r^2=0.9131$), and total catechins ($r^2=0.5929$), and their content and activities were different depending on species.

• Korean Journal of Ichthyology
• /
• v.34 no.4
• /
• pp.253-261
• /
• 2022

After exposing Olive flounder and Korean rockfish to the concentration ranges of control (0 mg/L), 100 mg/L, 250 mg/L, 500 mg/L, and 1,000 mg/L, to investigate the physiological properties of suspended load on fish AST/GOT, ALT/GPT, ALP and cortisol were analyzed. As a result of the analysis, the AST/GOT, ALT/GPT, ALP and cortisol values were higher in the suspended load concentration section than in the control group. After artificial infection with S. parauberis for Olive flounder and V. harveyi for Korean rockfish exposed to suspended load, the survival rate was higher in the control group than in the suspended load concentration section. These results are related to the previously study results of suspended load that adversely affect fish, suggesting that suspended load affects the health of fish.

• Proceedings of the Korean Society of Applied Pharmacology
• /
• 1996.04a
• /
• pp.200-200
• /
• 1996

간재생 및 만성 간질환모델에 대한 인진호 추출분획의 간장 약효검색 방법 1. 간세포 재생능력에 대한 효과 : SD계 수컷 흰쥐(체중 300-350g)를 마취하에서 복부정중선을 따라 개복후 간의 중앙엽 및 좌측엽을 절제하여 봉합하고 수술조작을 끝낸 추 4시간, 익일부터 7일간 오후 5시에 약물을 경구투여하고 마지막투여 후 20시간 절식, 부검하여 간재생률 및 BSP 정체율을 측정하였다. 2. $CCl_4$ 만성간장해 모델에 대한 효자 SD계 수컷 흰쥐(체중 200-250g)에 $CCl_4$ : olive oil 40%용액을 0.5 $m\ell$/kg b.wt. 용량으로 6일간 결구투여 한 후 7일째부터 매일 시험약물을 $CCl_4$ 혼합액 투여 4시간전 및 4시간후에 2회 경구투여하였으며 이 조작을 8일간 하고 마지막 투여 24시간 후에 부검하여 혈액내 ALT 및 AST치, 간조직내 total protein, triglyceride 및 hydroxyproline 양을 측정하였으며, 간중량도 측정하였다. 3. 약물투여 음성대조 : 1% CMC-Na 용액(10$m\ell$/kg b.wt.) 양성대조 : silymarin(25mg/kg), DDB(37.5mg/kg) 인진호추출분획 : KP(180mg/kg), PS-1(300mg/kg), PS-2(300mg/kg), EE (500mg/kg ), HH(640mg/kg), BE(1500mg/kg)

• Journal of Korean Society of Water and Wastewater
• /
• v.27 no.6
• /
• pp.779-785
• /
• 2013

This study investigated the applicability of a two step microfiltration(MF) and reverse osmosis(RO) membrane system for reuse of tunnel wastewater. In this two step process, the MF system first treated only micropollutants in tunnel wastewater such as suspended solids(SS) and heavy metals, achieving less than 0.2 NTU turbidity, less than 1.1 mg/L chemical oxygen demand($COD_{Mn}$) and less than 0.8 mg/L total manganese(Mn). The RO system then removed over 95 % of the remaining pollutnats and particles, resulting in less than 0.02 NTU turbidity, less than 0.5 mg/L chemical oxygen demand($COD_{Mn}$), less than 0.04 mg/L total nitrogen(T-N) and less than 0.01 mg/L total phosphorus(T-P). In particular, addition of an RO system could lead to markedly reduced high salt concentrations in tunnel wastewater, approaching almost zero. Thus, reclaimed water using the combined membrane system could satisfy current South Korean regulations concerning wastewater reuse(turbidity ${\leq}2.0$ NTU; T-N ${\leq}10mg/L$; T-P ${\leq}0.5mg/L$; Salinity ${\leq}250mg{\cdot}Cl/L$).

• Proceedings of the Korean Vacuum Society Conference
• /
• 2011.08a
• /
• pp.188-188
• /
• 2011

MgO는 암염구조의 이온결합성 화합물로 7.8 eV의 높은 띠 틈과 약 95%의 탁월한 투과도를 갖는다. 또한, ${\gamma}$ process에 의한 이차 전자 방출이 높고 이온 스퍼터링에 의한 표면 손상이 적어 면 방전 AC-PDP의 보호막으로 이용된다. 따라서 MgO 보호막에 관한 연구는 이차 전자 방출 계수를 높여 방전 전압을 감소시키고 높은 유전율과 투과도를 유지시키기 위한 목적으로 전개되어지고 있다. 본 연구는 이온 스퍼터링에 의한 MgO 보호막의 표면 특성의 변화를 알아보기 위해 이루어졌다. MgO 박막은 electron beam evaporation의 방법을 통해 챔버 내에 O 기체를 주입하고 P type Si 기판을 300$^{\circ}C$ 가열하여 40 nm 두께로 제작되었다. 박막 시료는 표면분석 전 초고진공챔버 내에서 표면에 산화된 불순물 제거를 위해 550$^{\circ}C$의 열처리가 되어졌다. 그리고 250 eV의 He 이온으로 박막 표면을 스퍼터링 하여 XPS, REELS, UPS를 이용하여 전자 및 광학적 특성을 연구하였다. XPS 분석을 통해 MgO 박막은 He 이온 스퍼터링에 의해 표면의 화학적 조성이 변하지 않는다는 것을 확인했다. MgO 박막에 이온 스퍼터링을 하면 표준 시료와 비교하여 Ep=1,500 eV일 때 7.54 eV에서 7.63 eV로 높아지는 경향이 있다. 일함수는 He 이온 스퍼터링 한 결과 3.85 eV로부터 4.09 eV로 약간 높아졌다. 또한, QUEELS simulation으로 얻은 가시광 투과도는 91~92%로 분석되었다.

• Fisheries and Aquatic Sciences
• /
• v.4 no.4
• /
• pp.252-256
• /
• 2001

In this study, the bactericidal activity of each extract from Sawa-wasabi (Wasabia japonica) root, stem and leaf against the fish pathogenic bacteria were examined. The main component related to bactericidal activity in Sawa-wasabi was well known to AlT. The Sawa-wasabi roots showed the highest AIT amount with 1.18 mg/g. Stems was 0.41 and leaves was 0.38 mg/g. All of them showed bactericidal activity against 2 strains of Vibrio hollisae, V. anguillarum, and 2 strains of Edwardsiella tarda, but weak effect against Staphylococcus capitis. The Sawa­wasabi leaves showed the strongest bactericidal activity with minimal bactericidal concentrations (MBCs) of 156.3mg of dry weight/mL against 2 strains of V. hollisae, V. anguillarum and 2 strains of E. tarda. The roots and stems showed a little weak bactericidal activities with 312-1,250mg of dry weight/mL against them. These results suggest that certain components besides AIT in Sawa-wasabi are affective in killing fish pathogenic bacteria.

• Journal of the Korea Organic Resources Recycling Association
• /
• v.10 no.1
• /
• pp.102-108
• /
• 2002

The effects of ammonia on mesophilic anaerobic digestion were investigated by operating lab-scale two-stage ASBF reactors using swine wastewaters as influent without and with ammonia removal at HRT of 1-2 days and OLR of $2.2{\sim}9.6kg-COD/m^3{\cdot}d$ for 250 days. The COD removal efficiency and biogas generation of two-stage ASBF reactors was decreased by increasing influent ammonia concentrations to 1,580 mg(T-N)/L with increasing OLR to $6.3kg-COD/m^3{\cdot}d$, while those were increased by maintaining influent ammonia concentrations below 340 mg(T-N)/L by MAP precipitation with increasing OLR to $9.6kg-COD/m^3{\cdot}d$. Initial inhibirion of ammonia on anaerobic processes was observed at a concentration of 760 mg(T-N)/L and the COD removal efficiency and biogas generation dropped to 1/2 at ammonia concentration ranges of 1,540~1,870 mg(T-N)/L. It is essential to remove ammonia in swine wastewaters to an initial inhibition level before anaerobic processes for the effective removal of COD.

• YAKHAK HOEJI
• /
• v.41 no.2
• /
• pp.255-259
• /
• 1997

Effects of the aqueous extract of Aquilariae Lignum (Thymelaeaceae) on the allergic reactions were investigated. Oral administration of this extract (50, 250, and 500mg/kg) exhi bited a dose-dependent inhibition on passive cutaneous anaphylactic reactions in rats. Administrations of this extract (500mg/kg, i.p.) at 60 min before and 5, 10 min after the compound 48/80 treatment (8mg/kg, i.p.) decreased the mortality rates to 0, 0, and 14.2%, respectively. The aqueous extract of Aquilariae Lignum (0.05 ~ 1.6mg/ml) showed a dose-related inhibition on histamine release from rat peritoneal mast cells. The morphological examination also clearly showed that the aqueous extract of Aquilariae Lignum prevented the degranulation of mast cells in rats.