• Bulletin of the Korean Chemical Society
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• v.7 no.2
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• pp.116-120
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• 1986

Irradiation of 1,4-diphenyl-1,3-butadiyne and 5,5-dimethyl-1-phenyl-1,3-hexadiyne with methanol yields 1:1 polar addition products, [E]- and [Z]-1,4-diphenyl-1-methoxy-1-buten-3-yne and [E]- and [Z]-5,5-dimethyl-1-methoxy-1-phenyl-1-hexen-3-yne, respectively. These geometrical isomers were converted into each other reaching the photostationary state on irradiation with 300 nm UV light. The photoaddition reaction of 1,4-diphenyl-1,3-butadiyne and 5,5-dimethyl-1-phenyl-1,3-hexadiyne with methanol seems to proceed from the zwitterionic lowest excited state.

• Archives of Pharmacal Research
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• v.26 no.11
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• pp.902-905
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• 2003

Five compounds of terpenoids and coumarins were isolated from the non-polar fraction of Artemisia apiacea by open column chromatography. Their structures were elucidated as $\alpha$-amyrin (1), $\beta$-amyrin (2), $\beta$-sitosterol (3), 5,6,7-trimethoxycoumarin (4) and 6-methoxy-7,8-methylenedioxycoumarin (5) by chemical and spectroscopic analysis. This is the first report of the isolation of $\alpha$-amyrin, $\beta$-amyrin, 5,6,7-trimethoxycoumarin and 6-methoxy-7,8-methylene-dioxycoumarin from this plant.

• Archives of Pharmacal Research
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• v.20 no.1
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• pp.88-90
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• 1997

Two compounds were newly isolated from the leaves of Aloe barbadensis Mill. Their strucutres were identified as 3, 4-dihydro-3, 9-dihydroxy-8-methoxy-3-methyl-1(2H)-anthracenone(1) and 10-.betha.-D-glucopyranosyl-1, 80, 10-trihydroxy-3-(hydroxymethyl)-(R)-9(10H)-anth racenone(2) by chemical and spectral evidences.

• Food Engineering Progress
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• v.14 no.4
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• pp.292-298
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• 2010

Wheat germ contains the glycosylated forms of 2-methoxy-p-benzoquinone (2-MBQ) and 2,6-dimethoxy-p-benzoquinone (2,6-DMBQ), both of which have antimicrobial and immunostimulatory effects. Conversion of glycosylated 2-MBQ and 2,6-DMBQ to their more functional unglycosylated forms requires enzymatic action of $\beta$-glucosidase. We investigated the applications of lactic acid bacteria and yeast that produce $\beta$-glucosidase as starters for production of unglycosylated 2-MBQ and 2,6-DMBQ from wheat germ. Lactobacillus zeae and Pichia pijperi were selected through $\beta$-glucosidase enzyme assays for 37 yeast strains and five strains of lactic acid bacteria. Lb. zeae was more efficient than P. pijperi at producing 2-MBQ and 2,6-DMBQ from wheat germ. After 48 hr of fermentation with a mixed culture of Lb. zeae and P. pijperi, the concentration of 2-MBQ was 0.46${\pm}$0.07 mg/g, indicating an approximately 1.6-fold higher concentration than that obtained by pure culture of Lb. zeae. However, the concentration of 2,6-DMBQ was not significantly enhanced by fermentation with a mixed culture of Lb. zeae and P. pijperi.

• Membrane Journal
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• v.20 no.2
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• pp.135-141
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• 2010

Various asymmetric Polysulfone membranes were prepared for a MBR process. Ether-typed alcohols (co-solvent) were added into a dope solution in order to control the pore size of membrane, whose effect on water permeability were investigated. Pore size of the prepared membranes were more affected by molecular-structure of co-solvent than by boiling point of theirs. With the increasing order of methoxy ($CH_3$-O-) < secondary propanol ($-CH_2$-CH(OH)$-CH_3$) < ethoxy ($CH_3-CH_2$-O-), water permeability of the prepared membrane increased. The phenomenon might attribute to the difference of molecularly steric hinderance of co-solvent (eg, Methoxy propanol, Ethoxy ethanol, Methoxy ethanol) in dope solution during the phase inversion. By the addition of ether typed alcohol into a dope solution, the pore size of MF (microfiltration) could be controlled. Also, Membrane prepared was applied to a MBR process and the system was stably operated for 2 months.

• Journal of the Korean Wood Science and Technology
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• v.43 no.2
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• pp.274-285
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• 2015

In view of the environmental and health hazards posed by synthetic insecticides, the use of plant products as botanical insecticides has gained increasing in recent years. In this study, we reported the insecticidal activity of extracts isolated from Coptis chinensis. On crude extraction, among the various solvent types tested (water, 1% (w/v) of sodium hydroxide, 70% ethanol), the 70% ethanol extract showed the best insecticidal activity (36.5%). Three different fractions (n-hexane, chloroform and ethyl acetate) were obtained from crude extract (70% ethanol) of the chloroform fraction and found to have noteworthy insecticidal activity (62.9%) by filter paper contact bioassay. Their chemical structures were identified as 2-methoxy-4-vinylphenol and aniline by head space-GC-MS analysis. Both compounds displayed a dose-dependent insecticidal activity of Myzus persicae (Sulzer). Insecticidal activity at the lowest concentration tested (500 ppm) approached 85.4% in the aniline compared with 79.9% in the 2-methoxy-4-vinylphenol. The insecticidal activity was greater for the aniline than 2-methoxy-4-vinylphenol. It is believed that the insecticidal activity is due mainly to the presence of aniline.

• Journal of the Korean Wood Science and Technology
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• v.51 no.4
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• pp.283-294
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• 2023

Chemical characterization of vinegars obtained from Durian wood (Durio sp.) and their termicidal activity against Coptotermes curvignathus and antifungal activity against Schizophyllum commune were evaluated. The process of pyrolysis produced wood vinegars at three distinct temperature: 350℃, 400℃, and 450℃. To determine their effectiveness against fungal growth, the vinegars were tested using a Petri dish with 1.0%, 2.0%, 3.0%, and 4.0% (v/v) against S. commune. In the experiment, termicidal activities were evaluated using a no-choice test for C. curvignathus with 3.0%, 6.0%, 9.0%, and 12.0% (v/v). The wood vinegar exhibited antitermitic activity to C. curvignathus workers in the no-choice experiment; For vinegar produced at 450℃, a 6% concentration was required to achieve 100% mortality against C. curvignathus. In addition, a 12% vinegar produced at 450℃ resulted in the lowest mass loss of treated filter paper, which was 20.00%. Furthermore, all the wood vinegars exhibited antifungal activities against S. commune at concentration of 2.0%. The dominant chemical components of wood vinegar produced at temperature of 350℃, 400℃, and 450℃ were 2-methoxy-phenol, 4-ethyl-2-methoxy-phenol, 4-ethyl-2-methoxy-phenol, 3.5-dimethoxy-4-hydroxytoluene, and creosol.

• Archives of Pharmacal Research
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• v.12 no.1
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• pp.12-16
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• 1989

6-Formyl-5-methoxy-2-methyl chromone derivatives condensed with 2-thiox-4-imidazolinone derivatives to form the corresponding '10-methoxy-7-methyl-3-thioxo-chromone[6,7-b]pyrrolo[1,2-a-]-imidazolin-1-one derivatives (IIIa-f) or the 5-arvlidene-2-thioxo-4-imidazolinone derivatives(IVa-f). The activity of the NH in the imidazol moiety of (IIIa) was confirmed by formation of the Mannich bases (Va, b). Moreover, alkylation of (IIIa) was undertaken to give the alkylmercapto derivatives (VIa, b). The antimicrobial activities of compounds IIIb-e, IVa, IVe were studied.

• YAKHAK HOEJI
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• v.48 no.3
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• pp.202-206
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• 2004

New asymmetric dimers, N,N'-dialkyl-4'-hydroxy-4-oxo-2,2',3,3'-tetrahydro-2,2'-diphenyl-4,4'-quinolones 3a-f were synthesized through the dehydration and dea1coholation of N-alkylanilines and ethyl benzoylacetate. Dimers 3a-f were identified by NMR, IR and GC-MS. A series of dimer 3a-f has been synthesized using acid-catalyzed one-pot reaction that involved the condensation, cyc1ization and dimerization. Similarly, the 6,6'-methoxy (or 7,7'-methoxy) substituted dimers were prepared from N-alkyl-meta-(or para)-anisidines. Formation of dimers was undertaken with p-toluenesulfonic acid (p-TSA) at 90∼11$0^{\circ}C$ in toluene for 2∼6 hours over the Dean-Stark apparatus.

• Natural Product Sciences
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• v.6 no.1
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• pp.16-19
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• 2000

Four compounds were isolated from the dichloromethane fraction of Cinnamomi Cortex through bioassay-guided isolation. Their structures were identified as coumarin (1), 3,3-dimethoxy-1-propenyl benzene (2), cinnamic acid (3) and o-methoxy cinnamaldehyde (4) on the basis of spectroscopic data. All four compounds showed inhibitory activities in vitro against monoamine oxidase (MAO) prepared by mouse brain. The $IC_{50}$ values were $41.4\;{\mu}M\;(1),\;110.6\;{\mu}M\;(2),\;252.5\;{\mu}M\;(3)\;and\;83.1\;{\mu}M$ (4), respectively.