• 제목/요약/키워드: 2-Loop Structure

검색결과 455건 처리시간 0.024초

서울시민의 보행과 건강증진에 관한 시스템 사고 기반의 구조 탐색 (A systems thinking approach to explore the structure of urban walking and health promotion in Seoul)

  • 김동하;정창권;이지현;김광기;제갈정;유승현
    • 보건교육건강증진학회지
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    • 제35권5호
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    • pp.1-16
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    • 2018
  • Objectives: This study aimed to examine systems behavior of urban walking by analyzing a dynamic structure in Seoul, South Korea. Methods: As a systems thinking approach to urban walking and health promotion, we developed a Casual Loop Diagram based on literature review and expert consultation. The reviewed literature included: 1) qualitative studies that explores the experiences of urban walkers in Seoul; 2) a systematic review study on the built environmental factors related to walking; 3) policy research reports related to urban walking in Seoul. Results: The feedback structure for urban walking was related to the three urban environments (safety & walking environment, socioeconomic environment, and public transportation environment), and was characterized by a trade-off consisting of eight reinforcing loops and four balancing loops. Conclusions: The policies for a walkable city require multi-sectoral cooperation in order to change the causal loop structure related to the decline of walking. Therefore, it is necessary to establish legal and institutional conditions so that multi-sectoral and multidisciplinary approaches are possible.

Crystal Structure of Cytochrome cL from the Aquatic Methylotrophic Bacterium Methylophaga aminisulfidivorans MPT

  • Ghosh, Suparna;Dhanasingh, Immanuel;Ryu, Jaewon;Kim, Si Wouk;Lee, Sung Haeng
    • Journal of Microbiology and Biotechnology
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    • 제30권8호
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    • pp.1261-1271
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    • 2020
  • Cytochrome cL (CytcL) is an essential protein in the process of methanol oxidation in methylotrophs. It receives an electron from the pyrroloquinoline quinone (PQQ) cofactor of methanol dehydrogenase (MDH) to produce formaldehyde. The direct electron transfer mechanism between CytcL and MDH remains unknown due to the lack of structural information. To help gain a better understanding of the mechanism, we determined the first crystal structure of heme c containing CytcL from the aquatic methylotrophic bacterium Methylophaga aminisulfidivorans MPT at 2.13 Å resolution. The crystal structure of Ma-CytcL revealed its unique features compared to those of the terrestrial homologues. Apart from Fe in heme, three additional metal ion binding sites for Na+, Ca+, and Fe2+ were found, wherein the ions mostly formed coordination bonds with the amino acid residues on the loop (G93-Y111) that interacts with heme. Therefore, these ions seemed to enhance the stability of heme insertion by increasing the loop's steadiness. The basic N-terminal end, together with helix α4 and loop (G126 to Y136), contributed positive charge to the region. In contrast, the acidic C-terminal end provided a negatively charged surface, yielding several electrostatic contact points with partner proteins for electron transfer. These exceptional features of Ma-CytcL, along with the structural information of MDH, led us to hypothesize the need for an adapter protein bridging MDH to CytcL within appropriate proximity for electron transfer. With this knowledge in mind, the methanol oxidation complex reconstitution in vitro could be utilized to produce metabolic intermediates at the industry level.

500 Hz급 엑시머레이저의 반복동작특성 (Repetitive operation characteristics of 500 Hz class excimer laser)

  • 박홍진;이주희
    • 한국광학회지
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    • 제7권3호
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    • pp.232-237
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    • 1996
  • 대기오염 원격측정용 LIDAR의 레이저광으로 사용하기 위해 반복율 500Hz급 엑시머 에리저를 개발하고 이의 고반복 에이저 출력특성, 레이저 가스의 유로구조와 CR특성을 조사하였다. 레이저 장치는 유선형의 가스유로, 주전극 직렬 UV 예비전리방식 등의 방법을 사용하고 컴팩트한 구조로 제작하여 가스 실용적을 10 liter 이하로 소형화하였다. KrF 레이저를 500Hz로 동작할 때의 최대출력은 53watt, 출력변동율은 .+-.6.7%, CR은 2.3, 방전체적은 2.0(H)*1.2(W)*56(L)=134$cm^{3}$ 이다. 이때 초기 출력에너지의 50%까지 출력이 감소할 때의 레이저가스의 수명은 3*$10^{6}$ shots이다.

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FIV 시험루프의 유동기인 진동 신호분석 (Flow-Induced Vibration Signal Analysis of the FIV Test Loop)

  • 이강희;강흥석;윤경호;송기남
    • 대한기계학회:학술대회논문집
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    • 대한기계학회 2004년도 추계학술대회
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    • pp.601-606
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    • 2004
  • Vibration spectrums of the test loop according to flow conditions were analyzed in order to identify the sources of vibration at peak frequencies. While a flow condition of the sweep test was changed by varying pump rotational speed from 450 rpm to 1500 rpm by the step 150 rpm, midspan acceleration of the test section in width-direction and dynamic pressure perturbation in the test section were measured. Other sources of vibration due to the flow structure interactions, such as acoustic resonance, blade pulsing frequency and bellows wrinkles, were investigated. Pressure perturbation in the section and acoustic resonance due to branch pipe give major effects to the vibration of the test section in high frequency range of 1.5 kHz to 2.8 kHz.

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외란 제거 제어기를 이용한 강인 제어기의 설계 (Design of a Robust Controller Using Disturbance Rejection Controller)

  • 여희주
    • 한국산학기술학회논문지
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    • 제7권2호
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    • pp.137-144
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    • 2006
  • 본 논문에서는 시스템 파라미터의 변동이나 모델의 불확실성 및 외부 외란 등에 강인한 외란 관측기에 기초로 한 강인 제어기의 설계를 제안한다. 제어기는 두 개 루프의 구조를 갖는 모델기반 보상기와 궤환 제어기 구조로 구성되어 있다. 내부 루프 보상기는 내외부의 외란을 제거하고, 외부 루프 궤환 제어기는 주어진 사양을 만족하도록 하는 역할을 수행한다. 결과적으로, 제안한 강인 제어기를 이용함으로써 외란에 대해 시스템을 안정화 시킬 수 있으며, 제어 성능을 향상시킬 수 있음을 보인다.

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자속구속형 초전도 전류제한기의 철심조건에 따른 특성 (Characteristics of the Flux-lock Type Superconducting Fault Current Limiter According to the Iron Core Conditions)

  • 남긍현;이나영;최효상;조금배
    • 조명전기설비학회논문지
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    • 제20권7호
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    • pp.38-45
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    • 2006
  • 초전도전류제한기(SFCL)는 전력계통내 적용시 계통보호를 보다 향상시킬 수 있는 방안으로써 수초이내에 신속하게 사고전류를 제한한다. 이러한 SFCL중 자속구속형 전류제한기의 설계구조는 자속구속리액터인 하나의 철심에 1차측과 2차측 코일이 병렬로 결선되어 있다. 또한 전류제한소자인 YBCO박막과 2차측 코일을 직렬로 결선하여 설치장소의 조건에 따라 인덕턴스와 2차측 코일의 극성방향으로 과도전류 크기를 조절할 수 있다. 이러한 동작특성은 철심을 자속매개체로 적용되기 때문에 철심조건에 따른 성능평가실험은 필수적이다. 가극결선에서 전원전압을 200[Vrms] 인가시 피크전류는 폐루프가 30.71[A], 개루프가 32.01[A]까지 상승됨에 따라 초기과도 응답특성은 폐루프가 유리하였다. 하지만, 소자에 발생되는 전압이 폐루프가 220.14[V], 개루프가 142.73[V]까지 상승함에 따라, 폐루프 철심구조시 전류제한소자의 부담이 가중됨을 알 수 있었다. 결과적으로 자속구속형 SFCL의 전력계통내 적용 시 각각의 철심구조에 따른 다양한 운전특성을 적절히 설계시 장점을 극대화 할 수 있을 것이다.

Application of multi dimensional NMR experiments to VBS RNAs of Yeast Saccaromyces cerevisiae virus

  • Chaejoon Cheong;Cheong, Hae-Kap;Yoo, Jun-Seok
    • 한국자기공명학회논문지
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    • 제5권1호
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    • pp.29-36
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    • 2001
  • The structures of two VBS (viral binding site) RNAs, SL1 and SL2, of Yeast Saccharomyces cerevisiae vims have been studied by 2D and 3D NMR experiments. VBSs play a crucial role in viral particle binding to the plus strand and packaging of the RNA. The secondary structures of the two VBS RNAs share a common feature of the stem-internal loop-stem-hairpin loop structure although the size of the internal loops of SL1 and SL2 differs. 2D experiments were sufficient for fill assignments of SL1. However, isotope labeling of the sample and multidimensional experiments were required for 28-nucleotide-long SL2 due to the spectral overlap. Several 3D HCCH experiments have accomplished full assignment of SL2 RNA.

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루프소기방식을 갖는 2행정 프리피스톤 수소기관의 역화에 관한 연구 (Study on Backfire for a Two-Stroke Hydrogen Fueled Free-Piston Engine with Loop Scavenging)

  • 조관연;변창희;백대하;이종태
    • 한국수소및신에너지학회논문집
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    • 제21권6호
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    • pp.487-492
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    • 2010
  • For developing a two-stroke free-piston hydrogen engine with high efficiency and low emission, determination of the scavenging type is one of the most important factor. In this research, backfire characteristics for loop scavenging were analyzed with the number of piston crevice volume and piston expansion speed. Rapid Compression Expansion Machine, RCEM was used for combustion research of the free piston $H_2$ engine in the experiment. As the results, it was shown that although backfire occurring in a loop scavenging type can be partially controled by a complete exhaust of burned gas, possibility of backfire basically exist due to the structure which piston crevice volumes contact with fresh mixture in a scavenging port. However, a loop scavenging may be considered as combustion chamber of a free piston $H_2$ engine from the point of view that backfire does not occur nearby lean equivalence ratio obtained high thermal efficiency. It was also analyzed that an advances of backfire occurrence timing with increase of the fuel-air equivalence ratio were due to promotion of flame propagation into piston crevice volumes by decrease of the quenching distance.

4중 대역을 포함하는 휴대폰용 재구성 안테나 (A Reconfigurable Antenna for Quad-Band Mobile Handset Application)

  • 박영근;성영제
    • 한국전자파학회논문지
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    • 제23권5호
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    • pp.570-582
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    • 2012
  • 본 논문에서는 핀 다이오드를 사용하여 4중 대역(GSM900/GSM1800/GSM1900/UMTS)을 포함하는 휴대폰 용 재구성 안테나를 제안하였다. 제안한 안테나의 크기는 $45{\times}11{\times}6mm^3$이다. 안테나 패턴 위에 위치한 두 개의 핀 다이오드를 독립적으로 조절하여 다이오드가 on/off 됨에 따라 각각 Planar Inverted-F Antenna(PIFA) mode와 loop mode로써 동작하게 하였다. 재구성 안테나의 설계를 검증하기 위해 핀 다이오드 대신 conducting tape을 사용하여 prototype을 설계, 제작, 실험하였다. 제작한 재구성 안테나에서 PIFA 모드로 동작할 때의 측정 결과는 7 dB 대역폭이 8.62 %(880~960 MHz)이며, GSM900(880~960 MHz) 대역을 포함한다. Loop 모드로 동작할 때의 측정결과는 7 dB 대역폭이 26.36 %(1,696~2,240 MHz)로 GSM1800(1,710~1,880 MHz)/GSM1900(1,850~1,990 MHz)/UMTS(1,920~2,170 MHz)대역을 포함한다.

Structural Studies on IRES 4-2 Domain of Foot-and-mouth Disease Virus

  • Kim, Young-Mee;Yoo, Jun-Seok;Cheong, Hae-Kap;Lee, Chul-Hyun;Cheong, Chae-Joon
    • 한국자기공명학회논문지
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    • 제7권2호
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    • pp.89-97
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    • 2003
  • Foot-and-mouth disease virus (FMDV) belongs to the aphthovirus genus within the picornavirus which has a single copy of a positive sense RNA. The translation initiation process of FMDV occurs by a cap-independent mechanism directed by a highly structured element (∼435 nt) termed an internal ribosome entry site (IRES). We have designed and prepared FMDV 4-2 RNA (28nt) by in vitro transcription. The 2D NMR data revealed that FMDV 4-2 IRES domain RNA has a flexible loop and bulge conformation. In further study, we need to make an isotope labeled RNA sample and conduct 3D NMR experiments to completely determine the 3D structure. This study may establish a new drug design strategy to treat foot-and mouth disease.

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