• Proceedings of the PSK Conference
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• 2003.04a
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• pp.237.1-237.1
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• 2003

(2S 3R. 4E) 5-Aryl-4-pentene-1,3-diol-2-aminoueras had been synthesized for their cytotoxic activity. Pinene was oxidized with KMnO4 to give 2-hydroxy-3-pinanone. which treated with ethyl glycinate to yield iminoglycinate and then reacted with aldehyde derivatives and titanium enolate to afford 3-hydroxy aldol compounds. (omitted)

• Archives of Pharmacal Research
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• v.13 no.2
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• pp.201-203
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• 1990

The efficient synthetic routes to cis-1-ethenyl-2-hydroxymethyl-cyclohexane, an useful synthetic intermediate, have been described. Access to the cis-disubstituted cyclo hexane is gained through the Clasen rearrangment and selective DHP protection of diol respectively.

• Journal of the Korean Wood Science and Technology
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• v.28 no.4
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• pp.25-28
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• 2000

Two flavan 3,4-diol derivatives were isolated from the heartwood of Robinia pseudoacacia and characterized by spectroscopic methods including $^1H$ and $^{13}C$ NMR and positive FAB-MS. The structures were identified as 2,3-trans-3,4-cis-3,4,7,3',4',5'-hexahydroxy flavan, one of isomeric leucorobinetinidins, and 4'-methoxy-2,3-trans-3,4-cis-3,4,7,3',5'-pentahydroxy flavan.

• Korean Journal of Food Science and Technology
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• v.35 no.3
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• pp.399-404
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• 2003

Aliphatic polyester, especially poly(butylene adipate)(PBA), is quite biodegradable and one of the most promising polymer materials to be commercialized. Bis(4-hydroxybutyl) adipate (BHBA) formation stage is the first principal process in the production of PBA from adipic acid (AA) and 1,4-butane diol (BD). In this study, we investigated for the effective production of Bis(4-hydroxybutyl) adipate (BHBA), effects of molar ratio of adipic acid (AA) to 1,4-butane diol (BD), catalyst (tetrabutyl titanate, TBT) concentration, and temperature on the reaction rate of esterification between AA and BD were investigated. Initial reaction rate of the esterification decreased with increasing molar ratio of AA to BD and reaction temperature, whereas reaction constant increased with increase in catalyst-concentration. Activation energy values for catalyzed and uncatalyzed esterifications were 198.5 and 94.8 kJ/mol, respectively.

• Korean Chemical Engineering Research
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• v.54 no.2
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• pp.175-180
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• 2016

The fluorine-containing modified polyurea was synthesized using the PTPE-diol to improve the ozone-resistance. Three types (PFDIA-10C, PFDIA-20C, PFDIA-30C) of the modified polyurea containing the fluorine content from 10 wt% to 30 wt% were prepared. After ozone treatment on the prepared films, the weight loss of film was investigated and analyzed the film properties such as hardness, wear resistance, tensile stress, elongation, etc. Also, the film surfaces were observed by the optical microscopy after ozone-resistance tests at 10 ppm for 336 h. It was shown that the defects such as the cracking, the bleaching and the mass loss were reduced and the ozone-resistance of films were improved when the contents of PFPE-diol are more than 20 wt%. It was found that the intensity of O-H peak in PFDIA compounds confirmed by FT-IR was decreased as fluorine contents were increasing.

• Natural Product Sciences
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• v.29 no.1
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• pp.10-16
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• 2023

We previously reported that dried Lysimachia christinae whole plant extract exerted significant neuroprotective activity. In this study, we tried to isolate neuroprotective compounds of L. christinae. We evaluated the neuroprotective activity of the four fractions (hexane, chloroform, ethyl acetate, and n-butanol fractions) of methanol extract. Among them, ethyl acetate and n-butanol fractions showed most potent neuroprotective activity against glutamate excitotoxicity. Nine compounds were isolated from ethyl acetate and n-butanol fractions of L. christinae extract and identified as cynaroside (1), (3,4,5,6-tetrahydroxytetrahydro-2H-pyran-2-yl)methyl-3-hydroxy-2-octyldopentaconta-23,33-dienoate (2), androst-16-ene-3,6-diol (3), 2-hydroxy-24-propoxytetracos-4-enoic acid (4), 2-hydroxy-24-methoxytetracos-4-enoic acid (5), 12-(stearoyloxy)octadec-9-enoic acid (6), β-sitosterol (7), (E)-4-(3,4-dimethoxyphenyl)but-3-en-1-yl palmitate (8) and (1S,2S,3R,4R)-4-(((2S,3R,4R,5R,6S)-2-(((2R,3R,4S,5R,6R)-2-(3,4-dimethoxyphenethoxy)-3,5-dihydroxy-6-(hydroxymethyl) tetrahydro-2H-pyran-4-yl)oxy)-4,5-dihydroxy-6-methyltetrahydro-2H-pyran-3-yl)oxy)cyclohexane-1,2,3-triol (9) by spectroscopic data such as UV, IR, NMR, Mass spectroscopy. Their neuroprotective activity was evaluated by MTT assay. Cynaroside (1) and androst-16-ene-3,6-diol (3) had significant neuroprotective activity against glutamate-injured HT22 cells. The neuroprotective efficacy of cynaroside (1) and androst-16-ene-3,6-diol (3) was related to their anti-oxidative activity.

• The Journal of Natural Sciences
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• v.8 no.2
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• pp.27-34
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• 1996

The phagocytosis and chemotaxis of murine macrophages after treated with saponin fractions are investigated. Phagocytic appearance against yeast was photographed by dying with Wright-Giemsa. Phagocytic activity of peritoneal macrophage was invreased in diol saponin treatment by 48% and was decreased in total saponin treatment by 35%. The ingestion of alveolar macrophage was increased by 50% maximally. Peritoneal chemotactic activity was shown in 17% increases and only diol saponin had effect in alveolar macrophage by 16%. According to SDS-PAGE method the contents of actin did not show any alterations.

• Clean Technology
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• v.5 no.2
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• pp.37-44
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• 1999

The influence of the reactant composition on the surface free energy and on the dispersity in water was investigated by using the fluorine-containing water-soluble polyurethane synthesized with the fluorine-containing diol and hydrophilic diol. The diol donating ionic characteristics was more effective than polyol, and stable emulsion with the diameter of 610~310 nm was obtained in the range of 0.3~0.7 molar ratio of the diol to polyol. According to the increment of fluorine-containing compound up to 10 wt %, the surface free energy of polyurethane was dramatically decreased from 22.3 to 12.6 dyn/cm, and the diameter of water dispersed polyurethane increased from 380 to 860 nm due to the strong interaction between polymer molecules because fluorine segments are arranged on the surface of molecules. The macromonomer with perfluoroalkyl group was more effective in complement of the weak point of water-soluble polyurethane, which is a decrease of hydrophobicity, because of strong hydrophobicity.

• Journal of Food Hygiene and Safety
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• v.22 no.4
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• pp.306-310
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• 2007

As a preliminary study for risk assessment of 3-monochloropropane-1,2-diol (3-MCPD) from processed food, the levels of 3-MCPD in commercial sauces and instant fried noodle (ramyun) seasoning were analyzed with gas chromatography/mass spectrometry. In August and September 2005, twenty-five samples of commercial sauces and twenty-five samples of instant fried noodle (ramyun) seasoning were collected from retail outlets and markets in Seoul, Korea. Six out of twenty-five sauces contained 3-MCPD and the highest concentration was 0.045 mg/kg. On the basis of per capita consumption of sauces and mean concentration of 3-MCPD, the estimated daily exposure to 3-MCPD from sauces was $0.094{\mu}g/person/day$. None of the twenty-five instant fried noodle (ramyun) seasoning samples was contained 3-MCPD. Therefore consumption of instant fried noodle (ramyun) seasoning was estimated not to contribute dietary exposure to 3-MCPD.

• Journal of the Korean Chemical Society
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• v.23 no.3
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• pp.180-185
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• 1979

Electrochemical reduction behavior from 2-butyne-1, 4-diol (BID) to 2-butene-1,4-diol (BED) by the use of various cathodes, such as Ti, Zr, Ni, Pt, Cu, Ag, Au, Zn, Hg, Pb and graphite has been studied. It has been found that cathodic polarization curve with metal of IB subgroup such as Cu, Ag and Au consisted of one wave in BID-alkaline solution, whereas it was not formed any wave in BED solution. Therefore, it was found that the cathode which was the most suitable in order to proceed in this reaction was Cu, Ag and Au. At cyclic voltammetry using a silver cathode in BID-alkaline solution, the current of the peak was proportional to square root of the sweep rate of potential and also proportional to concentration of BID. Activation energy was calculated for 3.75 kcal/mole from the plot of log $I_l$ vs. 1/T. Consequently, the reduction current of BID with a silver cathode in alkaline solution was found the diffusion current.