Search | Korea Science

Barakat, Assem;Al-Majid, Abdullah Mohammed;Al-Qahatany, Faisal M.;Islam, Mohammad Shahidul;Al-Agamy, Mohamed H.M.
- Bulletin of the Korean Chemical Society
- /
- v.35 no.2
- /
- pp.562-568
- /
- 2014
In this work, synthesis, characterization and antimicrobial activity of series of imidazolines-oxazolines scaffolds 5a-f and 10a-d have been investigated. All the imidazolines-oxazolines derivatives were prepared from acid derivatives 1 and 6a-c, and enantiomerically pure (S)-2-amino-3-methyl-1-butanol in four steps with excellent optical purity. The structures of all newly synthesized compounds have been elucidated by $^1H$, $^{13}C$ NMR, GCMS, and IR spectrometry. Their purity was confirmed using elemental analysis. Some newly synthesized compounds were examined to in-vitro antimicrobial activity. Among the prepared products 10d was found to exhibits the most active against all tested bacteria and fungi with minimal inhibitory concentration (MIC) ranged between 21.9 and $42.6{\mu}g/mL$.
https://doi.org/10.5012/bkcs.2014.35.2.562 인용 PDF KSCI KPUBS HTML

Hoogenboom Richard;Schubert Ulrich S.
- Proceedings of the Polymer Society of Korea Conference
- /
- 2006.10a
- /
- pp.199-199
- /
- 2006
Microwave-irradiation has become a common heat source in organic chemistry in the last decade. In recent years, polymer chemists also discovered the advances of microwave heating that include fast and efficient heating as well as the homogeneous heat profile and the easy access to pressurized reaction conditions. In this contribution, we report our investigations on the cationic ring-opening polymerization of 2-oxazolines that lead to a tremendous acceleration from several days to several minutes polymerization time. In addition, the optimized microwave-assisted polymerization procedure was applied for the preparation of libraries of diblock and triblock copolymers that were used for the determination of structure-property relationships in poly(2-oxazoline)s.
PDF